Chemical Information | |
Antiviral agent ID | DrugRepV_4565 | |
Antiviral agent name | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-nitrophenyl)methoxy]-4H-chromen-4-one | |
IUPAC Name | 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-nitrophenyl)methoxy]-4H-chromen-4-one | |
SMILES (canonical) | OC1=CC=C(C=C1O)C1=C(O)C(=O)C2=C(O1)C=C(OCC1=CC=CC(=C1)N(=O)=O)C=C2O | |
Molecular Formula | C22H15NO9 | |
Molecular Weight (g/mol) | 437.36 | |
InChl | InChI=1S/C22H15NO9/c24-15-5-4-12(7-16(15)25)22-21(28)20(27)19-17(26)8-14(9-18(19)32-22)31-10-11-2-1-3-13(6-11)23(29)30/h1-9,24-26,28H,10H2 | |
Structural Information | |
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Clinical Information | |
Biological Information | |
Secondary Indication | Severe acute respiratory syndrome coronavirus (SARS-CoV) NA NA | |
Secondary Indication (Approaches) | Experimental | |
Secondary Indication (Methods) | In-vitro | |
Secondary Indication (Mode of drug delivery) | Culture
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Secondary Indication (Drug concentration) | >50 μM
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Secondary Indication (Change) | Decrease
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Secondary Indication (Type of Inhibition) | IC50 [ 50 % ] | |
Reference | Park HR, Yoon H, Kim MK, Lee SD, Chong Y..Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV)..Arch Pharm Res. 2012 Jan;35(1):77-85. doi: 10.1007/s12272-012-0108-9. Epub 2012 Feb 2. PMID:22297745
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Comment | NA
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