Chemical, Structural, Clinical and Biological details of Antiviral agents ID: DrugRepV_4565



Chemical Information
Antiviral agent IDDrugRepV_4565
Antiviral agent name2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-nitrophenyl)methoxy]-4H-chromen-4-one
IUPAC Name2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-[(3-nitrophenyl)methoxy]-4H-chromen-4-one PubChem
SMILES (canonical)OC1=CC=C(C=C1O)C1=C(O)C(=O)C2=C(O1)C=C(OCC1=CC=CC(=C1)N(=O)=O)C=C2O PubChem
Molecular FormulaC22H15NO9 PubChem
Molecular Weight (g/mol)437.36 PubChem
InChlInChI=1S/C22H15NO9/c24-15-5-4-12(7-16(15)25)22-21(28)20(27)19-17(26)8-14(9-18(19)32-22)31-10-11-2-1-3-13(6-11)23(29)30/h1-9,24-26,28H,10H2 PubChem
Structural Information
  
Clinical Information
Biological Information
Secondary Indication Severe acute respiratory syndrome coronavirus (SARS-CoV) NA NAWorld Health OrganisationCDC
Secondary Indication (Approaches)Experimental
Secondary Indication (Methods)In-vitro
Secondary Indication (Mode of drug delivery) Culture
Secondary Indication (Drug concentration)>50 μM
Secondary Indication (Change)Decrease
Secondary Indication (Type of Inhibition) IC50 [ 50 % ]
ReferencePark HR, Yoon H, Kim MK, Lee SD, Chong Y..Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV)..Arch Pharm Res. 2012 Jan;35(1):77-85. doi: 10.1007/s12272-012-0108-9. Epub 2012 Feb 2. PMID:22297745 PubMed
CommentNA