DrugRepV_0012 | BHSA | NA | NA | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | No significant effect (45 %) | NA | 29033372 |
DrugRepV_0015 | Chlorogenic Acid | NA | Cancer | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | No significant effect (10 %) | Investigational | 29033372 |
DrugRepV_0016 | Tetrandrine | NA | Congestive circulatory disorder and inflammatory diseases | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | No significant effect (0 %) | Experimental | 29033372 |
DrugRepV_0019 | Delphinidin Chloride | NA | NA | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | Increase (110 %) | NA | 29033372 |
DrugRepV_0073 | Sunitinib-Erlotinib | NA | NA | Ebola virus | rVSV-GP EBOV | NA | Flow cytometry | Decrease | NA | 28240606 |
DrugRepV_0074 | Sunitinib-Erlotinib | NA | NA | Ebola virus | Mouse adapted strain | NA | NA | Increase | NA | 28240606 |
DrugRepV_0090 | Imukin | NA | NA | Zika virus | Puerto Rico strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 28185815 |
DrugRepV_0091 | Imukin | NA | NA | Zika virus | Puerto Rico strain PRVABC-59 | NA | Real-time PCR | Decrease (>2 Log viral titer (copies/ml)) | Approved, Investigational | 28185815 |
DrugRepV_0092 | Imukin | NA | NA | Zika virus | Puerto Rico strain PRVABC-59 | NA | Plaque assay | Decrease (>90 %) | Approved, Investigational | 28185815 |
DrugRepV_0097 | Ki8751 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 28099856 |
DrugRepV_0100 | GSK2656157 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect | NA | 28099856 |
DrugRepV_0110 | RGFP966 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 28099856 |
DrugRepV_0116 | Methotrexate | NA | Gestational choriocarcinoma | Chorioadenoma destruens | Hydatidiform mole | Meningeal leukemia | Breast cancer | Epidermoid cancers of the head and neck | Lung cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 28099856 |
DrugRepV_0117 | PF-04691502 | NA | Breast Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect | Investigational | 28099856 |
DrugRepV_0120 | Navitoclax | NA | Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 28099856 |
DrugRepV_0123 | GZD824 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect (No significant effect No significant effect) | NA | 28099856 |
DrugRepV_0124 | VE-822 | NA | Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect (No significant effect No significant effect) | Investigational | 28099856 |
DrugRepV_0125 | Amuvatinib | NA | Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect (No significant effect No significant effect) | Investigational | 28099856 |
DrugRepV_0126 | NVP-BHG712 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect (No significant effect No significant effect) | NA | 28099856 |
DrugRepV_0127 | WAY-600 | NA | Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 28099856 |
DrugRepV_0128 | YM201636 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect | NA | 28099856 |
DrugRepV_0129 | RGFP966 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 28099856 |
DrugRepV_0130 | QNZ | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 28099856 |
DrugRepV_0133 | STF-118804 | NA | NA | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 28099856 |
DrugRepV_0144 | AMG-458 | NA | Cancer | Zika virus | MR766 | NA | Immunoflourescence assay | Decrease (60 %) | NA | 28099856 |
DrugRepV_0145 | AMG-458 | NA | Cancer | Zika virus | MR766 | NA | Immunoflourescence assay | No significant effect (20 %) | NA | 28099856 |
DrugRepV_0146 | AMG-458 | NA | Cancer | Zika virus | MR766 | NA | Immunoflourescence assay | No significant effect (10 %) | NA | 28099856 |
DrugRepV_0165 | AMG-458 | NA | Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (60 %) | NA | 28099856 |
DrugRepV_0166 | AMG-458 | NA | Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | Decrease (70 %) | NA | 28099856 |
DrugRepV_0167 | AMG-458 | NA | Cancer | Zika virus | Mex2-81 | NA | Immunoflourescence assay | No significant effect (30 %) | NA | 28099856 |
DrugRepV_0205 | Toremifene-Clarithromycin-Posaconazole | NA | NA | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27890675 |
DrugRepV_0206 | Toremifene-Mefloquine-Posaconazole | NA | NA | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27890675 |
DrugRepV_0207 | Chloroquine-Maprotiline-Azithromycin | NA | Malaria and Depression | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0213 | Toremifene-Clarithromycin-Posaconazole | NA | NA | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (>90 %) | NA | 27890675 |
DrugRepV_0214 | Toremifene-Mefloquine-Posaconazole | NA | NA | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (74 %) | NA | 27890675 |
DrugRepV_0217 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.72 ± 0.18 Ct) | Investigational | 27801778 |
DrugRepV_0218 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?0.63 ± 1.39 Ct) | Investigational | 27801778 |
DrugRepV_0231 | JB1a | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?4.02 ± 0.13 Ct) | NA | 27801778 |
DrugRepV_0232 | JB1a | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?5.48 ± 0.50 Ct) | NA | 27801778 |
DrugRepV_0239 | Aimspro | NA | Multiple sclerosis | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.03 ± 0.95 Ct) | Phase II | 27801778 |
DrugRepV_0240 | Aimspro | NA | Multiple sclerosis | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?4.60 ± 1.15 Ct) | Phase II | 27801778 |
DrugRepV_0241 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (>10 Ct) | NA | 27801778 |
DrugRepV_0242 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (>10 Ct) | NA | 27801778 |
DrugRepV_0252 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.44 ± 0.06 Ct) | Investigational | 27801778 |
DrugRepV_0257 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (1.54 ± 0.44 Ct) | NA | 27801778 |
DrugRepV_0259 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | NA | No significant effect | Investigational | 27801778 |
DrugRepV_0261 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | NA | No significant effect | NA | 27801778 |
DrugRepV_0302 | PIK-75 | NA | NA | Influenza virus | A/Anhui/1/ 2013 | | Immunoflourescence assay | Decrease (50 %) | NA | 26192013 |
DrugRepV_0303 | PIK-75 | NA | NA | Influenza virus | A/California/04/09 | | Immunoflourescence assay | Decrease (50 %) | NA | 26192013 |
DrugRepV_0304 | PIK-75 | NA | NA | Influenza virus | A/Philippines/2/82-X79 | | Immunoflourescence assay | Decrease (50 %) | NA | 26192013 |
DrugRepV_0309 | PIK-75 | NA | NA | Influenza virus | A/Mississippi/3/01 wt | | TCID50 assay | Decrease (~1 Log10 virus titer (TCID50/ml)) | NA | 26192013 |
DrugRepV_0310 | PIK-75 | NA | NA | Influenza virus | A/Mississippi/3/01 H275Y | | TCID50 assay | Decrease (~1 Log10 virus titer (TCID50/ml)) | NA | 26192013 |
DrugRepV_0315 | PIK-75 | NA | NA | Influenza virus | A/Mississippi/3/01 wt | | Immunoflourescence assay | Decrease (90 %) | NA | 26192013 |
DrugRepV_0316 | PIK-75 | NA | NA | Influenza virus | A/Mississippi/3/01 H275Y | | Immunoflourescence assay | Decrease (85 %) | NA | 26192013 |
DrugRepV_0406 | Quinacrine Dihydrochloride | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Investigational | 26041706 |
DrugRepV_0441 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Investigational | 26041706 |
DrugRepV_0469 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Investigational | 26041706 |
DrugRepV_0498 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Investigational | 26041706 |
DrugRepV_0551 | Tilorone | NA | Acquired immunodeficiency syndrome | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0559 | Nitrovin | NA | NA | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26038505 |
DrugRepV_0564 | Cyclomethycaine | NA | Anesthesia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Withdrawn | 26038505 |
DrugRepV_0567 | Azaclorzine | NA | Anginal | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26038505 |
DrugRepV_0712 | Aminoquinoline-13 | NA | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0716 | Aminoquinoline-13 | NA | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0720 | Aminoquinoline-13 | NA | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0724 | Aminoquinoline-13 | NA | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0772 | Dactinomycin | NA | Cancer | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (99.435 %) | Approved | 27476412 |
DrugRepV_0773 | Methotrexate | NA | Gestational choriocarcinoma | Chorioadenoma destruens | Hydatidiform mole | Meningeal leukemia | Breast cancer | Epidermoid cancers of the head and neck | Lung cancer | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (97.715 %) | Approved | 27476412 |
DrugRepV_0896 | Prilocaine Hydrochloride | NA | Anesthesia | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (53.97 %) | Approved | 27476412 |
DrugRepV_0955 | Guanfacine Hydrochloride | NA | Hypertension | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (53.975 %) | Approved, Investigational | 27476412 |
DrugRepV_0985 | Mestranol | NA | Contraception | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.56 %) | Approved | 27476412 |
DrugRepV_0989 | Ursodiol | NA | Gallstone and cholestatic forms of liver diseases including primary biliary cirrhosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.78 %) | Approved | 27476412 |
DrugRepV_0997 | Metaxalone | NA | Musculoskeletal pain caused by strains, sprains, and other musculoskeletal conditions | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50.445 %) | Approved | 27476412 |
DrugRepV_1000 | Beclomethasone Dipropionate | NA | Allergic rhinitis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (51.25 %) | Approved | 27476412 |
DrugRepV_1033 | Zileuton | NA | Asthma | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.355 %) | Approved, Withdrawn | 27476412 |
DrugRepV_1039 | Tiludronate Disodium | NA | Paget disease | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.63 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1067 | Midodrine Hydrochloride | NA | Orthostatic Hypotension | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.235 %) | Approved | 27476412 |
DrugRepV_1115 | Niacin | NA | Hyperlipidemia | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.67 %) | Approved, Investigational, Nutraceutical | 27476412 |
DrugRepV_1149 | Rizatriptan Benzoate | NA | Migraine disorders | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.98 %) | Approved | 27476412 |
DrugRepV_1205 | Naringenin | NA | NA | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.34 %) | Experimental | 27476412 |
DrugRepV_1224 | Galantamine Hydrobromide | NA | Alzheimer's disease | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50.96 %) | Approved | 27476412 |
DrugRepV_1269 | Carglumic Acid | NA | Hyperammonaemia in patients with N-acetylglutamate synthase (NAGS) deficiency | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.855 %) | Approved | 27476412 |
DrugRepV_1290 | Gentamycin Sulfate | NA | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.715 %) | Approved | 27476412 |
DrugRepV_1337 | Phytonadione | NA | Haemorrhagic conditions in infants | Antidote for coumarin anticoagulants in hypoprothrombinaemia | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.655 %) | Approved, Investigational | 27476412 |
DrugRepV_1353 | Tetrahydrozoline Hydrochloride | NA | Discomfort and redness of the eye due to minor eye irritations | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (43.315 %) | Approved | 27476412 |
DrugRepV_1394 | Tinidazole | NA | Trichomonasis | Amebiasis | Giardiasis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.3 %) | Approved | 27476412 |
DrugRepV_1417 | Difluprednate | NA | Anterior uveitis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (41.575 %) | Approved | 27476412 |
DrugRepV_1511 | Acyclovir Zovirax | NA | Viral infections (Herpes simplex, Zoster and varicella zoster) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.46 %) | Approved | 27476412 |
DrugRepV_1564 | Desmethyl Erlotinib | NA | Cancer | Rift Valley fever virus | MP12-Luc | NA | Luciferase reporter assay | Decrease (65 %) | Approved, Investigational | 26217313 |
DrugRepV_1615 | Quinacrine Hydrochloride | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Investigational | 26834994 |
DrugRepV_1617 | Tilorone Dihydrochloride | NA | Viral infections | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | NA | 26834994 |
DrugRepV_1623 | Lavendustin A | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1628 | D-serine | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | Approved | 24991006 |
DrugRepV_1632 | 2,2-Dipyridyl Disulfide | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | Experimental | 24991006 |
DrugRepV_1635 | Pobilukast | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1636 | PD-180970 | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1637 | Methylanthraniloyl guanosine triphosphate | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1638 | Mastoparan | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1639 | Hexadimethrine Bromide | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1640 | Dideooxyforskolin | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1641 | Compound 48/80 | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1642 | 3-(N-methylanthraniloyl)-2-deoxy-ATP | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1643 | 3-Aminotriazole | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1644 | 2/3-O-N-methyanthraniloyl-ITP-gamma-S | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1645 | 2/3-O-N-methyanthraniloyl-GTP-gamma-S | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1646 | 2-(or3)-O-(N-methylanthranioyl)ATP | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1647 | 2-Aminopurine | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1648 | 1-cyclopropyl-3 | NA | NA | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | NA | 24991006 |
DrugRepV_1649 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | MR766 | NA | Cell viability assay | Decrease (98.7 %) | Investigational | 27571349 |
DrugRepV_1652 | Ensulizole | NA | Sunburn | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Approved | 27571349 |
DrugRepV_1654 | Isoliquirtigenin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1658 | Vidofludimus | NA | Crohn disease; Inflammatory bowel diseases and Rheumatoid arthritis | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1659 | SB-366791 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1660 | Emodin | NA | Polycystic Kidney | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1661 | Diphenyl isophthalate | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1662 | Benzoylpas | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1663 | Fenobam | NA | Fragile X Syndrome | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1665 | Drometrizole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1666 | PHA-690509 | NA | Cancer | Zika virus | MR766 | NA | Cell viability assay | Decrease (81.9 %) | NA | 27571349 |
DrugRepV_1670 | Cinanserin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1671 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1672 | Veliflapon | NA | Myocardial infarction (Heart attack) | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Phase III | 27571349 |
DrugRepV_1676 | Naringenin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1678 | Fanetizole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1681 | CAY10505 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1682 | Hesperetin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1687 | Piraxostat | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (34.7 %) | NA | 27571349 |
DrugRepV_1688 | Albendazole oxide | NA | Parasitic infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1689 | Tyrphostin AG 494 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1693 | RITA | NA | Cancer | Zika virus | MR766 | NA | Cell viability assay | Decrease (81.7 %) | NA | 27571349 |
DrugRepV_1695 | BF-170-hydrochloride | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (65.8 %) | NA | 27571349 |
DrugRepV_1697 | Tribromsalan | NA | Bacterial infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1698 | Pifexole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1699 | Formononetin | NA | Postmenopausal Osteopenia | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1701 | Tranilast | NA | Bronchial asthma | Keloid and hypertrophic scar | Allergic disorders such as asthma, allergic rhinitis | Atopic dermatitis | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1702 | Benzylparaben | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Approved, Experimental | 27571349 |
DrugRepV_1703 | 2-Ethoxylethyl-p-methoxycinnamate | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1705 | Nemorubicin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease | NA | 27571349 |
DrugRepV_1706 | Rutaecarpine | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1707 | MPEP | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1708 | 5,7-Dihydroxyflavone | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1711 | 2 Amino-6-nitrobenzothiazole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1713 | Enfenamic Acid | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1714 | Fenaminosulf | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1715 | AS-252424 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1716 | Phenserine | NA | Alzheimer's disease | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1718 | Alizarin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1720 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | MR766 | NA | Cell viability assay | Decrease | Investigational | 27571349 |
DrugRepV_1723 | Ensulizole | NA | Sunburn | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Approved | 27571349 |
DrugRepV_1725 | Isoliquirtigenin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (36.3 %) | Experimental | 27571349 |
DrugRepV_1729 | Vidofludimus | NA | Crohn disease; Inflammatory bowel diseases and Rheumatoid arthritis | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1730 | SB-366791 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1731 | Emodin | NA | Polycystic Kidney | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1732 | Diphenyl isophthalate | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1733 | Benzoylpas | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1734 | Fenobam | NA | Fragile X Syndrome | Zika virus | MR766 | NA | Cell viability assay | Decrease (60.5 %) | Investigational | 27571349 |
DrugRepV_1736 | Drometrizole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1737 | PHA-690509 | NA | Cancer | Zika virus | MR766 | NA | Cell viability assay | Decrease | NA | 27571349 |
DrugRepV_1741 | Cinanserin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (56.9 %) | NA | 27571349 |
DrugRepV_1742 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1743 | Veliflapon | NA | Myocardial infarction (Heart attack) | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Phase III | 27571349 |
DrugRepV_1747 | Naringenin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1749 | Fanetizole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1752 | CAY10505 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1753 | Hesperetin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1758 | Piraxostat | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (60.3 %) | NA | 27571349 |
DrugRepV_1759 | Albendazole oxide | NA | Parasitic infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Experimental | 27571349 |
DrugRepV_1760 | Tyrphostin AG 494 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (45.6 %) | NA | 27571349 |
DrugRepV_1764 | RITA | NA | Cancer | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1766 | BF-170-hydrochloride | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1768 | Tribromsalan | NA | Bacterial infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1769 | Pifexole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1770 | Formononetin | NA | Postmenopausal Osteopenia | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1772 | Tranilast | NA | Bronchial asthma | Keloid and hypertrophic scar | Allergic disorders such as asthma, allergic rhinitis | Atopic dermatitis | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1773 | Benzylparaben | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Approved, Experimental | 27571349 |
DrugRepV_1774 | 2-Ethoxylethyl-p-methoxycinnamate | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1776 | Nemorubicin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease | NA | 27571349 |
DrugRepV_1777 | Rutaecarpine | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1778 | MPEP | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1779 | 5,7-Dihydroxyflavone | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1782 | 2 Amino-6-nitrobenzothiazole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1784 | Enfenamic Acid | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1785 | Fenaminosulf | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (36.7 %) | NA | 27571349 |
DrugRepV_1786 | AS-252424 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1787 | Phenserine | NA | Alzheimer's disease | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1789 | Alizarin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1791 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | MR766 | NA | Cell viability assay | Decrease (54.4 %) | Investigational | 27571349 |
DrugRepV_1794 | Ensulizole | NA | Sunburn | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Approved | 27571349 |
DrugRepV_1796 | Isoliquirtigenin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Experimental | 27571349 |
DrugRepV_1800 | Vidofludimus | NA | Crohn disease; Inflammatory bowel diseases and Rheumatoid arthritis | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1801 | SB-366791 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1802 | Emodin | NA | Polycystic Kidney | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1803 | Diphenyl isophthalate | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1804 | Benzoylpas | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1805 | Fenobam | NA | Fragile X Syndrome | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Investigational | 27571349 |
DrugRepV_1807 | Drometrizole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1808 | PHA-690509 | NA | Cancer | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1812 | Cinanserin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1813 | 5-Nitro-2-(3-phenylpropylamino)benzoic Acid | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1814 | Veliflapon | NA | Myocardial infarction (Heart attack) | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Phase III | 27571349 |
DrugRepV_1818 | Naringenin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Experimental | 27571349 |
DrugRepV_1820 | Fanetizole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1823 | CAY10505 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1824 | Hesperetin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Experimental | 27571349 |
DrugRepV_1829 | Piraxostat | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1830 | Albendazole oxide | NA | Parasitic infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Experimental | 27571349 |
DrugRepV_1831 | Tyrphostin AG 494 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1835 | RITA | NA | Cancer | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1837 | BF-170-hydrochloride | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1839 | Tribromsalan | NA | Bacterial infections | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1840 | Pifexole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1841 | Formononetin | NA | Postmenopausal Osteopenia | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Investigational | 27571349 |
DrugRepV_1843 | Tranilast | NA | Bronchial asthma | Keloid and hypertrophic scar | Allergic disorders such as asthma, allergic rhinitis | Atopic dermatitis | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Investigational | 27571349 |
DrugRepV_1844 | Benzylparaben | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | Approved, Experimental | 27571349 |
DrugRepV_1845 | 2-Ethoxylethyl-p-methoxycinnamate | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1847 | Nemorubicin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1848 | Rutaecarpine | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1849 | MPEP | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1850 | 5,7-Dihydroxyflavone | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1853 | 2 Amino-6-nitrobenzothiazole | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1855 | Enfenamic Acid | NA | NA | Zika virus | MR766 | NA | Cell viability assay | Decrease (58.5 %) | NA | 27571349 |
DrugRepV_1856 | Fenaminosulf | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect | NA | 27571349 |
DrugRepV_1857 | AS-252424 | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1858 | Phenserine | NA | Alzheimer's disease | Zika virus | MR766 | NA | Cell viability assay | No significant effect | Investigational | 27571349 |
DrugRepV_1860 | Alizarin | NA | NA | Zika virus | MR766 | NA | Cell viability assay | No significant effect (0 %) | NA | 27571349 |
DrugRepV_1862 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | MR766 (1947 Ugandan strain) | NA | Cell viability assay | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1863 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | FSS13025 (2010 Cambodian strain) | NA | Cell viability assay | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1864 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Cell viability assay | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1865 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1866 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1867 | Emricasan | NA | Antiapoptotic and anti-inflammatory | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1870 | PHA-690509 | NA | Cancer | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | NA | 27571349 |
DrugRepV_1871 | PHA-690509 | NA | Cancer | Zika virus | NA | NA | Cell viability assay | Decrease (50 %) | NA | 27571349 |
DrugRepV_1872 | PHA-690509 | NA | Cancer | Zika virus | MR766 (1947 Ugandan strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1873 | PHA-690509 | NA | Cancer | Zika virus | FSS13025 (2010 Cambodian strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1874 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1875 | PHA-690509 | NA | Cancer | Zika virus | MR766 (1947 Ugandan strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1876 | PHA-690509 | NA | Cancer | Zika virus | FSS13025 (2010 Cambodian strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1877 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1880 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Enzyme-linked immunosorbent assay | Decrease | NA | 27571349 |
DrugRepV_1882 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Plaque assay | Decrease (50 %) | NA | 27571349 |
DrugRepV_1885 | PHA-690509 | NA | Cancer | Zika virus | FSS13026 | NA | Real-time PCR | Decrease (50 %) | NA | 27571349 |
DrugRepV_1887 | PHA-690509 | NA | Cancer | Zika virus | FSS13026 | NA | Real-time PCR | Decrease | NA | 27571349 |
DrugRepV_1890 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1891 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1893 | SNS-032 | NA | Cancer | Zika virus | FSS13026 | NA | NA | Decrease (50 %) | Investigational | 27571349 |
DrugRepV_1895 | AT7519 | NA | Cancer | Zika virus | FSS13026 | NA | NA | Decrease (50 %) | NA | 27571349 |
DrugRepV_1897 | RGB-286147 | NA | NA | Zika virus | FSS13026 | NA | NA | Decrease (50 %) | NA | 27571349 |
DrugRepV_1899 | Alvocidib | NA | Cancer | Zika virus | FSS13026 | NA | NA | Decrease (50 %) | Experimental | 27571349 |
DrugRepV_1900 | PHA-690509 | NA | Cancer | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1901 | Alvocidib | NA | Cancer | Zika virus | FSS13026 | NA | Western blot | Decrease (Decrease Band intensity) | Experimental | 27571349 |
DrugRepV_1905 | PHA-690509 | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | NA | 27571349 |
DrugRepV_1906 | Alvocidib | NA | Cancer | Zika virus | PRVABC-59 (2015 Puerto Rican strain) | NA | Western blot | Decrease (Decrease Band intensity) | Experimental | 27571349 |
DrugRepV_1965 | Fenretinide-Butylated Hydroxyanisole | NA | NA | Influenza virus | Strain A/PR8/ 34 | | Plaque assay | No significant effect | Investigational | 25313218 |
DrugRepV_2029 | Levonordefrin | NA | Dental disorders | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2070 | Phenothrin | NA | NA | Lassa virus | LASVpv | NA | Luciferase reporter assay | Decrease (50 %) | Experimental | 29899092 |
DrugRepV_2079 | Tiotidine | NA | NA | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2080 | Tiotidine | NA | NA | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2081 | Impentamine | NA | NA | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2082 | Impentamine | NA | NA | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2085 | Nordiphenhydramine | NA | NA | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | NA | 29981374 |
DrugRepV_2086 | Nordiphenhydramine | NA | NA | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | NA | 29981374 |
DrugRepV_2132 | 2-C-Methylcytidine | NA | Hepatitis C virus | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 27163257 |
DrugRepV_2133 | 2-C-Methylcytidine | NA | Hepatitis C virus | Zika virus | MR766 | NA | Virus yield reduction assay | Decrease (50 %) | Experimental | 27163257 |
DrugRepV_2134 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 27163257 |
DrugRepV_2135 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Virus yield reduction assay | Decrease (50 %) | NA | 27163257 |
DrugRepV_2136 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Plaque assay | Decrease (50 %) | NA | 27163257 |
DrugRepV_2137 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27163257 |
DrugRepV_2138 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Survival assay | Increase | NA | 27163257 |
DrugRepV_2139 | 7-deaza-2-C-methyl-D-adenosine | NA | Viral infection | Zika virus | MR766 | NA | Real-time PCR | Decrease | NA | 27163257 |
DrugRepV_2140 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2141 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2142 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2143 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2144 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2145 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Puerto Rican strain PRVABC-59 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2146 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2147 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2148 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2149 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2150 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2151 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2152 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2153 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2154 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase I | 27838352 |
DrugRepV_2155 | BCX4430 Dihydrochloride | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Virus yield reduction assay | Decrease (90 %) | Phase I | 27838352 |
DrugRepV_2177 | Avobenzone | NA | Sunburn | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (16.643533 %) | Approved | 27742486 |
DrugRepV_2215 | Fudosteine | NA | Bronchial asthma | Chronic bronchitis | Pulmonary emphysema | Bronchiectasis | Pulmonary tuberculosis | Pneumoconiosis | Atypical mycobacterial disease | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (7.62256156 %) | NA | 27742486 |
DrugRepV_2220 | Tylosin tartrate | NA | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (7.36358127 %) | Vet Approved | 27742486 |
DrugRepV_2235 | Arbidol Hydrochloride | NA | Influenza | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.59070859 %) | NA | 27742486 |
DrugRepV_2241 | Novobiocin Sodium | NA | Staphylococci infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.24445866 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2244 | Azacyclonol | NA | Psychosis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.14203789 %) | NA | 27742486 |
DrugRepV_2261 | Azasetron Hydrochloride | NA | Nausea and vomiting induced by cancer chemotherapy | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.49334625 %) | NA | 27742486 |
DrugRepV_2280 | OSI-420 | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.78127734 %) | NA | 27742486 |
DrugRepV_2294 | Daidzein | NA | Dietary supplement | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.45147852 %) | Experimental | 27742486 |
DrugRepV_2296 | Adenine Hydrochloride | NA | Nutritional supplement | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.42334798 %) | Approved | 27742486 |
DrugRepV_2323 | Geniposide | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.7860683 %) | NA | 27742486 |
DrugRepV_2329 | Chloroxine | NA | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.67704383 %) | Approved | 27742486 |
DrugRepV_2337 | Adiphenine Hydrochloride | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.4400476 %) | NA | 27742486 |
DrugRepV_2357 | Mecarbinate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.00956049 %) | NA | 27742486 |
DrugRepV_2370 | Cytidine | NA | Biopolar Depression | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.69043453 %) | Experimental | 27742486 |
DrugRepV_2381 | Niacin | NA | Hyperlipidemia | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.44049164 %) | Approved, Investigational, Nutraceutical | 27742486 |
DrugRepV_2388 | Albendazole oxide | NA | Parasitic infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.36721682 %) | Experimental | 27742486 |
DrugRepV_2392 | Geniposidic Acid | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.33842957 %) | NA | 27742486 |
DrugRepV_2399 | Paeoniflorin | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.22636429 %) | NA | 27742486 |
DrugRepV_2407 | Adenine | NA | Nutritional supplement | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.12499687 %) | Approved | 27742486 |
DrugRepV_2415 | Adenine Sulfate | NA | Nutritional supplement | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.95953472 %) | Approved | 27742486 |
DrugRepV_2465 | Sodium Butyrate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.80232337 %) | NA | 27742486 |
DrugRepV_2471 | Azelnidipine | NA | Hypertension | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.64469838 %) | Approved | 27742486 |
DrugRepV_2477 | Mestranol | NA | Contraception | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.44756785 %) | Approved | 27742486 |
DrugRepV_2488 | Aspartame | NA | Diet supplement and sugar substitute | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.28008959 %) | Approved | 27742486 |
DrugRepV_2494 | Curcumin | NA | Depressive disorder | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.21930657 %) | Approved | 27742486 |
DrugRepV_2515 | Talc | NA | Rashes | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.1085991 %) | Approved | 27742486 |
DrugRepV_2521 | Pregnenolone | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.2797662 %) | Approved, Experimental | 27742486 |
DrugRepV_2533 | Pimobendan | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.5850328 %) | Vet approved | 27742486 |
DrugRepV_2538 | Alibendol | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.6238122 %) | NA | 27742486 |
DrugRepV_2539 | Vicriviroc Malate | NA | AIDS | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.6325066 %) | Investigational | 27742486 |
DrugRepV_2542 | Sodium orthovanadate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.6967088 %) | NA | 27742486 |
DrugRepV_2545 | Irsogladine | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.8011514 %) | Investigational | 27742486 |
DrugRepV_2563 | Detomidine Hydrochloride | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.086047 %) | Approved, Vet Approved | 27742486 |
DrugRepV_2564 | Hydroxyflutamide | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.1400626 %) | NA | 27742486 |
DrugRepV_2570 | Ursodiol | NA | Gallstone and cholestatic forms of liver diseases including primary biliary cirrhosis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.242893 %) | Approved | 27742486 |
DrugRepV_2596 | Methacycline Hydrochloride | NA | Acute bacterial exacerbations of chronic bronchitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.5238499 %) | Approved, Investigational | 27742486 |
DrugRepV_2610 | 2-Methoxyestradiol | NA | Cancer | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.7014075 %) | Investigational | 27742486 |
DrugRepV_2619 | Nafamostat Mesylate | NA | Blood vessel coagulation | Hemorrhagic lesions | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.7795584 %) | Investigational | 27742486 |
DrugRepV_2623 | Liranaftate | NA | Fungal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.8068752 %) | NA | 27742486 |
DrugRepV_2625 | NAD | NA | Parkinson's disease | Chronic fatigue syndrome | Alzheimer's disease | Cardiovascular disease | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.8213385 %) | Approved | 27742486 |
DrugRepV_2633 | Zileuton | NA | Asthma | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.9379253 %) | Approved, Withdrawn | 27742486 |
DrugRepV_2650 | Bepotastine besilate | NA | Allergic rhinitis and uriticaria/puritus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.1704391 %) | Approved | 27742486 |
DrugRepV_2668 | Moguisteine | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.4037393 %) | NA | 27742486 |
DrugRepV_2683 | 10-DAB | NA | Cancer | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.5981982 %) | NA | 27742486 |
DrugRepV_2692 | Dextrose | NA | Hypoglycemia | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.8688015 %) | Approved | 27742486 |
DrugRepV_2709 | Arecoline | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.0469253 %) | Experimental | 27742486 |
DrugRepV_2746 | Gabexate Mesylate | NA | Cancer | Ischemia-reperfusion injury | Pancreatitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.7539063 %) | Investigational | 27742486 |
DrugRepV_2751 | Marbofloxacin | NA | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.8874309 %) | Vet approved | 27742486 |
DrugRepV_2763 | Taurine | NA | Nutritional supplementation | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.1985759 %) | Approved | 27742486 |
DrugRepV_2780 | BIBR 953 | NA | Hypertension | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.5344416 %) | Approved | 27742486 |
DrugRepV_2811 | Cefoselis Sulfate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.3205301 %) | NA | 27742486 |
DrugRepV_2813 | Rizatriptan Benzoate | NA | Migraine disorders | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.3908172 %) | Approved | 27742486 |
DrugRepV_2814 | 2-Thiouracil | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.4015713 %) | NA | 27742486 |
DrugRepV_2818 | Suplatast tosylate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.4609451 %) | NA | 27742486 |
DrugRepV_2831 | Xylazine Hydrochloride | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.9275587 %) | Approved, Vet Approved | 27742486 |
DrugRepV_2843 | Danofloxacin Mesylate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-6.3487008 %) | Experimental, Vet approved | 27742486 |
DrugRepV_2856 | Amidopyrine | NA | Pain | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-6.8828073 %) | NA | 27742486 |
DrugRepV_2861 | Ubenimex | NA | Acute myelocytic leukemia | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-7.1327673 %) | Approved | 27742486 |
DrugRepV_2878 | Betapar | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-8.1507562 %) | NA | 27742486 |
DrugRepV_2889 | Malotilate | NA | Liver disease | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-8.5901104 %) | NA | 27742486 |
DrugRepV_2891 | PMSF | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-8.6777643 %) | NA | 27742486 |
DrugRepV_2907 | Tranilast | NA | Bronchial asthma | Keloid and hypertrophic scar | Allergic disorders such as asthma, allergic rhinitis | Atopic dermatitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-9.5539143 %) | Investigational | 27742486 |
DrugRepV_2913 | Noradrenaline Bitartrate Monohydrate | NA | NA | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-9.8741533 %) | NA | 27742486 |
DrugRepV_2961 | Doxycycline-Ribavirin | NA | NA | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 25970853 |
DrugRepV_2964 | Doxycycline-Ribavirin | NA | NA | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Enzyme-linked immunosorbent assay | Decrease (95 %) | Approved | 25970853 |
DrugRepV_2967 | Doxycycline-Ribavirin | NA | NA | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (91 %) | Approved | 25970853 |
DrugRepV_2970 | Doxycycline-Ribavirin | NA | NA | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (92 %) | Approved | 25970853 |
DrugRepV_2973 | Doxycycline-Ribavirin | NA | NA | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (91 %) | Approved | 25970853 |
DrugRepV_2976 | Doxycycline-Ribavirin | NA | NA | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | MTT assay | Decrease (88.2 %) | Approved | 25970853 |
DrugRepV_2977 | Apigenin | NA | NA | Chikungunya virus | CHIKV replicon | NA | EGFP assay | Decrease (50 %) | Experimental | 22205980 |
DrugRepV_2979 | Naringenin | NA | NA | Chikungunya virus | CHIKV replicon | NA | EGFP assay | Decrease (50 %) | Experimental | 22205980 |
DrugRepV_2980 | Silybin | NA | NA | Chikungunya virus | CHIKV replicon | NA | EGFP assay | Decrease (50 %) | Experimental, Investigational | 22205980 |
DrugRepV_2984 | 6-Azauridine | NA | Cancer | Chikungunya virus | CHIKV replicon | NA | EGFP assay | Decrease (50 %) | NA | 22205980 |
DrugRepV_2985 | 3-NH2-3-deoxyadenosine | NA | NA | Chikungunya virus | CHIKV replicon | NA | EGFP assay | Decrease (50 %) | NA | 22205980 |
DrugRepV_2986 | Apigenin | NA | NA | Chikungunya virus | CHIKV replicon | NA | Rluc assay | Decrease (50 %) | Experimental | 22205980 |
DrugRepV_2988 | Naringenin | NA | NA | Chikungunya virus | CHIKV replicon | NA | Rluc assay | Decrease (50 %) | Experimental | 22205980 |
DrugRepV_2989 | Silybin | NA | NA | Chikungunya virus | CHIKV replicon | NA | Rluc assay | Decrease (50 %) | Experimental, Investigational | 22205980 |
DrugRepV_2993 | 6-Azauridine | NA | Cancer | Chikungunya virus | CHIKV replicon | NA | Rluc assay | Decrease (50 %) | NA | 22205980 |
DrugRepV_2994 | 3-NH2-3-deoxyadenosine | NA | NA | Chikungunya virus | CHIKV replicon | NA | Rluc assay | Decrease (50 %) | NA | 22205980 |
DrugRepV_2999 | Sulfonyl Amidine | NA | NA | Chikungunya virus | NA | NA | Plaque assay | Decrease (10 %) | NA | 25643977 |
DrugRepV_3000 | Sulfonyl Amidine | NA | NA | Chikungunya virus | NA | NA | Plaque assay | Decrease (40 %) | NA | 25643977 |
DrugRepV_3011 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Zika virus | HD78788 | NA | Plaque assay | Decrease (75 %) | Approved | 28343845 |
DrugRepV_3012 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Zika virus | HD78788 | NA | Real-time PCR | Decrease | Approved | 28343845 |
DrugRepV_3013 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Zika virus | HD78788 | NA | Real-time PCR | Decrease (0.8 log) | Approved | 28343845 |
DrugRepV_3014 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Real-time PCR | Decrease (1 log) | Approved | 28343845 |
DrugRepV_3015 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Zika virus | HD78788 | NA | Real-time PCR | Decrease (1 log) | Approved | 28343845 |
DrugRepV_3016 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Zika virus | HD78788 | NA | Real-time PCR | Decrease (1 log) | Approved | 28343845 |
DrugRepV_3017 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Real-time PCR | Decrease (0.7 log) | Approved | 28343845 |
DrugRepV_3018 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Real-time PCR | Decrease (0.8 log) | Approved | 28343845 |
DrugRepV_3019 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Real-time PCR | Decrease (0.5 log) | Approved | 28343845 |
DrugRepV_3020 | Demethoxycurcumin | NA | NA | Zika virus | HD78788 | NA | Plaque assay | Decrease | Phase II | 28343845 |
DrugRepV_3022 | EF-24 | NA | NA | Zika virus | HD78788 | NA | Plaque assay | Decrease | NA | 28343845 |
DrugRepV_3023 | FLLL31 | NA | NA | Zika virus | HD78788 | NA | Plaque assay | Decrease | NA | 28343845 |
DrugRepV_3024 | Demethoxycurcumin | NA | NA | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease | Phase II | 28343845 |
DrugRepV_3026 | EF-24 | NA | NA | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease | NA | 28343845 |
DrugRepV_3027 | FLLL31 | NA | NA | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease | NA | 28343845 |
DrugRepV_3028 | Demethoxycurcumin | NA | NA | Zika virus | HD78788 | NA | Plaque assay | Decrease (50 %) | Phase II | 28343845 |
DrugRepV_3030 | EF-24 | NA | NA | Zika virus | HD78788 | NA | Plaque assay | Decrease (50 %) | NA | 28343845 |
DrugRepV_3031 | FLLL31 | NA | NA | Zika virus | HD78788 | NA | Plaque assay | Decrease (50 %) | NA | 28343845 |
DrugRepV_3032 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Zika virus | HD78788 | NA | Plaque assay | Decrease (50 %) | Approved | 28343845 |
DrugRepV_3033 | Demethoxycurcumin | NA | NA | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease (50 %) | Phase II | 28343845 |
DrugRepV_3035 | EF-24 | NA | NA | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease (50 %) | NA | 28343845 |
DrugRepV_3036 | FLLL31 | NA | NA | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease (50 %) | NA | 28343845 |
DrugRepV_3037 | Curcumin | NA | Cancer, mucositis, chronic schizophrenia and mild cognitive impairment | Chikungunya virus | La Reunion strain, 06-049 AM258994 | NA | Plaque assay | Decrease (50 %) | Approved | 28343845 |
DrugRepV_3038 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | LR2006 OPY1 | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 26752081 |
DrugRepV_3039 | Abamectin | NA | Helmintic infection | Chikungunya virus | LR2006 OPY1 | NA | Luciferase reporter assay | Decrease (50 %) | Terminated | 26752081 |
DrugRepV_3043 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | LR2006 OPY1 | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 26752081 |
DrugRepV_3044 | Abamectin | NA | Helmintic infection | Chikungunya virus | LR2006 OPY1 | NA | Luciferase reporter assay | Decrease (50 %) | Terminated | 26752081 |
DrugRepV_3048 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (100 %) | Terminated | 26752081 |
DrugRepV_3050 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (87 %) | Approved | 26752081 |
DrugRepV_3061 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Renilla luciferase assay | No significant effect (No significant effect %) | Terminated | 26752081 |
DrugRepV_3063 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | CHIKV-Rluc | NA | Renilla luciferase assay | No significant effect (No significant effect %) | Approved | 26752081 |
DrugRepV_3066 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Northern blot | Decrease | Terminated | 26752081 |
DrugRepV_3068 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3069 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3072 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3073 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Western blot | Decrease | Terminated | 26752081 |
DrugRepV_3076 | Abamectin | NA | Helmintic infection | Chikungunya virus | CHIKV-Rluc | NA | Plaque assay | Decrease (3.5 Log) | Terminated | 26752081 |
DrugRepV_3077 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | CHIKV-Rluc | NA | Plaque assay | Decrease (5.2 Log) | Approved | 26752081 |
DrugRepV_3082 | Abamectin | NA | Helmintic infection | Chikungunya virus | NA | NA | Plaque assay | Decrease (2 Log) | Terminated | 26752081 |
DrugRepV_3083 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | NA | NA | Plaque assay | Decrease (3.3 Log) | Approved | 26752081 |
DrugRepV_3085 | Abamectin | NA | Helmintic infection | Chikungunya virus | NA | NA | Plaque assay | Decrease (0.3 Log) | Terminated | 26752081 |
DrugRepV_3086 | Berberine | NA | Parasitic and fungal infection | Chikungunya virus | NA | NA | Plaque assay | Decrease (1.2 Log) | Approved | 26752081 |
DrugRepV_3089 | Dipterocarpol | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (100 %) | NA | 23275491 |
DrugRepV_3091 | Aloe-emodin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.89 %) | NA | 23275491 |
DrugRepV_3092 | Retrorsine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.84 %) | NA | 23275491 |
DrugRepV_3094 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.76 %) | NA | 23275491 |
DrugRepV_3096 | Tunicamycin B | NA | Bacterial infections | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.7 %) | Experimental | 23275491 |
DrugRepV_3097 | Corydaline | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.69 %) | NA | 23275491 |
DrugRepV_3100 | Usnic Acid | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.54 %) | NA | 23275491 |
DrugRepV_3101 | Rhapontin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.53 %) | NA | 23275491 |
DrugRepV_3103 | Ferutinin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.43 %) | NA | 23275491 |
DrugRepV_3104 | Diacetoxyscirpenol | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.27 %) | NA | 23275491 |
DrugRepV_3107 | Acivicin | NA | Cancer | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (99.07 %) | Phase I | 23275491 |
DrugRepV_3109 | Jervine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (98.35 %) | NA | 23275491 |
DrugRepV_3110 | Hypocrellin B | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (98.08 %) | NA | 23275491 |
DrugRepV_3111 | Valinomycin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (97.79 %) | Experimental | 23275491 |
DrugRepV_3112 | Hypocrellin A | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (97.64 %) | NA | 23275491 |
DrugRepV_3114 | E-64 | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (95.94 %) | NA | 23275491 |
DrugRepV_3115 | Magnolol | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (95.74 %) | NA | 23275491 |
DrugRepV_3117 | Nonactin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (95.31 %) | NA | 23275491 |
DrugRepV_3119 | Ochratoxin A | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (94.95 %) | NA | 23275491 |
DrugRepV_3121 | Parthenolide | NA | Allergic Contact Dermatitis | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (93.95 %) | Approved, Investigational | 23275491 |
DrugRepV_3124 | Rottlerin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (92.81 %) | NA | 23275491 |
DrugRepV_3125 | Grayanotoxin III | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (91.39 %) | NA | 23275491 |
DrugRepV_3126 | Gossypol | NA | Non-small Cell Lung Cancer | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (90.89 %) | Investigational | 23275491 |
DrugRepV_3127 | Sanguinarine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (90.83 %) | NA | 23275491 |
DrugRepV_3130 | Cyclopiazonic Acid | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (79.93 %) | NA | 23275491 |
DrugRepV_3131 | Harmine Hydrochloride | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Immunoflourescence assay | Decrease (73.68 %) | NA | 23275491 |
DrugRepV_3132 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (50 %) | NA | 23275491 |
DrugRepV_3133 | Hypocrellin A | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (50 %) | NA | 23275491 |
DrugRepV_3134 | Rottlerin | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (50 %) | NA | 23275491 |
DrugRepV_3136 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Plaque assay | Decrease (4.3 Log) | NA | 23275491 |
DrugRepV_3137 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (2.3 Log) | NA | 23275491 |
DrugRepV_3140 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (3 Log) | NA | 23275491 |
DrugRepV_3141 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Plaque assay | Decrease (3.5 Log) | NA | 23275491 |
DrugRepV_3142 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (2.8 Log) | NA | 23275491 |
DrugRepV_3143 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (7.8 Log) | NA | 23275491 |
DrugRepV_3144 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Plaque assay | Decrease (6.4 Log) | NA | 23275491 |
DrugRepV_3145 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Real-time PCR | Decrease (6 (Complete inhibition) Log) | NA | 23275491 |
DrugRepV_3146 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Real-time PCR | Decrease (2 Log) | NA | 23275491 |
DrugRepV_3147 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Real-time PCR | Decrease (2 Log) | NA | 23275491 |
DrugRepV_3148 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Real-time PCR | Decrease (2.4 Log) | NA | 23275491 |
DrugRepV_3149 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Real-time PCR | Decrease (3 Log) | NA | 23275491 |
DrugRepV_3150 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3151 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3152 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3153 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-0708 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3154 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3155 | Harringtonine | NA | NA | Chikungunya virus | CHIKV-122508 | NA | Western blot | Decrease | NA | 23275491 |
DrugRepV_3157 | 6-Azauridine | NA | Cancer | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 14670584 |
DrugRepV_3160 | Fucoidan | NA | NA | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 14670584 |
DrugRepV_3165 | 6-Azauridine | NA | Cancer | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (1.8 Log) | NA | 14670584 |
DrugRepV_3169 | 6-Azauridine | NA | Cancer | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (99 %) | NA | 14670584 |
DrugRepV_3172 | IFN-alpha2b-Ribavirin | NA | NA | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 14670584 |
DrugRepV_3181 | Arbidol | NA | Viral infection | Influenza virus | A/Aichi/2/68 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3182 | Arbidol | NA | Viral infection | Influenza virus | B/Beijing/184/93 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3183 | Arbidol | NA | Viral infection | Influenza virus | A/Mem Bel | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3184 | Arbidol | NA | Viral infection | Influenza virus | A/Queensland/6/72 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3185 | Arbidol | NA | Viral infection | Influenza virus | A/Sydney/5/ 97 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3186 | Arbidol | NA | Viral infection | Influenza virus | A/Moscow/16/98 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3187 | Arbidol | NA | Viral infection | Influenza virus | A/PR/8/34 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3188 | Arbidol | NA | Viral infection | Influenza virus | A/Moscow/17/98 | | Plaque assay | Decrease (50 %) | Investigational | 22028179 |
DrugRepV_3191 | Arbidol | NA | Viral infection | Influenza virus | A/Aichi/2/68 | | Plaque assay | Decrease (Decrease (0.5-1.0) log) | Investigational | 22028179 |
DrugRepV_3194 | Arbidol | NA | Viral infection | Influenza virus | A/Aichi/2/68 | | Quantal assay | Decrease (1.5 log) | Investigational | 22028179 |
DrugRepV_3197 | Arbidol | NA | Viral infection | Influenza virus | A/Aichi/2/68 | | Plaque assay | Decrease (2.5 log) | Investigational | 22028179 |
DrugRepV_3198 | Arbidol | NA | Viral infection | Influenza virus | A/Aichi/2/68 | | Plaque assay | Decrease (3.73 log) | Investigational | 22028179 |
DrugRepV_3199 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Plaque assay | No significant effect (No significant reduction log) | Investigational | 26384169 |
DrugRepV_3200 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Flow cytometry | Decrease (90 %) | Investigational | 26384169 |
DrugRepV_3201 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (3 Log) | Investigational | 26384169 |
DrugRepV_3202 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Plaque assay | Decrease (2 Log) | Investigational | 26384169 |
DrugRepV_3203 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (50 %) | Investigational | 26384169 |
DrugRepV_3204 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Plaque assay | Decrease (50 %) | Investigational | 26384169 |
DrugRepV_3205 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (Capsid protein Protein expression) | Investigational | 26384169 |
DrugRepV_3206 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (E1 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3207 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (pE2 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3208 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (E2 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3209 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (nsP2 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3210 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Western blot | Decrease (nsP3 protein Protein expression) | Investigational | 26384169 |
DrugRepV_3211 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Real-time PCR | Decrease (2 Log) | Investigational | 26384169 |
DrugRepV_3212 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Real-time PCR | Decrease (2 Log) | Investigational | 26384169 |
DrugRepV_3213 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Cell viability assay | Decrease (25 %) | Investigational | 26384169 |
DrugRepV_3214 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Cell viability assay | Decrease (65 %) | Investigational | 26384169 |
DrugRepV_3215 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Cell viability assay | Decrease (65 %) | Investigational | 26384169 |
DrugRepV_3216 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Plaque assay | Decrease (1 Log) | Investigational | 26384169 |
DrugRepV_3217 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Plaque assay | Decrease (2 Log) | Investigational | 26384169 |
DrugRepV_3218 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VT | NA | Plaque assay | Decrease (1.8 Log) | Investigational | 26384169 |
DrugRepV_3219 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | No significant effect (No significant reduction Log) | Investigational | 26384169 |
DrugRepV_3220 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (1 Log) | Investigational | 26384169 |
DrugRepV_3221 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (0.9 Log) | Investigational | 26384169 |
DrugRepV_3222 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (No significant reduction Log) | Investigational | 26384169 |
DrugRepV_3223 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (1.2 Log) | Investigational | 26384169 |
DrugRepV_3224 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (1.2 Log) | Investigational | 26384169 |
DrugRepV_3225 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VS | NA | Western blot | Decrease (pE2 protein expression Protein expression) | Investigational | 26384169 |
DrugRepV_3226 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VS | NA | Western blot | Decrease (E2 protein expresion Protein expression) | Investigational | 26384169 |
DrugRepV_3227 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Western blot | Decrease (pE2 protein expression Protein expression) | Investigational | 26384169 |
DrugRepV_3228 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Western blot | Decrease (E2 protein expresion Protein expression) | Investigational | 26384169 |
DrugRepV_3229 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226VS | NA | Plaque assay | Decrease (1.3 Log) | Investigational | 26384169 |
DrugRepV_3230 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (2.5 Log) | Investigational | 26384169 |
DrugRepV_3231 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (2 Log) | Investigational | 26384169 |
DrugRepV_3232 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Real-time PCR | Decrease (2 Log) | Investigational | 26384169 |
DrugRepV_3233 | Andrographolide | NA | Ulcerative colitis and Upper respiratory tract infection | Chikungunya virus | E1:226AS | NA | Plaque assay | Decrease (50 %) | Investigational | 26384169 |
DrugRepV_3240 | T-1105 | NA | Zika virus | Chikungunya virus | Indian Ocean strain 899 | NA | Colorimetric method | Decrease (50 %) | NA | 24951535 |
DrugRepV_3241 | T-1105 | NA | Zika virus | Chikungunya virus | Indian Ocean strain 899 | NA | Colorimetric method | Decrease (50 %) | NA | 24951535 |
DrugRepV_3248 | T-1105 | NA | Zika virus | Chikungunya virus | Indian Ocean strain 899 | NA | Plaque assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3249 | T-1105 | NA | Zika virus | Chikungunya virus | Indian Ocean strain 899 | NA | Real-time PCR | Decrease (50 %) | NA | 24951535 |
DrugRepV_3250 | T-1105 | NA | Zika virus | Chikungunya virus | LR2006 OPY1 | NA | Real-time PCR | Decrease (50 %) | NA | 24951535 |
DrugRepV_3251 | T-1105 | NA | Zika virus | Chikungunya virus | Venturini (Italy 2008) | NA | Real-time PCR | Decrease (50 %) | NA | 24951535 |
DrugRepV_3252 | T-1105 | NA | Zika virus | Chikungunya virus | Bianchi (Italy 2008) | NA | Real-time PCR | Decrease (50 %) | NA | 24951535 |
DrugRepV_3253 | T-1105 | NA | Zika virus | Chikungunya virus | Congo 95 (2011) | NA | Real-time PCR | Decrease (50 %) | NA | 24951535 |
DrugRepV_3264 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res C1-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3265 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res C2-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3266 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res C3-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3270 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res_p7 C1-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3271 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res_p7 C2-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3272 | T-1105 | NA | Zika virus | Chikungunya virus | Favipiravir_res_p7 C3-CHIKV 899 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 24951535 |
DrugRepV_3273 | 5-Tetradecyloxy-2-furoic Acid | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3275 | Cerulenin | NA | Fungal infection | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | Approved | 27177310 |
DrugRepV_3277 | AnnH18 | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3278 | AnnH14 | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3279 | KH-CB19 | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3280 | Anacardic Acid | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3281 | TAE684 | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3284 | 6-Hydroxyflavone | NA | Anxiety-like disorders | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3287 | Alsterpaullone | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | Experimental | 27177310 |
DrugRepV_3290 | Tivozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | Investigational | 27177310 |
DrugRepV_3292 | Linifanib | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (50 %) | NA | 27177310 |
DrugRepV_3293 | 5-Tetradecyloxy-2-furoic Acid | NA | NA | Influenza virus | NA | | Flow cytometry | Decrease (100 %) | NA | 27177310 |
DrugRepV_3294 | Cerulenin | NA | Fungal infection | Influenza virus | NA | | Flow cytometry | Decrease (100 %) | Approved | 27177310 |
DrugRepV_3297 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Influenza virus | NA | | Flow cytometry | Decrease (100 %) | Investigational | 27177310 |
DrugRepV_3298 | Anacardic Acid | NA | NA | Chikungunya virus | NA | NA | Flow cytometry | Decrease (75 %) | NA | 27177310 |
DrugRepV_3300 | Cerulenin | NA | Fungal infection | Chikungunya virus | NA | NA | Flow cytometry | Decrease (75 %) | Approved | 27177310 |
DrugRepV_3302 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | NA | NA | Flow cytometry | Decrease (90 %) | Investigational | 27177310 |
DrugRepV_3303 | Cerulenin | NA | Fungal infection | Chikungunya virus | NA | NA | Real-time PCR | Decrease (100 %) | Approved | 27177310 |
DrugRepV_3304 | 5-Tetradecyloxy-2-furoic Acid | NA | NA | Chikungunya virus | NA | NA | Real-time PCR | Decrease (100 %) | NA | 27177310 |
DrugRepV_3306 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | NA | NA | Real-time PCR | Decrease (50 %) | Investigational | 27177310 |
DrugRepV_3307 | Cerulenin | NA | Fungal infection | Chikungunya virus | NA | NA | Real-time PCR | Decrease (100 %) | Approved | 27177310 |
DrugRepV_3308 | 5-Tetradecyloxy-2-furoic Acid | NA | NA | Chikungunya virus | NA | NA | Real-time PCR | Decrease (100 %) | NA | 27177310 |
DrugRepV_3310 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | NA | NA | Real-time PCR | Decrease (80 %) | Investigational | 27177310 |
DrugRepV_3311 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | C21 | NA | Survival assay | NA | Investigational | 27177310 |
DrugRepV_3312 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | C21 | NA | Plaque assay | No significant reduction (0.9 Log) | Investigational | 27177310 |
DrugRepV_3313 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | C21 | NA | Plaque assay | Decrease (1.2 Log) | Investigational | 27177310 |
DrugRepV_3314 | TIvozanib | NA | Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease | Chikungunya virus | C21 | NA | Plaque assay | No significant reduction (0.8 Log) | Investigational | 27177310 |
DrugRepV_3316 | 5-Tetradecyloxy-2-furoic Acid | NA | NA | Chikungunya virus | C21 | NA | Plaque assay | No significant reduction (0.2 Log) | NA | 27177310 |
DrugRepV_3350 | Trametinib-Oseltamivir | NA | NA | Influenza virus | WSN/H1N1 | | Plaque assay | Decrease (95 %) | Approved | 29990517 |
DrugRepV_3352 | Trametinib-Oseltamivir | NA | NA | Influenza virus | WSN/H1N1 | | Plaque assay | Decrease (3.5 Log) | Approved | 29990517 |
DrugRepV_3376 | Mycophenolic Acid-Betaferon | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | NA | 24096239 |
DrugRepV_3382 | Betaferon | NA | Multiple sclerosis | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3407 | SSYA10-001 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 24841268 |
DrugRepV_3408 | SSYA10-001 | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 24841268 |
DrugRepV_3409 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/California/07/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3413 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | B/Bris/60/2008 (Victoria) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3416 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/California/7/2009 (H1N1) | | Plaque assay | Decrease (2.1 Log) | Investigational | 28778830 |
DrugRepV_3417 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/California/7/2009 (H1N1) | | Plaque assay | Decrease (2.9 Log) | Investigational | 28778830 |
DrugRepV_3420 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/WSN/1933 (H1N1) | | Plaque assay | Decrease (1.7 Log) | Investigational | 28778830 |
DrugRepV_3422 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/DM/528/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3423 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Texas/4/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3424 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/North Carolina/39/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3425 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Washington/29/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3426 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/WSN/1933 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3427 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/California/07/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3428 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/DM/524/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3429 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Switzerland/9715293/2013 (H3N2) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3430 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Switzerland/9715293/2013 X-247 (H3N2) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3431 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Hongkong/4801/2014 (H3N2) | | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3432 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/California/2/2014 (H3N2) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3433 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Udorn/1972 (H3N2) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3434 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | A/Soloman Islands/3/2006 (H1N1) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3435 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | B/Wisconsin/1/2010 (Yamagata) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3436 | Dapivirine | NA | Acquired immunodeficiency syndrome | Influenza virus | B/Bris/60/2008 (Victoria) | | Plaque assay | Decrease (50 %) | Investigational | 28778830 |
DrugRepV_3439 | Saliphenylhalamide | NA | NA | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | NA | 22910914 |
DrugRepV_3442 | NVP-AUY922 | NA | NA | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | NA | 22910914 |
DrugRepV_3443 | Alvespimycin | NA | Cancer | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | Investigational | 22910914 |
DrugRepV_3444 | Tanespimycin | NA | Cancer | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | Investigational | 22910914 |
DrugRepV_3447 | Saliphenylhalamide | NA | NA | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | NA | 22910914 |
DrugRepV_3450 | NVP-AUY922 | NA | NA | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | NA | 22910914 |
DrugRepV_3451 | Alvespimycin | NA | Cancer | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | Investigational | 22910914 |
DrugRepV_3452 | Tanespimycin | NA | Cancer | Influenza virus | PR8-GFP | | GFP assay | Decrease (50 %) | Investigational | 22910914 |
DrugRepV_3470 | Pyrrolopyridinamine PPA-7 | NA | NA | Influenza virus | CA/09 (H1N1) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3471 | Aminothiadiazole ATD-1 | NA | NA | Influenza virus | CA/09 (H1N1) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3472 | Dihydrofuropyridine carboxamide HPC-2 | NA | NA | Influenza virus | CA/09 (H1N1) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3473 | Pyrrolopyridinamine PPA-7 | NA | NA | Influenza virus | PE/09 (H3N2) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3474 | Aminothiadiazole ATD-1 | NA | NA | Influenza virus | PE/09 (H3N2) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3475 | Dihydrofuropyridine carboxamide HPC-2 | NA | NA | Influenza virus | PE/09 (H3N2) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3476 | Pyrrolopyridinamine PPA-7 | NA | NA | Influenza virus | B/Florida/04/2006 (B/FL/06) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3477 | Aminothiadiazole ATD-1 | NA | NA | Influenza virus | B/Florida/04/2006 (B/FL/06) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3478 | Dihydrofuropyridine carboxamide HPC-2 | NA | NA | Influenza virus | B/Florida/04/2006 (B/FL/06) | | Immunoflourescence assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3479 | Pyrrolopyridinamine PPA-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3480 | Pyrrolopyridinamine PPA-2 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3481 | Pyrrolopyridinamine PPA-3 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3482 | Pyrrolopyridinamine PPA-4 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3483 | Pyrrolopyridinamine PPA-5 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3484 | Pyrrolopyridinamine PPA-6 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3485 | Pyrrolopyridinamine PPA-7 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3486 | Pyrrolopyridinamine PPA-8 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3487 | Pyrrolopyridinamine PPA-9 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3488 | Pyrrolopyridinamine PPA-10 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3489 | Pyrrolopyridinamine PPA-11 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3490 | Pyrrolopyridinamine PPA-12 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3491 | Pyrrolopyridinamine PPA-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3492 | Pyrrolopyridinamine PPA-2 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3493 | Pyrrolopyridinamine PPA-3 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3494 | Pyrrolopyridinamine PPA-4 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3495 | Pyrrolopyridinamine PPA-5 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3496 | Pyrrolopyridinamine PPA-6 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3497 | Pyrrolopyridinamine PPA-7 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3498 | Pyrrolopyridinamine PPA-8 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3499 | Pyrrolopyridinamine PPA-9 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3500 | Pyrrolopyridinamine PPA-10 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3501 | Pyrrolopyridinamine PPA-11 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3502 | Pyrrolopyridinamine PPA-12 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3503 | Aminothiadiazole ATD-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3504 | Aminothiadiazole ATD-2 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3505 | Aminothiadiazole ATD-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3506 | Aminothiadiazole ATD-2 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3507 | Dihydrofuropyridine carboxamide HPC-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3508 | Dihydrofuropyridine carboxamide HPC-2 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3509 | Dihydrofuropyridine carboxamide HPC-3 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3510 | Dihydrofuropyridine carboxamide HPC-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3511 | Dihydrofuropyridine carboxamide HPC-2 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3512 | Dihydrofuropyridine carboxamide HPC-3 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3513 | Imidazopyridinamine IPA-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3514 | Imidazopyridinamine IPA-1 | NA | NA | Influenza virus | A/Puerto Rico/8/1934 virus (NS1-GFP virus) | | PR8GFP Assay | Decrease (50 %) | NA | 27586275 |
DrugRepV_3578 | AY9944 | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3581 | GBR-12783 | NA | Psychosis | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3582 | Tabimorelin | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3584 | Camylofine | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3587 | ML9 | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3593 | Iminodyn 17 | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3594 | Nobiletin | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3596 | N-Acetyl-L-leucyl- L- leucyl-L- methional | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3597 | Calpeptin | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3599 | Gentian Violet | NA | Bacterial infection | Fungal infections (mouth (thrush) and skin) | Nipah virus | NA | NA | Taqman PCR | Decrease (50 %) | Approved | 19889218 |
DrugRepV_3600 | Gliotoxin | NA | NA | Nipah virus | NA | NA | Taqman PCR | Decrease (50 %) | NA | 19889218 |
DrugRepV_3602 | Gentian Violet | NA | Bacterial infection | Fungal infections (mouth (thrush) and skin) | Hendra virus | NA | NA | Taqman PCR | Decrease (50 %) | Approved | 19889218 |
DrugRepV_3603 | Gliotoxin | NA | NA | Hendra virus | NA | NA | Taqman PCR | Decrease (50 %) | NA | 19889218 |
DrugRepV_3605 | Gentian Violet | NA | Bacterial infection | Fungal infections (mouth (thrush) and skin) | Nipah virus | NA | NA | Taqman PCR | Decrease (50 %) | Approved | 19889218 |
DrugRepV_3606 | Gliotoxin | NA | NA | Nipah virus | NA | NA | Taqman PCR | Decrease (50 %) | NA | 19889218 |
DrugRepV_3608 | Gentian Violet | NA | Bacterial infection | Fungal infections (mouth (thrush) and skin) | Hendra virus | NA | NA | Taqman PCR | Decrease (50 %) | Approved | 19889218 |
DrugRepV_3609 | Gliotoxin | NA | NA | Hendra virus | NA | NA | Taqman PCR | Decrease (50 %) | NA | 19889218 |
DrugRepV_3610 | Gliotoxin | NA | NA | Influenza virus | A/ swine/Rachaburi/2000 (H1N1) | | Taqman PCR | Decrease (50 %) | NA | 19889218 |
DrugRepV_3611 | C-c3 Ado | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3612 | 5 Noraristeromycin | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3613 | DHCaA | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3615 | EICAR | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3616 | Pyrazofurin | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3617 | Carbodine | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3618 | 6-Azauridine | NA | Cancer | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3619 | Poly(I)-poly(C12U) | NA | NA | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3621 | 6-Azauridine | NA | Cancer | Nipah virus | NA | NA | RT-PCR | Decrease | NA | 16641448 |
DrugRepV_3627 | Cyanovirin-N | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 15073681 |
DrugRepV_3628 | Cyanovirin-N | NA | NA | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 15073681 |
DrugRepV_3629 | Cyanovirin-N | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 15073681 |
DrugRepV_3630 | N-methyl-5,7-dinitro-N-propylquinolin-8-amine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3631 | 2-[3-(4-chlorophenyl)-1-(3-methoxyphenyl)-3-oxopropyl]propanedinitrile | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3632 | (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,9,15(20)-pentaene-14,18-dione | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3633 | 2-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3634 | N-(3,4-dichlorophenyl)-5-nitrofuran-2-carboxamide | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3635 | 7-[(furan-2-yl)methyl]-3-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-imine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3636 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3637 | N,N-bis(4-methylphenyl)pyridin-3-amine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3638 | N-methyl-5,7-dinitro-N-propylquinolin-8-amine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3639 | 2-[3-(4-chlorophenyl)-1-(3-methoxyphenyl)-3-oxopropyl]propanedinitrile | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3640 | (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,9,15(20)-pentaene-14,18-dione | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3641 | 2-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3642 | N-(3,4-dichlorophenyl)-5-nitrofuran-2-carboxamide | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3643 | 7-[(furan-2-yl)methyl]-3-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-imine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3644 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3645 | N,N-bis(4-methylphenyl)pyridin-3-amine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3646 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3647 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3648 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Rift Valley fever virus | MP12 | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3649 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Influenza virus | California/07/2009 | | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3650 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Influenza virus | Brisbane/10/2007 | | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3651 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3652 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3653 | 2-methyl-4-phenyl-1H-naphtho[2,3-b][1,4]diazepine hydrochloride | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3654 | 2-(4-chlorophenyl)-7,8-dimethyl-4-(trifluoromethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3655 | 2-(1,1,2,2,2-pentafluoroethyl)-4-phenyl-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3656 | 7,8-dichloro-2-(1,1,2,2,2-pentafluoroethyl)-4-phenyl-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3657 | 2-[4-(trifluoromethyl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3658 | 2-(4-methylphenyl)-4-(trifluoromethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3659 | 4-methoxy-2-[4-(trifluoromethyl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3660 | 2-[4-(thiophen-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3661 | 4-chloro-2-[4-(furan-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3662 | 4-methoxy-2-[4-(thiophen-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3663 | 2-[4-(furan-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3664 | 2-[4-(3-nitrophenyl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3665 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3666 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3667 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (100 %) | NA | 21270170 |
DrugRepV_3668 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (98 %) | NA | 21270170 |
DrugRepV_3669 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Lassa virus | NA | NA | Luciferase reporter assay | Decrease (40 %) | NA | 21270170 |
DrugRepV_3670 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Influenza virus | Goose/Qinghai/59/05 | | Luciferase reporter assay | Decrease (15 %) | NA | 21270170 |
DrugRepV_3671 | 2,6-bis[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenol | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (100 %) | NA | 22027648 |
DrugRepV_3672 | NSC 62914 | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease | NA | 22027648 |
DrugRepV_3673 | NSC 62914 | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 22027648 |
DrugRepV_3674 | Trolox | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (45 %) | NA | 22027648 |
DrugRepV_3675 | Trolox | NA | NA | Marburg virus | NA | NA | RT-PCR | Decrease (70 %) | NA | 22027648 |
DrugRepV_3676 | NSC 62914 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (98 %) | NA | 22027648 |
DrugRepV_3677 | NSC 62914 | NA | NA | Lassa virus | Josiah | NA | RT-PCR | Decrease (98 %) | NA | 22027648 |
DrugRepV_3678 | NSC 62914 | NA | NA | Rift Valley fever virus | MP12 | NA | RT-PCR | Decrease (97 %) | NA | 22027648 |
DrugRepV_3679 | NSC 62914 | NA | NA | Ebola virus | NA | NA | NA | Decrease | NA | 22027648 |
DrugRepV_3680 | NSC 62914 | NA | NA | Marburg virus | NA | NA | NA | Decrease | NA | 22027648 |
DrugRepV_3681 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine tetrahydrochloride | NA | NA | Ebola virus | Zaire-95 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3682 | N5,N14-bis[2-(morpholin-4-yl)ethyl]-3,12-bis({[2-(morpholin-4-yl)ethyl]amino})-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-5,14-dicarboxamide; hexakis(trifluoroacet | NA | NA | Ebola virus | Zaire-95 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3683 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine | NA | NA | Ebola virus | Zaire-95 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3684 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine tetrahydrochloride | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3685 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3686 | BCX4430 | NA | Ebola virus | Marburg virus | Musoke | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3687 | BCX4430 | NA | Ebola virus | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3688 | BCX4430 | NA | Ebola virus | Marburg virus | Angola | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3689 | BCX4430 | NA | Ebola virus | Ebola virus | Kikwit | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3690 | BCX4430 | NA | Ebola virus | Chikungunya virus | AF 15561 | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3691 | BCX4430 | NA | Ebola virus | Rift Valley fever virus | ZH5018 | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3692 | BCX4430 | NA | Ebola virus | Lassa virus | Josiah | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3693 | BCX4430 | NA | Ebola virus | Nipah virus | Malaysia | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3694 | BCX4430 | NA | Ebola virus | Middle East respiratory syndrome coronavirus | Jordan N3 | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3695 | BCX4430 | NA | Ebola virus | Severe acute respiratory syndrome coronavirus | Urbani | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3696 | BCX4430 | NA | Ebola virus | Influenza virus | pH1N1 | | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3698 | 6-Azauridine | NA | Cancer | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 24713118 |
DrugRepV_3699 | 2-C-Methylcytidine | NA | Hepatitis C virus | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | Experimental | 24713118 |
DrugRepV_3701 | 6-Azauridine | NA | Cancer | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 24713118 |
DrugRepV_3702 | 2-C-Methylcytidine | NA | Hepatitis C virus | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Experimental | 24713118 |
DrugRepV_3704 | 6-Azauridine | NA | Cancer | Marburg virus | NA | NA | NA | Decrease (98 %) | NA | 24713118 |
DrugRepV_3708 | 6-Azauridine | NA | Cancer | Ebola virus | NA | NA | NA | Decrease (99 %) | NA | 24713118 |
DrugRepV_3711 | C795-0925 | NA | NA | Rift Valley fever virus | ZH548/MP-12 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3712 | D011-2120 | NA | NA | Rift Valley fever virus | ZH548/MP-12 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3713 | F694-1532 | NA | NA | Rift Valley fever virus | ZH548/MP-12 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3714 | G202-0362 | NA | NA | Rift Valley fever virus | ZH548/MP-12 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3715 | C795-0925 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3716 | D011-2120 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3717 | F694-1532 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3718 | G202-0362 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3719 | C795-0925 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3720 | D011-2120 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3721 | F694-1532 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3722 | G202-0362 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3723 | C795-0925 | NA | NA | Lassa virus | Josiah | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3724 | D011-2120 | NA | NA | Lassa virus | Josiah | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3725 | F694-1532 | NA | NA | Lassa virus | Josiah | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3727 | AZD8055 | NA | Cancer | Lassa virus | NA | NA | NA | Decrease | Investigational | 25986249 |
DrugRepV_3728 | TWS119 | NA | NA | Lassa virus | NA | NA | NA | Decrease | NA | 25986249 |
DrugRepV_3729 | SU 4312 | NA | NA | Lassa virus | NA | NA | NA | Decrease | NA | 25986249 |
DrugRepV_3730 | Falnidamol dihydrochloride | NA | Solid Tumor | Lassa virus | NA | NA | NA | Decrease | Investigational | 25986249 |
DrugRepV_3731 | Ki 8751 | NA | NA | Lassa virus | NA | NA | NA | Decrease | NA | 25986249 |
DrugRepV_3732 | 10-DEBC hydrochloride | NA | NA | Lassa virus | NA | NA | NA | Decrease | NA | 25986249 |
DrugRepV_3738 | Falnidamol dihydrochloride | NA | Solid Tumor | Lassa virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3739 | Falnidamol dihydrochloride | NA | Solid Tumor | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3740 | Falnidamol dihydrochloride | NA | Solid Tumor | Marburg virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3742 | Falnidamol | NA | Solid Tumor | Lassa virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3744 | Falnidamol | NA | Solid Tumor | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3745 | Falnidamol | NA | Solid Tumor | Ebola virus | 1976 | NA | Firefly luciferase assay | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3746 | Falnidamol | NA | Solid Tumor | Ebola virus | 2014 | NA | Firefly luciferase assay | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3747 | Falnidamol | NA | Solid Tumor | Lassa virus | NA | NA | Firefly luciferase assay | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3751 | MLS000078751 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3752 | MLS000394177 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3753 | MLS000534476 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3754 | MLS000554255 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3755 | MLS000555232 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3756 | MLS000730532 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3757 | MLS000733230 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3758 | MLS000762907 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3759 | MLS001101371 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3760 | MLS000078751 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3761 | MLS000394177 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3762 | MLS000534476 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3763 | MLS000554255 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3764 | MLS000555232 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3765 | MLS000730532 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3766 | MLS000733230 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3767 | MLS000762907 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3768 | MLS001101371 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3769 | MLS001239325 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3770 | MLS001239325 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3771 | MLS001030162 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3772 | MLS001030162 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3773 | MLS000666802 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3774 | MLS000666802 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3775 | MLS000999960 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3776 | MLS000999960 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3777 | MLS001173370 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3778 | MLS001173370 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3779 | MLS001174896 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3780 | MLS001174896 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3781 | MLS001196083 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3782 | MLS001196083 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3783 | MLS001239358 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3784 | MLS001239358 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3785 | MLS001177927 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3786 | MLS001177927 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3787 | MLS001209453 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3788 | MLS001209453 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3789 | MLS000580080 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3790 | MLS000580080 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3791 | MLS000106706 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3792 | MLS000106706 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3793 | MLS001175455 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3794 | MLS001175455 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3795 | MLS000772389 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3796 | MLS000772389 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3797 | MLS000042810 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3798 | MLS000042810 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3799 | MLS001162808 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3800 | MLS001162808 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3801 | MLS000684231 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3802 | MLS000684231 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3803 | MLS000556387 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3804 | MLS000556387 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3805 | MLS001179278 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3806 | MLS001179278 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3807 | MLS000567464 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3808 | MLS000567464 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3809 | MLS000583959 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3810 | MLS000583959 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3811 | MLS001018888 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3812 | MLS001018888 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3813 | MLS001047402 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3814 | MLS001047402 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3815 | MLS001029946 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3816 | MLS001029946 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3817 | MLS000332573 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3818 | MLS000332573 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3819 | MLS000936259 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3820 | MLS000936259 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3821 | MLS000718690 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3822 | MLS000718690 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3823 | MLS000880330 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3824 | MLS000880330 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3825 | MLS001207131 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3826 | MLS001207131 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3827 | MLS000673118 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3828 | MLS000673118 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3829 | MLS000689481 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3830 | MLS000689481 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3831 | MLS001179272 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3832 | MLS001179272 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3833 | MLS002702500 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3834 | MLS002702500 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3835 | MLS001180408 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3836 | MLS000737975 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3837 | MLS001237534 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3838 | MLS000336293 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3839 | MLS000780111 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3840 | MLS001179997 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3841 | MLS000418057 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3842 | MLS000936795 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3843 | MLS000092187 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3844 | MLS000391391 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3845 | MLS000569139 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3846 | MLS001045935 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3847 | MLS001181479 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3848 | MLS000391984 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3849 | MLS000063146 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3850 | MLS000768081 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3851 | MLS000091920 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3852 | MLS001150589 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3853 | MLS000736237 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3855 | Enclomiphene | NA | Male hypogonadism | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | Investigational | 27490565 |
DrugRepV_3856 | Zuclomiphene | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27490565 |
DrugRepV_3858 | Enclomiphene | NA | Male hypogonadism | Ebola virus | Mayinga | NA | Renilla luciferase assay | Decrease (100 %) | Investigational | 27490565 |
DrugRepV_3859 | Zuclomiphene | NA | NA | Ebola virus | Mayinga | NA | Renilla luciferase assay | Decrease (100 %) | NA | 27490565 |
DrugRepV_3867 | BCX4430 | NA | Ebola virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3868 | BCX4430 | NA | Ebola virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3869 | BCX4430 | NA | Ebola virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3870 | BCX4430 | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3871 | BCX4430 | NA | Ebola virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3872 | BCX4430 | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3873 | BCX4430 | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3874 | BCX4430 | NA | Ebola virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 27838352 |
DrugRepV_3883 | UV-1 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3884 | UV-2 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3885 | UV-3 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3886 | UV-4 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3887 | UV-5 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3888 | UV-1 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3889 | UV-2 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3890 | UV-3 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3891 | UV-4 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3892 | UV-5 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3893 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3894 | cp15 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3895 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3896 | cp15 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3897 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3898 | cp19 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3899 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3900 | cp19 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3901 | cp3 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3902 | cp5 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3903 | cp11 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3904 | cp13 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3905 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3906 | cp16 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3907 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3908 | cp3 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3909 | cp5 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3910 | cp11 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3911 | cp13 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3912 | cp15 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3913 | cp16 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3914 | cp19 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3915 | cp3 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3916 | cp5 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3917 | cp11 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3918 | cp13 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3919 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3920 | cp16 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3921 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3922 | CBS1129 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3923 | CBS1130 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3924 | CBS1131 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3925 | CBS1132 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3926 | CBS1133 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3927 | CBS1134 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3928 | CBS1135 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3929 | CBS1136 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3930 | CBS1137 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3931 | CBS1138 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3932 | CBS1139 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3933 | IHVR-19029 | NA | NA | Zika virus | PRVABC-59 | NA | qRT-PCR | Decrease (50 %) | NA | 29253498 |
DrugRepV_3934 | IHVR-19029 | NA | NA | Ebola virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 29253498 |
DrugRepV_3938 | GSK983 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3939 | Angelicin | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3940 | Benzoquinoline | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3941 | SW539 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3942 | SW320 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3943 | SW351 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3944 | SW491 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3945 | SW490 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3946 | SW388 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3947 | SW386 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3948 | SW349 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3949 | SW991 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3950 | SW456 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3953 | 12N-p-dichlorobenzyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3954 | 12N-o-methylbenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3955 | 12N-2,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3956 | 12N-3,5 -dichlorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3957 | 12N-3,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3958 | 12N-m-methoxybenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3959 | 12N-benzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3960 | 12N-p-trifluoromethoxylbenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3961 | 12N-p-fluorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3962 | 12N-3,5-dichlorobenzoyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3963 | 12N-p-chlorobenzoyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3964 | 12N-3,4-dichlorobenzoyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3965 | 12N-3,4-dichlorobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3966 | 12N-3,5-dichlorobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3967 | 12N-o-thiophenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3968 | 12N-m-cyanobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3969 | 12N-p-chlorobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3970 | 12N-p-chlorophenylethyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3971 | 12N-3,4-dichlorophenylethyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3972 | 12N-3,5-dichlorophenylethyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3973 | 12N-3,4-dichlorohydrocinnamyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3974 | 12N-3,5-dichlorohydrocinnamyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3975 | 12N-p-chlorohydrocinnamyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3976 | 12N-p-dichlorobenzyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3977 | 12N-o-methylbenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3978 | 12N-2,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3979 | 12N-3,5 -dichlorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3980 | 12N-3,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3981 | 12N-m-methoxybenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3982 | 12N-benzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3983 | 12N-p-trifluoromethoxylbenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3984 | 12N-p-fluorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3985 | 12N-3,5-dichlorobenzoyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3986 | 12N-p-chlorobenzoyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3987 | 12N-3,4-dichlorobenzoyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3988 | 12N-3,4-dichlorobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3989 | 12N-3,5-dichlorobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3990 | 12N-o-thiophenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3991 | 12N-m-cyanobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3992 | 12N-p-chlorobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3996 | Tyrphostin AG1478 | NA | NA | Lassa virus | NA | NA | Luciferase assay | Decrease (100 %) | NA | 21947546 |
DrugRepV_3997 | Tyrphostin AG1478 | NA | NA | Marburg virus | NA | NA | Luciferase assay | Decrease (100 %) | NA | 21947546 |
DrugRepV_3998 | Tyrphostin AG1478 | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (100 %) | NA | 21947546 |
DrugRepV_3999 | Genistein-Tyrphostin AG1478 | NA | NA | Lassa virus | NA | NA | Luciferase assay | Decrease (99 %) | NA | 21947546 |
DrugRepV_4000 | Genistein-Tyrphostin AG1478 | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (99 %) | NA | 21947546 |
DrugRepV_4001 | FGI-103 | NA | NA | Ebola virus | Zaire | NA | Plaque assay | Decrease (50 %) | NA | 20211898 |
DrugRepV_4002 | FGI-103 | NA | NA | Ebola virus | Sudan | NA | Plaque assay | Decrease (50 %) | NA | 20211898 |
DrugRepV_4003 | FGI-103 | NA | NA | Marburg virus | Ravn | NA | Plaque assay | Decrease (50 %) | NA | 20211898 |
DrugRepV_4004 | FGI-103 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (95 %) | NA | 20211898 |
DrugRepV_4005 | FGI-103 | NA | NA | Ebola virus | Zaire | NA | NA | Decrease | NA | 20211898 |
DrugRepV_4006 | 2-APB | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4007 | A23187 | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4008 | Di-Tert-Butylhydroquinone | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4009 | CA1001 | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4011 | Ionomycin | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4012 | Ryanodine | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4013 | Thapsigargin | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4014 | Xestospongin C | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4015 | 2-APB | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4016 | A23187 | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4017 | Di-Tert-Butylhydroquinone | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4018 | CA1001 | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4020 | Ionomycin | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4021 | Ryanodine | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4022 | Thapsigargin | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4023 | Xestospongin C | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4024 | Agatoxin | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4026 | Conotoxin | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Investigational | 20668647 |
DrugRepV_4028 | Lanthanum Chloride | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4032 | Tetrandrine | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Experimental | 20668647 |
DrugRepV_4034 | 5-N-ethyl isopropyl amiloride | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4036 | Benzamil | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4039 | Agatoxin | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4041 | Conotoxin | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Investigational | 20668647 |
DrugRepV_4043 | Lanthanum Chloride | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4047 | Tetrandrine | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Experimental | 20668647 |
DrugRepV_4049 | 5-N-ethyl isopropyl amiloride | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4051 | Benzamil | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4054 | 7-octyl-indolactam | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4056 | Gliotoxin | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4057 | Oleic Acid | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved, Investigational, Vet approved | 20668647 |
DrugRepV_4059 | PKC Inhibitor | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4060 | PMA | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4061 | Rottlerin | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4062 | U73122 | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4063 | 7-octyl-indolactam | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4065 | Gliotoxin | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4066 | Oleic Acid | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved, Investigational, Vet approved | 20668647 |
DrugRepV_4068 | PKC Inhibitor | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4069 | PMA | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4070 | Rottlerin | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4071 | U73122 | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 20668647 |
DrugRepV_4072 | 25-OH-cholecalciferol | NA | NA | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved, Nutraceutical | 20668647 |
DrugRepV_4073 | 4-OH-tamoxifen | NA | Breast cancer | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Investigational | 20668647 |
DrugRepV_4074 | Arg-vasopressin | NA | Enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved | 20668647 |
DrugRepV_4075 | Bradykinin | NA | Hypertension and Diabetes Type 2 | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Investigational | 20668647 |
DrugRepV_4077 | Cholecalciferol | NA | Vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia | Hendra virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved | 20668647 |
DrugRepV_4080 | 25-OH-cholecalciferol | NA | NA | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved, Nutraceutical | 20668647 |
DrugRepV_4081 | 4-OH-tamoxifen | NA | Breast cancer | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Investigational | 20668647 |
DrugRepV_4082 | Arg-vasopressin | NA | Enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved | 20668647 |
DrugRepV_4083 | Bradykinin | NA | Hypertension and Diabetes Type 3 | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Investigational | 20668647 |
DrugRepV_4085 | Cholecalciferol | NA | Vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia | Nipah virus | NA | NA | Immunolabeling assay | Decrease (50 %) | Approved | 20668647 |
DrugRepV_4103 | 2-(4-tert-butylphenyl)-N-[(E)-(3,4-diethoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4104 | 2-(4-tert-butylphenyl)-N-[(E)-(3,5-dibromo-4-methoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4105 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4106 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(trifluoromethyl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4107 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(methylsulfanyl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4108 | 2-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4109 | 2-(4-tert-butylphenyl)-N-[(1E)-2-[(1-methylnaphthalen-2-yl)oxy]ethylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4110 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(propan-2-yl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4111 | 2-(4-tert-butylphenyl)-N-[(1E)-1-phenylpropylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4112 | N-[(E)-(4-bromophenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4113 | N-[(E)-(4-hydroxyphenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4114 | N-[(E)-(4-cyclohexylphenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4115 | N-[(1E)-1-(4-methoxyphenyl)ethylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4116 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(3,4-diethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | NA | NA | CPE reduction assay | Decrease (50 %) | NA | 23380636 |
DrugRepV_4117 | Coumarin A | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (50 %) | NA | 28100218 |
DrugRepV_4118 | Coumarin B | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (50 %) | NA | 28100218 |
DrugRepV_4119 | Lupeol Acetate 26SK001 | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (50 %) | NA | 28100218 |
DrugRepV_4120 | Voacangine 26SK002 | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (50 %) | NA | 28100218 |
DrugRepV_4121 | Coumarin A | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (44 %) | NA | 28100218 |
DrugRepV_4122 | Coumarin B | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (92.5 %) | NA | 28100218 |
DrugRepV_4123 | Lupeol Acetate 26SK001 | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (4.1 %) | NA | 28100218 |
DrugRepV_4124 | Voacangine 26SK002 | NA | NA | Chikungunya virus | Acol | NA | Plating method | Decrease (0.4 %) | NA | 28100218 |
DrugRepV_4125 | 3-{3-[(1E)-1-(hydroxyimino)ethyl]phenyl}-5-methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4126 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-methyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4127 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4128 | 3-(3-acetylphenyl)-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4129 | 5-(aminomethyl)-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4130 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-sulfanyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4131 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-(methylsulfanyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4132 | 3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-5-(methylamino)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4133 | 5-ethyl-3-{3-[(1E)-1-{[2-(4-methylpiperazin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4134 | 5-ethyl-3-{3-[(1E)-1-{[2-(morpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4135 | 5-ethyl-3-{3-[(1E)-1-{[2-(thiomorpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4136 | 3-{3-[(1E)-1-{[2-(diethylamino)ethoxy]imino}ethyl]phenyl}-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4137 | 3-{3-[(1E)-1-{[2-(cyclohexylamino)ethoxy]imino}ethyl]phenyl}-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4138 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4139 | 5-ethyl-3-{3-[(1E)-1-{[2-(pyrrolidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4140 | 3-{3-[(1E)-1-({2-[4-(dimethylamino)piperidin-1-yl]ethoxy}imino)ethyl]phenyl}-5-ethyl-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | 899 | NA | CPE inhibition assay | Decrease (50 %) | NA | 28619679 |
DrugRepV_4141 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Venturini | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4142 | 5-ethyl-3-{3-[(1E)-1-{[2-(morpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Venturini | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4143 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Venturini | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4144 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Congo 95 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4145 | 5-ethyl-3-{3-[(1E)-1-{[2-(morpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Congo 95 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4146 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Congo 95 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4147 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | St. Martin 20235 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4148 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | St. Martin 20235 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4149 | 2-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4150 | 2-(4-tert-butylphenyl)-N-[(E)-[4-(trifluoromethyl)phenyl]methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4151 | N-[(E)-(4-hydroxyphenyl)methylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4152 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4153 | N-[(1E)-1-(4-methoxyphenyl)ethylidene]-2-phenylcyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4154 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(3,4-diethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4155 | 2-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4156 | 2-(4-tert-butylphenyl)-N-[(E)-(4-hydroxyphenyl)methylidene]cyclopropane-1-carbohydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4157 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4158 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4159 | (2E)-3-(4-methylphenyl)-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4160 | (2E)-N-[(E)-(4-methylphenyl)methylidene]-3-phenylprop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4161 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-[4-(propan-2-yl)phenyl]methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4162 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-tert-butylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4163 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4164 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-phenylprop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4165 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-phenylmethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4166 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-nitrophenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4167 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(4-chlorophenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4168 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(pyrazin-2-yl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4169 | (2E)-3-(4-tert-butylphenyl)-N-[(1E)-1-(4-ethoxyphenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4170 | (2E)-N-[(1E)-1-{[1,1-biphenyl]-4-yl}ethylidene]-3-(4-tert-butylphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4171 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-(4-methylphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4172 | (2E)-3-(4-tert-butylphenyl)-N-{[4-(trifluoromethyl)phenyl]methyl}prop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4173 | (2E)-3-phenyl-N-{[4-(trifluoromethyl)phenyl]methyl}prop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4174 | (2E)-N-({[1,1-biphenyl]-4-yl}methyl)-3-(4-tert-butylphenyl)prop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4175 | (2E)-N-({[1,1-biphenyl]-4-yl}methyl)-3-phenylprop-2-enamide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4176 | 3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4177 | N-[(E)-(4-ethoxyphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4178 | 3-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4179 | N-[(E)-(4-methylphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4180 | 3-(4-tert-butylphenyl)-N-[(E)-(4-hydroxyphenyl)methylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4181 | N-[(E)-(4-methylphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4182 | 3-(4-tert-butylphenyl)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]propanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4183 | N-[(E)-(4-cyclohexylphenyl)methylidene]-3-phenylpropanehydrazide | NA | NA | Chikungunya virus | 889 | NA | CPE reduction assay | Decrease (50 %) | NA | 29336951 |
DrugRepV_4184 | 1-(4-{2-[1-cyclohexyl-2-(furan-3-yl)-1H-1,3-benzodiazol-5-yl]-1,3-oxazol-5-yl}phenyl)pyrrolidin-2-one | NA | NA | Chikungunya virus | SL10571 | NA | MTT assay | Decrease (50 %) | NA | 28236746 |
DrugRepV_4186 | 1-(4-{2-[1-cyclohexyl-2-(furan-3-yl)-1H-1,3-benzodiazol-5-yl]-1,3-oxazol-5-yl}phenyl)pyrrolidin-2-one | NA | NA | Chikungunya virus | S27 | NA | MTT assay | Decrease (50 %) | NA | 28236746 |
DrugRepV_4188 | 1-(4-{2-[1-cyclohexyl-2-(furan-3-yl)-1H-1,3-benzodiazol-5-yl]-1,3-oxazol-5-yl}phenyl)pyrrolidin-2-one | NA | NA | Chikungunya virus | BaH306 | NA | MTT assay | Decrease (50 %) | NA | 28236746 |
DrugRepV_4190 | Phorbol | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4191 | Phorbol-12-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 25970561 |
DrugRepV_4192 | Phorbol-12-decanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4193 | Phorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4194 | Phorbol-13-butyrate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4195 | Pphorbol-13-decanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4196 | Phorbol-13-tetradecanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4197 | Phorbol-12,13-diacetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4198 | Phorbol-12,13-dibutyrate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4199 | Phorbol-12,13- dihexanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4200 | Phorbol-12,13-didecanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4201 | 4α-phorbol-12,13-didecanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4202 | 12-O-tetradecanoylphorbol-13-acetate | NA | Cancer | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Phase II | 25970561 |
DrugRepV_4203 | 12-O-tetradecanoyl-4?-phorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4204 | 12-O- tiglylphorbol-13-decanoate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4205 | 12-O-(N-methylanthranilate) phorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4206 | Phorbol-13,20-diacetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4207 | 12,13-O,O-dinonanoylphorbol-20-homovanillate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4208 | 12-O-phenylacetyl-13-O-acetylphorbol-20-homovanillate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4209 | Phorbol-12,13,20-triacetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4210 | 20-oxo-20-deoxyphorbol-12,13-dibutyrate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4211 | 12-O-tetradecanoyl-20-oxo-20-deoxyphorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4212 | 12-deoxyphorbol-13-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4213 | 13-O-isobutyryl-12-deoxyphorbol-20-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4214 | 13-O-phenylacetyl-12-deoxyphorbol-20-acetate | NA | NA | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_4218 | Resiniferatoxin | NA | Interstitial cystitis and urinary incontinence | Chikungunya virus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 25970561 |
DrugRepV_4220 | Arbidol | NA | NA | Chikungunya virus | LR2006 OPY1 | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 21440006 |
DrugRepV_4221 | HZ2a | NA | NA | Chikungunya virus | LR2006 OPY1 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 21440006 |
DrugRepV_4222 | 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(phe- nylsulphonylmethyl)-1H-indole-3-carboxylate | NA | NA | Chikungunya virus | LR2006 OPY1 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 21440006 |
DrugRepV_4223 | 6-bromo- 4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(methylphenyl- sulphoxyde)-1H-indole-3-carboxylate | NA | NA | Chikungunya virus | LR2006 OPY1 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 21440006 |
DrugRepV_4224 | (2E)-3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4225 | 3-[(E)-{[2-(4-methylphenyl)-1H-indol-3-yl]methylidene}amino]-1-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4226 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4227 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-[4-(trifluoromethyl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4228 | (2E)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-(4-methoxyphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4229 | (2E)-3-{[1,1-biphenyl]-4-yl}-N-[(E)-(4-ethoxyphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4230 | (2E)-N-[(E)-(4-methylphenyl)methylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4231 | (2E)-N-[(E)-(4-methylphenyl)methylidene]-3-[4-(trifluoromethyl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4232 | (2E)-3-(4-methoxyphenyl)-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4233 | (2E)-3-{[1,1-biphenyl]-4-yl}-N-[(E)-(4-methylphenyl)methylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4234 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4235 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-[4-(trifluoromethyl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4236 | (2E)-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-3-(4-methoxyphenyl)prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4237 | (2E)-3-{[1,1-biphenyl]-4-yl}-N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4238 | (2E)-N-[(E)-(4-hydroxyphenyl)methylidene]-3-[4-(propan-2-yl)phenyl]prop-2-enehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4239 | N-[(E)-(4-ethoxyphenyl)methylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4240 | N-[(E)-(4-ethoxyphenyl)methylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4241 | N-[(E)-(4-ethoxyphenyl)methylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4242 | N-[(E)-(4-ethoxyphenyl)methylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4243 | N-[(E)-(4-ethoxyphenyl)methylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4244 | N-[(E)-(4-methylphenyl)methylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4245 | N-[(E)-(4-methylphenyl)methylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4246 | N-[(E)-(4-methylphenyl)methylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4247 | N-[(E)-(4-methylphenyl)methylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4248 | N-[(E)-(4-methylphenyl)methylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4249 | N-[(E)-(4-hydroxyphenyl)methylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4250 | N-[(E)-(4-hydroxyphenyl)methylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4251 | N-[(E)-(4-hydroxyphenyl)methylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4252 | N-[(E)-(4-hydroxyphenyl)methylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4253 | N-[(E)-(4-hydroxyphenyl)methylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4254 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]naphthalene-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4255 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]quinoline-3-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4256 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]quinoline-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4257 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-1H-indole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4258 | N-[(1E)-1-(4-cyclohexylphenyl)ethylidene]-1H-1,3-benzodiazole-2-carbohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4259 | 3-(4-tert-butylphenyl)-N-[(E)-(4-ethoxyphenyl)methylidene]-3-oxopropanehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4260 | 3-(4-tert-butylphenyl)-N-[(E)-(4-methylphenyl)methylidene]-3-oxopropanehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4261 | 3-(4-tert-butylphenyl)-N-[(E)-(4-hydroxyphenyl)methylidene]-3-oxopropanehydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4262 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[(4-ethoxyphenyl)methylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4263 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[(4-methylphenyl)methylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4264 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[(4-hydroxyphenyl)methylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4265 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(E)-[1-(4-cyclohexylphenyl)ethylidene]amino]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4266 | 1-[(E)-[(4-ethoxyphenyl)methylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4267 | 1-[(E)-[(4-methylphenyl)methylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4268 | 1-[(E)-[(4-hydroxyphenyl)methylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4269 | 1-[(E)-[1-(4-cyclohexylphenyl)ethylidene]amino]-3-(2-phenylethyl)thiourea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4270 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(4-ethoxyphenyl)methyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4271 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-[(4-methylphenyl)methyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4272 | 1-benzyl-3-[(1E)-2-(4-tert-butylphenyl)ethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4273 | 1-[(4-methoxyphenyl)methyl]-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4274 | 1-[(4-methylphenyl)methyl]-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4275 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-(4-methylphenyl)urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4276 | 3-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-(4-hydroxyphenyl)urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4277 | 1-(4-methylphenyl)-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4278 | 1-(4-hydroxyphenyl)-3-[(1E)-2-phenylethenyl]urea | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4279 | N-[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]-4-ethoxybenzohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4280 | N-[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]-4-methylbenzohydrazide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4281 | 2-[(1E)-2-(4-tert-butylphenyl)ethenyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4282 | 2-[(1E)-2-(4-tert-butylphenyl)ethenyl]-5-(4-methylphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4283 | 2-[2-(4-tert-butylphenyl)ethyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4284 | 2-[2-(4-tert-butylphenyl)ethyl]-5-(4-methylphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4285 | 2-(4-ethoxyphenyl)-5-(2-phenylethyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4286 | 2-(4-methylphenyl)-5-(2-phenylethyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4287 | 4-{5-[2-(4-tert-butylphenyl)ethyl]-1,3,4-oxadiazol-2-yl}phenol | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4288 | 2-[(4-tert-butylphenyl)methyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4289 | 2-[(4-tert-butylphenyl)methyl]-5-(4-methylphenyl)-1,3,4-oxadiazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4290 | 4-(4-methylphenyl)-1-(2-phenylethyl)-1H-1,2,3-triazole | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4291 | (2E)-3-(4-tert-butylphenyl)-N-(5-methyl-1H-1,3-benzodiazol-2-yl)prop-2-enamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4292 | (2E)-N-(1H-1,3-benzodiazol-2-yl)-3-(4-tert-butylphenyl)prop-2-enamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4293 | 3-(4-tert-butylphenyl)-N-(5-methyl-1H-1,3-benzodiazol-2-yl)propanamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4294 | N-(1H-1,3-benzodiazol-2-yl)-3-(4-tert-butylphenyl)propanamide | NA | NA | Chikungunya virus | 899 | NA | CPE reduction assay | Decrease (50 %) | NA | 29499487 |
DrugRepV_4299 | Fisetin | NA | Frail Elderly Syndrome | Chikungunya virus | NA | NA | NA | Decrease (50 %) | Experimental | 27460167 |
DrugRepV_4300 | Quercetagetin | NA | NA | Chikungunya virus | NA | NA | NA | Decrease (50 %) | NA | 27460167 |
DrugRepV_4302 | Carbocyclic adenosine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4303 | Carbocyclic 3-deazaadenosine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4304 | 9-[trans- 2,trans - 3 - dihydroxy - 4 - (methyl) - cyclopent - 4 - enyl] - 3 - deazaadenine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4305 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-adenine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4306 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-3-deazaadenine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4307 | 9-[trans-2,trans-3-dihydroxycyclopent-4-enyl]- adenine (DHCpAdo) | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4308 | 9-[trans-2,trans-3-dihydroxycyclopent- 4-enyl]-3-deazaadenine (DHCp-c3Ado) | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4309 | 4,5- didehydro-5-deoxy-5-fluoroadenosine (DDFA) | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4311 | Guanosine Dialdehyde | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4312 | Adenosine Dialdehyde | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | Approved, Investigational | 9988190 |
DrugRepV_4314 | Carbocyclic 3-deazaadenosine | NA | NA | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4315 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-adenine | NA | NA | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4316 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-3-deazaadenine | NA | NA | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4317 | Carbocyclic 3-deazaadenosine | NA | NA | Ebola virus | EBO-Z | NA | Survival assay | Increase | NA | 9988190 |
DrugRepV_4318 | FGI-106 | NA | NA | Ebola virus | Zaire | NA | Plaque assay | Decrease (50 %) | NA | 19523489 |
DrugRepV_4319 | FGI-106 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (50 %) | NA | 19523489 |
DrugRepV_4320 | FGI-106 | NA | NA | Ebola virus | Zaire | NA | Survival assay | Increase | NA | 19523489 |
DrugRepV_4321 | N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (44.6 %) | NA | 24501399 |
DrugRepV_4322 | N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (32.6 %) | NA | 24501399 |
DrugRepV_4323 | 9H-carbazol-3-amine | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (6.1 %) | NA | 24501399 |
DrugRepV_4324 | 7-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-3.8 %) | NA | 24501399 |
DrugRepV_4325 | N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-16 %) | NA | 24501399 |
DrugRepV_4326 | tris[4-(dimethylamino)phenyl]methanol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (31.8 %) | NA | 24501399 |
DrugRepV_4327 | 6-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (31.8 %) | NA | 24501399 |
DrugRepV_4328 | 1-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-1.6 %) | NA | 24501399 |
DrugRepV_4329 | 2-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-1.8 %) | NA | 24501399 |
DrugRepV_4330 | N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (66.3 %) | NA | 24501399 |
DrugRepV_4331 | 4-{[(5-methyl-2-thienyl)methyl]amino}phenol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-12.6 %) | NA | 24501399 |
DrugRepV_4332 | N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-3.4 %) | NA | 24501399 |
DrugRepV_4333 | N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.2 %) | NA | 24501399 |
DrugRepV_4334 | 2-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (8.6 %) | NA | 24501399 |
DrugRepV_4335 | N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (66.9 %) | NA | 24501399 |
DrugRepV_4336 | N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (9.6 %) | NA | 24501399 |
DrugRepV_4337 | 4-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (34 %) | NA | 24501399 |
DrugRepV_4338 | N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (11.6 %) | NA | 24501399 |
DrugRepV_4339 | N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (45.7 %) | NA | 24501399 |
DrugRepV_4340 | N-(3-chlorophenyl)-N-(4-cyanophenyl)urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.1 %) | NA | 24501399 |
DrugRepV_4341 | N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-3.4 %) | NA | 24501399 |
DrugRepV_4342 | N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (5.7 %) | NA | 24501399 |
DrugRepV_4343 | 4,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-24.6 %) | NA | 24501399 |
DrugRepV_4344 | 1-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (13.1 %) | NA | 24501399 |
DrugRepV_4345 | 2-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (6.4 %) | NA | 24501399 |
DrugRepV_4346 | N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (6.2 %) | NA | 24501399 |
DrugRepV_4347 | 2-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.7 %) | NA | 24501399 |
DrugRepV_4348 | N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (2.1 %) | NA | 24501399 |
DrugRepV_4349 | 4,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-0.6 %) | NA | 24501399 |
DrugRepV_4350 | N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-2.6 %) | NA | 24501399 |
DrugRepV_4351 | 3-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-6.1 %) | NA | 24501399 |
DrugRepV_4352 | methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (82.4 %) | NA | 24501399 |
DrugRepV_4353 | N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (33.4 %) | NA | 24501399 |
DrugRepV_4354 | N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (25.4 %) | NA | 24501399 |
DrugRepV_4355 | (1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.5 %) | NA | 24501399 |
DrugRepV_4356 | 4-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (25.2 %) | NA | 24501399 |
DrugRepV_4357 | N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (17.4 %) | NA | 24501399 |
DrugRepV_4358 | 3-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (26.8 %) | NA | 24501399 |
DrugRepV_4359 | 5-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-6.6 %) | NA | 24501399 |
DrugRepV_4360 | 6-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (20.9 %) | NA | 24501399 |
DrugRepV_4361 | 2-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-12.1 %) | NA | 24501399 |
DrugRepV_4362 | N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (12.3 %) | NA | 24501399 |
DrugRepV_4363 | 4-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (1.8 %) | NA | 24501399 |
DrugRepV_4364 | 2-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (1.1 %) | NA | 24501399 |
DrugRepV_4365 | 5-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-0.3 %) | NA | 24501399 |
DrugRepV_4366 | 2-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-1.5 %) | NA | 24501399 |
DrugRepV_4367 | 2-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-15.9 %) | NA | 24501399 |
DrugRepV_4368 | N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-11.5 %) | NA | 24501399 |
DrugRepV_4369 | 8-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-11.7 %) | NA | 24501399 |
DrugRepV_4370 | N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (8.05 %) | NA | 24501399 |
DrugRepV_4371 | N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (24.79 %) | NA | 24501399 |
DrugRepV_4372 | N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (31.07 %) | NA | 24501399 |
DrugRepV_4373 | 9H-carbazol-3-amine | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (8.2 %) | NA | 24501399 |
DrugRepV_4374 | 7-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (37.87 %) | NA | 24501399 |
DrugRepV_4375 | N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-0.67 %) | NA | 24501399 |
DrugRepV_4376 | tris[4-(dimethylamino)phenyl]methanol | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (108.4 %) | NA | 24501399 |
DrugRepV_4377 | 6-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (39.17 %) | NA | 24501399 |
DrugRepV_4378 | 1-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (5.24 %) | NA | 24501399 |
DrugRepV_4379 | 2-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-2.7 %) | NA | 24501399 |
DrugRepV_4380 | N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (40.4 %) | NA | 24501399 |
DrugRepV_4381 | 4-{[(5-methyl-2-thienyl)methyl]amino}phenol | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-14.4 %) | NA | 24501399 |
DrugRepV_4382 | N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-7.77 %) | NA | 24501399 |
DrugRepV_4383 | N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (0.34 %) | NA | 24501399 |
DrugRepV_4384 | 2-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-9.26 %) | NA | 24501399 |
DrugRepV_4385 | N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (73.49 %) | NA | 24501399 |
DrugRepV_4386 | N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-4.08 %) | NA | 24501399 |
DrugRepV_4387 | 4-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (7.92 %) | NA | 24501399 |
DrugRepV_4388 | N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (42.12 %) | NA | 24501399 |
DrugRepV_4389 | N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (32.88 %) | NA | 24501399 |
DrugRepV_4390 | N-(3-chlorophenyl)-N-(4-cyanophenyl)urea | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (24.49 %) | NA | 24501399 |
DrugRepV_4391 | N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (0.86 %) | NA | 24501399 |
DrugRepV_4392 | N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (6.5 %) | NA | 24501399 |
DrugRepV_4393 | 4,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-7.5 %) | NA | 24501399 |
DrugRepV_4394 | 1-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (35.73 %) | NA | 24501399 |
DrugRepV_4395 | 2-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-2.85 %) | NA | 24501399 |
DrugRepV_4396 | N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (37.33 %) | NA | 24501399 |
DrugRepV_4397 | 2-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (22.44 %) | NA | 24501399 |
DrugRepV_4398 | N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (37.22 %) | NA | 24501399 |
DrugRepV_4399 | 4,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (33.41 %) | NA | 24501399 |
DrugRepV_4400 | N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (7.38 %) | NA | 24501399 |
DrugRepV_4401 | 3-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-0.01 %) | NA | 24501399 |
DrugRepV_4402 | methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (90.92 %) | NA | 24501399 |
DrugRepV_4403 | N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (12.1 %) | NA | 24501399 |
DrugRepV_4404 | N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (21.93 %) | NA | 24501399 |
DrugRepV_4405 | (1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-8.72 %) | NA | 24501399 |
DrugRepV_4406 | 4-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (17.7 %) | NA | 24501399 |
DrugRepV_4407 | N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (23.22 %) | NA | 24501399 |
DrugRepV_4408 | 3-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (23.55 %) | NA | 24501399 |
DrugRepV_4409 | 5-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (3.55 %) | NA | 24501399 |
DrugRepV_4410 | 6-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (32.65 %) | NA | 24501399 |
DrugRepV_4411 | 2-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (3.23 %) | NA | 24501399 |
DrugRepV_4412 | N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (25.12 %) | NA | 24501399 |
DrugRepV_4413 | 4-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-11.51 %) | NA | 24501399 |
DrugRepV_4414 | 2-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (5.7 %) | NA | 24501399 |
DrugRepV_4415 | 5-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-10.47 %) | NA | 24501399 |
DrugRepV_4416 | 2-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-2.95 %) | NA | 24501399 |
DrugRepV_4417 | 2-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-9.09 %) | NA | 24501399 |
DrugRepV_4418 | N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-0.72 %) | NA | 24501399 |
DrugRepV_4419 | 8-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (-10.37 %) | NA | 24501399 |
DrugRepV_4420 | N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide | NA | NA | Hendra virus | F0, amino acids 105 to 114 | NA | CatL-Peptide cleavage | Decrease (3.26 %) | NA | 24501399 |
DrugRepV_4421 | N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (91.98 %) | NA | 24501399 |
DrugRepV_4422 | N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (98.65 %) | NA | 24501399 |
DrugRepV_4423 | 9H-carbazol-3-amine | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (42.29 %) | NA | 24501399 |
DrugRepV_4424 | 7-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (60.65 %) | NA | 24501399 |
DrugRepV_4425 | N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (-0.15 %) | NA | 24501399 |
DrugRepV_4426 | tris[4-(dimethylamino)phenyl]methanol | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (82.15 %) | NA | 24501399 |
DrugRepV_4427 | 6-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (88.99 %) | NA | 24501399 |
DrugRepV_4428 | 1-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (24.06 %) | NA | 24501399 |
DrugRepV_4429 | 2-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (57.39 %) | NA | 24501399 |
DrugRepV_4430 | N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (77.83 %) | NA | 24501399 |
DrugRepV_4431 | 4-{[(5-methyl-2-thienyl)methyl]amino}phenol | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (1.34 %) | NA | 24501399 |
DrugRepV_4432 | N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (76.53 %) | NA | 24501399 |
DrugRepV_4433 | N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (14.51 %) | NA | 24501399 |
DrugRepV_4434 | 2-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (8.55 %) | NA | 24501399 |
DrugRepV_4435 | N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (79.93 %) | NA | 24501399 |
DrugRepV_4436 | N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (69.24 %) | NA | 24501399 |
DrugRepV_4437 | 4-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (65.51 %) | NA | 24501399 |
DrugRepV_4438 | N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (80.76 %) | NA | 24501399 |
DrugRepV_4439 | N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (65.73 %) | NA | 24501399 |
DrugRepV_4440 | N-(3-chlorophenyl)-N-(4-cyanophenyl)urea | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (78.34 %) | NA | 24501399 |
DrugRepV_4441 | N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (52.46 %) | NA | 24501399 |
DrugRepV_4442 | N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (24.34 %) | NA | 24501399 |
DrugRepV_4443 | 4,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (39.61 %) | NA | 24501399 |
DrugRepV_4444 | 1-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (44.31 %) | NA | 24501399 |
DrugRepV_4445 | 2-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (38.88 %) | NA | 24501399 |
DrugRepV_4446 | N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (38.54 %) | NA | 24501399 |
DrugRepV_4447 | 2-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (50.22 %) | NA | 24501399 |
DrugRepV_4448 | N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (51.28 %) | NA | 24501399 |
DrugRepV_4449 | 4,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (39.55 %) | NA | 24501399 |
DrugRepV_4450 | N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (33.84 %) | NA | 24501399 |
DrugRepV_4451 | 3-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (23.55 %) | NA | 24501399 |
DrugRepV_4452 | methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (77.79 %) | NA | 24501399 |
DrugRepV_4453 | N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (56.45 %) | NA | 24501399 |
DrugRepV_4454 | N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (47.55 %) | NA | 24501399 |
DrugRepV_4455 | (1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (-3.09 %) | NA | 24501399 |
DrugRepV_4456 | 4-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (72.37 %) | NA | 24501399 |
DrugRepV_4457 | N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (47.94 %) | NA | 24501399 |
DrugRepV_4458 | 3-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (53.23 %) | NA | 24501399 |
DrugRepV_4459 | 5-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (28.07 %) | NA | 24501399 |
DrugRepV_4460 | 6-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (25.6 %) | NA | 24501399 |
DrugRepV_4461 | 2-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (37.16 %) | NA | 24501399 |
DrugRepV_4462 | N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (61.47 %) | NA | 24501399 |
DrugRepV_4463 | 4-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (66.62 %) | NA | 24501399 |
DrugRepV_4464 | 2-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (32.44 %) | NA | 24501399 |
DrugRepV_4465 | 5-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (30.53 %) | NA | 24501399 |
DrugRepV_4466 | 2-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (47.39 %) | NA | 24501399 |
DrugRepV_4467 | 2-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (49.81 %) | NA | 24501399 |
DrugRepV_4468 | N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (51.17 %) | NA | 24501399 |
DrugRepV_4469 | 8-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (41.66 %) | NA | 24501399 |
DrugRepV_4470 | N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | S, amino acids 674 to 683 | NA | CatL-Peptide cleavage | Decrease (40.85 %) | NA | 24501399 |
DrugRepV_4486 | Brincidofovir | NA | Viral infections | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4487 | CMX029 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4488 | CMX021 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4489 | CMX028 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4490 | CMX16669 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4491 | CMX16663 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4492 | CMX167 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4493 | CMX157 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4494 | CMX101 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4495 | CMX004 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4496 | CMX16689 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4500 | (1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4501 | (1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4502 | (1S,2R,5R)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4503 | (1R,2S,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4504 | (1R,2S,5R)-3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4505 | (1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4506 | (1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4507 | (1S,2R,5R)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4508 | (1R,2S,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4509 | (1R,2S,5R)-3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4510 | (1S,2R,5S)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4511 | (1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Influenza virus | NA | | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4519 | Alferon | NA | Condylomata acuminata | Severe acute respiratory syndrome coronavirus | NA | NA | Plaque reduction assay | Decrease (50 %) | Approved | 15200845 |
DrugRepV_4525 | IFN-alphan3 | NA | Condylomata acuminata | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (100 %) | Approved, Investigational | 15200845 |
DrugRepV_4540 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-1,2,4-triazole-3-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_4541 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-imidazole-4-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_4542 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-1,2,3-triazole-4-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_4543 | Alferon | NA | Condylomata acuminata | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Approved | 16451078 |
DrugRepV_4547 | Aurintricarboxylic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 15961169 |
DrugRepV_4548 | DS5000 | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 15961169 |
DrugRepV_4549 | Novaron | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 15961169 |
DrugRepV_4551 | S-Nitroso-N-acetylpenicillamine | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 15961169 |
DrugRepV_4552 | 7-(benzyloxy)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4553 | 2-(3,4-dihydroxyphenyl)-7-[(2-fluorophenyl)methoxy]-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4554 | 7-[(2-chlorophenyl)methoxy]-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4555 | 7-[(2-bromophenyl)methoxy]-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4556 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(2-iodophenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4557 | 2-({[2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4-oxo-4H-chromen-7-yl]oxy}methyl)benzonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4558 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(2-nitrophenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4559 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(2-methylphenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4560 | 2-(3,4-dihydroxyphenyl)-7-[(3-fluorophenyl)methoxy]-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4561 | 7-[(3-chlorophenyl)methoxy]-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4562 | 7-[(3-bromophenyl)methoxy]-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4563 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-iodophenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4564 | 3-({[2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4-oxo-4H-chromen-7-yl]oxy}methyl)benzonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4565 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-nitrophenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4566 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-methylphenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4567 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-methoxyphenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4568 | 2-(3,4-dihydroxyphenyl)-7-[(4-fluorophenyl)methoxy]-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4569 | 7-[(4-chlorophenyl)methoxy]-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4570 | 7-[(4-bromophenyl)methoxy]-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4571 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(4-iodophenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4572 | 4-({[2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-4-oxo-4H-chromen-7-yl]oxy}methyl)benzonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4573 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(4-nitrophenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4574 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(4-methylphenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4575 | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(4-methoxyphenyl)methoxy]-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 22297745 |
DrugRepV_4577 | Glycyrrhetinic Acid | NA | Apparent mineralocorticoid excess syndrome | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 15715493 |
DrugRepV_4578 | (2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4579 | (2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3-[(6-{[2-(benzylsulfanyl)-1-carboxyethyl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4580 | (2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}methyl)carbamoyl]-3-({3,4,5-trihydroxy-6-[({[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}methyl)carbamoyl]oxan-2-yl}oxy)oxan-2-yl}oxy)-2,4a,6a,6b,9,9,12a-heptame | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4581 | 6-{[(3S,6aR,6bS,8aS,11S,14bS)-4,4,6a,6b,8a,11,14b-heptamethyl-11-{[(2S)-4-methyl-1-oxopentan-2-yl]carbamoyl}-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-3,4-dihydroxy-N-[(2S)-4-methyl-1-oxopentan-2-yl]-5-[(3 | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4582 | butyl (2S)-2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-1-butoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}-3-[(6-{[(2S)-1-butoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13 | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4583 | methyl (2S)-2-(2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[({[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}methyl)carbamoyl]-3-({3,4,5-trihydroxy-6-[({[(2S)-1-methoxy-3-methyl-1-oxobutan-2-yl]carbamoyl}methyl)carbamoyl]oxan-2-yl}oxy)oxan | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4584 | (4S)-4-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-4-carboxy-1-oxobutan-2-yl]carbamoyl}-3-[(6-{[(2S)-4-carboxy-1-oxobutan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4585 | butyl (2S)-2-{[(2S,4aS,6aS,6bR,10S,12aS)-10-[(6-{[(2S)-1-butoxy-1-oxopropan-2-yl]carbamoyl}-3-[(6-{[(2S)-1-butoxy-1-oxopropan-2-yl]carbamoyl}-3,4,5-trihydroxyoxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl)oxy]-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a, | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4586 | (2S,4aS,6aS,6bR,10S,12aS)-10-{[4,5-dihydroxy-6-(2-hydroxyacetyl)-3-{[3,4,5-trihydroxy-6-(2-hydroxyacetyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carbo | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4587 | (2S,4aS,6aS,6bR,10S,12aS)-10-({4,5-dihydroxy-6-[(6-oxo-2-sulfanylidene-1,2,3,6-tetrahydropyrimidin-4-yl)carbamoyl]-3-({3,4,5-trihydroxy-6-[(6-oxo-2-sulfanylidene-1,2,3,6-tetrahydropyrimidin-4-yl)carbamoyl]oxan-2-yl}oxy)oxan-2-yl}oxy)-2,4a,6a,6b,9,9,1 | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4588 | 5-{6-[(2-{[(3S,6aR,6bS,8aS,11S,14bS)-11-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-6-(2,4-dioxo-1,2,3,4-tetrahydropyrimidi | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4589 | methyl (2S,4aS,6aS,6bR,10S,12aS)-10-({6-[(hydrazinecarbonyl)carbonyl]-3-({6-[(hydrazinecarbonyl)carbonyl]-3,4,5-trihydroxyoxan-2-yl}oxy)-4,5-dihydroxyoxan-2-yl}oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b, | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4590 | methyl (2S,4aS,6aS,6bR,10S,12aS)-10-{[6-(2-azidoacetyl)-3-{[6-(2-azidoacetyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-ca | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4591 | 2-{[(6aR,6bS,8aS,11S,14bS)-11-(acetyloxy)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4592 | 4-{[(6aR,6bS,8aS,11S,14bS)-11-(acetyloxy)-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-oxobutanoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | FFM1 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 15715493 |
DrugRepV_4593 | 3-(benzyloxy)-7-[(3-chlorophenyl)methoxy]-8-hydroxy-1,4-dihydronaphthalen-1-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4594 | 3-[(2-chlorophenyl)methoxy]-7-[(3-chlorophenyl)methoxy]-8-hydroxy-1,4-dihydronaphthalen-1-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4595 | 3,7-bis[(3-chlorophenyl)methoxy]-8-hydroxy-1,4-dihydronaphthalen-1-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4596 | 7-[(3-chlorophenyl)methoxy]-3-[(2,4-dichlorophenyl)methoxy]-8-hydroxy-1,4-dihydronaphthalen-1-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4597 | 7-[(3-chlorophenyl)methoxy]-8-hydroxy-3-[(2-iodophenyl)methoxy]-1,4-dihydronaphthalen-1-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4598 | 7-[(3-chlorophenyl)methoxy]-8-hydroxy-3-[(3-iodophenyl)methoxy]-1,4-dihydronaphthalen-1-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4599 | 2-[({6-[(3-chlorophenyl)methoxy]-5-hydroxy-4-oxo-1,4-dihydronaphthalen-2-yl}oxy)methyl]benzonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4600 | (2Z)-4-(3-{[(4-chlorophenyl)methyl]amino}phenyl)-2-hydroxy-4-oxobut-2-enoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4601 | 5,7-dihydroxy-3-[(3-nitrophenyl)methoxy]-2-phenyl-4H-chromen-4-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4602 | 3-{[(3,5-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy]methyl}benzonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21925774 |
DrugRepV_4603 | 1H-1,2,3-benzotriazol-1-yl 1H-indole-5-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4604 | 5-chloropyridin-3-yl 1H-indole-5-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4605 | 5-chloropyridin-3-yl 1-acetyl-1H-indole-5-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4606 | 5-chloropyridin-3-yl 1-(4-methylbenzenesulfonyl)-1H-indole-5-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4607 | 5-chloropyridin-3-yl 1-(3-nitrobenzenesulfonyl)-1H-indole-5-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4608 | 5-chloropyridin-3-yl1H-indole-6-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4609 | 5-chloropyridin-3-yl 1H-indole-4-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4610 | 5-chloropyridin-3-yl 1-acetyl-1H-indole-4-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4611 | 5-chloropyridin-3-yl 1H-indole-7-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4612 | 5-chloropyridin-3-yl (6R)-6-{[(tert-butoxy)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4613 | 5-chloropyridin-3-yl 2-acetyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | NA | Decrease (50 %) | NA | 18796354 |
DrugRepV_4618 | Calpain VI inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4619 | Calpain VI inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4620 | Calpain IV inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4621 | Calpain IV inhibitor | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4624 | Ampligen | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4625 | Ampligen | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4626 | UDA | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4627 | UDA | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4628 | EP128533 | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4629 | EP128533 | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 19853271 |
DrugRepV_4631 | Ampligen | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Survival assay | Increase | NA | 19853271 |
DrugRepV_4632 | UDA | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Survival assay | Increase | NA | 19853271 |
DrugRepV_4633 | Cremaphor | NA | NA | Severe acute respiratory syndrome coronavirus | v2163 | NA | Survival assay | No significant effect | NA | 19853271 |
DrugRepV_4634 | TG-0205221 | NA | SARS coronavirus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4635 | ethyl (2E,4S)-4-[(2S)-3-(4-fluorophenyl)-2-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)formamido]butanamido]propanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4636 | ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-3-phenylpropanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4637 | ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4638 | ethyl (2E,4S)-4-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(tert-butoxy)butanamido]-4-methylpentanamido]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16884309 |
DrugRepV_4639 | TG-0205221 | NA | SARS coronavirus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (6.4 Log10) | NA | 16884309 |
DrugRepV_4640 | TG-0205221 | NA | SARS coronavirus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease | NA | 16884309 |
DrugRepV_4641 | 5CI-IS-AC | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4642 | SPIII-5H | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4643 | SPIII-5Cl | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4644 | SPIII-5Br | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4645 | SPIII-5F | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4646 | SPIII-5Me | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4647 | SPIII-NA | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 20390088 |
DrugRepV_4654 | 6-Azauridine | NA | Cancer | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4657 | Kitasamycin | NA | Bacterial infections | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | Experimental | 27909576 |
DrugRepV_4658 | SAM002589981 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4659 | SAM002564206 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4660 | SAM002564189 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4661 | SAM002554886 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4662 | SAM002548975 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4663 | SAM002548938 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4664 | SAM002264636 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4665 | SAM001247107 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4666 | SAM001247103 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4667 | SAM001247083 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4668 | SAM001247075 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4669 | SAM001247056 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4670 | SAM001247054 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4671 | SAM001247052 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4672 | SAM001247038 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4673 | SAM001246989 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4674 | SAM001246979 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4675 | SAM001246977 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4676 | SAM001246883 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4677 | SAM001246690 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4678 | SAM001246644 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4679 | SAM001246622 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4680 | SAM001246545 | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27909576 |
DrugRepV_4681 | N-(4-hydroxyphenyl) retinamide | NA | NA | Zika virus | MR766 | NA | Plaque assay | Decrease (90 %) | Investigational | 29051080 |
DrugRepV_4682 | Arbidol | NA | Viral infection | Zika virus | MR766 | NA | NA | Decrease (50 %) | Investigational | 29895962 |
DrugRepV_4684 | 2-C-Methylcytidine | NA | Hepatitis C virus | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Experimental | 30061280 |
DrugRepV_4685 | 2-C-Methyladenosine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4686 | 2-C-Methylguanosine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4687 | 2-C-Methyluridine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4689 | 5-Fluoro-2-deoxyuridine | NA | Cancer | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Approved | 30061280 |
DrugRepV_4690 | 5-Fluorouridine | NA | Cancer | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Experimental | 30061280 |
DrugRepV_4691 | 5-Fluorocytidine | NA | Breast Cancer | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Phase IV | 30061280 |
DrugRepV_4693 | 2-O-Methylcytidine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4694 | 3-Deoxyadenosine | NA | Leukemia | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Investigational | 30061280 |
DrugRepV_4695 | 3-Deoxycytidine | NA | Cancer | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Phase I | 30061280 |
DrugRepV_4696 | 3-O-Methylguanosine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4697 | 3-O-Methyluridine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4698 | 9-(beta-D-Arabinofuranosyl)guanine | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4699 | 2-C-Methylcytidine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4700 | 2-C-Methyluridine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4701 | 2-C-Methyladenosine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4702 | 3-Deoxyadenosine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4703 | 5-Fluorocytidine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4704 | 3-O-Methyluridine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4705 | 2-O-Methylcytidine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4706 | 3-Deoxycytidine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4707 | 3-Deoxy-3-fluoroguanosine ProTide | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4708 | 2,4-dichloro-6-(3,4-dibromo-5-fluoro-1H-pyrrole-2-carbonyl)phenol | NA | NA | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | NA | 30061280 |
DrugRepV_4710 | 2,4-dichloro-6-(3,4-dibromo-5-fluoro-1H-pyrrole-2-carbonyl)phenol | NA | NA | Zika virus | NA | NA | Immunoflourescence assay | Decrease | NA | 30061280 |
DrugRepV_4711 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Zika virus | MR766 | NA | Plaque assay | Decrease (50 %) | Investigational | 27889529 |
DrugRepV_4713 | GSK369796 | NA | NA | Zika virus | MR766 | NA | Plaque assay | Decrease (50 %) | NA | 27889529 |
DrugRepV_4714 | Nutlin-3 | NA | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_4724 | Methotrimeprazine Maleate Salt | NA | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 29795047 |
DrugRepV_4725 | N1-(4-pyridyl)-2-chloro-5-nitrobenzamide | NA | NA | Middle East respiratory syndrome coronavirus | EMC/2012 strain | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 29795047 |
DrugRepV_4729 | L-NAME | NA | Hypotension | Spinal Cord Injury | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (15 %) | Investigational | 25487801 |
DrugRepV_4730 | AG490 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (17 %) | NA | 25487801 |
DrugRepV_4731 | PKC-412 | NA | Acute myeloid leukemia | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (33 %) | Approved, Investigational | 25487801 |
DrugRepV_4732 | Ro 31-8220 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (73 %) | NA | 25487801 |
DrugRepV_4733 | GF109203X | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (53 %) | NA | 25487801 |
DrugRepV_4734 | SB203580 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (45 %) | NA | 25487801 |
DrugRepV_4735 | U0126 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 25487801 |
DrugRepV_4736 | Wortmannin | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (40 %) | Experimental | 25487801 |
DrugRepV_4738 | Bay 11-7082 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (28 %) | NA | 25487801 |
DrugRepV_4739 | GW5074 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 25487801 |
DrugRepV_4740 | PP2 | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (23 %) | NA | 25487801 |
DrugRepV_4747 | tert-butyl 4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4748 | sodium (2S)-2-[(2S)-2-{[({1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4749 | 1-methanesulfonylpiperidin-4-yl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4750 | sodium (2S)-1-hydroxy-2-[(2S)-2-({[(1-methanesulfonylpiperidin-4-yl)oxy]carbonyl}amino)-4-methylpentanamido]-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4751 | tert-butyl 4-benzyl-4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4752 | sodium (2S)-2-[(2S)-2-{[({4-benzyl-1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4753 | 4-benzyl-1-methanesulfonylpiperidin-4-yl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4754 | sodium (2S)-2-[(2S)-2-({[(4-benzyl-1-methanesulfonylpiperidin-4-yl)oxy]carbonyl}amino)-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4755 | tert-butyl 4-ethyl-4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4756 | sodium (2S)-2-[(2S)-2-{[({1-[(tert-butoxy)carbonyl]-4-ethylpiperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4757 | ethyl 4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4758 | sodium (2S)-2-[(2S)-2-[({[1-(ethoxycarbonyl)piperidin-4-yl]oxy}carbonyl)amino]-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4759 | tert-butyl 4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4760 | sodium (2S)-2-[(2S)-2-{[({1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4761 | 1-methanesulfonylpiperidin-4-yl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4762 | sodium (2S)-1-hydroxy-2-[(2S)-2-({[(1-methanesulfonylpiperidin-4-yl)oxy]carbonyl}amino)-4-methylpentanamido]-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4763 | tert-butyl 4-benzyl-4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4764 | sodium (2S)-2-[(2S)-2-{[({4-benzyl-1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4765 | 4-benzyl-1-methanesulfonylpiperidin-4-yl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4766 | sodium (2S)-2-[(2S)-2-({[(4-benzyl-1-methanesulfonylpiperidin-4-yl)oxy]carbonyl}amino)-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4767 | tert-butyl 4-ethyl-4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4768 | sodium (2S)-2-[(2S)-2-{[({1-[(tert-butoxy)carbonyl]-4-ethylpiperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4769 | ethyl 4-({[(1S)-3-methyl-1-{[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl}butyl]carbamoyl}oxy)piperidine-1-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4770 | sodium (2S)-2-[(2S)-2-[({[1-(ethoxycarbonyl)piperidin-4-yl]oxy}carbonyl)amino]-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | FRET protease assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4771 | sodium (2S)-2-[(2S)-2-{[({1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4772 | sodium (2S)-2-[(2S)-2-{[({4-benzyl-1-[(tert-butoxy)carbonyl]piperidin-4-yl}oxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29544147 |
DrugRepV_4775 | N-ethylmaleimide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Experimental | 25542975 |
DrugRepV_4782 | IFN-universal | NA | NA | Middle East respiratory syndrome coronavirus | Hu/Jordan-N3/2012 | NA | Virus yield reduction assay | Decrease (50 %) | NA | 24323636 |
DrugRepV_4784 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4785 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4786 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4787 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4788 | 4-chloro-2-(5-{[(4Z)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4789 | 4-chloro-2-(5-{[(4Z)-5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4790 | 4-chloro-2-(5-{[(4Z)-1-(4-fluorophenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4791 | 4-chloro-2-(5-{[(4Z)-5-oxo-3-phenyl-1-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4792 | 2-(5-{[(4Z)-1-(4-tert-butylphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4793 | (4Z)-1,3-diphenyl-4-[(5-phenylfuran-2-yl)methylidene]-4,5-dihydro-1H-pyrazol-5-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4794 | 3-[(4Z)-5-oxo-3-phenyl-4-[(5-phenylfuran-2-yl)methylidene]-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4795 | 3-[(4Z)-3-methyl-5-oxo-4-[(5-phenylfuran-2-yl)methylidene]-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4796 | 2-(5-{[(4Z)-5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4797 | 2-(5-{[(4Z)-1-(4-fluorophenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4798 | 2-(5-{[(4Z)-5-oxo-3-phenyl-1-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4799 | 2-(5-{[(4Z)-1-(4-tert-butylphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4800 | 2-(5-{[(4Z)-1-(4-cyanophenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4801 | 2-(5-{[(4Z)-1-(4-methoxyphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoicacid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4802 | 3-[(4Z)-4-[(furan-2-yl)methylidene]-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4803 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4804 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4805 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4806 | 2-(5-{[(4Z)-1-(3-carboxyphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4807 | 4-chloro-2-(5-{[(4Z)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4808 | 4-chloro-2-(5-{[(4Z)-5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4809 | 4-chloro-2-(5-{[(4Z)-1-(4-fluorophenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4810 | 4-chloro-2-(5-{[(4Z)-5-oxo-3-phenyl-1-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4811 | 2-(5-{[(4Z)-1-(4-tert-butylphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)-4-chlorobenzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4812 | (4Z)-1,3-diphenyl-4-[(5-phenylfuran-2-yl)methylidene]-4,5-dihydro-1H-pyrazol-5-one | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4813 | 3-[(4Z)-5-oxo-3-phenyl-4-[(5-phenylfuran-2-yl)methylidene]-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4814 | 3-[(4Z)-3-methyl-5-oxo-4-[(5-phenylfuran-2-yl)methylidene]-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4815 | 2-(5-{[(4Z)-5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4816 | 2-(5-{[(4Z)-1-(4-fluorophenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4817 | 2-(5-{[(4Z)-5-oxo-3-phenyl-1-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4818 | 2-(5-{[(4Z)-1-(4-tert-butylphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4819 | 2-(5-{[(4Z)-1-(4-cyanophenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4820 | 2-(5-{[(4Z)-1-(4-methoxyphenyl)-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene]methyl}furan-2-yl)benzoicacid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4821 | 3-[(4Z)-4-[(furan-2-yl)methylidene]-5-oxo-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 27240464 |
DrugRepV_4828 | CTSL inhibitor | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 26953343 |
DrugRepV_4833 | 8-(trifluoromethyl)-9H-purin-6-amine | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 25746232 |
DrugRepV_4834 | 8-(trifluoromethyl)-9H-purin-6-amine | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 25746232 |
DrugRepV_4835 | 5-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 25746232 |
DrugRepV_4836 | 2-methyl-5-[(methylamino)methyl]-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 25746232 |
DrugRepV_4837 | N-[(2H-1,3-benzodioxol-5-yl)methyl]-1-[(1R)-1-(naphthalen-1-yl)ethyl]piperidine-4-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 25746232 |
DrugRepV_4838 | N-[(2H-1,3-benzodioxol-5-yl)methyl]-1-[(1S)-1-(naphthalen-1-yl)ethyl]piperidine-4-carboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 25746232 |
DrugRepV_4839 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}thiophene-2-carboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4840 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}benzamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4841 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}cyclobutanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4842 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}cyclohexanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4843 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-[4-(pyridin-4-yl)phenyl]-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4844 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}-2-methylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4845 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-[4-(2-methoxypyridin-3-yl)phenyl]-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4846 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}cyclopropanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4847 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-[4-(2-methoxypyrimidin-5-yl)phenyl]-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4848 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}-2,2,2-trifluoroacetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4849 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-[4-(pyridin-3-yl)phenyl]-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4850 | 2-methylpropyl N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}carbamate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4851 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4852 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}-2-methoxyacetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4853 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}-3-methoxypropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4854 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-[4-(methylamino)phenyl]-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4855 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-[4-(benzylamino)phenyl]-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4856 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}-2,2-dimethylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4857 | 2-methyl-N-(4-{N-[(thiophen-3-yl)methyl]-2-(1H-1,2,3-triazol-1-yl)acetamido}phenyl)propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4858 | methyl 2-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}-1H-pyrrole-1-carboxylate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (31 %) | NA | 26190463 |
DrugRepV_4859 | 2-(1H-1,2,3-benzotriazol-1-yl)-N-{[1,1-biphenyl]-4-yl}-N-[(thiophen-3-yl)methyl]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4860 | N-(4-tert-butylphenyl)-N-[(pyridin-3-yl)methyl]-1H-imidazole-4-carboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (49 %) | NA | 26190463 |
DrugRepV_4861 | 2-methyl-N-{4-[2-(4-phenyl-1H-1,2,3-triazol-1-yl)-N-[(thiophen-3-yl)methyl]acetamido]phenyl}propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (25 %) | NA | 26190463 |
DrugRepV_4862 | N-(4-tert-butylphenyl)-N-[(pyridin-3-yl)methyl]furan-3-carboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (24 %) | NA | 26190463 |
DrugRepV_4863 | 2-methyl-N-(4-{N-[(thiophen-3-yl)methyl]-2-[4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl]acetamido}phenyl)propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_4864 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1-methyl-1H-imidazol-4-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4865 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(benzylcarbamoyl)(3-fluorophenyl)methyl]acetamido]phenyl}-2-methylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4866 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-(4-acetamidophenyl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4867 | N-tert-butyl-2-(N-{2-cyano-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4868 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(1H-indol-3-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4869 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}cyclopropanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4870 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(benzylcarbamoyl)(3-fluorophenyl)methyl]acetamido]phenyl}cyclobutanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4871 | N-tert-butyl-2-(N-{4-[(fluoromethoxy)methyl]phenyl}-2-(1H-indol-3-yl)acetamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4872 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}benzamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4873 | N-tert-butyl-2-[2-(1H-indol-3-yl)-N-[4-(propan-2-yl)phenyl]acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4874 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(benzylcarbamoyl)(3-fluorophenyl)methyl]acetamido]phenyl}cyclopropanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4875 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1,3-oxazol-5-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4876 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-imidazol-4-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4877 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4878 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-imidazol-4-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4879 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}-1,2-oxazole-5-carboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4880 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-imidazol-4-yl)formamido]-2-(pyrimidin-5-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4881 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}-2-methylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4882 | N-{4-[2-(1H-1,3-benzodiazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4883 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-(4-acetamidophenyl)acetamido]-N-tert-butyl-2-(3-fluorophenyl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4884 | 2-[N-(4-aminophenyl)-2-(1H-1,2,3-benzotriazol-1-yl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4885 | (2S)-N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4886 | N-{4-[2-(1H-1,3-benzodiazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}-2-methylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4887 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1,3-oxazol-5-yl)formamido]-2-(pyrimidin-5-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 26190463 |
DrugRepV_4888 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}thiophene-2-carboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (26 %) | NA | 26190463 |
DrugRepV_4889 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}cyclobutanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4890 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}cyclohexanecarboxamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4891 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (34 %) | NA | 26190463 |
DrugRepV_4892 | N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}-2,2-dimethylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4893 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-(4-fluorophenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (53 %) | NA | 26190463 |
DrugRepV_4894 | N-tert-butyl-2-[N-cyclopropyl-2-(1H-indol-3-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (49 %) | NA | 26190463 |
DrugRepV_4895 | N-tert-butyl-2-[N-cyclopropyl-2-(pyridin-3-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (48 %) | NA | 26190463 |
DrugRepV_4896 | N-tert-butyl-2-[N-(4-fluorophenyl)-2-(pyridin-3-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (47 %) | NA | 26190463 |
DrugRepV_4897 | N-tert-butyl-2-[N-cyclopropyl-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (43 %) | NA | 26190463 |
DrugRepV_4898 | N-tert-butyl-2-{N-cyclopropyl-1-[5-(trifluoromethyl)pyridin-2-yl]formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (42 %) | NA | 26190463 |
DrugRepV_4899 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(pyrazin-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (41 %) | NA | 26190463 |
DrugRepV_4900 | N-tert-butyl-2-{N-[4-(propan-2-yl)phenyl]-2-(pyridin-3-yl)acetamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (41 %) | NA | 26190463 |
DrugRepV_4901 | N-tert-butyl-2-[N-(4-fluorophenyl)-2-(1H-indol-3-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (41 %) | NA | 26190463 |
DrugRepV_4902 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (41 %) | NA | 26190463 |
DrugRepV_4903 | (2S)-2-{N-[4-(butan-2-yl)phenyl]-1-(furan-2-yl)formamido}-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (39 %) | NA | 26190463 |
DrugRepV_4904 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyridazin-4-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (35 %) | NA | 26190463 |
DrugRepV_4905 | N-tert-butyl-2-[1-(3-methylfuran-2-yl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (36 %) | NA | 26190463 |
DrugRepV_4906 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (34 %) | NA | 26190463 |
DrugRepV_4907 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-(4-acetamidophenyl)acetamido]-2-(3-fluorophenyl)-N-phenylacetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (32 %) | NA | 26190463 |
DrugRepV_4908 | N-tert-butyl-2-{N-[4-(difluoromethoxy)phenyl]-1-(furan-2-yl)formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (31 %) | NA | 26190463 |
DrugRepV_4909 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(1H-indol-3-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (31 %) | NA | 26190463 |
DrugRepV_4910 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(1H-pyrrol-3-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (31 %) | NA | 26190463 |
DrugRepV_4911 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1,3-oxazol-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (30 %) | NA | 26190463 |
DrugRepV_4912 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-[5-(trifluoromethyl)pyridin-2-yl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (29 %) | NA | 26190463 |
DrugRepV_4913 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-2-(pyridin-3-yl)acetamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (29 %) | NA | 26190463 |
DrugRepV_4914 | [(tert-butylcarbamoyl)(pyridin-3-yl)methyl](4-tert-butylphenyl)carbamic acid | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (29 %) | NA | 26190463 |
DrugRepV_4915 | 2-[2-(1H-1,3-benzodiazol-1-yl)-N-(4-methanesulfonamidophenyl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (28 %) | NA | 26190463 |
DrugRepV_4916 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-pyrazol-5-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (28 %) | NA | 26190463 |
DrugRepV_4917 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (28 %) | NA | 26190463 |
DrugRepV_4918 | N-tert-butyl-2-{N-[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]-1-(furan-2-yl)formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (28 %) | NA | 26190463 |
DrugRepV_4919 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (28 %) | NA | 26190463 |
DrugRepV_4920 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-(4-methanesulfonamidophenyl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (27 %) | NA | 26190463 |
DrugRepV_4921 | N-tert-butyl-2-[N-(4-acetamidophenyl)-2-(1H-1,2,3-triazol-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (27 %) | NA | 26190463 |
DrugRepV_4922 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(4-chlorophenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (27 %) | NA | 26190463 |
DrugRepV_4923 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(5-methylfuran-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (26 %) | NA | 26190463 |
DrugRepV_4924 | N-tert-butyl-2-[2-(naphthalen-1-yl)-N-[4-(propan-2-yl)phenyl]acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (26 %) | NA | 26190463 |
DrugRepV_4925 | N-tert-butyl-2-(4-tert-butylphenyl)-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (26 %) | NA | 26190463 |
DrugRepV_4926 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(naphthalen-1-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (26 %) | NA | 26190463 |
DrugRepV_4927 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-2-(1H-indol-3-yl)acetamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (25 %) | NA | 26190463 |
DrugRepV_4928 | N-tert-butyl-2-{N-[4-(propan-2-yl)phenyl]-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (25 %) | NA | 26190463 |
DrugRepV_4929 | N-tert-butyl-2-[2-(1H-indol-3-yl)-N-[4-(propan-2-yl)phenyl]acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (25 %) | NA | 26190463 |
DrugRepV_4930 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(2-methylpropoxy)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (25 %) | NA | 26190463 |
DrugRepV_4931 | 2-{N-[4-(benzyloxy)phenyl]-1-(furan-2-yl)formamido}-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (25 %) | NA | 26190463 |
DrugRepV_4932 | N-tert-butyl-2-{N-[4-(propan-2-yl)phenyl]-2-(pyridin-3-yl)acetamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (24 %) | NA | 26190463 |
DrugRepV_4933 | N-tert-butyl-2-[N-(4-fluorophenyl)-2-(pyridin-3-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (24 %) | NA | 26190463 |
DrugRepV_4934 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(1H-imidazol-4-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (24 %) | NA | 26190463 |
DrugRepV_4935 | N-tert-butyl-2-{N-[4-(difluoromethoxy)phenyl]-1-(1H-indazol-3-yl)formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (24 %) | NA | 26190463 |
DrugRepV_4936 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(pyridin-3-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (23 %) | NA | 26190463 |
DrugRepV_4937 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-indazol-3-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (23 %) | NA | 26190463 |
DrugRepV_4938 | N-tert-butyl-2-(N-{2,6-difluoro-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (23 %) | NA | 26190463 |
DrugRepV_4939 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-methoxyacetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (23 %) | NA | 26190463 |
DrugRepV_4940 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(pyridin-3-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (23 %) | NA | 26190463 |
DrugRepV_4941 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-cyclopropylformamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (23 %) | NA | 26190463 |
DrugRepV_4942 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (22 %) | NA | 26190463 |
DrugRepV_4943 | N-tert-butyl-2-[N-cyclopropyl-2-(naphthalen-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (22 %) | NA | 26190463 |
DrugRepV_4944 | N-tert-butyl-2-[N-(4-fluorophenyl)-2-(naphthalen-1-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (22 %) | NA | 26190463 |
DrugRepV_4945 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-imidazol-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (22 %) | NA | 26190463 |
DrugRepV_4946 | 2-(N-{[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (22 %) | NA | 26190463 |
DrugRepV_4947 | N-tert-butyl-2-[N-(4-fluorophenyl)-2-(1H-indol-3-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (22 %) | NA | 26190463 |
DrugRepV_4948 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4949 | N-tert-butyl-2-[N-cyclopropyl-1-(1H-indazol-3-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4950 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-2-(naphthalen-1-yl)acetamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4951 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(4-fluorophenyl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4952 | N-tert-butyl-2-[1-(1H-indazol-3-yl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4953 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4954 | N-tert-butyl-2-[N-cyclopropyl-1-(1H-indazol-3-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4955 | N-tert-butyl-2-[1-(furan-2-yl)-N-{4-[(1E)-2-phenylethenyl]phenyl}formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4956 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (21 %) | NA | 26190463 |
DrugRepV_4957 | (2R)-2-{N-[4-(butan-2-yl)phenyl]-1-(furan-2-yl)formamido}-N-tert-butyl-2-(pyridin-4-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4958 | N-tert-butyl-2-[N-(4-acetamidophenyl)-2-[4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl]acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4959 | 2-{N-[4-(butan-2-yloxy)phenyl]-1-(furan-2-yl)formamido}-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4960 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-cyclopropylformamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4961 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-phenylacetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4962 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4963 | N-tert-butyl-2-{N-[4-(propan-2-yl)phenyl]-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (20 %) | NA | 26190463 |
DrugRepV_4964 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4965 | 2-[1-(1-benzofuran-3-yl)-N-(4-tert-butylphenyl)formamido]-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4966 | N-tert-butyl-2-[N-(4-acetamidophenyl)-2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4967 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-[5-(trifluoromethyl)pyridin-2-yl]formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4968 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(2-methyl-1H-1,3-benzodiazol-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4969 | N-tert-butyl-2-[1-(furan-2-yl)-N-(4-phenoxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4970 | 2-methylpropyl N-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]acetamido]phenyl}carbamate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4971 | N-(4-{N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]-2-(2-methyl-1H-imidazol-1-yl)acetamido}phenyl)propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (19 %) | NA | 26190463 |
DrugRepV_4972 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(oxolan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4973 | N-tert-butyl-2-[N-cyclopropyl-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4974 | 2-[N-(4-aminophenyl)-2-(1H-1,3-benzodiazol-1-yl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4975 | N-tert-butyl-2-(N-{2,3-difluoro-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4976 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-1-[5-(trifluoromethyl)pyridin-2-yl]formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4977 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4978 | N-tert-butyl-2-[N-cyclopropyl-1-(furan-2-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4979 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(3-methoxyphenoxy)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4980 | N-(4-{N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]-2-(2-methyl-1H-imidazol-1-yl)acetamido}phenyl)-2-methylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4981 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-pyrrol-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4982 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(4-cyanophenyl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4983 | N-tert-butyl-2-{N-[4-(propan-2-yl)phenyl]-1-[6-(trifluoromethyl)pyridin-3-yl]formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4984 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-2-(pyridin-3-yl)acetamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4985 | 2-[N-(adamantan-1-yl)-1-(furan-2-yl)formamido]-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (18 %) | NA | 26190463 |
DrugRepV_4986 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4987 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-pyrazol-3-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4988 | N-tert-butyl-2-[N-(4-acetamidophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4989 | tert-butyl 2-(4-{N-[(tert-butylcarbamoyl)(pyridin-3-yl)methyl]furan-2-amido}phenyl)-1H-pyrrole-1-carboxylate | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4990 | N-tert-butyl-2-{N-[4-(difluoromethoxy)phenyl]-1-(1H-indazol-3-yl)formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4991 | N-tert-butyl-2-[N-cyclopropyl-2-(1H-indol-3-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4992 | 2-[N-(4-aminophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4993 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-2-(naphthalen-1-yl)acetamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4994 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-[6-(trifluoromethyl)pyridin-3-yl]formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4995 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(3-methoxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4996 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(2-methoxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (17 %) | NA | 26190463 |
DrugRepV_4997 | N-tert-butyl-2-(N-{3-cyano-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_4998 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyrimidin-5-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_4999 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-(furan-2-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5000 | 2-[N-(adamantan-1-yl)-2-(1H-1,2,3-benzotriazol-1-yl)acetamido]-N-benzyl-2-(3-fluorophenyl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5001 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(thiophen-3-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5002 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-[5-(trifluoromethyl)furan-2-yl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5003 | N-tert-butyl-2-[N-cyclopropyl-2-(pyridin-3-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5004 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-[4-(fluoromethoxy)phenyl]formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5005 | N-tert-butyl-2-(N-{2,4-difluoro-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5006 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-indazol-3-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5007 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(1H-pyrrol-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5008 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(4-methoxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5009 | 2-[N-(4-benzenesulfonamidophenyl)-1-(furan-2-yl)formamido]-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5010 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(1H-1,2,3-triazol-4-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5011 | 2-(N-{bicyclo[2.2.1]heptan-2-yl}-1-(furan-2-yl)formamido)-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5012 | N-tert-butyl-2-{N-[4-(2-fluoropyridin-4-yl)phenyl]-1-(furan-2-yl)formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (16 %) | NA | 26190463 |
DrugRepV_5013 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-{bicyclo[2.2.1]heptan-2-yl}acetamido]-N-tert-butyl-2-(3-fluorophenyl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5014 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(pyridin-3-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5015 | 2-[2-(1H-1,3-benzodiazol-1-yl)-N-(4-tert-butylphenyl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5016 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(naphthalen-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5017 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-[6-(trifluoromethyl)pyridin-3-yl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5018 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5019 | N-tert-butyl-2-{N-[4-(propan-2-yl)phenyl]-1-[6-(trifluoromethyl)pyridin-3-yl]formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5020 | N-tert-butyl-2-{N-[4-(fluoromethoxy)phenyl]-1-[6-(trifluoromethyl)pyridin-3-yl]formamido}-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5021 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-[4-(fluoromethoxy)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5022 | N-tert-butyl-2-[N-(4-fluorophenyl)-2-(naphthalen-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (15 %) | NA | 26190463 |
DrugRepV_5023 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(5,6,7,8-tetrahydronaphthalen-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5024 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-(1H-indazol-3-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5025 | N-tert-butyl-2-(N-{4-cyano-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5026 | N-(4-{N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]-2-(2-methyl-1H-1,3-benzodiazol-1-yl)acetamido}phenyl)-2-methylpropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5027 | 2-[N-(adamantan-1-yl)-2-(1H-1,2,3-benzotriazol-1-yl)acetamido]-N-tert-butyl-2-(3-fluorophenyl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5028 | 2-[2-(1H-1,3-benzodiazol-1-yl)-N-(4-acetamidophenyl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5029 | 2-{N-[4-(benzyloxy)phenyl]-1-(furan-2-yl)formamido}-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5030 | N-tert-butyl-2-[N-cyclopropyl-1-(5,6,7,8-tetrahydronaphthalen-1-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5031 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(pyrimidin-5-yl)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5032 | 2-[N-(4-aminophenyl)-2-(2-methyl-1H-1,3-benzodiazol-1-yl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (14 %) | NA | 26190463 |
DrugRepV_5033 | N-tert-butyl-2-{N-[4-(difluoromethoxy)phenyl]-1-(furan-2-yl)formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5034 | N-tert-butyl-2-[N-(4-methanesulfonamidophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5035 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(pyrimidin-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5036 | N-tert-butyl-2-[2-(naphthalen-1-yl)-N-[4-(propan-2-yl)phenyl]acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5037 | N-tert-butyl-2-[1-(furan-2-yl)-N-[4-(propan-2-yloxy)phenyl]formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5038 | N-tert-butyl-2-[1-(4-cyanophenyl)-N-(4-fluorophenyl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5039 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(pyridin-3-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5040 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(pyridin-4-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5041 | N-[(tert-butylcarbamoyl)(pyridin-3-yl)methyl]-N-(4-tert-butylphenyl)-3,3,3-trifluoropropanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (13 %) | NA | 26190463 |
DrugRepV_5042 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(5-chlorofuran-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5043 | N-tert-butyl-2-{N-cyclopropyl-1-[6-(trifluoromethyl)pyridin-3-yl]formamido}-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5044 | N-tert-butyl-2-[N-(4-ethoxyphenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5045 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(1H-pyrazol-4-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5046 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-{bicyclo[2.2.1]heptan-2-yl}acetamido]-N-benzyl-2-(3-fluorophenyl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5047 | N-tert-butyl-2-(N-{3,4-difluoro-[1,1-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5048 | N-tert-butyl-2-[1-(furan-2-yl)-N-(4-methanesulfonamidophenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5049 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(pyridin-3-yl)formamido]-2-(pyridin-2-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (12 %) | NA | 26190463 |
DrugRepV_5050 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(4-hydroxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5051 | N-tert-butyl-2-[N-(4-fluorophenyl)-1-(1H-indazol-3-yl)formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5052 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5053 | N-tert-butyl-2-[N-cyclopropyl-2-(naphthalen-1-yl)acetamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5054 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5055 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(4-cyanophenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5056 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(2-hydroxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5057 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(1H-pyrazol-5-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5058 | N-tert-butyl-2-[1-(1H-indazol-3-yl)-N-[4-(propan-2-yl)phenyl]formamido]-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (11 %) | NA | 26190463 |
DrugRepV_5059 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(3-hydroxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (10 %) | NA | 26190463 |
DrugRepV_5060 | N-tert-butyl-2-[1-(furan-2-yl)-N-(4-propoxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (10 %) | NA | 26190463 |
DrugRepV_5061 | N-tert-butyl-2-[1-(furan-2-yl)-N-(4-methoxyphenyl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (10 %) | NA | 26190463 |
DrugRepV_5062 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(1H-imidazol-4-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (9 %) | NA | 26190463 |
DrugRepV_5063 | 2-[2-(1H-1,2,3-benzotriazol-1-yl)-N-(4-tert-butylphenyl)acetamido]-N-tert-butyl-2-(thiophen-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (9 %) | NA | 26190463 |
DrugRepV_5064 | 2-[N-(4-benzylphenyl)-1-(furan-2-yl)formamido]-N-tert-butyl-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (8 %) | NA | 26190463 |
DrugRepV_5065 | N-(4-{N-[(tert-butylcarbamoyl)(thiophen-3-yl)methyl]-2-(2-methyl-1H-1,3-benzodiazol-1-yl)acetamido}phenyl)propanamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (8 %) | NA | 26190463 |
DrugRepV_5066 | N-tert-butyl-2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-2-(6-methylpyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (8 %) | NA | 26190463 |
DrugRepV_5067 | N-tert-butyl-2-[N-cyclohexyl-1-(furan-2-yl)formamido]-2-(pyridin-3-yl)acetamide | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (6 %) | NA | 26190463 |
DrugRepV_5068 | Alisporivir | NA | Hepatitis C virus | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Virus yield reduction assay | Decrease (50 %) | Investigational | 27840112 |
DrugRepV_5069 | Alisporivir | NA | Hepatitis C virus | Middle East respiratory syndrome coronavirus | N3/Jordan | NA | CPE inhibition assay | Decrease (50 %) | Investigational | 27840112 |
DrugRepV_5070 | Alisporivir | NA | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | MA-15 | NA | CPE inhibition assay | Decrease (50 %) | Investigational | 27840112 |
DrugRepV_5089 | S-Nitroso-N-acetylpenicillamine | NA | NA | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Immunoflourescence assay | Decrease (>90 %) | NA | 16632039 |
DrugRepV_5090 | S-Nitroso-N-acetylpenicillamine | NA | NA | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Western blot | Decrease | NA | 16632039 |
DrugRepV_5091 | S-Nitroso-N-acetylpenicillamine | NA | NA | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Real-time PCR | Decrease | NA | 16632039 |
DrugRepV_5100 | 2-Deoxy-2-fluorocytidine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Decrease (50 %) | NA | 29024765 |
DrugRepV_5102 | 2-Chloroadenosine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Increase (-26 %) | NA | 29024765 |
DrugRepV_5103 | 2-Deoxy-2-fluorocytidine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Decrease (98 %) | NA | 29024765 |
DrugRepV_5104 | 2-C-Methylcytidine | NA | HCV | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (4 %) | Experimental | 29024765 |
DrugRepV_5105 | 2-C-Methyluridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Increase (-9 %) | NA | 29024765 |
DrugRepV_5106 | 2-O-Methylcytidine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (7 %) | NA | 29024765 |
DrugRepV_5107 | 2-O-Methyluridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (7 %) | NA | 29024765 |
DrugRepV_5108 | 3-Deazauridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (19 %) | NA | 29024765 |
DrugRepV_5110 | 5-Azidouridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (28 %) | NA | 29024765 |
DrugRepV_5111 | 5-Bromouridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (1 %) | NA | 29024765 |
DrugRepV_5112 | 5-Chlorouridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (0 %) | NA | 29024765 |
DrugRepV_5113 | 5-Fluorouridine | NA | Cancer | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (7 %) | Experimental | 29024765 |
DrugRepV_5114 | 5-Methylcytidine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (6 %) | NA | 29024765 |
DrugRepV_5115 | 6-Aza-2-thiouridine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (17 %) | NA | 29024765 |
DrugRepV_5116 | 6-Azauridine | NA | Cancer | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (36 %) | NA | 29024765 |
DrugRepV_5117 | 7-DMA | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (26 %) | NA | 29024765 |
DrugRepV_5118 | 8-Azaadenosine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Decrease (92 %) | NA | 29024765 |
DrugRepV_5119 | 8-Azidoadenosine | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Decrease (87 %) | NA | 29024765 |
DrugRepV_5122 | BCX4430 | NA | Ebola virus | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (18 %) | Investigational | 29024765 |
DrugRepV_5129 | PSI-6130 | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Increase (-6 %) | NA | 29024765 |
DrugRepV_5130 | PSI-6206 | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Increase (-1 %) | NA | 29024765 |
DrugRepV_5131 | PSI-7976 | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (9 %) | NA | 29024765 |
DrugRepV_5133 | R-1479 | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (15 %) | NA | 29024765 |
DrugRepV_5135 | RO-9187 | NA | NA | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (12 %) | NA | 29024765 |
DrugRepV_5141 | PF-4708671 | NA | NA | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Decrease (50 %) | NA | 29652799 |
DrugRepV_5142 | Pteridinone | NA | NA | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Increase (50 %) | NA | 29652799 |
DrugRepV_5143 | PF-4708671-BI-D1870 | NA | NA | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Decrease (50 %) | NA | 29652799 |
DrugRepV_5144 | SB203580 | NA | NA | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Decrease (50 %) | NA | 29652799 |
DrugRepV_5145 | PD0325901 | NA | Melanoma | Solid Tumour | Solid Tumors | Advanced Cancer | Breast Neoplasms | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Decrease (50 %) | Investigational | 29652799 |
DrugRepV_5147 | Rapamycin-SB203580 | NA | NA | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Decrease (50 %) | NA | 29652799 |
DrugRepV_5148 | Rapamycin-PD0325901 | NA | NA | Rift Valley fever virus | MP12ΔNSs-Luc | NA | Luciferase assay | Decrease (50 %) | NA | 29652799 |
DrugRepV_5149 | PF-4708671 | NA | NA | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | NA | 29652799 |
DrugRepV_5150 | PF-4708671 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | No significant effect (0.5 log pfu/ml) | NA | 29652799 |
DrugRepV_5151 | PF-4708671-BI-D1870 | NA | NA | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | NA | 29652799 |
DrugRepV_5152 | PF-4708671-BI-D1870 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (2 log pfu/ml) | NA | 29652799 |
DrugRepV_5153 | SB203580 | NA | NA | Rift Valley fever virus | MP12 | NA | Western blot | No significant effect | NA | 29652799 |
DrugRepV_5154 | SB203580 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | No significant effect (<0.5log pfu/ml) | NA | 29652799 |
DrugRepV_5155 | PD0325901 | NA | Melanoma | Solid Tumour | Solid Tumors | Advanced Cancer | Breast Neoplasms | Rift Valley fever virus | MP12 | NA | Western blot | Decrease | Investigational | 29652799 |
DrugRepV_5156 | PD0325901 | NA | Melanoma | Solid Tumour | Solid Tumors | Advanced Cancer | Breast Neoplasms | Rift Valley fever virus | MP12 | NA | Plaque assay | No significant effect (0.5log pfu/ml) | Investigational | 29652799 |
DrugRepV_5158 | Rapamycin-SB203580 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (>3log pfu/ml) | NA | 29652799 |
DrugRepV_5159 | Rapamycin-PD0325901 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (3log pfu/ml) | NA | 29652799 |
DrugRepV_5160 | Benzavir-2 | NA | NA | Rift Valley fever virus | rRVFV?NSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 29386590 |
DrugRepV_5161 | Benzavir-1 | NA | NA | Rift Valley fever virus | rRVFV?NSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 29386590 |
DrugRepV_5162 | 2-[[4-chloro-2-[(2-fluorobenzoyl)amino]benzoyl]amino]benzoic acid | NA | NA | Rift Valley fever virus | rRVFV?NSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 29386590 |
DrugRepV_5163 | 2-[[2-(2,2-dimethylpropanoylamino)benzoyl]amino]benzoic acid | NA | NA | Rift Valley fever virus | rRVFV?NSs::Katushka | NA | Fluorescence-based assay | No significant effect (50 %) | NA | 29386590 |
DrugRepV_5164 | 2-[[2-(cyclohexanecarbonylamino)benzoyl]amino]benzoic acid | NA | NA | Rift Valley fever virus | rRVFV?NSs::Katushka | NA | Fluorescence-based assay | No significant effect (50 %) | NA | 29386590 |
DrugRepV_5171 | 3-(2,3-Diphenyl-1H-indol-1-yl)-N-(3-hydroxybenzylidene) propanohydrazide | NA | NA | Rift Valley fever virus | rRVFVΔNSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26762502 |
DrugRepV_5172 | 1-(3,5-Di-tert-butyl-4-hydroxyphenyl)-2-(2-imino-3-(4-methylbenzyl)-2,3- dihydro-1H-benzimidazol-1-yl)ethanone hydrobromide | NA | NA | Rift Valley fever virus | rRVFVΔNSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26762502 |
DrugRepV_5173 | 4-Hydroxy-3-methoxybenzaldehyde (4-(3,4-dimethoxyphenyl)-6-phenyl-2- pyrimidinyl)hydrazone | NA | NA | Rift Valley fever virus | rRVFVΔNSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26762502 |
DrugRepV_5174 | 1-(3,4-Dichlorophenyl)-3-(4-(3,4-dimethoxyphenyl)-1-methylpyrrolidin-3- yl)urea | NA | NA | Rift Valley fever virus | rRVFVΔNSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26762502 |
DrugRepV_5175 | 2-Chloro-N-(2-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-ylcarbamoyl)phenyl) benzamide | NA | NA | Rift Valley fever virus | rRVFVΔNSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26762502 |
DrugRepV_5176 | 2-(4-Bromo-5-chlorothiophene-2-sulfonamido)-N-(4-fluorophenyl) benzamide | NA | NA | Rift Valley fever virus | rRVFVΔNSs::Katushka | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26762502 |
DrugRepV_5180 | C795-0925 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5181 | D011-2120 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5182 | F694-1532 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5183 | G202-0362 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5186 | C795-0925 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5187 | D011-2120 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5188 | F694-1532 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5189 | G202-0362 | NA | NA | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5192 | C795-0925 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5193 | D011-2120 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5194 | F694-1532 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5195 | G202-0362 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5197 | C795-0925 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5198 | D011-2120 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5199 | F694-1532 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5200 | G202-0362 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5202 | C795-0925 | NA | NA | Lassa virus | Josiah | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5203 | D011-2120 | NA | NA | Lassa virus | Josiah | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5204 | F694-1532 | NA | NA | Lassa virus | Josiah | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5208 | Curcumin | NA | Depressive disorder | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (3 log pfu/ml) | Approved | 22847000 |
DrugRepV_5209 | SC-514 | NA | NA | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (<1 log pfu/ml) | NA | 22847000 |
DrugRepV_5210 | Curcumin | NA | Depressive disorder | Rift Valley fever virus | ZH501 | NA | Plaque assay | Decrease (4 log pfu/ml) | Approved | 22847000 |
DrugRepV_5211 | Curcumin | NA | Depressive disorder | Rift Valley fever virus | MP12 | NA | Plaque assay | Decrease (5 log pfu/ml) | Approved | 22847000 |
DrugRepV_5213 | Quinacrine Dihydrochloride | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Rift Valley fever virus | NA | NA | RVFV nucleocapsid (N) protein RNA-binding activity | Decrease (50 %) | Investigational | 22644268 |
DrugRepV_5214 | N-methyl-2,3-diphenyl-1,2,4-thiadiazol-5-imine;hydrobromide | NA | NA | Rift Valley fever virus | NA | NA | RVFV nucleocapsid (N) protein RNA-binding activity | Decrease (50 %) | NA | 22644268 |
DrugRepV_5215 | 4-(3,6-dioxocyclohexa-1,4-dien-1-yl)benzoic acid | NA | NA | Rift Valley fever virus | NA | NA | RVFV nucleocapsid (N) protein RNA-binding activity | Decrease (50 %) | NA | 22644268 |
DrugRepV_5216 | BTB 11461 | NA | NA | Rift Valley fever virus | NA | NA | RVFV nucleocapsid (N) protein RNA-binding activity | Decrease (50 %) | NA | 22644268 |
DrugRepV_5226 | Ribamidine | NA | NA | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Neutral red uptake assay | Decrease (50 %) | Investigational | 15026198 |
DrugRepV_5227 | 6-Azauridine | NA | Cancer | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5228 | Selenazofurin | NA | NA | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5231 | Ribamidine | NA | NA | Crimean-Congo hemorrhagic fever virus | Spu 128/81 | NA | Neutral red uptake assay | Decrease (50 %) | Investigational | 15026198 |
DrugRepV_5232 | 6-Azauridine | NA | Cancer | Crimean-Congo hemorrhagic fever virus | Spu 128/81 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5233 | Selenazofurin | NA | NA | Crimean-Congo hemorrhagic fever virus | Spu 128/81 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5236 | Ribamidine | NA | NA | Crimean-Congo hemorrhagic fever virus | Hy-13 | NA | Neutral red uptake assay | Decrease (50 %) | Investigational | 15026198 |
DrugRepV_5237 | 6-Azauridine | NA | Cancer | Crimean-Congo hemorrhagic fever virus | Hy-13 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5238 | Selenazofurin | NA | NA | Crimean-Congo hemorrhagic fever virus | Hy-13 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5241 | Ribamidine | NA | NA | Crimean-Congo hemorrhagic fever virus | UG3010 | NA | Neutral red uptake assay | Decrease (50 %) | Investigational | 15026198 |
DrugRepV_5242 | 6-Azauridine | NA | Cancer | Crimean-Congo hemorrhagic fever virus | UG3010 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5243 | Selenazofurin | NA | NA | Crimean-Congo hemorrhagic fever virus | UG3010 | NA | Neutral red uptake assay | Decrease (50 %) | NA | 15026198 |
DrugRepV_5245 | Cytarabine | NA | Leukemia | Variola virus | Harvey | NA | Focus forming assay | Decrease (82.3 %) | Approved | 198636 |
DrugRepV_5246 | Cytarabine | NA | Leukemia | Variola virus | Harvey | NA | Focus forming assay | Decrease (30.2 %) | Approved | 198636 |
DrugRepV_5247 | 6-Azauridine | NA | Cancer | Variola virus | Harvey | NA | Focus forming assay | Decrease (1.2 %) | NA | 198636 |
DrugRepV_5248 | Cytarabine | NA | Leukemia | Variola virus | Yamamoto P | NA | Focus forming assay | Decrease (66.1 %) | Approved | 198636 |
DrugRepV_5249 | 6-Azauridine | NA | Cancer | Variola virus | Yamamoto P | NA | Focus forming assay | Decrease (2.9 %) | NA | 198636 |
DrugRepV_5250 | Cytarabine | NA | Leukemia | Variola virus | Butler | NA | Focus forming assay | Decrease (44.4 %) | Approved | 198636 |
DrugRepV_5251 | 6-Azauridine | NA | Cancer | Variola virus | Butler | NA | Focus forming assay | No significant effect (No inhibition %) | NA | 198636 |
DrugRepV_5253 | beta-D-cyclopentenyl cytosine | NA | NA | Variola virus | Bangladesh 1975 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5254 | beta-D-cyclopentenyl cytosine | NA | NA | Variola virus | 7124 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5255 | beta-D-cyclopentenyl-5-iodocytidine | NA | NA | Variola virus | Bangladesh 1975 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5256 | beta-D-cyclopentenyl-5-iodocytidine | NA | NA | Variola virus | 7124 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5257 | beta-D-Cyclopentenyl-5-chlorocytidine | NA | NA | Variola virus | Bangladesh 1975 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5258 | beta-D-Cyclopentenyl-5-chlorocytidine | NA | NA | Variola virus | 7124 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5259 | beta-D-cyclopentenyl-5-bromocytidine | NA | NA | Variola virus | Bangladesh 1975 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5260 | beta-D-cyclopentenyl-5-bromocytidine | NA | NA | Variola virus | 7124 | NA | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_5261 | Delphinidin Chloride | NA | NA | Zika virus | MR766 | NA | Plaque assay | Decrease (102 Log) | NA | 28744282 |
DrugRepV_5263 | Delphinidin Chloride | NA | NA | Zika virus | PA259459 | NA | Plaque assay | Decrease | NA | 28744282 |
DrugRepV_5265 | Tetra-O-methyl nordihydroguaiaretic acid (M4N) | NA | Brain and Central Nervous System Tumors | Zika virus | PA259459 | NA | Plaque assay | Decrease (50 %) | Investigational | 28507114 |
DrugRepV_5266 | Tetra-O-methyl nordihydroguaiaretic acid (M4N) | NA | Brain and Central Nervous System Tumors | Zika virus | PA259459 | NA | Plaque assay | Decrease (50 %) | Investigational | 28507114 |
DrugRepV_5267 | 25-Hydroxycholesterol | NA | NA | Lassa virus | Josiah | NA | TCID50 assay | Decrease (>1.1 Log) | Experimental | 27999160 |
DrugRepV_5268 | 25-Hydroxycholesterol | NA | NA | Lassa virus | Josiah | NA | TCID50 assay | Decrease (1.4 Log) | Experimental | 27999160 |
DrugRepV_5273 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5274 | diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5275 | diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5276 | 1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5277 | 2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5278 | 1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5279 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5280 | {2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5281 | 4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5282 | 4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5283 | 4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5284 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5285 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5286 | 4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5287 | 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5288 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5289 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5290 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5291 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5292 | diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5293 | diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5294 | 1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5295 | 2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5296 | 1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5297 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5298 | {2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5299 | 4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5300 | 4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5301 | 4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5302 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5303 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5304 | 4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5305 | 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5306 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5307 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5308 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide | NA | NA | Lassa virus | AV | NA | Real-time PCR | Decrease (90 %) | NA | 15451189 |
DrugRepV_5309 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5310 | diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5311 | diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5312 | 1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5313 | 2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5314 | 1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5315 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5316 | {2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5317 | 4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5318 | 4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5319 | 4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5320 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5321 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5322 | 4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5323 | 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5324 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5325 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5326 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5327 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5328 | diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5329 | diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5330 | 1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5331 | 2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5332 | 1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5333 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5334 | {2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5335 | 4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5336 | 4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5337 | 4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5338 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5339 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5340 | 4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5341 | 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5342 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5343 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5344 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5345 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5346 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5347 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5348 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5349 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5350 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5351 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5352 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5353 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5354 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5355 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5356 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Lassa virus | AV | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5357 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5358 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5359 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5360 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5377 | 2-deoxy-2-fluorocytidine | NA | NA | Lassa virus | Josiah | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5378 | 5-fluorouridine | NA | Cancer | Lassa virus | Josiah | NA | Minigenome assays | Decrease (50 %) | Experimental | 27771389 |
DrugRepV_5379 | 8-Azaadenosine | NA | NA | Lassa virus | Josiah | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5380 | 8-Azidoadenosine | NA | NA | Lassa virus | Josiah | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5381 | Toyocamycin | NA | NA | Lassa virus | Josiah | NA | Minigenome assays | Decrease (50 %) | Experimental | 27771389 |
DrugRepV_5382 | 6-Azauridine | NA | Cancer | Lassa virus | Josiah | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5383 | 8-Azaadenosine | NA | NA | Ebola virus | Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2014 | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5384 | Toyocamycin | NA | NA | Ebola virus | Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2015 | NA | Minigenome assays | Decrease (50 %) | Experimental | 27771389 |
DrugRepV_5385 | 6-Azauridine | NA | Cancer | Ebola virus | Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2016 | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5386 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | NA | NA | qRT-PCR | Decrease | Investigational | 31307979 |
DrugRepV_5387 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Chikungunya virus | NA | NA | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5388 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | NA | NA | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5389 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Influenza virus | NA | | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5390 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Middle East respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5391 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Rift Valley fever virus | NA | NA | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5392 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Zika virus | NA | NA | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5393 | Zoniporide | NA | NA | Lassa virus | Josiah | NA | Luciferase assay | Decrease (50 %) | NA | 30700611 |
DrugRepV_5394 | Zoniporide | NA | NA | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | NA | 30700611 |
DrugRepV_5399 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | Lassa virus | Josiah | NA | Luciferase assay | Decrease (50 %) | Investigational | 30700611 |
DrugRepV_5400 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Investigational | 30700611 |
DrugRepV_5401 | Arbidol | NA | Viral infection | Lassa virus | Josiah | NA | Luciferase assay | Decrease (50 %) | Investigational | 30700611 |
DrugRepV_5402 | Arbidol | NA | Viral infection | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Investigational | 30700611 |
DrugRepV_5410 | Desethylamodiaquine | NA | NA | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (50 %) | NA | 30801742 |
DrugRepV_5411 | Desethylchloroquine | NA | NA | Zika virus | PLCal_ZV | NA | MTT assay | Decrease (50 %) | NA | 30801742 |
DrugRepV_5413 | Desethylamodiaquine | NA | NA | Zika virus | MR 766 | NA | MTT assay | Decrease (50 %) | NA | 30801742 |
DrugRepV_5414 | Desethylchloroquine | NA | NA | Zika virus | MR 766 | NA | MTT assay | Decrease (50 %) | NA | 30801742 |
DrugRepV_5416 | Desethylamodiaquine | NA | NA | Zika virus | PRVABC59 | NA | MTT assay | Decrease (50 %) | NA | 30801742 |
DrugRepV_5417 | Desethylchloroquine | NA | NA | Zika virus | PRVABC59 | NA | MTT assay | Decrease (50 %) | NA | 30801742 |
DrugRepV_5420 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | Josiah | NA | TCID50 assay | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5421 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | Josiah | NA | RT-qPCR | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5422 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | LP | NA | NA | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5423 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | 803213 | NA | NA | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5424 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | GA391 | NA | NA | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5425 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | Josiah | NA | NA | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5426 | ST-193 | NA | NA | Lassa virus | LP | NA | NA | Decrease (50 %) | NA | 30953674 |
DrugRepV_5427 | ST-193 | NA | NA | Lassa virus | 803213 | NA | NA | Decrease (50 %) | NA | 30953674 |
DrugRepV_5428 | ST-193 | NA | NA | Lassa virus | GA391 | NA | NA | Decrease (50 %) | NA | 30953674 |
DrugRepV_5429 | ST-193 | NA | NA | Lassa virus | Josiah | NA | NA | Decrease (50 %) | NA | 30953674 |
DrugRepV_5431 | Gallium nitrate | NA | NA | Influenza virus | A/Puerto Rico/8/34 (PR8) | | Plaque reduction assay | Decrease (50 %) | Approved, Investigational | 31244822 |
DrugRepV_5435 | Gallium nitrate | NA | NA | Influenza virus | pdm09A/Mexico/InDRE4487/2009 | | Plaque reduction assay | Decrease (50 %) | Approved, Investigational | 31244822 |
DrugRepV_5439 | Gallium nitrate | NA | NA | Influenza virus | A/Victoria/36/2011 | | Plaque reduction assay | Decrease (50 %) | Approved, Investigational | 31244822 |
DrugRepV_5443 | Gallium nitrate | NA | NA | Influenza virus | A/Puerto Rico/8/34 (PR8) | | Virus inhibition assay | Decrease (5.3 log) | Approved, Investigational | 31244822 |
DrugRepV_5447 | Gallium nitrate | NA | NA | Influenza virus | pdm09A/Mexico/InDRE4487/2009 | | Virus inhibition assay | Decrease (5.2 log) | Approved, Investigational | 31244822 |
DrugRepV_5451 | Gallium nitrate | NA | NA | Influenza virus | A/Victoria/36/2011 | | Virus inhibition assay | Decrease (5.5 log) | Approved, Investigational | 31244822 |
DrugRepV_5477 | Nafamostat | NA | Blood vessel coagulation | Hemorrhagic lesions | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Investigational | 32020029 |
DrugRepV_5479 | Beta-D-N4-hydroxycytidine | NA | NA | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (50 %) | NA | 31578288 |
DrugRepV_5482 | RK-33 | NA | NA | Zika virus | Asian/Cook Islands/2014 | NA | Plaque assay | Decrease (50 %) | NA | 31936642 |
DrugRepV_5483 | RK-33 | NA | NA | Zika virus | Asian/Cook Islands/2014 | NA | qRT-PCR | Decrease (50 %) | NA | 31936642 |
DrugRepV_5487 | Novobiocin | NA | Staphylococci infections | Zika virus | NA | NA | Flow cytometry | Decrease (50 %) | Approved, Investigational, Vet approved | 31786251 |
DrugRepV_5495 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5496 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5497 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5498 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5499 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5500 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5501 | Dihydroartimesinin | NA | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Experimental, Investigational | 31882748 |
DrugRepV_5502 | Dihydroartimesinin | NA | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Experimental, Investigational | 31882748 |
DrugRepV_5506 | Anthralin | NA | Psoriasis | Influenza virus | H1N1 | | TCID50 assay | Decrease (99 %) | Approved | 32132985 |
DrugRepV_5507 | Anthralin | NA | Psoriasis | Influenza virus | H1N1 | | TCID50 assay | Decrease (99 %) | Approved | 32132985 |
DrugRepV_5508 | Amuvatinib | NA | Cancer | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Investigational | 31786250 |
DrugRepV_5510 | Azoxystrobin | NA | Fungal infections | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Experimental | 31786250 |
DrugRepV_5511 | Buparvaquone | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | NA | 31786250 |
DrugRepV_5512 | Dequalinium chloride hydrate | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | NA | 31786250 |
DrugRepV_5513 | Manassantin A | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | NA | 31786250 |
DrugRepV_5514 | Monensin sodium salt | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Experimental, Vet approved | 31786250 |
DrugRepV_5515 | Mubritinib | NA | Lung Neoplasm, Renal Neoplasm, Breast Neoplasm, Ovarian Neoplasm, and Pancreatic Neoplasm | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Investigational | 31786250 |
DrugRepV_5519 | Rotenone | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Vet approved | 31786250 |
DrugRepV_5520 | Spautin-1 | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | NA | 31786250 |
DrugRepV_5521 | Valinomycin | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Experimental | 31786250 |
DrugRepV_5523 | Tryptanthrin | NA | NA | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | NA | 31786250 |
DrugRepV_5531 | JQ1 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5532 | RVX-208 | NA | Diabetes, Atherosclerosis, and Coronary Artery Disease | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5533 | Silmitasertib | NA | Medulloblastoma | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5534 | TMCB | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5535 | Apicidin | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5538 | E-52862 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5539 | PD-144418 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5540 | RS-PPCC | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5541 | PB28 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5547 | H-89 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5548 | Merimepodib | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5552 | XL413 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5553 | CCT 365623 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5556 | ZINC1775962367 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5557 | ZINC4326719 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5558 | ZINC4511851 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5559 | ZINC95559591 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5560 | AC-55541 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5561 | AZ8838 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5563 | GB110 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5564 | S-verapamil | NA | Hypertension (high blood pressure) | Angina (chest pain) | Arrhythmia (heart rhythm disorders). | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Approved | 32353859 |
DrugRepV_5565 | AZ3451 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5566 | ABBV-744 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5567 | dBET6 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5568 | MZ1 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5569 | CPI-0610 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5570 | Sapanisertib | NA | Tumor | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5572 | Zotatifin | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5573 | Verdinexor | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5576 | WDB002 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5577 | Sanglifehrin A | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Experimental | 32353859 |
DrugRepV_5579 | Pevonedistat | NA | Lymphoma | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5580 | Ternatin 4 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5581 | 4E2RCat | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5582 | Tomivosertib | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5583 | (2R,5S,11S,14S,17R,18R,21E)-2-(2-aminoethyl)-18-methoxy-11,17-dimethyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1?,?]octacosa-1(26),21,23(27),24-tetraene-4,10,13,16-tetrone | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5584 | N-(5-{3-[(4-Hydroxyphenyl)sulfamoyl]-4-methoxyphenyl}-4-methyl-1,3-thiazol-2-yl)-2,2-dimethylpropanamide | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5585 | PS3061 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5586 | IHVR-19029 | NA | NA | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | NA | 32353859 |
DrugRepV_5590 | Nafamostat | NA | Blood vessel coagulation | Hemorrhagic lesions | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Investigational | 32353859 |
DrugRepV_5604 | Sunitinib-Erlotinib | NA | NA | Dengue virus | N124D/K128E | | NA | Increase | NA | 28240606 |
DrugRepV_5605 | Sunitinib-Erlotinib | NA | NA | Dengue virus | N124D/K128E | | Real-time PCR | Decrease (11 Fold) | NA | 28240606 |
DrugRepV_5615 | AMG-458 | NA | Cancer | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (60 %) | NA | 28099856 |
DrugRepV_5616 | AMG-458 | NA | Cancer | Dengue virus | New Guinea C | | Immunoflourescence assay | No significant effect (40 %) | NA | 28099856 |
DrugRepV_5617 | AMG-458 | NA | Cancer | Dengue virus | New Guinea C | | Immunoflourescence assay | No significant effect (5 %) | NA | 28099856 |
DrugRepV_5708 | R1479 | NA | NA | Dengue virus | MY-10340 | | Plaque assay | Decrease (50 %) | NA | 24257621 |
DrugRepV_5709 | Sunitinib-Erlotinib | NA | NA | Dengue virus | NA | | Survival assay | Increase | NA | 29753658 |
DrugRepV_5710 | Sunitinib-Erlotinib | NA | NA | Dengue virus | NA | | Plaque assay | Decrease (>5 Log (pfu/g)) | NA | 29753658 |
DrugRepV_5714 | Carrageenan | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5715 | Tannic Acid | NA | Cold sores | Diaper rash | Fever blisters | Poison ivy | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Approved | 20973722 |
DrugRepV_5716 | Tannic Acid | NA | Cold sores | Diaper rash | Fever blisters | Poison ivy | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Approved | 20973722 |
DrugRepV_5717 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Investigational | 20973722 |
DrugRepV_5718 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Investigational | 20973722 |
DrugRepV_5721 | BIBU 1361 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5722 | BIBU 1361 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5724 | 3-[(4-chloro-phenyl)-phenyl-methoxy]-tropane | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5725 | 3-[(4-chloro-phenyl)-phenyl-methoxy]-tropane | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5727 | H-89 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5728 | H-89 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5729 | MPP | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5730 | MPP | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5734 | W-9 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5735 | W-9 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5736 | AZ 10417808 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5737 | AZ 10417808 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5738 | Niguldipine | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Experimental | 20973722 |
DrugRepV_5739 | Niguldipine | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Experimental | 20973722 |
DrugRepV_5740 | 3a-bis-(4-fluorophenyl) Methoxytropane | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5741 | LE 135 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5742 | LE 135 | NA | NA | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5761 | Myriocin | NA | Bacterial infections | Dengue virus | NGC | | Plaque assay | No significant effect | NA | 25313218 |
DrugRepV_5762 | Fenretinide-Myriocin | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (4 Logs) | NA | 25313218 |
DrugRepV_5763 | Butylated Hydroxyanisole | NA | Antioxidant | Dengue virus | NGC | | Plaque assay | No significant effect | NA | 25313218 |
DrugRepV_5764 | Fenretinide-Butylated Hydroxyanisole | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (1.5 Logs) | NA | 25313218 |
DrugRepV_5766 | Fenretinide-Vitamin C | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (3 Logs) | NA | 25313218 |
DrugRepV_5775 | Allantoin | NA | NA | Dengue virus | Singapore isolates | | Plaque assay | Decrease (78 %) | Approved | 25251726 |
DrugRepV_5777 | Brucine | NA | NA | Dengue virus | Singapore isolates | | Plaque assay | Decrease (75 %) | NA | 25251726 |
DrugRepV_5778 | Dicloxacillium Sodium | NA | Bacterial infections | Dengue virus | Singapore isolates | | Plaque assay | Decrease (72 %) | Approved | 25251726 |
DrugRepV_5780 | Acrisorcin | NA | NA | Dengue virus | Singapore isolates | | Plaque assay | Decrease (72 %) | NA | 25251726 |
DrugRepV_5782 | Oxantel Pamoate | NA | NA | Dengue virus | Singapore isolates | | Plaque assay | Decrease (68 %) | NA | 25251726 |
DrugRepV_5787 | Lasalocid Sodium | NA | NA | Dengue virus | Singapore isolates | | Plaque assay | Decrease (62 %) | NA | 25251726 |
DrugRepV_5803 | Lapachaone Alpha | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (98.84 %) | NA | 22155902 |
DrugRepV_5809 | Shikonin | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (78.94 %) | NA | 22155902 |
DrugRepV_5811 | Chelerythrine Chloride | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (73.36 %) | NA | 22155902 |
DrugRepV_5812 | Skimmianine | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (61.96 %) | NA | 22155902 |
DrugRepV_5816 | Tunicamycin B | NA | Bacterial infections | Dengue virus | NA | | Immunoflourescence assay | Decrease (55.01 %) | Experimental | 22155902 |
DrugRepV_5817 | Acivicin | NA | Cancer | Dengue virus | NA | | Immunoflourescence assay | Decrease (54.32 %) | Phase I | 22155902 |
DrugRepV_5821 | Gitoxigenin | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (49.01 %) | NA | 22155902 |
DrugRepV_5822 | Kainic Acid | NA | Neuroexcitatory | Dengue virus | NA | | Immunoflourescence assay | Decrease (48.87 %) | NA | 22155902 |
DrugRepV_5825 | Diacetoxyscirpenol | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (45.55 %) | NA | 22155902 |
DrugRepV_5826 | Austricin | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (45.01 %) | NA | 22155902 |
DrugRepV_5827 | Valinomycin | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (43.34 %) | Experimental | 22155902 |
DrugRepV_5828 | Thapsigargin | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (42.9 %) | NA | 22155902 |
DrugRepV_5829 | Strophanthidin Acetate | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (41.96 %) | NA | 22155902 |
DrugRepV_5831 | Echinomycin | NA | Bacterial infections | Dengue virus | NA | | Immunoflourescence assay | Decrease (41.52 %) | NA | 22155902 |
DrugRepV_5832 | Chromomycin A3 | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (40.87 %) | NA | 22155902 |
DrugRepV_5835 | Strophanthidin Acetate | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (50 %) | NA | 22155902 |
DrugRepV_5839 | Strophanthidin Acetate | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease (98 %) | NA | 22155902 |
DrugRepV_5843 | Strophanthidin Acetate | NA | NA | Dengue virus | NA | | Plaque assay | Decrease (5 Logs reduction) | NA | 22155902 |
DrugRepV_5890 | Quinacrine Mustard | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Dengue virus | NA | | Plaque assay | Decrease (> 99 %) | Experimental | 24680954 |
DrugRepV_5908 | Quinacrine Mustard | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Experimental | 24680954 |
DrugRepV_5969 | ZX-2401 | NA | Rhinovirus 1A | Rhinovirus 30 | Rhinovirus 13 | Rhinovirus 8 | Rhinovirus 2 | Dengue virus | New Guinea | | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 16199098 |
DrugRepV_5975 | Deoxynojirimycin | NA | NA | Dengue virus | FGA/89 | | Focus immunoassay | Decrease (80 %) | NA | 10590151 |
DrugRepV_6001 | U18666A | NA | NA | Dengue virus | New Guinea | | Plaque assay | Decrease (3 Log (pfu/ml)) | NA | 22146564 |
DrugRepV_6002 | U18666A | NA | NA | Dengue virus | Replicon systen | | Luciferase reporter assay | Decrease (50 %) | NA | 22146564 |
DrugRepV_6003 | U18666A | NA | NA | Dengue virus | Replicon systen | | Luciferase reporter assay | Decrease (50 %) | NA | 22146564 |
DrugRepV_6006 | Chebulagic Acid | NA | Immunosuppressive and hepatoprotective | Dengue virus | 16681 | | Plaque assay | Decrease (50 %) | NA | 23924316 |
DrugRepV_6008 | Chebulagic Acid | NA | Immunosuppressive and hepatoprotective | Dengue virus | 16681 | | Plaque assay | Decrease (100 %) | NA | 23924316 |
DrugRepV_6013 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | FITC- assay | Decrease (98 %) | NA | 11907199 |
DrugRepV_6014 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Plaque assay | Decrease (4 Log) | NA | 11907199 |
DrugRepV_6015 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Western blot | Decrease (Decrease Band Intensity) | NA | 11907199 |
DrugRepV_6016 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Western blot | Decrease (Decrease Band Intensity) | NA | 11907199 |
DrugRepV_6017 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Real-time PCR | Decrease (Decrease Ct Value) | NA | 11907199 |
DrugRepV_6018 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | PL046 | | Real-time PCR | Decrease (Decrease Ct Value) | NA | 11907199 |
DrugRepV_6038 | 4-(5-(4-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6039 | 4-(5-(2-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6040 | 4-(5-(3-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6041 | 4-(3-Phenyl-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6042 | 4-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6043 | 4-(3-(4-phenoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6044 | 4-(5-(2-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6045 | 4-(5-(3-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6046 | 4-(5-(4-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6047 | 4-(5-(2-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6048 | 4-(5-(3-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6049 | 4-(5-(4-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6050 | 4-(3-(4-phenoxyphenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6051 | 4-(3-(4-phenoxyphenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6052 | 4-(3-(4-phenoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6053 | 4-(3-(4-(benzyloxy)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6054 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6055 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6056 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6057 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6058 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6059 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6060 | 4-(3-(4-(benzyloxy)phenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6061 | 4-(3-(4-(benzyloxy)phenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6062 | 4-(3-(4-(benzyloxy)phenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Dengue virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6064 | N2-(4-fluorophenyl)-N3-(4-methyl-2-(3-methyl-1H-pyrazol- 5-yl)phenyl) pyrazine-2,3 dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6065 | N2-(4-methyl-2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N3-(p- tolyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6066 | N2-(4-fluorophenyl)-N3-(4-methyl-2-(thiophen-2-yl)phenyl) pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6067 | N2-(4-methyl-2-(thiophen-2-yl)phenyl)-N3-(p-tolyl) pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6068 | N2-(4-fluorophenyl)-N3-(4-methyl-2-(5-methylthiophen-2-yl)phenyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6069 | N2-(4-methyl-2-(5-methylthiophen-2-yl)phenyl)-N3-(p- tolyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6070 | N2-(4-fluorophenyl)-N3-(4-methyl-2-(thiophen-3-yl) phenyl)pyrazine-2,3- dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6071 | N2-(4-methyl-2-(thiophen-3-yl)phenyl)-N3-(p-tolyl) pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6072 | N2-(4-fluorophenyl)-N3-(2-(thiophen-3-yl)benzyl)pyrazine- 2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6073 | N2-(2-(thiophen-3-yl)benzyl)-N3-(p-tolyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6074 | N2-(4-fluorophenyl)-N3-(4-(thiophen-3-yl)benzyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6075 | N2-(4-(thiophen-3-yl)benzyl)-N3-(p-tolyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6076 | N2-(4-fluorophenyl)-N3-(2-(3-methyl-1H-pyrazol-5-yl) phenyl)pyrazine-2,3-dicarboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6077 | N2-(2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N3-(p-tolyl) pyrazine-2,3-di-carboxamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6078 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(3-methyl-1H-pyrazol-5-yl)phenyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6079 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(thiophen-2-yl) phenyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6080 | N1-(4-methyl-2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N2-(p- tolyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6081 | N1-(4-methyl-2-(thiophen-2-yl)phenyl)-N2-(p-tolyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6082 | N1-(4-methyl-2-(5-methylthiophen-2-yl)phenyl)-N2-(p- tolyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6083 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(5-methylthiophen-2- yl)phenyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6084 | N1-(4-methyl-2-(thiophen-3-yl)phenyl)-N2-(p-tolyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6085 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(thiophen-3-yl) phenyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6086 | N1-(4-fluorophenyl)-N2-(2-(thiophen-3-yl)benzyl) phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6087 | N1-(2-(thiophen-3-yl)benzyl)-N2-(p-tolyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6088 | N1-(4-fluorophenyl)-N2-(4-(thiophen-3-yl)benzyl) phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6089 | N1-(4-(thiophen-3-yl)benzyl)-N2-(p-tolyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6090 | N1-(4-fluorophenyl)-N2-(2-(3-methyl-1H-pyrazol-5-yl) phenyl)phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6091 | N1-(2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N2-(p-tolyl) phthalamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6092 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(thiophen-3-yl) phenyl)benzamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6093 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(5-methylthiophen- 2-yl)phenyl)benzamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6094 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(pyridin-4-yl)phenyl) benzamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6095 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(pyridin-3-yl)phenyl) benzamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_6097 | SA-3 | NA | NA | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6098 | SA-11 | NA | NA | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6099 | SA-17 | NA | NA | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6100 | SA-17 | NA | NA | Dengue virus | New Guinea C | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6101 | CM-10-18 | NA | NA | Dengue virus | New Guinea C | | MTT assay | Decrease (50 %) | NA | 23578725 |
DrugRepV_6102 | IHVR11029 | NA | NA | Dengue virus | New Guinea C | | MTT assay | Decrease (50 %) | NA | 23578725 |
DrugRepV_6103 | IHVR17028 | NA | NA | Dengue virus | New Guinea C | | MTT assay | Decrease (50 %) | NA | 23578725 |
DrugRepV_6104 | IHVR19029 | NA | NA | Dengue virus | New Guinea C | | MTT assay | Decrease (50 %) | NA | 23578725 |
DrugRepV_6105 | BCX4430 | NA | Ebola virus | Dengue virus | New Guinea C | | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_6106 | IHVR-19029 | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 29253498 |
DrugRepV_6107 | Coumarin A | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (50 %) | NA | 28100218 |
DrugRepV_6108 | Coumarin B | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (50 %) | NA | 28100218 |
DrugRepV_6109 | Lupeol Acetate 26SK001 | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (50 %) | NA | 28100218 |
DrugRepV_6110 | Voacangine 26SK002 | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (50 %) | NA | 28100218 |
DrugRepV_6111 | Coumarin A | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (37.1 %) | NA | 28100218 |
DrugRepV_6112 | Coumarin B | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (99.25 %) | NA | 28100218 |
DrugRepV_6113 | Lupeol Acetate 26SK001 | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (23 %) | NA | 28100218 |
DrugRepV_6114 | Voacangine 26SK002 | NA | NA | Dengue virus | NG | | RT-PCR | Decrease (23 %) | NA | 28100218 |
DrugRepV_6117 | FGI-106 | NA | NA | Dengue virus | NA | | Flow cytometry | Decrease (50 %) | NA | 19523489 |
DrugRepV_6118 | FGI-106 | NA | NA | Dengue virus | NA | | Flow cytometry | Decrease (50 %) | NA | 19523489 |
DrugRepV_6119 | FGI-106 | NA | NA | Dengue virus | NA | | Flow cytometry | Decrease (50 %) | NA | 19523489 |
DrugRepV_6120 | FGI-106 | NA | NA | Dengue virus | NA | | Flow cytometry | Decrease (50 %) | NA | 19523489 |
DrugRepV_6121 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Dengue virus | NA | | Plaque assay | Decrease (50 %) | Investigational | 27889529 |
DrugRepV_6123 | GSK369796 | NA | NA | Dengue virus | NA | | Plaque assay | Decrease (50 %) | NA | 27889529 |
DrugRepV_6124 | Tomatidine | NA | NA | Dengue virus | 16681 | | MTT assay | Decrease (50 %) | NA | 30468746 |
DrugRepV_6125 | Tomatidine | NA | NA | Dengue virus | 16007 | | MTT assay | Decrease (50 %) | NA | 30468746 |
DrugRepV_6126 | Tomatidine | NA | NA | Dengue virus | H87 | | MTT assay | Decrease (50 %) | NA | 30468746 |
DrugRepV_6127 | Tomatidine | NA | NA | Dengue virus | 1036 | | MTT assay | Decrease (50 %) | NA | 30468746 |
DrugRepV_6130 | VGTI-A3 | NA | NA | Dengue virus | New Guinea C | | Focus forming assay | Decrease (90 %) | NA | 29709563 |
DrugRepV_6131 | VGTI-A3-03 | NA | NA | Dengue virus | New Guinea C | | Focus forming assay | Decrease (90 %) | NA | 29709563 |
DrugRepV_6132 | Ribavirin Nucleobase | NA | NA | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6133 | Mizoribine Nucleobase | NA | NA | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6134 | T-1105 | NA | Zika virus | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6135 | Diaminopurine | NA | NA | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6140 | T-1106 | NA | Yellow Fever virus | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6141 | Diaminopurine Riboside | NA | NA | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6142 | T-1105 | NA | Zika virus | Dengue virus | New Guinea C | | Titer reduction assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6143 | T-1106 | NA | Yellow Fever virus | Dengue virus | New Guinea C | | Titer reduction assay | Decrease (50 %) | NA | 29672522 |
DrugRepV_6144 | 5,7-dichloro-2-(propan-2-yl)quinolin-8-ol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 29547522 |
DrugRepV_6145 | 5,7-dichloro-2-(2-methylpropyl)quinolin-8-ol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 29547522 |
DrugRepV_6150 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6151 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6152 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6153 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6154 | Schisandrin A | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 28338050 |
DrugRepV_6155 | Schisandrin B | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 28338050 |
DrugRepV_6156 | Schisandrin C | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 28338050 |
DrugRepV_6157 | Schisandrin A | NA | NA | Dengue virus | NA | | Survival assay | Decrease | NA | 28338050 |
DrugRepV_6160 | 5hydroxyl-6,7,3,4,5-pentamethoxyflavone | NA | NA | Dengue virus | 16681 | | MTT assay | Decrease (50 %) | NA | 22068705 |
DrugRepV_6161 | 5,3-dihydroxy-6,7,4,5-tetramethoxyflavone | NA | NA | Dengue virus | 16681 | | MTT assay | Decrease (50 %) | NA | 22068705 |
DrugRepV_6162 | BZ-TRP-TSC | NA | NA | Dengue virus | NA | | MTT assay | Decrease (85 %) | NA | 27490721 |
DrugRepV_6163 | BZ-TRP-TSC | NA | NA | Dengue virus | NA | | MTT assay | Decrease (76 %) | NA | 27490721 |
DrugRepV_6164 | BZ-TRP-TSC | NA | NA | Dengue virus | NA | | MTT assay | Decrease (65 %) | NA | 27490721 |
DrugRepV_6165 | BZ-TRP-TSC | NA | NA | Dengue virus | NA | | MTT assay | Decrease (76 %) | NA | 27490721 |
DrugRepV_6166 | Thiosemicarbazide | NA | NA | Dengue virus | NA | | Immunoflourescence assay | Decrease | NA | 27490721 |
DrugRepV_6169 | 4-{1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-5-yl}-2-methoxyphenol | NA | NA | Dengue virus | NA | | CPE reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6170 | 4-[1-(4-{[1,1-biphenyl]-4-yl}-1,3-thiazol-2-yl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6171 | 4-[1-(4-{[1,1-biphenyl]-4-yl}-1,3-thiazol-2-yl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-5-yl]-2-methoxyphenol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6172 | 4-[1-(4-{[1,1-biphenyl]-4-yl}-1,3-thiazol-2-yl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-5-yl]phenol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6173 | 4-[(1E)-1-{2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazin-1-ylidene}ethyl]phenol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6174 | 4-{[1,1-biphenyl]-4-yl}-2-[(2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazin-1-yl]-1,3-thiazole | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6175 | 4-{[1,1-biphenyl]-4-yl}-2-[(2E)-2-[1-(4-nitrophenyl)ethylidene]hydrazin-1-yl]-1,3-thiazole | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6176 | 4-{[1,1-biphenyl]-4-yl}-2-[(2E)-2-(phenylmethylidene)hydrazin-1-yl]-1,3-thiazole | NA | NA | Dengue virus | NA | | CPE reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6177 | 4-[(E)-[2-(4-{[1,1-biphenyl]-4-yl}-1,3-thiazol-2-yl)hydrazin-1-ylidene]methyl]phenol | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 25791449 |
DrugRepV_6179 | (1S,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-[(2S,3S,4R,5R,6S)-2,4,5,6,7-pentahydroxy-3-(sulfonatooxy)heptyl]thiolan-1-ium | NA | NA | Dengue virus | ThNH-7/93 | | Fluorescent focus-forming assay | Decrease (50 %) | NA | 22784856 |
DrugRepV_6180 | (1R,2R,3S,4S)-1-[(2S,3S,4R,5R,6S)-2,3,4,5,6,7-hexahydroxyheptyl]-3,4-dihydroxy-2-(hydroxymethyl)thiolan-1-ium chloride | NA | NA | Dengue virus | ThNH-7/93 | | Fluorescent focus-forming assay | Decrease (50 %) | NA | 22784856 |
DrugRepV_6181 | 2 -C-methyladenosine | NA | NA | Dengue virus | New Guinea C (NGC) | | Cell proliferation assay | Decrease (50 %) | NA | 17662475 |
DrugRepV_6184 | UV-4B | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 26946111 |
DrugRepV_6185 | UV-4B | NA | NA | Dengue virus | 16681 | | Virus yield reduction assay | Decrease (50 %) | NA | 26946111 |
DrugRepV_6186 | UV-4B | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 26946111 |
DrugRepV_6187 | UV-4B | NA | NA | Dengue virus | NA | | Virus yield reduction assay | Decrease (50 %) | NA | 26946111 |
DrugRepV_6193 | STK332077 | NA | NA | Dengue virus | New Guinea C (NGC) | | Virus yield reduction assay | Decrease (50 %) | NA | 26807547 |
DrugRepV_6194 | STK529754 | NA | NA | Dengue virus | New Guinea C (NGC) | | Virus yield reduction assay | Decrease (50 %) | NA | 26807547 |
DrugRepV_6195 | STK530661 | NA | NA | Dengue virus | New Guinea C (NGC) | | Virus yield reduction assay | Decrease (50 %) | NA | 26807547 |
DrugRepV_6196 | (2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-acetamido-5-[(prop-1-en-2-yl)amino]pentanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]hexanamido]-N-[(1S)-4-carbamimidamido-1-carbamoylbutyl]hexanamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.31 ± 0.06 Log PFU/ml) | NA | 25823617 |
DrugRepV_6197 | (E)-N-[(E)-({4-[(E)-{[(diaminomethylidene)amino]imino}methyl]phenyl}methylidene)amino]ethanimidamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.37 ± 0.15 Log PFU/ml) | NA | 25823617 |
DrugRepV_6198 | (2S)-6-amino-N-[(1S)-4-carbamimidamido-1-[(5-carbamimidamido-1-oxopentan-2-yl)carbamoyl]butyl]-2-[(2S)-2-(phenylformamido)propanamido]hexanamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.38 ± 0.10 Log PFU/ml) | NA | 25823617 |
DrugRepV_6199 | 7-[(phenylamino)(pyridin-2-yl)methyl]quinolin-8-ol | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.34 ± 0.15 Log PFU/ml) | NA | 25823617 |
DrugRepV_6200 | 1,8-dihydroxy-4,5-dinitro-9,10-dihydroanthracene-9,10-dione | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (50 %) | NA | 25823617 |
DrugRepV_6201 | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.30 ± 0.10 Log PFU/ml) | NA | 25823617 |
DrugRepV_6202 | 4-nitrophenyl 4-carbamimidamidobenzoate | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.41 ± 0.17 Log PFU/ml) | NA | 25823617 |
DrugRepV_6203 | (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.46 ± 0.15 Log PFU/ml) | NA | 25823617 |
DrugRepV_6204 | 4-[2-(2,4-dinitrophenyl)diazen-1-yl]naphthalen-1-ol | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.49 ± 0.26 Log PFU/ml) | NA | 25823617 |
DrugRepV_6205 | 1-ethyl-2-[(1E)-3-[(2Z)-1-ethyl-1H,2H-naphtho[1,2-d][1,3]oxazol-2-ylidene]prop-1-en-1-yl]naphtho[1,2-d][1,3]oxazol-1-ium | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (50 %) | NA | 25823617 |
DrugRepV_6206 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-(phenylformamido)pentanamido]-N-[(1R)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.35 ± 0.21 Log PFU/ml) | NA | 25823617 |
DrugRepV_6207 | (4R,7S,10S,13S,16S,22R)-22-amino-10,16-bis(4-aminobutyl)-13-(3-carbamimidamidopropyl)-7-(hydroxymethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxylic acid | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.46 ± 0.35 Log PFU/ml) | NA | 25823617 |
DrugRepV_6208 | 1-[N-(2-ethylhexyl)carbamimidamido]-N-(6-{N-[N-(2-ethylhexyl)carbamimidoyl]carbamimidamido}hexyl)methanimidamide | NA | NA | Dengue virus | NA | | Cell based assay | Decrease (5.62 ± 0.20 Log PFU/ml) | NA | 25823617 |
DrugRepV_6209 | (1R,2R,4S,5S,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6-[(2S)-butan-2-yl]-21,24-dihydroxy-12-{[(2R,4S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11,13,22-tetramethyl-3,7,19-trioxaspiro[oxane-2,6-tet | NA | NA | Dengue virus | NA | | Cell based assay | Decrease | NA | 25823617 |
DrugRepV_6210 | (1R,2R,4S,5S,6S,8R,10E,13S,14E,16E,20R,21E,24S)-6-cyclohexyl-24-hydroxy-12-{[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-21-(hydroxyimino)-5,11,13,22-tetramethyl-3,7,19-trioxaspiro[oxane-2,6-tetracyclo[15.6.1.14,8.0 | NA | NA | Dengue virus | NA | | Cell based assay | Decrease | NA | 25823617 |
DrugRepV_6221 | 2-chloro-10-(prop-2-en-1-yl)-9,10-dihydroacridin-9-one | NA | NA | Dengue virus | Hawaii | | Virus yield inhibition assay | Decrease (50 %) | NA | 25908170 |
DrugRepV_6222 | 2-chloro-10-(prop-2-en-1-yl)-9,10-dihydroacridin-9-one | NA | NA | Dengue virus | New Guinea C | | Virus yield inhibition assay | Decrease (50 %) | NA | 25908170 |
DrugRepV_6223 | 2-chloro-10-(prop-2-en-1-yl)-9,10-dihydroacridin-9-one | NA | NA | Dengue virus | H87 | | Virus yield inhibition assay | Decrease (50 %) | NA | 25908170 |
DrugRepV_6224 | 2-chloro-10-(prop-2-en-1-yl)-9,10-dihydroacridin-9-one | NA | NA | Dengue virus | 8124 | | Virus yield inhibition assay | Decrease (50 %) | NA | 25908170 |
DrugRepV_6227 | 6-MPTF | NA | NA | Dengue virus | 16681 | | Plaque assay | Decrease (2.05 * 106 pfu/ml) | NA | 7201778 |
DrugRepV_6228 | Sinefungin | NA | NA | Dengue virus | NA | | 2-O-MTase assays | Decrease (50 %) | Experimental | 23769894 |
DrugRepV_6229 | AdoHcy | NA | NA | Dengue virus | NA | | 2-O-MTase assays | Decrease (50 %) | Experimental | 23769894 |
DrugRepV_6230 | Aurintricarboxylic acid | NA | NA | Dengue virus | NA | | 2-O-MTase assays | Decrease (50 %) | NA | 23769894 |
DrugRepV_6231 | 5,50 -Methylene-disalicylic acid | NA | NA | Dengue virus | NA | | 2-O-MTase assays | Decrease (50 %) | NA | 23769894 |
DrugRepV_6232 | YK 51 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (92 %) | NA | 20567498 |
DrugRepV_6233 | YK 73 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (90 %) | NA | 20567498 |
DrugRepV_6234 | YK 73x | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (91 %) | NA | 20567498 |
DrugRepV_6235 | YK 101 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (94 %) | NA | 20567498 |
DrugRepV_6236 | YK 38 | NA | NA | Dengue virus | New Guinea C | | CPE inhibition assay | Decrease (83 %) | NA | 20567498 |
DrugRepV_6237 | YK 38 | NA | NA | Dengue virus | New Guinea C | | Virus plaque assay | Decrease (3.2 * 103 pfu/ml) | NA | 20567498 |
DrugRepV_6238 | YK 51 | NA | NA | Dengue virus | New Guinea C | | Virus plaque assay | Decrease (3.4 * 103 pfu/ml) | NA | 20567498 |
DrugRepV_6239 | YK 73 | NA | NA | Dengue virus | New Guinea C | | Virus plaque assay | Decrease (3.5 * 103 pfu/ml) | NA | 20567498 |
DrugRepV_6240 | YK 73x | NA | NA | Dengue virus | New Guinea C | | Virus plaque assay | Decrease (2.8 * 103 pfu/ml) | NA | 20567498 |
DrugRepV_6241 | YK 101 | NA | NA | Dengue virus | New Guinea C | | Virus plaque assay | Decrease (2.6 * 103 pfu/ml) | NA | 20567498 |
DrugRepV_6242 | 9-benzyl-6-[(1-methyl-4-nitro-4,5-dihydro-1H-imidazol-5-yl)methyl]-9H-purin-2-amine | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6243 | 2-{[(3-nitrophenyl)methyl]sulfanyl}-9H-purin-6-ol | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6244 | 2-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)aniline | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6245 | 1-(4-Bromophenyl)-2-(ethylamino)-2-methylpropyl hydrodisulfide | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6246 | N-[4-(4-aminobenzenesulfonyl)phenyl]pyridine-3-carboxamide | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6247 | 2-(2-{2-[(2E,5E)-3-ethyl-4-oxo-5-[(phenylamino)methylidene]-1,3-thiazolidin-2-ylidene]hydrazin-1-yl}-1,3-thiazol-5-yl)-N-(2-methylphenyl)acetamide | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6248 | (2E)-3-(3,4-dichlorophenyl)-1-[2-(3,5-diphenyl-1H-pyrazol-1-yl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6249 | 2-{[5-(4-{[(4-chlorophenyl)methylidene]amino}phenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(2-nitrophenyl)acetamide | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6250 | 1,3-bis({4-[(1E)-1-(carbamimidamidoimino)ethyl]phenyl})urea | NA | NA | Dengue virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19053243 |
DrugRepV_6251 | 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-4-methyl-4H-1,2,4-triazole | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_6252 | 2-({[5-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,2,4-oxadiazol-3-yl]methyl}sulfanyl)pyridin-1-ium-1-olate | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_6253 | 1-(4-chlorophenyl)-2-({5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-1,3,4-oxadiazol-2-yl}sulfanyl)ethan-1-one | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_6254 | 1-(2-chlorophenyl)-3-{2-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-1,3-thiazol-4-yl}urea | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_6255 | 2-chloro-6-(4-chlorophenoxy)-4-{4-methyl-5-[(1E)-1-(2-phenylhydrazin-1-ylidene)ethyl]-1,3-thiazol-2-yl}pyridine | NA | NA | Dengue virus | NGC | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_6260 | HHA | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6261 | GNA | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6262 | UDA | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6264 | Mannan | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6265 | HHA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6266 | GNA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6267 | UDA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6269 | Mannan | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6270 | HHA | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6271 | GNA | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6272 | UDA | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6274 | Mannan | NA | NA | Dengue virus | New Guinea C (NGC) | | Flow cytometry | Decrease (50 %) | NA | 19264337 |
DrugRepV_6275 | HHA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6276 | GNA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6277 | UDA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6279 | Mannan | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 19264337 |
DrugRepV_6280 | G3d | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6281 | C2S-3 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6283 | DS8000 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6284 | G3d | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6285 | C2S-3 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6287 | DS8000 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6288 | G3d | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6289 | C2S-3 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6291 | DS8000 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6292 | G3d | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6293 | C2S-3 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6295 | DS8000 | NA | NA | Dengue virus | NGC | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6296 | G3d | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6297 | C2S-3 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6299 | DS8000 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6300 | G3d | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6301 | C2S-3 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6303 | DS8000 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6304 | G3d | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6305 | C2S-3 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6307 | DS8000 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6308 | G3d | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6309 | C2S-3 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6311 | DS8000 | NA | NA | Dengue virus | H87 | | Virus yield reduction assay | Decrease (50 %) | NA | 15911027 |
DrugRepV_6313 | PI-88 | NA | Hepatocellular carcinoma | Liver cancer | Melanoma | Multiple myeloma | Dengue virus | NGC | | Flow cytometry | Decrease (53 %) | Investigational | 16309754 |
DrugRepV_6315 | PPS | NA | NA | Dengue virus | NGC | | Flow cytometry | Decrease (76 %) | NA | 16309754 |
DrugRepV_6316 | Lapachaone Alpha | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (98.84 %) | NA | 22155902 |
DrugRepV_6322 | Shikonin | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (78.94 %) | NA | 22155902 |
DrugRepV_6324 | Chelerythrine Chloride | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (73.36 %) | NA | 22155902 |
DrugRepV_6325 | Skimmianine | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (61.96 %) | NA | 22155902 |
DrugRepV_6329 | Tunicamycin B | NA | Bacterial infections | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (55.01 %) | Experimental | 22155902 |
DrugRepV_6330 | Acivicin | NA | Cancer | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (54.32 %) | Phase I | 22155902 |
DrugRepV_6334 | Gitoxigenin | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (49.01 %) | NA | 22155902 |
DrugRepV_6335 | Kainic acid | NA | Neuroexcitatory | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (48.87 %) | NA | 22155902 |
DrugRepV_6338 | Diacetoxyscirpenol | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (45.55 %) | NA | 22155902 |
DrugRepV_6339 | Austricin | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (45.01 %) | NA | 22155902 |
DrugRepV_6340 | Valinomycin | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (43.34 %) | Experimental | 22155902 |
DrugRepV_6341 | Thapsigargin | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (42.9 %) | NA | 22155902 |
DrugRepV_6344 | Echinomycin | NA | Bacterial infections | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (41.52 %) | NA | 22155902 |
DrugRepV_6345 | Chromomycin A3 | NA | NA | Dengue virus | New Guinea C | | Immunoflourescence assay | Decrease (40.87 %) | NA | 22155902 |
DrugRepV_6346 | AM404 | NA | Pain and Fever | Dengue virus | New Guinea C (NGC) | | NA | Decrease (50 %) | Phase IV | 26856827 |
DrugRepV_6349 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-butyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6350 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclopentyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6351 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclohexyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6352 | methyl 2-[(5Z)-5-[(4-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-carbamoylpentyl]carbamoyl}pentyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}phenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoate | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6353 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6354 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-methylphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6355 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6356 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-fluorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6357 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-chlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6358 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6359 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-butyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6360 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclopentyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6361 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclohexyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6362 | 2-[(5Z)-5-[(4-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-carbamoylpentyl]carbamoyl}pentyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}phenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl acetate | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6363 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6364 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-methylphenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6365 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6366 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6367 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-chlorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6368 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-2,4-dioxo-3-(2-phenylethyl)-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6369 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-6,7-dioxo-8-(phenylformamido)undecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6370 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-6,7-dioxo-8-[(thiophen-2-yl)formamido]undecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6371 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-({4-[(1E)-2-cyano-2-(cyclopropylcarbamoyl)eth-1-en-1-yl]phenyl}formamido)-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6372 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-({4-[(1E)-2-carbamoyleth-1-en-1-yl]phenyl}formamido)-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6373 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-6,7-dioxo-8-[(2E)-3-phenylprop-2-enamido]undecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Protease Assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6374 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6375 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-methyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6376 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-butyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6377 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclopentyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6378 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclohexyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6379 | methyl 2-[(5Z)-5-[(4-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-carbamoylpentyl]carbamoyl}pentyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}phenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]hexanoate | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6380 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-3-(prop-2-en-1-yl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6381 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(2-hydroxyethyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6382 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(4-methoxyphenyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6383 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(4-chlorophenyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6384 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6385 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-chlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6386 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6387 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6388 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-butyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6389 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-cyclopentyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6390 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-(2-hydroxyethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6391 | (2S)-6-amino-2-[(2S)-2-[(4-{[(5Z)-3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-5-carbamimidamidopentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6392 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-3-[(4-chlorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6393 | (2S)-6-amino-2-[(2S)-5-carbamimidamido-2-[(4-{[(5Z)-2,4-dioxo-3-(2-phenylethyl)-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]pentanamido]-N-[(1S)-1-carbamoylpentyl]hexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6394 | (2S)-N-[(4S,7S)-1-amino-7-{[1-(4-{[(5Z)-3-benzyl-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenyl)ethenyl]amino}-10-carbamimidamido-5,6-dioxodecan-4-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6395 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-6,7-dioxo-8-[(3-{[(5Z)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]undecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6396 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-[(3-{[(5Z)-3-cyclopentyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}phenyl)formamido]-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6397 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-[(2S)-2-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanamido]-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6398 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-(2-{3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-yl}acetamido)-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6399 | (2S)-N-[(5S,8S)-1-amino-11-carbamimidamido-8-{2-[(5Z)-3-[(4-methoxyphenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]acetamido}-6,7-dioxoundecan-5-yl]-2-hydrazinylhexanamide | NA | NA | Dengue virus | NA | | Renilla luciferase assay | Decrease (50 %) | NA | 24083834 |
DrugRepV_6400 | HHA | NA | NA | Dengue virus | D1/H/IMTSSA/98/606 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6401 | HHA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6402 | HHA | NA | NA | Dengue virus | H87 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6403 | HHA | NA | NA | Dengue virus | Dak HD 34 460 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6404 | HHA | NA | NA | Dengue virus | D1/H/IMTSSA/98/606 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6405 | HHA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6406 | HHA | NA | NA | Dengue virus | H87 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6407 | HHA | NA | NA | Dengue virus | Dak HD 34 460 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6408 | GNA | NA | NA | Dengue virus | D1/H/IMTSSA/98/606 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6409 | GNA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6410 | GNA | NA | NA | Dengue virus | H87 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6411 | GNA | NA | NA | Dengue virus | Dak HD 34 460 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6412 | GNA | NA | NA | Dengue virus | D1/H/IMTSSA/98/606 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6413 | GNA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6414 | GNA | NA | NA | Dengue virus | H87 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6415 | GNA | NA | NA | Dengue virus | Dak HD 34 460 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6416 | UDA | NA | NA | Dengue virus | D1/H/IMTSSA/98/606 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6417 | UDA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6418 | UDA | NA | NA | Dengue virus | H87 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6419 | UDA | NA | NA | Dengue virus | Dak HD 34 460 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6420 | UDA | NA | NA | Dengue virus | D1/H/IMTSSA/98/606 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6421 | UDA | NA | NA | Dengue virus | New Guinea C (NGC) | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6422 | UDA | NA | NA | Dengue virus | H87 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6423 | UDA | NA | NA | Dengue virus | Dak HD 34 460 | | RT-PCR | Decrease (50 %) | NA | 21738755 |
DrugRepV_6424 | Carbenoxolone disodium | NA | Digestive tract ulcers | Dengue virus | Hawaii | | TCID50 assay | Decrease (500 Fold) | Experimental | 27155198 |
DrugRepV_6425 | Carbenoxolone disodium | NA | Digestive tract ulcers | Dengue virus | New Guinea C | | TCID50 assay | Decrease (2000 Fold) | Experimental | 27155198 |
DrugRepV_6426 | Cdt yellow | NA | NA | Dengue virus | NGC | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_6427 | Cdt white | NA | NA | Dengue virus | NGC | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_6428 | Crotoxin | NA | NA | Dengue virus | NGC | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_6429 | Crotapotin | NA | NA | Dengue virus | NGC | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_6430 | Crotamin | NA | NA | Dengue virus | NGC | | NA | Decrease (11 %) | NA | 21723310 |
DrugRepV_6431 | Convulxin | NA | NA | Dengue virus | NGC | | NA | Decrease (5 %) | NA | 21723310 |
DrugRepV_6432 | PLA2-IC | NA | NA | Dengue virus | NGC | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_6433 | PLA2-IC | NA | NA | Dengue virus | NGC | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_6434 | Cdt yellow | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6435 | Cdt white | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6436 | Crotoxin | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6437 | Crotapotin | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6438 | Crotamin | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (33 %) | NA | 21723310 |
DrugRepV_6439 | Convulxin | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (32 %) | NA | 21723310 |
DrugRepV_6440 | PLA2-IC | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6441 | PLA2-IC | NA | NA | Dengue virus | NGC | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6442 | Cdt yellow | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6443 | Cdt white | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6444 | Crotoxin | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6445 | Crotapotin | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6446 | Crotamin | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (100 %) | NA | 21723310 |
DrugRepV_6447 | Convulxin | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (100 %) | NA | 21723310 |
DrugRepV_6448 | PLA2-IC | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6449 | PLA2-IC | NA | NA | Dengue virus | NGC | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6450 | Cdt yellow | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6451 | Cdt white | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6452 | Crotoxin | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6453 | Crotapotin | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (41 %) | NA | 21723310 |
DrugRepV_6454 | Crotamin | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (46 %) | NA | 21723310 |
DrugRepV_6455 | Convulxin | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (2.3 %) | NA | 21723310 |
DrugRepV_6456 | PLA2-IC | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6457 | PLA2-IC | NA | NA | Dengue virus | NGC | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_6458 | (3E)-N-tert-butyl-2-oxo-4-phenylbut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (26.3 %) | NA | 21641807 |
DrugRepV_6459 | (3E)-N-tert-butyl-3-methyl-2-oxo-4-phenylbut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (25.6 %) | NA | 21641807 |
DrugRepV_6460 | (3E)-N-tert-butyl-2-oxo-4-(thiophen-2-yl)but-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (27.6 %) | NA | 21641807 |
DrugRepV_6461 | (3E)-N-tert-butyl-4-(4-methoxyphenyl)-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (16.7 %) | NA | 21641807 |
DrugRepV_6462 | (3E)-N-tert-butyl-4-(3,4-dimethoxyphenyl)-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (36.1 %) | NA | 21641807 |
DrugRepV_6463 | (3E)-N-tert-butyl-4-(4-hydroxyphenyl)-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (37.6 %) | NA | 21641807 |
DrugRepV_6464 | (3E)-4-(4-aminophenyl)-N-tert-butyl-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (40.6 %) | NA | 21641807 |
DrugRepV_6465 | (3E)-N-tert-butyl-4-(4-chlorophenyl)-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (15.9 %) | NA | 21641807 |
DrugRepV_6466 | (3E)-N-tert-butyl-4-(1H-indol-3-yl)-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (39.1 %) | NA | 21641807 |
DrugRepV_6467 | (3E)-N-tert-butyl-4-[4-(dimethylamino)phenyl]-2-oxobut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (13.8 %) | NA | 21641807 |
DrugRepV_6468 | (3E)-N-cyclopropyl-2-oxo-4-phenylbut-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (31.2 %) | NA | 21641807 |
DrugRepV_6469 | 2-[(3E)-2-oxo-4-phenylbut-3-enamido]ethyl acetate | NA | NA | Dengue virus | NA | | Protease assay | Decrease (35.8 %) | NA | 21641807 |
DrugRepV_6470 | (3E)-2-oxo-4-phenyl-N-(1-phenylethyl)but-3-enamide | NA | NA | Dengue virus | NA | | Protease assay | Decrease (0 %) | NA | 21641807 |
DrugRepV_6471 | methyl 3-hydroxy-2-[(3E)-2-oxo-4-phenylbut-3-enamido]propanoate | NA | NA | Dengue virus | NA | | Protease assay | Decrease (35.1 %) | NA | 21641807 |
DrugRepV_6472 | Delphinidin Chloride | NA | NA | Dengue virus | NA | | Plaque assay | Decrease | NA | 28744282 |
DrugRepV_6474 | N-nonyl-deoxynojirimycin | NA | NA | Dengue virus | New Guinea C | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_6475 | N-pentyl-(1-hydroxycyclohexyl)-DNJ | NA | NA | Dengue virus | New Guinea C | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_6476 | N-Propylcyclohexyl-DNJ | NA | NA | Dengue virus | New Guinea C | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_6477 | N-Butylcyclohexyl-DNJ | NA | NA | Dengue virus | New Guinea C | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_6479 | N-acetyl cysteine | NA | Acetaminophen poisoning | Dengue virus | NA | | Cell viability assay | Decrease (50 %) | Approved | 30928439 |
DrugRepV_6480 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Dengue virus | NA | | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_6487 | KX2-391 | NA | Colon cancer | Pancreatic cancer | Prostate cancer | Breast cancer | Human immunodeficiency virus | HXB2 luciferase reporter virus | | Luciferase reporter assay | Decrease (80 %) | Investigational | 26807966 |
DrugRepV_6488 | KX2-391 | NA | Colon cancer | Pancreatic cancer | Prostate cancer | Breast cancer | Human immunodeficiency virus | JR-FL luciferase reporter virus | | Luciferase reporter assay | Decrease (90 %) | Investigational | 26807966 |
DrugRepV_6496 | Decitabine | NA | Myelodysplastic syndromes +Different types of Cancer | Human immunodeficiency virus | NA | | Plaque assay | Decrease (73 %) | NA | 20610712 |
DrugRepV_6498 | Decitabine | NA | NA | Human immunodeficiency virus | NA | | Plaque assay | Decrease (75 %) | NA | 20610712 |
DrugRepV_6500 | Decitabine | NA | Myelodysplastic syndromes +Different types of Cancer | Human immunodeficiency virus | NA | | Real-time PCR | Decrease | NA | 20610712 |
DrugRepV_6867 | 4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6868 | 4-(5-(2-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6869 | 4-(5-(3-fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6870 | 4-(5-(4-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6871 | 4-(5-(2-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6872 | 4-(5-(3-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6873 | 4-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6874 | 4-(3-Phenyl-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6875 | 4-(3-Phenyl-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6876 | 4-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6877 | 4-(3-(4-phenoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6878 | 4-(5-(2-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6879 | 4-(5-(3-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6880 | 4-(5-(4-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6881 | 4-(5-(2-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6882 | 4-(5-(3-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6883 | 4-(5-(4-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6884 | 4-(3-(4-phenoxyphenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6885 | 4-(3-(4-phenoxyphenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6886 | 4-(3-(4-phenoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6887 | 4-(3-(4-(benzyloxy)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6888 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6889 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6890 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6891 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6892 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6893 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6894 | 4-(3-(4-(benzyloxy)phenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6895 | 4-(3-(4-(benzyloxy)phenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6896 | 4-(3-(4-(benzyloxy)phenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Human immunodeficiency virus | NA | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_6897 | Phorbol | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6898 | Phorbol-12-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6899 | Phorbol-12-decanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6900 | Phorbol-13-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6901 | Phorbol-13-butyrate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6902 | Phorbol-13-decanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6903 | Phorbol-13-tetradecanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6904 | Phorbol-12,13-diacetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6905 | Phorbol-12,13-dibutyrate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6906 | Phorbol-12,13- dihexanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6907 | Phorbol-12,13-didecanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6908 | 4α-phorbol-12,13-didecanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6909 | 12-O-tetradecanoylphorbol-13-acetate | NA | Cancer | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | Phase II | 25970561 |
DrugRepV_6910 | 12-O-tetradecanoyl-4γ-phorbol-13-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6911 | 12-O- tiglylphorbol-13-decanoate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6912 | 12-O-(N-methylanthranilate) phorbol-13-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6913 | Phorbol-13,20-diacetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6914 | 12,13-O,O-dinonanoylphorbol-20-homovanillate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6915 | 12-O-phenylacetyl-13-O-acetylphorbol-20-homovanillate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6916 | Phorbol-12,13,20-triacetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6917 | 20-oxo-20-deoxyphorbol-12,13-dibutyrate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6918 | 12-O-tetradecanoyl-20-oxo-20-deoxyphorbol-13-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6919 | 12-deoxyphorbol-13-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6920 | 13-O-isobutyryl-12-deoxyphorbol-20-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6921 | 13-O-phenylacetyl-12-deoxyphorbol-20-acetate | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6925 | Resiniferatoxin | NA | Interstitial cystitis and urinary incontinence | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | Investigational | 25970561 |
DrugRepV_6927 | Phorbol | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6928 | Phorbol-12-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6929 | Phorbol-12-decanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6930 | Phorbol-13-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6931 | Phorbol-13-butyrate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6932 | Pphorbol-13-decanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6933 | Phorbol-13-tetradecanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6934 | Phorbol-12,13-diacetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6935 | Phorbol-12,13-dibutyrate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6936 | Phorbol-12,13- dihexanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6937 | Phorbol-12,13-didecanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6938 | 4α-phorbol-12,13-didecanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6939 | 12-O-tetradecanoylphorbol-13-acetate | NA | Cancer | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | Phase II | 25970561 |
DrugRepV_6940 | 12-O-tetradecanoyl-4?-phorbol-13-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6941 | 12-O- tiglylphorbol-13-decanoate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6942 | 12-O-(N-methylanthranilate) phorbol-13-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6943 | Phorbol-13,20-diacetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6944 | 12,13-O,O-dinonanoylphorbol-20-homovanillate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6945 | 12-O-phenylacetyl-13-O-acetylphorbol-20-homovanillate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6946 | Phorbol-12,13,20-triacetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6947 | 20-oxo-20-deoxyphorbol-12,13-dibutyrate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6948 | 12-O-tetradecanoyl-20-oxo-20-deoxyphorbol-13-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6949 | 12-deoxyphorbol-13-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6950 | 13-O-isobutyryl-12-deoxyphorbol-20-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6951 | 13-O-phenylacetyl-12-deoxyphorbol-20-acetate | NA | NA | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | NA | 25970561 |
DrugRepV_6955 | Resiniferatoxin | NA | Interstitial cystitis and urinary incontinence | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | Investigational | 25970561 |
DrugRepV_6957 | FGI-106 | NA | NA | Human immunodeficiency virus | NA | | Luciferase assay | Decrease (50 %) | NA | 19523489 |
DrugRepV_6964 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6965 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]thymine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6966 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorouracil | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6967 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]cytosine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6968 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorocytosine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6969 | L-Neplanocin A | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6970 | (1S,2R,3S)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl] hypoxanthine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6971 | (1S,2R,3S)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]guanine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6972 | Cyclopentenyl nucleosides | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6973 | (1R,2S,3R)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl] hypoxanthine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6974 | (1R,2S,3R)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]guanine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6975 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6976 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]thymine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6977 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorouracil | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6978 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]cytosine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6979 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorocytosine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 11689085 |
DrugRepV_6980 | Octadecyloxyethyl benzyl 9-[(2-phosphonomethoxy)ethyl]guanine | NA | NA | Human immunodeficiency virus | NA | | RT-PCR | Decrease (50 %) | NA | 27933957 |
DrugRepV_6981 | 3-azido-2,3-dideoxyuridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6982 | 1-(4-azido-5-hydroxyoxolan-2-yl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6983 | 1-(4-azido-5-hydroxyoxolan-2-yl)-5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6984 | 2- deoxy-5-fluorouridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6985 | 2- deoxy-5-bromouridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6986 | 2-deoxy-5-iodouridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6987 | 3-Azido-2,3-dideoxy-5-aminouridine Hydrochloride | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6988 | 3-Azido-2,3-dideoxy-5-(methylamino)uridine hydrochloride | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6989 | 3-Azido-2,3-dideoxy-5-(dimethylamino)uridine hydrochloride | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6990 | 3-Azido-2,3-dideoxy-5-hydroxyuridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6991 | 3-Azido-2,3-dideoxy-5-methoxyuridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6992 | 3-Azido-2,3-dideoxy-5-ethoxyuridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6993 | 3-Azido-2,3-dideoxy-5-(2-propynyloxy)uridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6994 | 3-Azido-2,3-dideoxy-5-(propenyloxy)uridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6995 | 3-Azido-2,3-dideoxy-5-[(cyanomethyl)oxy]uridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6996 | 3-Azido-2,3-dideoxy-5-thiocyanatouridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6997 | 3-Azido-2,3-dideoxy-5-(methylthio)uridine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6998 | 2-deoxycytidine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_6999 | 2-deoxy-5-fluorocytidine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_7000 | 2,-deoxy-5-methylcytidine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_7001 | 3-(3-Oxo-l-propenyI)-3-azido-3-deoxyThymidine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_7002 | 3-Azido-3-deoxy-6-azaThymidine | NA | NA | Human immunodeficiency virus | LAV | | RT assay | Decrease (50 %) | NA | 3339606 |
DrugRepV_7047 | 2-Aminobiphenyl borate | NA | NA | Japanese encephalitis virus | AT31 | | Immunoflourescence assay | Decrease (18 %) | NA | 28814523 |
DrugRepV_7049 | 1,2-bis-(o-aminophenoxy)-ethane-N,N,N,N-tetraacetic Acid | NA | NA | Japanese encephalitis virus | AT31 | | Immunoflourescence assay | Decrease (60 %) | NA | 28814523 |
DrugRepV_7051 | 2-Aminobiphenyl borate | NA | NA | Japanese encephalitis virus | AT31 | | Immunoflourescence assay | Decrease (20 %) | NA | 28814523 |
DrugRepV_7053 | 1,2-bis-(o-aminophenoxy)-ethane-N,N,N,N-tetraacetic Acid | NA | NA | Japanese encephalitis virus | AT31 | | Immunoflourescence assay | Decrease (45 %) | NA | 28814523 |
DrugRepV_7068 | Quinacrine Mustard | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | West Nile virus | NA | | Plaque assay | Decrease (> 99 %) | Experimental | 24680954 |
DrugRepV_7086 | Quinacrine Mustard | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | West Nile virus | NA | | Plaque assay | Decrease (50 %) | Experimental | 24680954 |
DrugRepV_7097 | Abamectin | NA | Helmintic infection | Yellow fever virus | 17D | | Plaque assay | Decrease (5.3 Log) | Terminated | 26752081 |
DrugRepV_7098 | Berberine | NA | Parasitic and fungal infection | Yellow fever virus | 17D | | Plaque assay | No significant effect (No significant effect Log) | Approved | 26752081 |
DrugRepV_7103 | Chebulagic Acid | NA | Immunosuppressive and hepatoprotective | Measles virus | IC323 | | EGFP assay | Decrease (50 %) | NA | 23924316 |
DrugRepV_7105 | Chebulagic Acid | NA | Immunosuppressive and hepatoprotective | Measles virus | IC323 | | EGFP assay | Decrease (80 %) | NA | 23924316 |
DrugRepV_7107 | Arbidol | NA | Viral infection | Polio virus | NA | | Plaque assay | Decrease (50 %) | Phase IV | 22028179 |
DrugRepV_7108 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Immunoflourescence assay | Decrease (90 %) | NA | 11907199 |
DrugRepV_7109 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Plaque assay | Decrease (3 Logs) | NA | 11907199 |
DrugRepV_7110 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | LDH assay | No significant effect | NA | 11907199 |
DrugRepV_7111 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Western blot | No significant effect (No significant effect Band Intensity) | NA | 11907199 |
DrugRepV_7112 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Western blot | No significant effect (No significant effect Band Intensity) | NA | 11907199 |
DrugRepV_7113 | N-nonyl-deoxynojirimycin | NA | NA | Japanese encephalitis virus | RP-9 | | Survival assay | Increase | NA | 11907199 |
DrugRepV_7115 | 4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7116 | 4-(5-(2-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7117 | 4-(5-(3-fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7118 | 4-(5-(4-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7119 | 4-(5-(2-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7120 | 4-(5-(3-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7121 | 4-(5-(4-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7122 | 4-(3-Phenyl-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7123 | 4-(3-Phenyl-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7124 | 4-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7125 | 4-(3-(4-phenoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7126 | 4-(5-(2-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7127 | 4-(5-(3-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7128 | 4-(5-(4-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7129 | 4-(5-(2-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7130 | 4-(5-(3-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7131 | 4-(5-(4-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7132 | 4-(3-(4-phenoxyphenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7133 | 4-(3-(4-phenoxyphenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7134 | 4-(3-(4-phenoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7135 | 4-(3-(4-(benzyloxy)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7136 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7137 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7138 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7139 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7140 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7141 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7142 | 4-(3-(4-(benzyloxy)phenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7143 | 4-(3-(4-(benzyloxy)phenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7144 | 4-(3-(4-(benzyloxy)phenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | Yellow fever virus | 17D | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7145 | 4-(5-(4-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7146 | 4-(5-(2-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7147 | 4-(5-(3-chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7148 | 4-(3-Phenyl-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7149 | 4-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7150 | 4-(3-(4-phenoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7151 | 4-(5-(2-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7152 | 4-(5-(3-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7153 | 4-(5-(4-fluorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7154 | 4-(5-(2-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7155 | 4-(5-(3-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7156 | 4-(5-(4-chlorophenyl)-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7157 | 4-(3-(4-phenoxyphenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7158 | 4-(3-(4-phenoxyphenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7159 | 4-(3-(4-phenoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7160 | 4-(3-(4-(benzyloxy)phenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7161 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7162 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7163 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7164 | 4-(3-(4-(benzyloxy)phenyl)-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7165 | 4-(3-(4-(benzyloxy)phenyl)-5-(3-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7166 | 4-(3-(4-(benzyloxy)phenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7167 | 4-(3-(4-(benzyloxy)phenyl)-5-(o-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7168 | 4-(3-(4-(benzyloxy)phenyl)-5-(m-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7169 | 4-(3-(4-(benzyloxy)phenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1- yl)benzenesulfonamide | NA | NA | West Nile virus | Clinical isolate | | MTT assay | Decrease (50 %) | NA | 29028528 |
DrugRepV_7173 | N2-(4-fluorophenyl)-N3-(4-methyl-2-(thiophen-2-yl)phenyl) pyrazine-2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7174 | N2-(4-fluorophenyl)-N3-(4-methyl-2-(thiophen-3-yl) phenyl)pyrazine-2,3- dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7175 | N2-(4-methyl-2-(thiophen-3-yl)phenyl)-N3-(p-tolyl) pyrazine-2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7176 | N2-(4-fluorophenyl)-N3-(2-(thiophen-3-yl)benzyl)pyrazine- 2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7177 | N2-(2-(thiophen-3-yl)benzyl)-N3-(p-tolyl)pyrazine-2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7178 | N2-(4-fluorophenyl)-N3-(4-(thiophen-3-yl)benzyl)pyrazine-2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7179 | N2-(4-(thiophen-3-yl)benzyl)-N3-(p-tolyl)pyrazine-2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7180 | N2-(4-fluorophenyl)-N3-(2-(3-methyl-1H-pyrazol-5-yl) phenyl)pyrazine-2,3-dicarboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7181 | N2-(2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N3-(p-tolyl) pyrazine-2,3-di-carboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7182 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(3-methyl-1H-pyrazol-5-yl)phenyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7183 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(thiophen-2-yl) phenyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7184 | N1-(4-methyl-2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N2-(p- tolyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7185 | N1-(4-methyl-2-(thiophen-2-yl)phenyl)-N2-(p-tolyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7186 | N1-(4-methyl-2-(5-methylthiophen-2-yl)phenyl)-N2-(p- tolyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7187 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(5-methylthiophen-2- yl)phenyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7188 | N1-(4-methyl-2-(thiophen-3-yl)phenyl)-N2-(p-tolyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7189 | N1-(4-fluorophenyl)-N2-(4-methyl-2-(thiophen-3-yl) phenyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7190 | N1-(4-fluorophenyl)-N2-(2-(thiophen-3-yl)benzyl) phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7191 | N1-(2-(thiophen-3-yl)benzyl)-N2-(p-tolyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7192 | N1-(4-fluorophenyl)-N2-(4-(thiophen-3-yl)benzyl) phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7193 | N1-(4-(thiophen-3-yl)benzyl)-N2-(p-tolyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7194 | N1-(4-fluorophenyl)-N2-(2-(3-methyl-1H-pyrazol-5-yl) phenyl)phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7195 | N1-(2-(3-methyl-1H-pyrazol-5-yl)phenyl)-N2-(p-tolyl) phthalamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7196 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(thiophen-3-yl) phenyl)benzamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7197 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(5-methylthiophen- 2-yl)phenyl)benzamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7198 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(pyridin-4-yl)phenyl) benzamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7199 | 2-(4-fluorobenzamido)-N-(4-methyl-2-(pyridin-3-yl)phenyl) benzamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 27240271 |
DrugRepV_7200 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | HTS assay | Decrease (50 %) | NA | 19651907 |
DrugRepV_7201 | CCG-3394 | NA | NA | Yellow fever virus | YFV 17D | | HTS assay | Decrease (50 %) | NA | 19651907 |
DrugRepV_7202 | CCG-3925 | NA | NA | Yellow fever virus | YFV 17D | | HTS assay | Decrease (50 %) | NA | 19651907 |
DrugRepV_7203 | CCG-7648 | NA | NA | Yellow fever virus | YFV 17D | | HTS assay | Decrease (50 %) | NA | 19651907 |
DrugRepV_7204 | CCG-6269 | NA | NA | Yellow fever virus | YFV 17D | | HTS assay | Decrease (50 %) | NA | 19651907 |
DrugRepV_7205 | CCG-3374 | NA | NA | Yellow fever virus | YFV 17D | | HTS assay | Decrease (50 %) | NA | 19651907 |
DrugRepV_7206 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | qRT-PCR | Decrease (20 Fold) | NA | 19651907 |
DrugRepV_7207 | CCG-3394 | NA | NA | Yellow fever virus | YFV 17D | | qRT-PCR | Decrease (15 Fold) | NA | 19651907 |
DrugRepV_7208 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | Immunoflourescence assay | Decrease | NA | 19651907 |
DrugRepV_7209 | CCG-3394 | NA | NA | Yellow fever virus | YFV 17D | | Immunoflourescence assay | Decrease | NA | 19651907 |
DrugRepV_7210 | CCG-6269 | NA | NA | Yellow fever virus | YFV 17D | | Luciferase assay | Decrease (87 %) | NA | 19651907 |
DrugRepV_7211 | CCG-3394 | NA | NA | Yellow fever virus | YFV 17D | | Luciferase assay | Decrease (92 %) | NA | 19651907 |
DrugRepV_7212 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | Luciferase assay | Decrease (90 %) | NA | 19651907 |
DrugRepV_7213 | CCG-3394 | NA | NA | Yellow fever virus | YFV 17D | | Luciferase assay | Decrease (38 %) | NA | 19651907 |
DrugRepV_7214 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | Luciferase assay | Decrease (48 %) | NA | 19651907 |
DrugRepV_7215 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | Luciferase assay | Decrease (42 %) | NA | 19651907 |
DrugRepV_7217 | SA-3 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7218 | SA-11 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7219 | SA-17 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7220 | SA-17 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7221 | 2-(3-chlorophenoxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Plaque reduction assay | Decrease (60 %) | NA | 28068627 |
DrugRepV_7222 | 2-(3,4-dichlorophen oxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Plaque reduction assay | Decrease (78 %) | NA | 28068627 |
DrugRepV_7223 | 2-(2,3-dichlorophenoxy) acetaldehyde thiosemicarbazone | NA | NA | Yellow fever virus | NA | | Plaque reduction assay | Decrease (70 %) | NA | 28068627 |
DrugRepV_7224 | 2-(4-(4-fluorophenyl)thiazol-2-yl)hydrazono)ethyl)isoindoline-1,3-dione | NA | NA | Yellow fever virus | NA | | Plaque reduction assay | Decrease (40 %) | NA | 28068627 |
DrugRepV_7225 | 2-(4-(4-chlorophenyl) thiazol-2-yl)hydrazono)ethyl)isoindoline-1,3-dione | NA | NA | Yellow fever virus | NA | | Plaque reduction assay | Decrease (55 %) | NA | 28068627 |
DrugRepV_7226 | 2-(3-chlorophenoxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Flow cytometry | Decrease (17 %) | NA | 28068627 |
DrugRepV_7227 | 2-(3,4-dichlorophen oxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Flow cytometry | Decrease (22 %) | NA | 28068627 |
DrugRepV_7228 | 2-(2,3-dichlorophenoxy) acetaldehyde thiosemicarbazone | NA | NA | Yellow fever virus | NA | | Flow cytometry | Decrease (14 %) | NA | 28068627 |
DrugRepV_7229 | 2-(4-(4-fluorophenyl)thiazol-2-yl)hydrazono)ethyl)isoindoline-1,3-dione | NA | NA | Yellow fever virus | NA | | Flow cytometry | Decrease (10 %) | NA | 28068627 |
DrugRepV_7230 | 2-(4-(4-chlorophenyl) thiazol-2-yl)hydrazono)ethyl)isoindoline-1,3-dione | NA | NA | Yellow fever virus | NA | | Flow cytometry | Decrease (3 %) | NA | 28068627 |
DrugRepV_7231 | 2-(3-chlorophenoxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Flow cytometry | Increase | NA | 28068627 |
DrugRepV_7232 | 2-(3,4-dichlorophen oxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Flow cytometry | Increase | NA | 28068627 |
DrugRepV_7233 | 2-(2,3-dichlorophenoxy) acetaldehyde thiosemicarbazone | NA | NA | Yellow fever virus | NA | | Flow cytometry | Increase | NA | 28068627 |
DrugRepV_7234 | 2-(4-(4-fluorophenyl)thiazol-2-yl)hydrazono)ethyl)isoindoline-1,3-dione | NA | NA | Yellow fever virus | NA | | Flow cytometry | Increase | NA | 28068627 |
DrugRepV_7235 | 2-(4-(4-chlorophenyl) thiazol-2-yl)hydrazono)ethyl)isoindoline-1,3-dione | NA | NA | Yellow fever virus | NA | | Flow cytometry | Increase | NA | 28068627 |
DrugRepV_7236 | 2-(3-chlorophenoxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Immunoflourescence assay | Decrease | NA | 28068627 |
DrugRepV_7237 | 2-(3,4-dichlorophen oxy) acetaldehydethiosemicarbazone | NA | NA | Yellow fever virus | NA | | Immunoflourescence assay | Decrease | NA | 28068627 |
DrugRepV_7238 | BCX4430 | NA | Ebola virus | Measles virus | Chicago | | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_7239 | BCX4430 | NA | Ebola virus | Yellow fever virus | 17D | | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_7240 | BCX4430 | NA | Ebola virus | Japanese encephalitis virus | SA14 | | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_7242 | IHVR-19029 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 29253498 |
DrugRepV_7243 | BCX4430 | NA | Ebola virus | Yellow fever virus | 17D | | NA | Decrease (50 %) | Investigational | 27095300 |
DrugRepV_7244 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-1,2,4-triazole-3-carboxamide | NA | NA | West Nile virus | NA | | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_7245 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-1,2,4-triazole-3-carboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_7246 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-imidazole-4-carboxamide | NA | NA | West Nile virus | NA | | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_7247 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-imidazole-4-carboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_7248 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-1,2,3-triazole-4-carboxamide | NA | NA | West Nile virus | NA | | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_7249 | 1-[4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]-1H-1,2,3-triazole-4-carboxamide | NA | NA | Yellow fever virus | NA | | NA | Decrease (50 %) | NA | 16451078 |
DrugRepV_7251 | 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-4-methyl-4H-1,2,4-triazole | NA | NA | West Nile virus | Kunjin | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7252 | 2-({[5-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,2,4-oxadiazol-3-yl]methyl}sulfanyl)pyridin-1-ium-1-olate | NA | NA | West Nile virus | Kunjin | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7253 | 1-(4-chlorophenyl)-2-({5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-1,3,4-oxadiazol-2-yl}sulfanyl)ethan-1-one | NA | NA | West Nile virus | Kunjin | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7254 | 1-(2-chlorophenyl)-3-{2-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-1,3-thiazol-4-yl}urea | NA | NA | West Nile virus | Kunjin | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7255 | 2-chloro-6-(4-chlorophenoxy)-4-{4-methyl-5-[(1E)-1-(2-phenylhydrazin-1-ylidene)ethyl]-1,3-thiazol-2-yl}pyridine | NA | NA | West Nile virus | Kunjin | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7256 | 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-4-methyl-4H-1,2,4-triazole | NA | NA | Yellow fever virus | 17D | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7257 | 2-({[5-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-1,2,4-oxadiazol-3-yl]methyl}sulfanyl)pyridin-1-ium-1-olate | NA | NA | Yellow fever virus | 17D | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7258 | 1-(4-chlorophenyl)-2-({5-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-1,3,4-oxadiazol-2-yl}sulfanyl)ethan-1-one | NA | NA | Yellow fever virus | 17D | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7259 | 1-(2-chlorophenyl)-3-{2-[(4,5-dichloro-1H-imidazol-1-yl)methyl]-1,3-thiazol-4-yl}urea | NA | NA | Yellow fever virus | 17D | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7260 | 2-chloro-6-(4-chlorophenoxy)-4-{4-methyl-5-[(1E)-1-(2-phenylhydrazin-1-ylidene)ethyl]-1,3-thiazol-2-yl}pyridine | NA | NA | Yellow fever virus | 17D | | Plaque assay | Decrease (50 %) | NA | 19781577 |
DrugRepV_7263 | PI-88 | NA | Hepatocellular carcinoma | Liver cancer | Melanoma | Multiple myeloma | Japanese encephalitis virus | Nakayama | | Flow cytometry | Decrease (66 %) | Investigational | 16309754 |
DrugRepV_7265 | PPS | NA | NA | Japanese encephalitis virus | Nakayama | | Flow cytometry | Decrease (70 %) | NA | 16309754 |
DrugRepV_7266 | PI-88 | NA | Hepatocellular carcinoma | Liver cancer | Melanoma | Multiple myeloma | West Nile virus | NY-99 | | Flow cytometry | Decrease (66 %) | Investigational | 16309754 |
DrugRepV_7267 | Cdt yellow | NA | NA | Yellow fever virus | 17D | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_7268 | Cdt white | NA | NA | Yellow fever virus | 17D | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_7269 | Crotoxin | NA | NA | Yellow fever virus | 17D | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_7270 | Crotapotin | NA | NA | Yellow fever virus | 17D | | NA | Decrease (43 %) | NA | 21723310 |
DrugRepV_7271 | Crotamin | NA | NA | Yellow fever virus | 17D | | NA | Decrease (20 %) | NA | 21723310 |
DrugRepV_7272 | Convulxin | NA | NA | Yellow fever virus | 17D | | NA | Decrease (22 %) | NA | 21723310 |
DrugRepV_7273 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_7274 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | NA | Decrease (50 %) | NA | 21723310 |
DrugRepV_7275 | Cdt yellow | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7276 | Cdt white | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7277 | Crotoxin | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7278 | Crotapotin | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7279 | Crotamin | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (14.34 %) | NA | 21723310 |
DrugRepV_7280 | Convulxin | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (25.5 %) | NA | 21723310 |
DrugRepV_7281 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7282 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | Virucidal assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7283 | Cdt yellow | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7284 | Cdt white | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7285 | Crotoxin | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7286 | Crotapotin | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7287 | Crotamin | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7288 | Convulxin | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7289 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7290 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | Adsorption assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7291 | Cdt yellow | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7292 | Cdt white | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7293 | Crotoxin | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7294 | Crotapotin | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7295 | Crotamin | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (32 %) | NA | 21723310 |
DrugRepV_7296 | Convulxin | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (-70 %) | NA | 21723310 |
DrugRepV_7297 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (50 %) | NA | 21723310 |
DrugRepV_7298 | PLA2-IC | NA | NA | Yellow fever virus | 17D | | Internalization assay | Decrease (46 %) | NA | 21723310 |
DrugRepV_7299 | (3E)-N-tert-butyl-2-oxo-4-phenylbut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (20 %) | NA | 21641807 |
DrugRepV_7300 | (3E)-N-tert-butyl-3-methyl-2-oxo-4-phenylbut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (0 %) | NA | 21641807 |
DrugRepV_7301 | (3E)-N-tert-butyl-2-oxo-4-(thiophen-2-yl)but-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (20.3 %) | NA | 21641807 |
DrugRepV_7302 | (3E)-N-tert-butyl-4-(4-methoxyphenyl)-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (27.3 %) | NA | 21641807 |
DrugRepV_7303 | (3E)-N-tert-butyl-4-(3,4-dimethoxyphenyl)-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (31 %) | NA | 21641807 |
DrugRepV_7304 | (3E)-N-tert-butyl-4-(4-hydroxyphenyl)-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (31.4 %) | NA | 21641807 |
DrugRepV_7305 | (3E)-4-(4-aminophenyl)-N-tert-butyl-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (39.5 %) | NA | 21641807 |
DrugRepV_7306 | (3E)-N-tert-butyl-4-(4-chlorophenyl)-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (6.3 %) | NA | 21641807 |
DrugRepV_7307 | (3E)-N-tert-butyl-4-(1H-indol-3-yl)-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (40.6 %) | NA | 21641807 |
DrugRepV_7308 | (3E)-N-tert-butyl-4-[4-(dimethylamino)phenyl]-2-oxobut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (33.9 %) | NA | 21641807 |
DrugRepV_7309 | (3E)-N-cyclopropyl-2-oxo-4-phenylbut-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (20 %) | NA | 21641807 |
DrugRepV_7310 | 2-[(3E)-2-oxo-4-phenylbut-3-enamido]ethyl acetate | NA | NA | West Nile virus | NA | | Protease assay | Decrease (29.8 %) | NA | 21641807 |
DrugRepV_7311 | (3E)-2-oxo-4-phenyl-N-(1-phenylethyl)but-3-enamide | NA | NA | West Nile virus | NA | | Protease assay | Decrease (12.2 %) | NA | 21641807 |
DrugRepV_7312 | methyl 3-hydroxy-2-[(3E)-2-oxo-4-phenylbut-3-enamido]propanoate | NA | NA | West Nile virus | NA | | Protease assay | Decrease (27.5 %) | NA | 21641807 |
DrugRepV_7313 | CW-33A | NA | NA | Japanese encephalitis virus | T1P1 | | Virus yield reduction assay | Decrease (50 %) | NA | 30413749 |
DrugRepV_7314 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Virus yield reduction assay | Decrease (50 %) | NA | 30413749 |
DrugRepV_7315 | CW-33A | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 30413749 |
DrugRepV_7316 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 30413749 |
DrugRepV_7319 | MJ-47 | NA | NA | Japanese encephalitis virus | JEVSRIP | | Flow cytometry | Decrease (50 %) | NA | 28394283 |
DrugRepV_7320 | N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-[(4-nitro-1H-pyrazol-1-yl)methyl]benzamide | NA | NA | Japanese encephalitis virus | NS3 helicase | | Flow cytometry | Decrease (79 %) | NA | 27679979 |
DrugRepV_7321 | N-[6-({[(thiophen-2-yl)formamido]methanethioyl}amino)-1,3-benzothiazol-2-yl]butanamide | NA | NA | Japanese encephalitis virus | NS3 helicase | | Flow cytometry | Decrease (73 %) | NA | 27679979 |
DrugRepV_7322 | N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-[(4-nitro-1H-pyrazol-1-yl)methyl]benzamide | NA | NA | Japanese encephalitis virus | P3 | | Western blot | Decrease (70.1 %) | NA | 27679979 |
DrugRepV_7323 | N-[6-({[(thiophen-2-yl)formamido]methanethioyl}amino)-1,3-benzothiazol-2-yl]butanamide | NA | NA | Japanese encephalitis virus | P3 | | Western blot | Decrease (94.8 %) | NA | 27679979 |
DrugRepV_7324 | N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-[(4-nitro-1H-pyrazol-1-yl)methyl]benzamide | NA | NA | Japanese encephalitis virus | P3 | | Immunoflourescence assay | Decrease (86.71 %) | NA | 27679979 |
DrugRepV_7325 | N-[6-({[(thiophen-2-yl)formamido]methanethioyl}amino)-1,3-benzothiazol-2-yl]butanamide | NA | NA | Japanese encephalitis virus | P3 | | Immunoflourescence assay | Decrease (89.3 %) | NA | 27679979 |
DrugRepV_7326 | N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-[(4-nitro-1H-pyrazol-1-yl)methyl]benzamide | NA | NA | Japanese encephalitis virus | P3 | | Plaque assay | Decrease (2 log pfu/ml) | NA | 27679979 |
DrugRepV_7327 | N-[6-({[(thiophen-2-yl)formamido]methanethioyl}amino)-1,3-benzothiazol-2-yl]butanamide | NA | NA | Japanese encephalitis virus | P3 | | Plaque assay | Decrease (2 log pfu/ml) | NA | 27679979 |
DrugRepV_7328 | N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-[(4-nitro-1H-pyrazol-1-yl)methyl]benzamide | NA | NA | Japanese encephalitis virus | P3 | | Cell viability assay | Decrease (50 %) | NA | 27679979 |
DrugRepV_7329 | N-[6-({[(thiophen-2-yl)formamido]methanethioyl}amino)-1,3-benzothiazol-2-yl]butanamide | NA | NA | Japanese encephalitis virus | P3 | | Cell viability assay | Decrease (50 %) | NA | 27679979 |
DrugRepV_7330 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Cytopathic effect (CPE) assay | Decrease | NA | 27563890 |
DrugRepV_7331 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Cytopathic effect (CPE) assay | Decrease | NA | 27563890 |
DrugRepV_7332 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (5 times pfu/ml) | NA | 27563890 |
DrugRepV_7333 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (3 times pfu/ml) | NA | 27563890 |
DrugRepV_7334 | CW-33 | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 27563890 |
DrugRepV_7335 | FGIN-1-27 | NA | NA | Japanese encephalitis virus | P3 | | Plaque assay | Decrease (2 log %) | NA | 24348901 |
DrugRepV_7338 | FGIN-1-27 | NA | NA | Japanese encephalitis virus | P3 | | Immunoflourescence assay | Decrease (80 %) | NA | 24348901 |
DrugRepV_7341 | FGIN-1-27 | NA | NA | Japanese encephalitis virus | P3 | | Luminescence assay | Decrease (50 %) | NA | 24348901 |
DrugRepV_7348 | Indigo | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 22911608 |
DrugRepV_7349 | Indirubin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | Investigational | 22911608 |
DrugRepV_7350 | Indirubin | NA | NA | Japanese encephalitis virus | Beijing-1 | | Survival assay | Increase | Investigational | 22911608 |
DrugRepV_7351 | NG-monomethyl-L-arginine | NA | Obesity | Type 2 Diabetes | Ocular Physiology | Regional Blood Flow | Japanese encephalitis virus | 78668A | | Survival assay | Decrease | Approved, Investigational | 10762444 |
DrugRepV_7352 | N-nitro-L-arginine methyl ester | NA | NA | Japanese encephalitis virus | RP-9 | | Survival assay | Decrease | NA | 9188590 |
DrugRepV_7353 | S-nitroso-N-acetylpenicillamine | NA | NA | Japanese encephalitis virus | NT109 | | Plaque assay | Decrease (3 log pfu/ml) | NA | 9188590 |
DrugRepV_7354 | Glycine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (16.37 %) | NA | 14011545 |
DrugRepV_7355 | DL-Phenylalanine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | No significant effect (3.63 %) | NA | 14011545 |
DrugRepV_7356 | L-Leucine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | No significant effect (3.63 %) | NA | 14011545 |
DrugRepV_7357 | DL-Aspartic acid -Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Decrease (23.63 %) | NA | 14011545 |
DrugRepV_7358 | DL-Asparagine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Decrease (36.36 %) | NA | 14011545 |
DrugRepV_7359 | DL-Alanine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (9 %) | NA | 14011545 |
DrugRepV_7360 | L-Cysteine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Decrease (18.18 %) | NA | 14011545 |
DrugRepV_7361 | DL-Lysine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (9 %) | NA | 14011545 |
DrugRepV_7362 | L-Tyrosine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | No significant effect (10 %) | NA | 14011545 |
DrugRepV_7363 | DL-Methionine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (20 %) | NA | 14011545 |
DrugRepV_7364 | 2-Picolinic acid-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (0.45 %) | NA | 14011545 |
DrugRepV_7365 | Guanidine-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (9.5 %) | NA | 14011545 |
DrugRepV_7366 | Diethyl Dithiocarbamic Acid-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (27.72 %) | NA | 14011545 |
DrugRepV_7367 | Diphenylthiocarbazone-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (12.14 %) | NA | 14011545 |
DrugRepV_7368 | 8-Hydroxyquinoline-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | No significant effect (8.6 %) | NA | 14011545 |
DrugRepV_7369 | 3,4-Dimercaptotoluene-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Increase (10 %) | NA | 14011545 |
DrugRepV_7370 | 1,10-Phenanthroline-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | No significant effect (5 %) | NA | 14011545 |
DrugRepV_7371 | 1,10-Phenanthroline-3,4-dimercaptotoluene-Zn | NA | NA | Japanese encephalitis virus | Nakayama | | Paralysis | Decrease (35 %) | NA | 14011545 |
DrugRepV_7372 | Luteolin | NA | NA | Japanese encephalitis virus | SX09S01 | | Plaque assay | Decrease (50 %) | NA | 27126774 |
DrugRepV_7373 | Luteolin | NA | NA | Japanese encephalitis virus | SX09S01 | | Plaque assay | Decrease (2 log Log PFU/ml) | NA | 27126774 |
DrugRepV_7374 | Luteolin | NA | NA | Japanese encephalitis virus | SX09S01 | | Western blot | Decrease | NA | 27126774 |
DrugRepV_7375 | Chrysophanol | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 24395532 |
DrugRepV_7376 | Aloe-emodin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 24395532 |
DrugRepV_7377 | Aloe-emodin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 18701259 |
DrugRepV_7378 | Aloe-emodin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 18701259 |
DrugRepV_7379 | Shikonin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 18701259 |
DrugRepV_7380 | Shikonin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | NA | 18701259 |
DrugRepV_7381 | Arecoline | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | Experimental | 18701259 |
DrugRepV_7382 | Arecoline | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | Experimental | 18701259 |
DrugRepV_7383 | Hesperetin | NA | NA | Japanese encephalitis virus | T1P1 | | Plaque assay | Decrease (50 %) | Experimental | 18701259 |
DrugRepV_7384 | Dehydroepiandrosterone | NA | Schizophrenia | Japanese encephalitis virus | NT113 | | Plaque assay | Decrease | Approved | 16099910 |
DrugRepV_7385 | Dehydroepiandrosterone | NA | Schizophrenia | Japanese encephalitis virus | NT113 | | Slot Blot analysis | Decrease | Approved | 16099910 |
DrugRepV_7386 | Dehydroepiandrosterone | NA | Schizophrenia | Japanese encephalitis virus | NT113 | | Western blot | Decrease | Approved | 16099910 |
DrugRepV_7387 | SCH16-Ribavirin | NA | NA | Japanese encephalitis virus | P20778 | | Cytopathic effect (CPE) assay | Decrease | NA | 22738253 |
DrugRepV_7388 | SCH16-Mycophenolic acid | NA | NA | Japanese encephalitis virus | P20778 | | Cytopathic effect (CPE) assay | Decrease | NA | 22738253 |
DrugRepV_7389 | Delphinidin Chloride | NA | NA | West Nile virus | NY-99 | | Plaque assay | Decrease (O.6 Log) | NA | 28744282 |
DrugRepV_7390 | Cyanidin Chloride | NA | NA | West Nile virus | NY-99 | | Plaque assay | No significant effect (No significant effect Log) | NA | 28744282 |
DrugRepV_7392 | Epicatechin | NA | Pre-diabetes | West Nile virus | NY-99 | | Plaque assay | No significant effect (No significant effect Log) | Investigational | 28744282 |
DrugRepV_7393 | Epigallocatechin | NA | NA | West Nile virus | NY-99 | | Plaque assay | Decrease (0.5 Log) | Experimental | 28744282 |
DrugRepV_7395 | Delphinidin Chloride | NA | NA | West Nile virus | NY-99 | | RT-PCR | Decrease (0.7 Copies/cell) | NA | 28744282 |
DrugRepV_7397 | Nordihydroguaiaretic Acid | NA | Actinic keratoses | West Nile virus | NY-99 | | Plaque assay | Decrease (50 %) | Approved, Investigational | 28507114 |
DrugRepV_7398 | Nordihydroguaiaretic Acid | NA | Actinic keratoses | West Nile virus | NY-99 | | Plaque assay | Decrease (50 %) | Approved, Investigational | 28507114 |
DrugRepV_7400 | PF-429242 | NA | NA | West Nile virus | NY-99 | | Plaque assay | Decrease (0.4 Log) | NA | 28507114 |
DrugRepV_7401 | Fatostatin | NA | NA | West Nile virus | NY-99 | | Plaque assay | Decrease (0.7 Log) | NA | 28507114 |
DrugRepV_7402 | Zileuton | NA | Asthma | West Nile virus | NY-99 | | Plaque assay | No significant change (No significant change Log) | Approved / Withdrawn | 28507114 |
DrugRepV_7403 | BCX4430 | NA | Ebola virus | West Nile virus | Eg101 | | Plaque assay | Decrease (50 %) | Investigational | 28336346 |
DrugRepV_7404 | BCX4430 Hydrochloride | NA | Ebola virus | West Nile virus | Eg101 | | Plaque assay | Decrease (50 %) | Investigational | 28336346 |
DrugRepV_7405 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7406 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]thymine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7407 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorouracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7408 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]cytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7409 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorocytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7410 | L-Neplanocin A | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7411 | (1S,2R,3S)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl] hypoxanthine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7412 | (1S,2R,3S)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]guanine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7413 | Cyclopentenyl nucleosides | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7414 | (1R,2S,3R)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl] hypoxanthine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7415 | (1R,2S,3R)-9-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]guanine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7416 | (1S,2R,3S)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]uracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7417 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]thymine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7418 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorouracil | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7419 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]cytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7420 | (1R,2S,3R)-1-[2,3-Dihydroxy-4-hydroxymethyl-4-cyclopenten-1-yl]-5-fluorocytosine | NA | NA | West Nile virus | New York isolate | | CPE inhibition assay | Decrease (50 %) | NA | 11689085 |
DrugRepV_7421 | N-nonyl-deoxynojirimycin | NA | NA | West Nile virus | NA | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_7422 | N-pentyl-(1-hydroxycyclohexyl)-DNJ | NA | NA | West Nile virus | NA | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_7423 | N-Propylcyclohexyl-DNJ | NA | NA | West Nile virus | NA | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_7424 | N-Butylcyclohexyl-DNJ | NA | NA | West Nile virus | NA | | Yield reduction assay | Decrease (50 %) | NA | 17354651 |
DrugRepV_7426 | 6-Azauridine | NA | Cancer | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7427 | 6-Azauridine | NA | Cancer | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7428 | 6-Azauridine triacetate | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7429 | 6-Azauridine triacetate | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7430 | Pyrazofurin | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7431 | Pyrazofurin | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7432 | 2-Thio-6-azauridine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7433 | 2-Thio-6-azauridine | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7434 | 6-Azauridine | NA | Cancer | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7435 | 6-Azauridine | NA | Cancer | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7436 | 6-Azauridine triacetate | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7437 | 6-Azauridine triacetate | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7438 | Pyrazofurin | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7439 | Pyrazofurin | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7440 | 2-Thio-6-azauridine | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7441 | 2-Thio-6-azauridine | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7442 | 3-Deazaguanosine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7445 | Ribamidine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7446 | Ribamidine | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7449 | Selenazofurin | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7450 | Selenazofurin | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7452 | beta-Methylene TAD | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7453 | beta-Methylene TAD | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7454 | 3-Deazaguanosine | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7457 | Ribamidine | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7458 | Ribamidine | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7461 | Selenazofurin | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7462 | Selenazofurin | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7464 | beta-Methylene TAD | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7465 | beta-Methylene TAD | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7466 | 3-Deazauridine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7467 | 3-Deazauridine | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7468 | Cyclopentenylcytosine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7469 | Cyclopentenylcytosine | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7470 | 3-Deazauridine | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7471 | 3-Deazauridine | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7472 | Cyclopentenylcytosine | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7473 | Cyclopentenylcytosine | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7480 | 5-fluorouridine | NA | Cancer | West Nile virus | New York | | Visual assay | Decrease (50 %) | Experimental | 12076755 |
DrugRepV_7481 | 5-fluorouridine | NA | Cancer | West Nile virus | New York | | NR assay | Decrease (50 %) | Experimental | 12076755 |
DrugRepV_7482 | (S )-DHPA | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7483 | (S )-DHPA | NA | NA | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7484 | 3-Deazaneplanocin A | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7485 | (S )-DHPA | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7486 | (S )-DHPA | NA | NA | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7487 | 3-Deazaneplanocin A | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7488 | 6-Bromotoyocamycin | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7489 | Formycin B | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | Experimental | 12076755 |
DrugRepV_7490 | 6-Bromotoyocamycin | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7491 | Formycin B | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | Experimental | 12076755 |
DrugRepV_7492 | 2-Thiouracil | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7494 | Cyclopentyluracil | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7495 | Dihydro-5-azacytidine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7496 | Uridine 2,3-dialdehyde | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7497 | 2-Thiouracil | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7499 | Cyclopentyluracil | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7500 | Dihydro-5-azacytidine | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7501 | Uridine 2,3-dialdehyde | NA | NA | West Nile virus | New York | | NR assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7502 | 6-Azauridine | NA | Cancer | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7503 | 6-Azauridine triacetate | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7504 | Pyrazofurin | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7505 | Selenazofurin | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7508 | Cyclopentenylcytosine | NA | NA | West Nile virus | New York | | Visual assay | Decrease (50 %) | NA | 12076755 |
DrugRepV_7509 | 6-Azauridine | NA | Cancer | West Nile virus | New York | | Virus yield reduction assay | Decrease (90 %) | NA | 12076755 |
DrugRepV_7510 | Pyrazofurin | NA | NA | West Nile virus | New York | | Virus yield reduction assay | Decrease (90 %) | NA | 12076755 |
DrugRepV_7513 | Cyclopentenylcytosine | NA | NA | West Nile virus | New York | | Virus yield reduction assay | Decrease (90 %) | NA | 12076755 |
DrugRepV_7514 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Polio virus | NA | | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_7515 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | West Nile virus | NA | | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_7516 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Yellow fever virus | NA | | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_7517 | Aloe-emodin | NA | NA | Enterovirus | EV71 | | Plaque assay | Decrease (50 %) | NA | 18701259 |
DrugRepV_7518 | Aloe-emodin | NA | NA | Enterovirus | EV71 | | Plaque assay | Decrease (50 %) | NA | 18701259 |
DrugRepV_7520 | beta-D-cyclopentenyl cytosine | NA | NA | Vaccinia virus | Copenhagen | | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_7521 | beta-D-cyclopentenyl-5-iodocytidine | NA | NA | Vaccinia virus | Copenhagen | | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_7522 | beta-D-Cyclopentenyl-5-chlorocytidine | NA | NA | Vaccinia virus | Copenhagen | | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_7523 | beta-D-cyclopentenyl-5-bromocytidine | NA | NA | Vaccinia virus | Copenhagen | | NA | Decrease (50 %) | NA | 14604375 |
DrugRepV_7524 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Vaccinia virus | NA | | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_7575 | Merimepodib | NA | NA | SARS Coronavirus-2 | SARS-CoV-2 USA-WA1/2020 | NA | RT-PCR | Decrease (50 %) | Investigational | 32438446 |
DrugRepV_7576 | Merimepodib | NA | NA | SARS Coronavirus-2 | SARS-CoV-2 USA-WA1/2020 | NA | RT-PCR | Decrease (90 %) | Investigational | 32438446 |
DrugRepV_7664 | Cetilistat | NA | Obesity | SARS Coronavirus-2 | | NA | Plaque reduction assay | Decrease (50 %) | Investigational | 32473310 |
DrugRepV_7668 | Cetilistat | NA | Obesity | SARS Coronavirus-2 | | NA | Viral load reduction assay | Decrease (90 %) | Investigational | 32473310 |
DrugRepV_7673 | ROC-325 | NA | NA | SARS Coronavirus-2 | | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32511355 |
DrugRepV_7690 | S1RA | NA | NA | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | NA | 32577649 |
DrugRepV_7693 | Z-FA-FMK | NA | NA | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | NA | 32577649 |
DrugRepV_7694 | Lactoferrin | NA | NA | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | NA | 32577649 |
DrugRepV_7695 | Nafamostat | NA | Blood vessel coagulation | Hemorrhagic lesions | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | Investigational | 32532094 |
DrugRepV_7696 | Immunoglobulin F(ab’)2 | NA | NA | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | NA | 32659292 |
DrugRepV_7697 | Unfractionated Heparin | NA | Prophylaxis and Venous thrombosis | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | Approved, Investigational | 32577638 |
DrugRepV_7698 | UFH-de6S | NA | NA | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | NA | 32577638 |
DrugRepV_7700 | Enoxaparin-de6S | NA | NA | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | NA | 32577638 |
DrugRepV_7701 | Pegasys | NA | Hepatitis C Virus | SARS Coronavirus-2 | | NA | Plaque reduction assay | Decrease (50 %) | Approved, Investigational | 32532085 |
DrugRepV_7705 | Immukin | NA | Chronic granulomatous disease and Osteopetrosis | SARS Coronavirus-2 | | NA | Plaque reduction assay | Decrease (50 %) | Approved, Investigational | 32532085 |
DrugRepV_7706 | 25-Hydroxycholesterol | NA | NA | SARS Coronavirus-2 | NA | NA | Plaque reduction assay | Decrease (50 %) | Experimental | 32532085 |
DrugRepV_7707 | AM580 | NA | NA | SARS Coronavirus-2 | | NA | Plaque reduction assay | Decrease (50 %) | NA | 32532085 |
DrugRepV_7710 | AMG-2674 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7713 | DS-6930 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7714 | Elopiprazole | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7715 | Hanfangchin A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7716 | KW 8232 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7717 | N-tert-Butylisoquine | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7718 | R 82913 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Experimental | 32707573 |
DrugRepV_7719 | SB-616234A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7720 | SDZ-62-434 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7721 | SL-11128 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7722 | YH-1238 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7724 | AMG-2674 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7727 | Elopiprazole | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7728 | Hanfangchin A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7729 | MLN-3897 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7730 | KW 8232 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7731 | N-tert-Butylisoquine | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7732 | SB-616234A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7733 | SDZ-62-434 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7734 | SL-11128 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7736 | 8-(2-Chlorostyryl)caffeine | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7737 | AMG-2674 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7739 | Elopiprazole | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7740 | Hanfangchin A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7741 | KW 8232 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7742 | MLN-3897 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7743 | N-tert-Butylisoquine | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7744 | SB-616234A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7745 | SDZ-62-434 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7746 | YH-1238 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7748 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Investigational | 32707573 |
DrugRepV_7749 | VBY-825 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7750 | ONO 5334 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7751 | Z LVG CHN2 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7752 | MDL 28170 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7753 | SL-11128 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7755 | DS-6930 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7756 | R 82913 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Experimental | 32707573 |
DrugRepV_7757 | Hanfangchin A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7758 | SB-616234A | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7759 | MLN-3897 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7760 | VBY-825 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7761 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Investigational | 32707573 |
DrugRepV_7762 | VBY-825 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7763 | ONO 5334 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7764 | Z LVG CHN2 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7765 | MDL 28170 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7766 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Investigational | 32707573 |
DrugRepV_7767 | VBY-825 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7768 | ONO 5334 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7769 | Z LVG CHN2 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7770 | MDL 28170 | NA | NA | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | NA | 32707573 |
DrugRepV_7773 | Galidesivir | NA | Ebolavirus | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Investigational | 32687696 |
DrugRepV_7775 | Camostat mesylate | NA | Pancreatitis | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Experimental | 32687696 |
DrugRepV_7776 | Nafamostat Mesylate | NA | Blood vessel coagulation | Hemorrhagic lesions | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Investigational | 32687696 |
DrugRepV_7778 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Investigational | 32687696 |
DrugRepV_7788 | SSAA09E3 | NA | NA | Severe acute respiratory syndrome coronavirus | Toronto-2 | NA | Dose-dependence fluorescence inhibition assay | Decrease (50 %) | NA | 23678171 |
DrugRepV_7789 | SSAA09E1 | NA | NA | Severe acute respiratory syndrome coronavirus | Toronto-2 | NA | Dose-dependence fluorescence inhibition assay | Decrease (50 %) | NA | 23678171 |
DrugRepV_7790 | SSAA09E2 | NA | NA | Severe acute respiratory syndrome coronavirus | Toronto-2 | NA | Dose-dependence fluorescence inhibition assay | Decrease (50 %) | NA | 23678171 |
DrugRepV_7791 | Ferruginol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Cell based assay | Decrease (50 %) | NA | 17663539 |
DrugRepV_7792 | Dehydroabieta-7-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7793 | Cryptojaponol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7794 | 8beta-hydroxyabieta-9(11),13- dien-12-one | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7795 | 7beta-hydroxydeoxycryptojaponol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7796 | 6,7-dehydroroyleanone | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7797 | 3beta,12-diacetoxyabieta-6,8,11,13- tetraene | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7798 | Pinusolidic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7799 | Forskolin | NA | Smooth muscle relaxant | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Experimental, Investigational | 17663539 |
DrugRepV_7800 | Cedrane-3beta,12-diol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7801 | alpha-cadinol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7802 | Betulinic acid | NA | Dysplastic Nevus Syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Investigational | 17663539 |
DrugRepV_7803 | Betulonic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7804 | Hinokinin | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7805 | Savinin | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7806 | Honokiol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7807 | Magnolol | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17663539 |
DrugRepV_7808 | Curcumin | NA | Depressive disorder | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Approved | 17663539 |
DrugRepV_7810 | Valinomycin | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Experimental | 17663539 |
DrugRepV_7813 | 2-aminobenzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | Experimental | 16638531 |
DrugRepV_7814 | 2-(5-bromopyridin-3-yl)-1-[5-(4-chlorophenyl)furan-2-yl]-2-fluoroethanone | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 18295820 |
DrugRepV_7815 | ML188 | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Luminescent Cell Viability Assay | Decrease (50 %) | NA | 23231439 |
DrugRepV_7816 | ML300 | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7817 | 2-(benzotriazol-1-yl)-N-(4-phenylphenyl)-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7818 | 5-Chloro-pyridin-3-yl Furan-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7819 | 5-Chloropyridin-3-yl Benzofuran-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7820 | 5-Bromo-pyridin-3-yl Furan-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7821 | 5-Chloro-pyridin-3-yl-1H-indole-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7822 | 5-Chloropyridin-3-yl-benzo-(b)-thiophene-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7823 | 5-Chloropyridin-3-yl-thiazole-4-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7824 | 5-Chloropyridin-3-yl-3-methoxybenzoate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7825 | 5-Chloropyridin-3-yl-5-(4-chlorophenyl)furan-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric assay | Decrease (50 %) | NA | 17381079 |
DrugRepV_7826 | N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]propanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7827 | N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]-2-methylpropanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7828 | N-{4-[(1H-Benzotriazol-1-ylacetyl)(3-thienylmethyl)amino]phenyl}-2,2-dimethylpropanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7829 | N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]-3-methoxypropanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7830 | N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]cyclobutanecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7831 | N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]cyclohexanecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7832 | N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]benzamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7833 | 2-methylpropyl N-[4-[[2-(benzotriazol-1-yl)acetyl]-(thiophen-3-ylmethyl)amino]phenyl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7834 | 2-(benzotriazol-1-yl)-N-[4-(methylamino)phenyl]-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7835 | 2-(benzotriazol-1-yl)-N-[4-(benzylamino)phenyl]-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7836 | 2-(benzotriazol-1-yl)-N-(4-pyridin-3-ylphenyl)-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7837 | 2-(benzotriazol-1-yl)-N-[4-(2-methoxypyridin-3-yl)phenyl]-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7838 | 2-(benzotriazol-1-yl)-N-(4-pyridin-4-ylphenyl)-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7839 | 2-(benzotriazol-1-yl)-N-[4-(2-methoxypyrimidin-5-yl)phenyl]-N-(thiophen-3-ylmethyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 24080461 |
DrugRepV_7840 | benzyl N-[(2S)-1-[[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxo-1-[(4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl)amino]pentan-2-yl]amino]-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7841 | (4S)-4-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-3-phenylmethoxybutanoyl]amino]-4-methylpentanoyl]amino]-N,N-dimethyl-6-(5-nitro-1,4-dioxo-3H-phthalazin-2-yl)-5-oxohexanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7842 | methyl (E,4S)-4-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7843 | ethyl 3-[(3-amino-3-oxopropyl)-[[(2R,5S)-2-benzyl-7-methyl-4-oxo-5-(phenylmethoxycarbonylamino)octanoyl]amino]carbamoyl]oxirane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7844 | (2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-N-[(2S)-3-cyclohexyl-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methylbutanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7845 | N-[(Benzyloxy)carbonyl]valyl-N-[1-oxo-3-(2-oxo-3-pyrrolidinyl)-1-(1,3-thiazol-2-yl)-2-propanyl]leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7846 | N-[(Benzyloxy)carbonyl]-L-valyl-N-{(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-D-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7847 | N-{[3-(Dimethylamino)phenoxy]acetyl}-L-valyl-N-{(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7848 | 2-[2,3-Dichloro-4-(2-methylenebutanoyl)phenoxy]-N-(2-methyl-2-propanyl)acetamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7849 | Cinanserin | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7850 | 5-Chloro-3-pyridinyl 1H-indole-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7851 | 1-(2-Naphthylmethyl)-2,3-dioxo-5-indolinecarboxamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7852 | 1-[(1H-Indol-5-ylcarbonyl)oxy]-1H-benzotriazole | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7853 | 4-(4-Chlorophenyl)-2-[(4-nitrobenzyl)sulfanyl]-6-oxo-1,6-dihydro-5-pyrimidinecarbonitrile | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7854 | 4-{(Z)-[1-(4-Fluorophenyl)-5-oxo-3-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}benzoic acid | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7855 | 3-Benzyl-1-[(6,7-dimethyl-2-oxo-1,2-dihydro-3-quinolinyl)methyl]-1-[2-(2-methylphenyl)ethyl]urea | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7856 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N2-(3-methylbutanoyl)-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7857 | tert-butyl N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7858 | benzyl N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7859 | benzyl N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-1-oxohexan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7860 | benzyl N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7861 | Benzyl [(2S,3R)-1-({(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}amino)-3-methyl-1-oxo-2-pentanyl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7862 | benzyl N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7863 | benzyl N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7864 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-4-methyl-2-[(2-phenylacetyl)amino]pentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7865 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-2-[[2-(4-methoxyphenyl)acetyl]amino]-4-methylpentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7866 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-2-[3-(4-methoxyphenyl)propanoylamino]-4-methylpentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7867 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N2-[3-(3-pyridinyl)propanoyl]-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7868 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N~2~-[(2E)-3-phenyl-2-propenoyl]-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7869 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N~2~-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7870 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N~2~-[(2E)-3-(3,4-dimethoxyphenyl)-2-propenoyl]-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7871 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-4-methyl-2-[(2-phenoxyacetyl)amino]pentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7872 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N~2~-[(4-methoxyphenoxy)acetyl]-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7873 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-2-[[2-(4-hydroxyphenoxy)acetyl]amino]-4-methylpentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7874 | N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-N~2~-{[3-(dimethylamino)phenoxy]acetyl}-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7875 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-2-[[2-(4-methoxyanilino)acetyl]amino]-4-methylpentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7876 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-2-[[2-(3-methoxyanilino)acetyl]amino]-4-methylpentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7877 | (2S)-N-[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]-2-[[2-(2-methoxyanilino)acetyl]amino]-4-methylpentanamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease (50 %) | NA | 23747811 |
DrugRepV_7878 | benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]-1-(5-phenyl-1,3-thiazol-2-yl)propan-2-yl]amino]pentan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7879 | N~2~-[(Benzyloxy)carbonyl]-N-{(2S)-1-[5-(4-methylphenyl)-1,3-thiazol-2-yl]-1-oxo-3-[(3S)-2-oxo-3-pyrrolidinyl]-2-propanyl}-L-leucinamide | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7880 | benzyl N-[(2S)-1-[[(2S)-1-[5-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7881 | benzyl N-[(2S)-1-[[(2S)-1-[5-(2-methoxyphenyl)-1,3-thiazol-2-yl]-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | Fluorometric protease inhibitory assay | Decrease | NA | 23747811 |
DrugRepV_7882 | 5-chloropyridin-3-yl 5-(4-chlorophenyl)oxolane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7883 | 5-chloropyridin-3-yl 5-(4-nitrophenyl)oxolane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7884 | 5-chloropyridin-3-yl 5-(4-chloro-2-nitrophenyl)oxolane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7885 | 5-chloropyridin-3-yl 5-(2-nitrophenyl)oxolane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7886 | 5-chloropyridin-3-yl 5-(3-nitrophenyl)oxolane-2-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7887 | (5-chloropyridin-3-yl) pyridine-4-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7888 | (5-chloropyridin-3-yl) pyridine-3-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7889 | (5-chloropyridin-3-yl) 4-chlorobenzoate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7890 | (5-chloropyridin-3-yl) 2-nitrobenzoate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7891 | (5-chloropyridin-3-yl) 3-nitrobenzoate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7892 | 5-Chloro-3-pyridinyl 1-naphthoate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7893 | (5-chloropyridin-3-yl) 2-oxochromene-3-carboxylate | NA | NA | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | NA | 17931870 |
DrugRepV_7895 | Rotenone | NA | NA | Lassa virus | NA | NA | GLuc assay | Decrease (50 %) | Vet approved | 31786250 |
DrugRepV_7899 | Lycorine | NA | NA | Japanese encephalitis virus | NA | | NA | Decrease (50 %) | NA | 31871089 |
DrugRepV_7900 | Cephalotaxlen | NA | NA | Japanese encephalitis virus | NA | | NA | Decrease (50 %) | NA | 31871089 |
DrugRepV_7901 | Schisandrin B | NA | NA | Japanese encephalitis virus | NA | | NA | Decrease (50 %) | NA | 31871089 |
DrugRepV_7902 | Procyanidin | NA | NA | Japanese encephalitis virus | NA | | NA | Decrease (50 %) | NA | 31871089 |
DrugRepV_7903 | Emodin | NA | Polycystic Kidney | Japanese encephalitis virus | NA | | NA | Decrease (50 %) | Investigational | 31871089 |
DrugRepV_7904 | Schisandrin B | NA | NA | Japanese encephalitis virus | NA | | NA | Decrease (50 %) | NA | 31871089 |
DrugRepV_7905 | RK-33 | NA | NA | Dengue virus | New Guinea C | | Plaque assay | Decrease (50 %) | NA | 31936642 |
DrugRepV_7906 | RK-33 | NA | NA | Zika virus | Asian/Cook Islands/2014 | NA | Plaque assay | Decrease (50 %) | NA | 31936642 |
DrugRepV_7907 | RK-33 | NA | NA | West Nile virus | Kunjin | | Plaque assay | Decrease (50 %) | NA | 31936642 |
DrugRepV_7908 | Antimycin A | NA | NA | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7909 | Brequinar | NA | NA | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | Experimental | 31941776 |
DrugRepV_7910 | 6-Azauridine | NA | Cancer | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7911 | Azaribine | NA | Psoriasis | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7912 | Pyrazofurin | NA | NA | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7913 | AVN-944 | NA | Cancer | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | Investigational | 31941776 |
DrugRepV_7914 | Mycophenolate mofetil | NA | Organ rejection (immunosuppressants) | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | Approved, Investigational | 31941776 |
DrugRepV_7918 | Antimycin A | NA | NA | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7919 | Brequinar | NA | NA | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | Experimental | 31941776 |
DrugRepV_7920 | 6-Azauridine | NA | Cancer | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7921 | Azaribine | NA | Psoriasis | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7922 | Pyrazofurin | NA | NA | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7923 | AVN-944 | NA | Cancer | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | Investigational | 31941776 |
DrugRepV_7924 | Mycophenolate mofetil | NA | Organ rejection (immunosuppressants) | Influenza virus | B/Brisbane/60/08 | | MTT assay | Decrease (50 %) | Approved, Investigational | 31941776 |
DrugRepV_7926 | Antimycin A | NA | NA | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7927 | Brequinar | NA | NA | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | Experimental | 31941776 |
DrugRepV_7928 | 6-Azauridine | NA | Cancer | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7929 | Azaribine | NA | Psoriasis | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7930 | Pyrazofurin | NA | NA | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7931 | AVN-944 | NA | Cancer | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | Investigational | 31941776 |
DrugRepV_7932 | Mycophenolate mofetil | NA | Organ rejection (immunosuppressants) | Influenza virus | A/Puerto Rico/8/34 | | MTT assay | Decrease (50 %) | Approved, Investigational | 31941776 |
DrugRepV_7934 | Antimycin A | NA | NA | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7935 | Brequinar | NA | NA | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | Experimental | 31941776 |
DrugRepV_7936 | 6-Azauridine | NA | Cancer | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7937 | Azaribine | NA | Psoriasis | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7938 | Pyrazofurin | NA | NA | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | NA | 31941776 |
DrugRepV_7939 | AVN-944 | NA | Cancer | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | Investigational | 31941776 |
DrugRepV_7940 | Mycophenolate mofetil | NA | Organ rejection (immunosuppressants) | Influenza virus | A/New Caledonia/20/1999 | | MTT assay | Decrease (50 %) | Approved, Investigational | 31941776 |
DrugRepV_7942 | DHBNH | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7943 | 3-[(E)-{[(3,4-dihydroxyphenyl)formamido]imino}methyl]-[1,1'-biphenyl]-4-carboxylic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7944 | (3E)-3-{2-[4-(3,4-dihydroxyphenyl)-1,3-thiazol-2-yl]hydrazin-1-ylidene}-2,3-dihydro-1H-indol-2-one | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7945 | 4-[2-[(2-hydroxy-1H-indol-3-yl)diazenyl]-1,3-thiazol-4-yl]benzonitrile | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7946 | NSC727447 | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7947 | NSC732665 | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7948 | 2-(3,4-Dihydroxyphenyl)-1,5,6,7,8,9-hexahydro-4H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7949 | 2-(3,4-dihydroxybenzamido)-N-(pyridin-2-yl)-4H,5H,6H,7H,8H-cyclohepta[b]thiophene-3-carboxamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7950 | 5-(3,4-dihydroxyphenyl)-4-oxa-8-thia-6-azatricyclo[7.4.0.0²,?]trideca-1(9),2(7),5,10,12-pentaen-3-one | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7951 | (E)-3-(3,4-dihydroxyphenyl)-N-[(Z)-octadec-9-enyl]prop-2-enamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7952 | 4-Butoxy-N-(5-methyl-7-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7953 | 4-Butyl-N-(5-methyl-7-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7954 | 4-butyl-N-{5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7955 | 2-fluoro-N-{5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7956 | N-{5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-nitrobenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7957 | 4-amino-N-{5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7958 | 3,4-dimethoxy-N-{5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7959 | 3,4-dihydroxy-N-{5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7960 | 2-fluoro-N-{7-methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7961 | N-{7-methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-nitrobenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7962 | 4-amino-N-{7-methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7963 | 3,4-dimethoxy-N-{7-methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7964 | 3,4-dihydroxy-N-{7-methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7965 | 4-butyl-N-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7966 | N-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-2-fluorobenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7967 | N-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-4-nitrobenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7968 | 4-amino-N-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7969 | N-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-3,4-dimethoxybenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7970 | N-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-3,4-dihydroxybenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7971 | N-{5,7-diphenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-3,4-dihydroxybenzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7972 | N-[7-(3,4-dihydroxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7973 | N-benzoyl-N-[7-(3,4-dimethoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]benzamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7974 | N-(3,4-dihydroxyphenyl)-5-methyl-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7975 | N-(3,4-dihydroxyphenyl)-7-methyl-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 32151066 |
DrugRepV_7988 | 2-(6-{[1-carboxy-2-(2-phenyl-1H-indol-3-yl)ethyl]carbamoyl}-4-(2-{[1-carboxy-2-(2-phenyl-1H-indol-3-yl)ethyl]carbamoyl}ethyl)-4-nitrohexanamido)-3-(2-phenyl-1H-indol-3-yl)propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7989 | 2-[6-({1-carboxy-2-[2-(2-fluorophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(2-fluorophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(2-fluorophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7990 | 2-[6-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-nitrophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7991 | 3-[2-(4-bromophenyl)-1H-indol-3-yl]-2-[6-({2-[2-(4-bromophenyl)-1H-indol-3-yl]-1-carboxyethyl}carbamoyl)-4-[2-({2-[2-(4-bromophenyl)-1H-indol-3-yl]-1-carboxyethyl}carbamoyl)ethyl]-4-nitrohexanamido]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7992 | 2-{6-[(1-carboxy-2-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}-3-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7993 | 2-[6-({1-carboxy-2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-methoxyphenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7994 | 3-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7995 | 4-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7996 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7997 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7998 | 4-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_7999 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8000 | 3-(1-benzyl-1H-indol-3-yl)-2-(6-{[2-(1-benzyl-1H-indol-3-yl)-1-carboxyethyl]carbamoyl}-4-(2-{[2-(1-benzyl-1H-indol-3-yl)-1-carboxyethyl]carbamoyl}ethyl)-4-nitrohexanamido)propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8001 | 2-{6-[(1-carboxy-2-{1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}-3-{1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8002 | 4-{[3-(2-carboxy-2-{6-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}ethyl)-1H-indol-1-yl]methyl}benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8003 | 4-[(3-{2-carboxy-2-[3-(3-{2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethoxy}-2,2-bis({2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethoxy}methyl)propoxy)propanamido]ethyl}-1H-indol-1-yl)me | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8004 | 2-(6-{[1-carboxy-2-(2-phenyl-1H-indol-3-yl)ethyl]carbamoyl}-4-(2-{[1-carboxy-2-(2-phenyl-1H-indol-3-yl)ethyl]carbamoyl}ethyl)-4-nitrohexanamido)-3-(2-phenyl-1H-indol-3-yl)propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8005 | 2-[6-({1-carboxy-2-[2-(2-fluorophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(2-fluorophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(2-fluorophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8006 | 2-[6-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-nitrophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8007 | 3-[2-(4-bromophenyl)-1H-indol-3-yl]-2-[6-({2-[2-(4-bromophenyl)-1H-indol-3-yl]-1-carboxyethyl}carbamoyl)-4-[2-({2-[2-(4-bromophenyl)-1H-indol-3-yl]-1-carboxyethyl}carbamoyl)ethyl]-4-nitrohexanamido]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8008 | 2-{6-[(1-carboxy-2-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}-3-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8009 | 2-[6-({1-carboxy-2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-methoxyphenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8010 | 3-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8011 | 4-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8012 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8013 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8014 | 4-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8015 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8016 | 3-(1-benzyl-1H-indol-3-yl)-2-(6-{[2-(1-benzyl-1H-indol-3-yl)-1-carboxyethyl]carbamoyl}-4-(2-{[2-(1-benzyl-1H-indol-3-yl)-1-carboxyethyl]carbamoyl}ethyl)-4-nitrohexanamido)propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8017 | 2-{6-[(1-carboxy-2-{1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}-3-{1-[(4-fluorophenyl)methyl]-1H-indol-3-yl}propanoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8018 | 4-{[3-(2-carboxy-2-{6-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}ethyl)-1H-indol-1-yl]methyl}benzoic acid | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8019 | 4-[(3-{2-carboxy-2-[3-(3-{2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethoxy}-2,2-bis({2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethoxy}methyl)propoxy)propanamido]ethyl}-1H-indol-1-yl)me | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8020 | 2-(6-{[1-carboxy-2-(2-phenyl-1H-indol-3-yl)ethyl]carbamoyl}-4-(2-{[1-carboxy-2-(2-phenyl-1H-indol-3-yl)ethyl]carbamoyl}ethyl)-4-nitrohexanamido)-3-(2-phenyl-1H-indol-3-yl)propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8021 | 2-[6-({1-carboxy-2-[2-(2-fluorophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(2-fluorophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(2-fluorophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8022 | 2-[6-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-nitrophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8023 | 3-[2-(4-bromophenyl)-1H-indol-3-yl]-2-[6-({2-[2-(4-bromophenyl)-1H-indol-3-yl]-1-carboxyethyl}carbamoyl)-4-[2-({2-[2-(4-bromophenyl)-1H-indol-3-yl]-1-carboxyethyl}carbamoyl)ethyl]-4-nitrohexanamido]propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8024 | 2-{6-[(1-carboxy-2-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}ethyl)carbamoyl]-4-{2-[(1-carboxy-2-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}ethyl)carbamoyl]ethyl}-4-nitrohexanamido}-3-{2-[4-(trifluoromethyl)phenyl]-1H-indol-3-yl}propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8025 | 2-[6-({1-carboxy-2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-methoxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-methoxyphenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8026 | 3-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8027 | 4-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8028 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8029 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8030 | 4-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8031 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8032 | 4-[(3-{2-carboxy-2-[3-(3-{2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethoxy}-2,2-bis({2-[(1-carboxy-2-{1-[(4-carboxyphenyl)methyl]-1H-indol-3-yl}ethyl)carbamoyl]ethoxy}methyl)propoxy)propanamido]ethyl}-1H-indol-1-yl)me | NA | NA | Enterovirus | BrCr | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8033 | 2-[6-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(4-nitrophenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]-3-[2-(4-nitrophenyl)-1H-indol-3-yl]propanoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (90 %) | NA | 31809045 |
DrugRepV_8034 | 3-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (90 %) | NA | 31809045 |
DrugRepV_8035 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (90 %) | NA | 31809045 |
DrugRepV_8036 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (90 %) | NA | 31809045 |
DrugRepV_8037 | 4-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(4-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | BrCr | | NA | Decrease (90 %) | NA | 31809045 |
DrugRepV_8038 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Enterovirus | BrCr | | NA | Decrease (90 %) | NA | 31809045 |
DrugRepV_8039 | MADAL-385 | NA | NA | Enterovirus | 11316 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8040 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Enterovirus | 11316 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8041 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | 11316 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8042 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Enterovirus | 11316 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8043 | MADAL-385 | NA | NA | Enterovirus | TW/70902/08 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8044 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Enterovirus | TW/70902/08 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8045 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | TW/70902/08 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8046 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Enterovirus | TW/70902/08 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8047 | MADAL-385 | NA | NA | Enterovirus | H08300 461; 812 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8048 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Enterovirus | H08300 461; 812 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8049 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | H08300 461; 812 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8050 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Enterovirus | H08300 461; 812 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8051 | MADAL-385 | NA | NA | Enterovirus | TW/1956/05 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8052 | 5-(3-{2-carboxy-2-[6-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)-4-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethyl]-4-nitrohexanamido]ethyl}-1H-indol-2-yl)benzene-1,3-dicarboxylic acid | NA | NA | Enterovirus | TW/1956/05 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8053 | 3-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3-carboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzoic acid | NA | NA | Enterovirus | TW/1956/05 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8054 | 5-{3-[2-carboxy-2-(3-{3-[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]-2,2-bis({[2-({1-carboxy-2-[2-(3,5-dicarboxyphenyl)-1H-indol-3-yl]ethyl}carbamoyl)ethoxy]methyl})propoxy}propanamido)ethyl]-1H-indol-2-yl}benzene-1 | NA | NA | Enterovirus | TW/1956/05 | | NA | Decrease (50 %) | NA | 31809045 |
DrugRepV_8055 | 4-{[6-chloro-4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8056 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8057 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8058 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8059 | 4-{[6-chloro-4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8060 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8061 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8062 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8063 | 4-{[6-chloro-4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8064 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8065 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8066 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8067 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8068 | 4-{[4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8069 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8070 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8071 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8072 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8073 | 4-{[4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8074 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8075 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-hydroxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8076 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-nitroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8077 | 4-{[7-chloro-4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8078 | 4-{[7-chloro-4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8079 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8080 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8081 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8082 | 4-{[4-({2-amino-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-methylphenyl}amino)-7-chloroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8083 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8084 | 4-{[4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8085 | 4-{[4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8086 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8087 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8088 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8089 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8090 | 4-{[4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8091 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8092 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8093 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8094 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8095 | 4-{[4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8096 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8097 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-hydroxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8098 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-nitroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8099 | 4-{[7-chloro-4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8100 | 4-{[7-chloro-4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8101 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8102 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8103 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8104 | 4-{[4-({2-amino-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-methylphenyl}amino)-7-chloroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8105 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8106 | 4-{[4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8107 | 4-{[4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8108 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8109 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8110 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8111 | 4-{[6-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8112 | 4-{[4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8113 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8114 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8115 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)-6-fluoroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8116 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8117 | 4-{[4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8118 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-methoxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8119 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-hydroxyquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8120 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)-6-nitroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8121 | 4-{[7-chloro-4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8122 | 4-{[7-chloro-4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8123 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8124 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8125 | 4-{[7-chloro-4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8126 | 4-{[4-({2-amino-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-methylphenyl}amino)-7-chloroquinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8127 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8128 | 4-{[4-({2,6-dichloro-4-[(1E)-2-cyanoeth-1-en-1-yl]phenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8129 | 4-{[4-({2-chloro-4-[(1E)-2-cyanoeth-1-en-1-yl]-6-fluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8130 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-difluorophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8131 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-fluoro-6-methylphenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8132 | 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2-methyl-6-nitrophenyl}amino)quinazolin-2-yl]amino}benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | NA | Decrease (50 %) | NA | 31599568 |
DrugRepV_8133 | StemRegenin 1 | NA | NA | Vaccinia virus | NA | | NA | Decrease (68.1 %) | NA | 32708182 |
DrugRepV_8135 | ICG-001 | NA | NA | Vaccinia virus | NA | | NA | Decrease (80.9 %) | NA | 32708182 |
DrugRepV_8137 | NSC 319726 | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.8 %) | NA | 32708182 |
DrugRepV_8139 | RITA | NA | Cancer | Vaccinia virus | NA | | NA | Decrease (50.2 %) | NA | 32708182 |
DrugRepV_8143 | Monensin sodium salt | NA | NA | Vaccinia virus | NA | | NA | Decrease (96.7 %) | Experimental, Vet approved | 32708182 |
DrugRepV_8145 | 3-Deazaneplanocin A | NA | NA | Vaccinia virus | NA | | NA | Decrease (76.8 %) | NA | 32708182 |
DrugRepV_8148 | Azaguanine-8 | NA | NA | Vaccinia virus | NA | | NA | Decrease (12.7 %) | Experimental | 32708182 |
DrugRepV_8149 | Cytarabine | NA | Leukemia | Vaccinia virus | NA | | NA | Decrease (99.8 %) | Approved | 32708182 |
DrugRepV_8151 | Cyclocytidine Hydrochloride | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.8 %) | NA | 32708182 |
DrugRepV_8156 | Triapine | NA | Leukemia, Lung Cancer, Kidney Cancer, Prostate Cancer, and Pancreatic Cancer | Vaccinia virus | NA | | NA | Decrease (99.9 %) | Investigational | 32708182 |
DrugRepV_8158 | Apigenin | NA | NA | Vaccinia virus | NA | | NA | Decrease (54.8 %) | Experimental | 32708182 |
DrugRepV_8159 | Avasimibe | NA | Peripheral vascular disease | Vaccinia virus | NA | | NA | Decrease (50.9 %) | Investigational | 32708182 |
DrugRepV_8160 | Cyclosporin A | NA | Bone marrow transplant rejection | Vaccinia virus | NA | | NA | Decrease (67.2 %) | Approved, Investigational, Vet approved | 32708182 |
DrugRepV_8161 | ML130 | NA | NA | Vaccinia virus | NA | | NA | Decrease (35.9 %) | NA | 32708182 |
DrugRepV_8162 | PAC-1 | NA | Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers | Vaccinia virus | NA | | NA | Decrease (95.5 %) | Investigational | 32708182 |
DrugRepV_8163 | ABT-263 | NA | Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies | Vaccinia virus | NA | | NA | Decrease (33.1 %) | Investigational | 32708182 |
DrugRepV_8164 | ABT-737 | NA | NA | Vaccinia virus | NA | | NA | Decrease (26.6 %) | NA | 32708182 |
DrugRepV_8165 | PF-2545920 | NA | NA | Vaccinia virus | NA | | NA | Decrease (33.7 %) | NA | 32708182 |
DrugRepV_8168 | TPCA-1 | NA | NA | Vaccinia virus | NA | | NA | Decrease (78.5 %) | NA | 32708182 |
DrugRepV_8170 | PTC-209 | NA | NA | Vaccinia virus | NA | | NA | Decrease (90.7 %) | NA | 32708182 |
DrugRepV_8171 | Selisistat | NA | NA | Vaccinia virus | NA | | NA | Decrease (30.5 %) | NA | 32708182 |
DrugRepV_8172 | Salinomycin | NA | NA | Vaccinia virus | NA | | NA | Decrease (92.5 %) | Vet approved | 32708182 |
DrugRepV_8173 | Dapivirine | NA | Acquired immunodeficiency syndrome | Vaccinia virus | NA | | NA | Decrease (41.7 %) | Investigational | 32708182 |
DrugRepV_8174 | CCG 50014 | NA | NA | Vaccinia virus | NA | | NA | Decrease (35.8 %) | NA | 32708182 |
DrugRepV_8175 | Mocetinostat | NA | Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma | Vaccinia virus | NA | | NA | Decrease (46.9 %) | Investigational | 32708182 |
DrugRepV_8177 | UK 383367 | NA | NA | Vaccinia virus | NA | | NA | Decrease (17 %) | NA | 32708182 |
DrugRepV_8178 | Lonafarnib | NA | Solid tumors, leukemia (unspecified), and lung cancer | Vaccinia virus | NA | | NA | Decrease (36.2 %) | Investigational | 32708182 |
DrugRepV_8179 | BX-912 | NA | NA | Vaccinia virus | NA | | NA | Decrease (42.3 %) | NA | 32708182 |
DrugRepV_8180 | URB597 | NA | NA | Vaccinia virus | NA | | NA | Decrease (21.7 %) | NA | 32708182 |
DrugRepV_8181 | Anagrelide HCl | NA | NA | Vaccinia virus | NA | | NA | Decrease (58.4 %) | NA | 32708182 |
DrugRepV_8185 | Ganetespib | NA | BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid Leukaemia, and Myelodysplastic Syndrome | Vaccinia virus | NA | | NA | Decrease (99.7 %) | Investigational | 32708182 |
DrugRepV_8186 | PF-04929113 | NA | Cancer/tumors | Vaccinia virus | NA | | NA | Decrease (99.4 %) | Investigational | 32708182 |
DrugRepV_8187 | NMS-E973 | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.1 %) | NA | 32708182 |
DrugRepV_8188 | XL888 | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.6 %) | NA | 32708182 |
DrugRepV_8189 | Tanespimycin | NA | Leukemia (myeloid) and solid tumors. | Vaccinia virus | NA | | NA | Decrease (99.4 %) | Investigational | 32708182 |
DrugRepV_8190 | VER-49009 | NA | NA | Vaccinia virus | NA | | NA | Decrease (98.9 %) | NA | 32708182 |
DrugRepV_8191 | SNX2112 | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.4 %) | NA | 32708182 |
DrugRepV_8192 | BIIB021 | NA | Tumors and Lymphoma | Vaccinia virus | NA | | NA | Decrease (99.8 %) | Investigational | 32708182 |
DrugRepV_8194 | NVP-BEP800 | NA | NA | Vaccinia virus | NA | | NA | Decrease (98.8 %) | NA | 32708182 |
DrugRepV_8195 | AUY922 | NA | Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms | Vaccinia virus | NA | | NA | Decrease (99.8 %) | Investigational | 32708182 |
DrugRepV_8196 | KW-2478 | NA | NA | Vaccinia virus | NA | | NA | Decrease (92.7 %) | NA | 32708182 |
DrugRepV_8198 | ABT-751 | NA | Lung Cancer | Vaccinia virus | NA | | NA | Decrease (81.5 %) | Investigational | 32708182 |
DrugRepV_8199 | Epothilone A | NA | NA | Vaccinia virus | NA | | NA | Decrease (27.3 %) | NA | 32708182 |
DrugRepV_8200 | Amygdalin | NA | NA | Vaccinia virus | NA | | NA | Decrease (58.3 %) | NA | 32708182 |
DrugRepV_8201 | Kaempferol | NA | NA | Vaccinia virus | NA | | NA | Decrease (64.7 %) | NA | 32708182 |
DrugRepV_8202 | ENMD-2076 | NA | Breast cancer, leukemia (unspecified), lung cancer, and solid tumors | Vaccinia virus | NA | | NA | Decrease (72.3 %) | Investigational | 32708182 |
DrugRepV_8203 | AMG-900 | NA | NA | Vaccinia virus | NA | | NA | Decrease (50.4 %) | NA | 32708182 |
DrugRepV_8204 | MLN8054 | NA | Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies | Vaccinia virus | NA | | NA | Decrease (36.2 %) | Investigational | 32708182 |
DrugRepV_8205 | Ibrutinib | NA | Mantle cell lymphoma | Vaccinia virus | NA | | NA | Decrease (74.9 %) | Approved | 32708182 |
DrugRepV_8206 | CNX-774 | NA | NA | Vaccinia virus | NA | | NA | Decrease (70 %) | NA | 32708182 |
DrugRepV_8207 | AR-A014418 | NA | NA | Vaccinia virus | NA | | NA | Decrease (47.9 %) | Experimental | 32708182 |
DrugRepV_8208 | CGP 57380 | NA | NA | Vaccinia virus | NA | | NA | Decrease (58.1 %) | NA | 32708182 |
DrugRepV_8210 | HMN-214 | NA | NA | Vaccinia virus | NA | | NA | Decrease (58.9 %) | NA | 32708182 |
DrugRepV_8211 | TG003 | NA | NA | Vaccinia virus | NA | | NA | Decrease (46.7 %) | NA | 32708182 |
DrugRepV_8212 | Skepinone-L | NA | NA | Vaccinia virus | NA | | NA | Decrease (47.1 %) | NA | 32708182 |
DrugRepV_8213 | TAK-632 | NA | NA | Vaccinia virus | NA | | NA | Decrease (65.2 %) | NA | 32708182 |
DrugRepV_8214 | YM201636 | NA | NA | Vaccinia virus | NA | | NA | Decrease (56.3 %) | NA | 32708182 |
DrugRepV_8215 | MK-2461 | NA | NA | Vaccinia virus | NA | | NA | Decrease (57 %) | NA | 32708182 |
DrugRepV_8217 | SP600125 | NA | NA | Vaccinia virus | NA | | NA | Decrease (50.5 %) | NA | 32708182 |
DrugRepV_8218 | SKI II | NA | NA | Vaccinia virus | NA | | NA | Decrease (65.1 %) | NA | 32708182 |
DrugRepV_8219 | PKI-402 | NA | NA | Vaccinia virus | NA | | NA | Decrease (44.9 %) | NA | 32708182 |
DrugRepV_8220 | BEZ235 | NA | Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome | Vaccinia virus | NA | | NA | Decrease (37.4 %) | Investigational | 32708182 |
DrugRepV_8221 | WYE-125132 | NA | NA | Vaccinia virus | NA | | NA | Decrease (67.6 %) | NA | 32708182 |
DrugRepV_8222 | OSI-027 | NA | NA | Vaccinia virus | NA | | NA | Decrease (68.3 %) | Investigational | 32708182 |
DrugRepV_8223 | Torin 1 | NA | NA | Vaccinia virus | NA | | NA | Decrease (57.3 %) | NA | 32708182 |
DrugRepV_8224 | Ku-0063794 | NA | NA | Vaccinia virus | NA | | NA | Decrease (55.3 %) | NA | 32708182 |
DrugRepV_8225 | AZD2014 | NA | Advanced Gastric Adenocarcinoma | Vaccinia virus | NA | | NA | Decrease (70.3 %) | Investigational | 32708182 |
DrugRepV_8228 | KX2-391 | NA | Colon cancer | Pancreatic cancer | Prostate cancer | Breast cancer | Vaccinia virus | NA | | NA | Decrease (65.1 %) | Investigational | 32708182 |
DrugRepV_8230 | PP1 | NA | NA | Vaccinia virus | NA | | NA | Decrease (35.8 %) | NA | 32708182 |
DrugRepV_8231 | AZ 960 | NA | NA | Vaccinia virus | NA | | NA | Decrease (82.1 %) | NA | 32708182 |
DrugRepV_8232 | LY2784544 | NA | Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders | Vaccinia virus | NA | | NA | Decrease (65.7 %) | Investigational | 32708182 |
DrugRepV_8233 | WHI-P154 | NA | NA | Vaccinia virus | NA | | NA | Decrease (66.3 %) | NA | 32708182 |
DrugRepV_8234 | Cyt387 | NA | Polycythemia Vera, Primary Myelofibrosis, Post-Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofibrosis (PMF) | Vaccinia virus | NA | | NA | Decrease (45.2 %) | Investigational | 32708182 |
DrugRepV_8235 | KPT-276 | NA | NA | Vaccinia virus | NA | | NA | Decrease (27.6 %) | NA | 32708182 |
DrugRepV_8236 | KPT-185 | NA | NA | Vaccinia virus | NA | | NA | Decrease (26.2 %) | NA | 32708182 |
DrugRepV_8237 | Phloretin | NA | NA | Vaccinia virus | NA | | NA | Decrease (-27 %) | Experimental | 32708182 |
DrugRepV_8242 | SC144 | NA | NA | Vaccinia virus | NA | | NA | Decrease (98.4 %) | NA | 32708182 |
DrugRepV_8243 | Daidzein | NA | Dietary supplement | Vaccinia virus | NA | | NA | Decrease (32.2 %) | Experimental | 32708182 |
DrugRepV_8244 | Delanzomib | NA | Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin. | Vaccinia virus | NA | | NA | Decrease (99.7 %) | Investigational | 32708182 |
DrugRepV_8245 | MLN9708 | NA | Multiple myeloma | Vaccinia virus | NA | | NA | Decrease (99.6 %) | Approved, Investigational | 32708182 |
DrugRepV_8246 | Oprozomib | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.5 %) | Investigational | 32708182 |
DrugRepV_8247 | MG-132 | NA | NA | Vaccinia virus | NA | | NA | Decrease (98.9 %) | NA | 32708182 |
DrugRepV_8248 | MLN2238 | NA | Multiple myeloma | Vaccinia virus | NA | | NA | Decrease (99.7 %) | Approved, Investigational | 32708182 |
DrugRepV_8249 | ONX-0914 | NA | NA | Vaccinia virus | NA | | NA | Decrease (99.5 %) | NA | 32708182 |
DrugRepV_8250 | Amonafide | NA | Breast cancer, ovarian cancer, and prostate cancer | Vaccinia virus | NA | | NA | Decrease (99.3 %) | Investigational | 32708182 |
DrugRepV_8253 | Golvatinib | NA | Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck | Vaccinia virus | NA | | NA | Decrease (79.8 %) | Investigational | 32708182 |
DrugRepV_8255 | AG 1296 | NA | NA | Vaccinia virus | NA | | NA | Decrease (53.2 %) | NA | 32708182 |
DrugRepV_8256 | NVP-TAE226 | NA | NA | Vaccinia virus | NA | | NA | Decrease (91.5 %) | NA | 32708182 |
DrugRepV_8257 | Cabozantinib malate | NA | Metastatic medullary thyroid cancer | Vaccinia virus | NA | | NA | Decrease (79.3 %) | NA | 32708182 |
DrugRepV_8258 | XL-184 | NA | Thyroid cancer | Vaccinia virus | NA | | NA | Decrease (64.2 %) | Approved, Investigational | 32708182 |
DrugRepV_8259 | Linifanib | NA | NA | Vaccinia virus | NA | | NA | Decrease (60.5 %) | NA | 32708182 |
DrugRepV_8260 | TKI-258 | NA | Multiple myeloma and solid tumors | Vaccinia virus | NA | | NA | Decrease (67.6 %) | Investigational | 32708182 |
DrugRepV_8261 | AZD4547 | NA | Cancer | Vaccinia virus | NA | | NA | Decrease (81.5 %) | Investigational | 32708182 |
DrugRepV_8262 | AG-1024 | NA | NA | Vaccinia virus | NA | | NA | Decrease (71.8 %) | NA | 32708182 |
DrugRepV_8263 | BMS-754807 | NA | Solid Tumors | Vaccinia virus | NA | | NA | Decrease (61.8 %) | Investigational | 32708182 |
DrugRepV_8265 | Butein | NA | NA | Vaccinia virus | NA | | NA | Decrease (62.6 %) | NA | 32708182 |
DrugRepV_8266 | CO-1686 (AVL-301) | NA | Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer | Vaccinia virus | NA | | NA | Decrease (74.3 %) | NA | 32708182 |
DrugRepV_8267 | PD168393 | NA | NA | Vaccinia virus | NA | | NA | Decrease (67.2 %) | Experimental | 32708182 |
DrugRepV_8268 | PD153035 HCl | NA | NA | Vaccinia virus | NA | | NA | Decrease (74.7 %) | NA | 32708182 |
DrugRepV_8270 | Desmethyl Erlotinib | NA | Cancer | Vaccinia virus | NA | | NA | Decrease (75.5 %) | Approved, Investigational | 32708182 |
DrugRepV_8271 | OSI-420 | NA | NA | Vaccinia virus | NA | | NA | Decrease (46.7 %) | NA | 32708182 |
DrugRepV_8274 | WZ8040 | NA | NA | Vaccinia virus | NA | | NA | Decrease (96.4 %) | NA | 32708182 |
DrugRepV_8282 | 1-(2-fluorophenyl)-3-(4-(4-isopentyl-1H-1,2,3-triazol-1-yl)phenyl)urea | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8283 | 1-(3-fluorophenyl)-3-(4-(4-isopentyl-1H-1,2,3-triazol-1-yl)phenyl)urea | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8284 | 1-(4-(4-(ethoxymethyl)-1H-1,2,3-triazol-1-yl)phenyl)-3-(3-fluorophenyl)urea | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8285 | 1-(3-fluorophenyl)-3-(4-(4-(3-oxobutyl)-1H-1,2,3-triazol-1-yl)phenyl)urea | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8286 | 1-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)-3-(3-fluorophenyl)urea | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8287 | N-(2-(3-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)ureido)phenyl)methanesulfonamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8288 | 1-(4-(4-isopentyl-1H-1,2,3-triazol-1-yl)phenyl)-3-o-tolylurea | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8289 | 1-(4-(4-hexyl-1H-1,2,3-triazol-1-yl)phenyl)-3-(2-(trifluoromethyl)phenyl)urea) | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8290 | 3-(4-(ethoxymethyl)-1H-1,2,3-triazol-1-yl)-N-(2-morpholinophenyl)benzenesulfonamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8291 | ethyl 3-((3-(4-(ethoxymethyl)-1H-1,2,3-triazol-1-yl)phenyl)sulfonamido)benzoate | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8292 | 3-((3-(4-(ethoxymethyl)-1H-1,2,3-triazol-1-yl)phenyl)sulfonamido)benzoic acid | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8293 | 3-(4-butyl-1H-1,2,3-triazol-1-yl)-N-(2-(methylsulfonamido)phenyl)benzenesulfonamide | NA | NA | Dengue virus | NA | | NA | Decrease (50 %) | NA | 32435411 |
DrugRepV_8315 | Tenatoprazole | NA | NA | Human immunodeficiency virus | NA | | Western blot | Decrease (50 %) | NA | 32132561 |
DrugRepV_8317 | Roscovitine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31866007 |
DrugRepV_8318 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Investigational | 31866007 |
DrugRepV_8319 | Kenpaullone | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31866007 |
DrugRepV_8320 | SB743921 | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31866007 |
DrugRepV_8321 | 3-Deazauridine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31866007 |
DrugRepV_8322 | 2’-C-Methylcytidine | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 31866007 |
DrugRepV_8323 | Alisporivir | NA | Hepatitis C virus | SARS Coronavirus-2 | Experimental | NA | Viral RNA reduction assay | Decrease (50 %) | Investigational | 32376613 |
DrugRepV_8324 | Alisporivir | NA | Hepatitis C virus | SARS Coronavirus-2 | Experimental | NA | Viral RNA reduction assay | Decrease (90 %) | Investigational | 32376613 |
DrugRepV_8327 | 4-ethynyl-2-fluoro-2-deoxyadenosine | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8328 | Alovudine | NA | HIV | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Investigational | 32429580 |
DrugRepV_8329 | 5-O-(12-thioethydodecanoyl)FLT | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8331 | 5-O-(tetradecanoyl)3TC | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8333 | 5-O-(tetradecanoyl)FTC | NA | NA | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | NA | 32429580 |
DrugRepV_8335 | Nafamostat | NA | Blood vessel coagulation | Hemorrhagic lesions | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | Investigational | 32596694 |
DrugRepV_8337 | Gabexate | NA | Cancer, ischemia-reperfusion injury, and pancreatitis | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Investigational | 32596694 |
DrugRepV_8339 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8340 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8341 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8342 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8343 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8344 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8345 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8346 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8347 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8348 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8349 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8350 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8351 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8352 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8353 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8354 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8355 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8356 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8357 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8358 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8359 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8360 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8361 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8362 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8363 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8364 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8365 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8366 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | E138K | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8367 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8368 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8369 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8370 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8371 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8372 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8373 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8374 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8375 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8376 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8377 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8378 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8379 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8380 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | L100I | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8381 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8382 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8383 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8384 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8385 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8386 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8387 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8388 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8389 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8390 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8391 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8392 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8393 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8394 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | K103N | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8395 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8396 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8397 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8398 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8399 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8400 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8401 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8402 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8403 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8404 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8405 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8406 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8407 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8408 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y181C | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8409 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8410 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8411 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8412 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8413 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8414 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8415 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8416 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8417 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8418 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8419 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8420 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8421 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8422 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | Y188L | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8423 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8424 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8425 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8426 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8427 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8428 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8429 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8430 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8431 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8432 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8433 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8434 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8435 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8436 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | F227L + V106A | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8437 | ((4-((3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8438 | ((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8439 | ((4-((3,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8440 | 4-((4-((2,3-difluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8441 | ((4-((3-fluoro-2-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8442 | ((4-((3-fluoro-3-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8443 | ((4-((3-fluoro-4-methyl-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8444 | ((4-((3-fluoro-2-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino) methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8445 | ((4-((3-fluoro-3-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8446 | ((4-((3-fluoro-4-methoxy-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8447 | ((4-((2-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino) benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8448 | ((4-((4-chloro-3-fluoro-[1,1-biphenyl]-4-yl)(hydroxyimino)methyl)pyrimidin-2-yl)amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8449 | ((4-((3-fluoro-2-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8450 | ((4-((3-fluoro-4-(trifluoromethyl)-[1,1-biphenyl]-4-yl)(hydroxylimino)methyl)pyrimidin-2-yl) amino)benzonitrile | NA | NA | Human immunodeficiency virus | RES056 | | MTT assay | Decrease (50 %) | NA | 32334191 |
DrugRepV_8456 | Berberine Chloride | NA | NA | Zika virus | NA | NA | NA | Decrease (50 %) | NA | 29844387 |
DrugRepV_8457 | Berberine | NA | Parasitic and fungal infection | Zika virus | NA | NA | Plaque assay | Decrease (50 %) | Approved | 30641880 |
DrugRepV_8458 | Emodin | NA | Polycystic Kidney | Zika virus | NA | NA | Plaque assay | Decrease (50 %) | Investigational | 30641880 |
DrugRepV_8459 | Berberine | NA | Parasitic and fungal infection | Enterovirus | H | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8460 | Berberine | NA | Parasitic and fungal infection | Enterovirus | SHZH98 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8461 | Berberine | NA | Parasitic and fungal infection | Enterovirus | JS-52 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8462 | Berberine | NA | Parasitic and fungal infection | Enterovirus | BrCr | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28081706 |
DrugRepV_8463 | Pirodavir | NA | Picronavirus infection | Enterovirus | H | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8464 | Pirodavir | NA | Picronavirus infection | Enterovirus | SHZH98 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8465 | Pirodavir | NA | Picronavirus infection | Enterovirus | JS-52 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8466 | Pirodavir | NA | Picronavirus infection | Enterovirus | BrCr | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Experimental | 28081706 |
DrugRepV_8467 | Berberine | NA | Parasitic and fungal infection | Influenza virus | NA | | XTT assay | Decrease (50 %) | Approved | 32245183 |
DrugRepV_8468 | Berberine | NA | Parasitic and fungal infection | Influenza virus | NA | | XTT assay | Decrease (50 %) | Approved | 32245183 |
DrugRepV_8469 | Berberine | NA | Parasitic and fungal infection | Influenza virus | NA | | XTT assay | Decrease (50 %) | Approved | 32245183 |
DrugRepV_8470 | Berberine | NA | Parasitic and fungal infection | Influenza virus | NA | | XTT assay | Decrease (50 %) | Approved | 32245183 |
DrugRepV_8471 | Berberine | NA | Parasitic and fungal infection | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Approved | 21295891 |
DrugRepV_8472 | Berberine | NA | Parasitic and fungal infection | Influenza virus | NA | | NA | Decrease (50 %) | Approved | 30099043 |
DrugRepV_8473 | Ebselen | NA | Meniere Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Investigational | 23850693 |
DrugRepV_8474 | 2-Phenylbenzo[d]isothiazol-3(2H)-one | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8475 | 2-Phenylbenzo[d] isoxazol-3(2H)-one | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8476 | 2-Phenyl isoindolin-1-one | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8477 | Chelerythrine chloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8478 | Nitidine chloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8479 | Berberine chloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8480 | Sanguinarine chloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8481 | Norsanguinarine chloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8482 | R-Apomorphine hydrochloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8483 | S-Apomorphine hydrochloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8484 | R(?)-Propylnorapomorphine hydrochloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |
DrugRepV_8485 | R(?)-Apocodeine hydrochloride | NA | NA | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | NA | 23850693 |