HPVomics

A therapeutic and epitome resource for Human Papillomaviruses

Efficient putative LR-HPVs E2 protein epitopes (MHC-II Binders)

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S.No.	HPV type	Target region	Peptide seuences	Start	End	Allele	Method	Percentile rank
1	HPV43	E2	LKCFRYRLNKHKHLF	302	316	HLA-DRB5*01:01	Consensus	0.04
2	HPV43	E2	ALKCFRYRLNKHKHL	301	315	HLA-DRB5*01:01	Consensus	0.07
3	HPV43	E2	KCFRYRLNKHKHLFA	303	317	HLA-DRB5*01:01	Consensus	0.07
4	HPV61	E2	HWHYVRLENAMLFKA	34	48	HLA-DRB1*01:01	Consensus	0.09
5	HPV54	E2	IVHFKGEPNTLKCFR	289	303	HLA-DRB5*01:01	Consensus	0.11
6	HPV61	E2	QILHWHYVRLENAML	31	45	HLA-DRB1*04:05	Consensus	0.11
7	HPV61	E2	ILHWHYVRLENAMLF	32	46	HLA-DRB1*04:05	Consensus	0.11
8	HPV72	E2	CFRYRLQQSVPNLFL	316	330	HLA-DRB1*07:01	Consensus	0.11
9	HPV43	E2	NALKCFRYRLNKHKH	300	314	HLA-DRB5*01:01	Consensus	0.13
10	HPV43	E2	CFRYRLNKHKHLFAD	304	318	HLA-DRB5*01:01	Consensus	0.15
11	HPV61	E2	LHWHYVRLENAMLFK	33	47	HLA-DRB1*04:05	Consensus	0.15
12	HPV72	E2	KCFRYRLQQSVPNLF	315	329	HLA-DRB1*07:01	Consensus	0.15
13	HPV54	E2	VHFKGEPNTLKCFRQ	290	304	HLA-DRB5*01:01	Consensus	0.18
14	HPV61	E2	LHWHYVRLENAMLFK	33	47	HLA-DRB1*01:01	Consensus	0.19
15	HPV61	E2	WHYVRLENAMLFKAR	35	49	HLA-DRB1*01:01	Consensus	0.19
16	HPV72	E2	FRYRLQQSVPNLFLK	317	331	HLA-DRB1*07:01	Consensus	0.2
17	HPV54	E2	PIVHFKGEPNTLKCF	288	302	HLA-DRB5*01:01	Consensus	0.23
18	HPV72	E2	QQARDICNSHGAPII	291	305	HLA-DRB1*13:02	Consensus	0.25
19	HPV72	E2	QARDICNSHGAPIIH	292	306	HLA-DRB1*13:02	Consensus	0.25
20	HPV72	E2	ARDICNSHGAPIIHL	293	307	HLA-DRB1*13:02	Consensus	0.25
21	HPV72	E2	RDICNSHGAPIIHLK	294	308	HLA-DRB1*13:02	Consensus	0.25
22	HPV40	E2	QRSDFLAIVKIPKTI	346	360	HLA-DRB5*01:01	Consensus	0.26
23	HPV40	E2	RSDFLAIVKIPKTIK	347	361	HLA-DRB5*01:01	Consensus	0.26
24	HPV40	E2	SDFLAIVKIPKTIKH	348	362	HLA-DRB5*01:01	Consensus	0.26
25	HPV40	E2	VQQRSDFLAIVKIPK	344	358	HLA-DRB1*11:01	Consensus	0.26
26	HPV40	E2	QQRSDFLAIVKIPKT	345	359	HLA-DRB1*11:01	Consensus	0.26
27	HPV40	E2	QRSDFLAIVKIPKTI	346	360	HLA-DRB1*11:01	Consensus	0.26
28	HPV40	E2	RSDFLAIVKIPKTIK	347	361	HLA-DRB1*11:01	Consensus	0.26
29	HPV40	E2	SDFLAIVKIPKTIKH	348	362	HLA-DRB1*11:01	Consensus	0.26
30	HPV40	E2	DFLAIVKIPKTIKHS	349	363	HLA-DRB1*11:01	Consensus	0.26
31	HPV40	E2	FLAIVKIPKTIKHSL	350	364	HLA-DRB1*11:01	Consensus	0.26
32	HPV40	E2	FLAIVKIPKTIKHSL	350	364	HLA-DRB5*01:01	Consensus	0.26
33	HPV42	E2	EAQRNLFLNTVKIPS	369	383	HLA-DRB1*11:01	Consensus	0.26
34	HPV42	E2	AQRNLFLNTVKIPSG	370	384	HLA-DRB1*11:01	Consensus	0.26
35	HPV42	E2	QRNLFLNTVKIPSGI	371	385	HLA-DRB1*11:01	Consensus	0.26
36	HPV42	E2	RNLFLNTVKIPSGIK	372	386	HLA-DRB1*11:01	Consensus	0.26
37	HPV42	E2	NLFLNTVKIPSGIKS	373	387	HLA-DRB1*11:01	Consensus	0.26
38	HPV43	E2	ANALKCFRYRLNKHK	299	313	HLA-DRB5*01:01	Consensus	0.26
39	HPV61	E2	HWHYVRLENAMLFKA	34	48	HLA-DRB1*04:05	Consensus	0.26
40	HPV61	E2	WHYVRLENAMLFKAR	35	49	HLA-DRB1*04:05	Consensus	0.26
41	HPV44	E2	SSSSTTTTLAQASST	215	229	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.29
42	HPV44	E2	HSSSSTTTTLAQASS	214	228	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.3
43	HPV44	E2	SSSTTTTLAQASSTL	216	230	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.3
44	HPV43	E2	FRYRLNKHKHLFADV	305	319	HLA-DRB5*01:01	Consensus	0.31
45	HPV44	E2	SHSSSSTTTTLAQAS	213	227	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.35
46	HPV54	E2	HFKGEPNTLKCFRQR	291	305	HLA-DRB5*01:01	Consensus	0.37
47	HPV44	E2	AKYKTLFVAASSTWR	316	330	HLA-DRB5*01:01	Consensus	0.38
48	HPV44	E2	KYKTLFVAASSTWRW	317	331	HLA-DRB5*01:01	Consensus	0.38
49	HPV44	E2	YKTLFVAASSTWRWT	318	332	HLA-DRB5*01:01	Consensus	0.38
50	HPV44	E2	KTLFVAASSTWRWTC	319	333	HLA-DRB5*01:01	Consensus	0.38
51	HPV44	E2	TLFVAASSTWRWTCS	320	334	HLA-DRB5*01:01	Consensus	0.38
52	HPV44	E2	LFVAASSTWRWTCSD	321	335	HLA-DRB5*01:01	Consensus	0.38
53	HPV44	E2	FVAASSTWRWTCSDT	322	336	HLA-DRB5*01:01	Consensus	0.38
54	HPV61	E2	HYVRLENAMLFKARQ	36	50	HLA-DRB1*01:01	Consensus	0.39
55	HPV72	E2	RYRLQQSVPNLFLKA	318	332	HLA-DRB1*07:01	Consensus	0.4
56	HPV70	E2	RYRLRKFNSLYENIS	297	311	HLA-DRB1*04:05	Consensus	0.41
57	HPV54	E2	TPIVHFKGEPNTLKC	287	301	HLA-DRB5*01:01	Consensus	0.42
58	HPV70	E2	YRLRKFNSLYENISC	298	312	HLA-DRB1*04:05	Consensus	0.42
59	HPV72	E2	TQQARDICNSHGAPI	290	304	HLA-DRB1*13:02	Consensus	0.45
60	HPV61	E2	ILHWHYVRLENAMLF	32	46	HLA-DRB1*01:01	Consensus	0.47
61	HPV70	E2	YWKYVRLENAIFYAA	37	51	HLA-DRB1*04:05	Consensus	0.47
62	HPV70	E2	WKYVRLENAIFYAAR	38	52	HLA-DRB1*04:05	Consensus	0.47
63	HPV70	E2	NYWKYVRLENAIFYA	36	50	HLA-DRB1*04:05	Consensus	0.49
64	HPV70	E2	QINYWKYVRLENAIF	34	48	HLA-DRB1*04:05	Consensus	0.5
65	HPV70	E2	INYWKYVRLENAIFY	35	49	HLA-DRB1*04:05	Consensus	0.5
66	HPV44	E2	PKVTYKVGYMSLQLL	363	377	HLA-DRB4*01:01	Consensus	0.51
67	HPV43	E2	CFRYRLNKHKHLFAD	304	318	HLA-DRB1*11:01	Consensus	0.52
68	HPV70	E2	YWKYVRLENAIFYAA	37	51	HLA-DRB1*01:01	Consensus	0.54
69	HPV72	E2	IIHLKGEPNKLKCFR	304	318	HLA-DRB5*01:01	Consensus	0.54
70	HPV43	E2	FRYRLNKHKHLFADV	305	319	HLA-DRB1*11:01	Consensus	0.63
71	HPV54	E2	LKCFRQRIQKYKHLF	299	313	HLA-DRB5*01:01	Consensus	0.63
72	HPV43	E2	KCFRYRLNKHKHLFA	303	317	HLA-DRB1*11:01	Consensus	0.69
73	HPV54	E2	TTPIVHFKGEPNTLK	286	300	HLA-DRB5*01:01	Consensus	0.69
74	HPV54	E2	FKGEPNTLKCFRQRI	292	306	HLA-DRB5*01:01	Consensus	0.69
75	HPV72	E2	QQARDICNSHGAPII	291	305	HLA-DRB1*07:01	Consensus	0.7
76	HPV72	E2	YRLQQSVPNLFLKAS	319	333	HLA-DRB1*07:01	Consensus	0.7
77	HPV81	E2	ANKLKCLRYRLRSSV	305	319	HLA-DRB1*11:01	Consensus	0.72
78	HPV61	E2	KCFRYRLQHSVPELF	313	327	HLA-DRB1*07:01	Consensus	0.73
79	HPV61	E2	QILHWHYVRLENAML	31	45	HLA-DRB1*01:01	Consensus	0.77
80	HPV72	E2	IHLKGEPNKLKCFRY	305	319	HLA-DRB5*01:01	Consensus	0.78
81	HPV54	E2	TLKCFRQRIQKYKHL	298	312	HLA-DRB5*01:01	Consensus	0.81
82	HPV81	E2	NKLKCLRYRLRSSVP	306	320	HLA-DRB1*11:01	Consensus	0.81
83	HPV42	E2	TAWTYIYIQTVQGTW	132	146	HLA-DRB4*01:01	Consensus	0.85
84	HPV42	E2	AYNVPIQTSPPRKRY	246	260	HLA-DRB5*01:01	Consensus	0.86
85	HPV42	E2	YNVPIQTSPPRKRYR	247	261	HLA-DRB5*01:01	Consensus	0.86
86	HPV42	E2	NVPIQTSPPRKRYRQ	248	262	HLA-DRB5*01:01	Consensus	0.86
87	HPV42	E2	VPIQTSPPRKRYRQC	249	263	HLA-DRB5*01:01	Consensus	0.86
88	HPV61	E2	YVRLENAMLFKARQA	37	51	HLA-DRB1*01:01	Consensus	0.88
89	HPV72	E2	TQQARDICNSHGAPI	290	304	HLA-DRB1*07:01	Consensus	0.94
90	HPV70	E2	KNGLKCLRYRLRKFN	290	304	HLA-DRB1*11:01	Consensus	0.99
91	HPV61	E2	HWHYVRLENAMLFKA	34	48	HLA-DRB3*02:02	NetMHCIIpan	0.03
92	HPV61	E2	WHYVRLENAMLFKAR	35	49	HLA-DRB3*02:02	NetMHCIIpan	0.03
93	HPV72	E2	FRYRLQQSVPNLFLK	317	331	HLA-DRB3*02:02	NetMHCIIpan	0.03
94	HPV61	E2	LHWHYVRLENAMLFK	33	47	HLA-DRB3*02:02	NetMHCIIpan	0.04
95	HPV72	E2	HWHYVRLEHAMLFKA	34	48	HLA-DRB3*02:02	NetMHCIIpan	0.04
96	HPV72	E2	WHYVRLEHAMLFKAR	35	49	HLA-DRB3*02:02	NetMHCIIpan	0.04
97	HPV72	E2	CFRYRLQQSVPNLFL	316	330	HLA-DRB3*02:02	NetMHCIIpan	0.04
98	HPV40	E2	HWKYIRYESAIYYTA	32	46	HLA-DRB3*02:02	NetMHCIIpan	0.05
99	HPV40	E2	WKYIRYESAIYYTAR	33	47	HLA-DRB3*02:02	NetMHCIIpan	0.05
100	HPV72	E2	LHWHYVRLEHAMLFK	33	47	HLA-DRB3*02:02	NetMHCIIpan	0.05
101	HPV40	E2	LHWKYIRYESAIYYT	31	45	HLA-DRB3*02:02	NetMHCIIpan	0.06
102	HPV61	E2	HYVRLENAMLFKARQ	36	50	HLA-DRB3*02:02	NetMHCIIpan	0.06
103	HPV72	E2	HYVRLEHAMLFKARQ	36	50	HLA-DRB3*02:02	NetMHCIIpan	0.06
104	HPV72	E2	RYRLQQSVPNLFLKA	318	332	HLA-DRB3*02:02	NetMHCIIpan	0.06
105	HPV81	E2	CLRYRLRSSVPHLFV	310	324	HLA-DRB3*02:02	NetMHCIIpan	0.06
106	HPV81	E2	LRYRLRSSVPHLFVN	311	325	HLA-DRB3*02:02	NetMHCIIpan	0.06
107	HPV40	E2	KYIRYESAIYYTARQ	34	48	HLA-DRB3*02:02	NetMHCIIpan	0.07
108	HPV72	E2	KCFRYRLQQSVPNLF	315	329	HLA-DRB3*02:02	NetMHCIIpan	0.07
109	HPV81	E2	RYRLRSSVPHLFVNA	312	326	HLA-DRB3*02:02	NetMHCIIpan	0.07
110	HPV61	E2	ILHWHYVRLENAMLF	32	46	HLA-DRB3*02:02	NetMHCIIpan	0.08
111	HPV70	E2	YWKYVRLENAIFYAA	37	51	HLA-DRB3*02:02	NetMHCIIpan	0.08
112	HPV72	E2	ILHWHYVRLEHAMLF	32	46	HLA-DRB3*02:02	NetMHCIIpan	0.09
113	HPV70	E2	WKYVRLENAIFYAAR	38	52	HLA-DRB3*02:02	NetMHCIIpan	0.15
114	HPV43	E2	WKYIRYECALYYKAR	33	47	HLA-DRB3*02:02	NetMHCIIpan	0.17
115	HPV70	E2	NYWKYVRLENAIFYA	36	50	HLA-DRB3*02:02	NetMHCIIpan	0.17
116	HPV43	E2	HWKYIRYECALYYKA	32	46	HLA-DRB3*02:02	NetMHCIIpan	0.19
117	HPV81	E2	KCLRYRLRSSVPHLF	309	323	HLA-DRB3*02:02	NetMHCIIpan	0.2
118	HPV81	E2	WHCIRLENAILFKAR	33	47	HLA-DRB3*02:02	NetMHCIIpan	0.23
119	HPV40	E2	ILHWKYIRYESAIYY	30	44	HLA-DRB3*02:02	NetMHCIIpan	0.25
120	HPV72	E2	HWHYVRLEHAMLFKA	34	48	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.25
121	HPV72	E2	LHWHYVRLEHAMLFK	33	47	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.28
122	HPV40	E2	KCFRYRLGKVSHLFC	303	317	HLA-DRB3*02:02	NetMHCIIpan	0.31
123	HPV43	E2	KCFRYRLNKHKHLFA	303	317	HLA-DRB3*02:02	NetMHCIIpan	0.31
124	HPV81	E2	HWHCIRLENAILFKA	32	46	HLA-DRB3*02:02	NetMHCIIpan	0.31
125	HPV40	E2	LKCFRYRLGKVSHLF	302	316	HLA-DRB3*02:02	NetMHCIIpan	0.32
126	HPV72	E2	ILHWHYVRLEHAMLF	32	46	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.35
127	HPV72	E2	WHYVRLEHAMLFKAR	35	49	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.37
128	HPV11	E2	HWKCIRLESVLLHKA	32	46	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.4
129	HPV43	E2	LHWKYIRYECALYYK	31	45	HLA-DRB3*02:02	NetMHCIIpan	0.43
130	HPV43	E2	KYIRYECALYYKARE	34	48	HLA-DRB3*02:02	NetMHCIIpan	0.43
131	HPV11	E2	WKCIRLESVLLHKAK	33	47	HLA-DRB3*02:02	NetMHCIIpan	0.44
132	HPV70	E2	INYWKYVRLENAIFY	35	49	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.49
133	HPV11	E2	WKCIRLESVLLHKAK	33	47	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.51
134	HPV61	E2	LHWHYVRLENAMLFK	33	47	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.53
135	HPV61	E2	HWHYVRLENAMLFKA	34	48	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.53
136	HPV11	E2	MHWKCIRLESVLLHK	31	45	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.54
137	HPV61	E2	ILHWHYVRLENAMLF	32	46	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.61
138	HPV61	E2	WHYVRLENAMLFKAR	35	49	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.64
139	HPV70	E2	QINYWKYVRLENAIF	34	48	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.64
140	HPV70	E2	NYWKYVRLENAIFYA	36	50	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.65
141	HPV72	E2	QILHWHYVRLEHAML	31	45	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.7
142	HPV11	E2	IMHWKCIRLESVLLH	30	44	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.71
143	HPV43	E2	RQKAYLAIELQMSLE	66	80	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.72
144	HPV72	E2	HYVRLEHAMLFKARQ	36	50	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.72
145	HPV70	E2	YWKYVRLENAIFYAA	37	51	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.73
146	HPV43	E2	SRQKAYLAIELQMSL	65	79	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.75
147	HPV43	E2	QKAYLAIELQMSLEA	67	81	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.77
148	HPV42	E2	IEIHLALETLLQSSY	73	87	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.78
149	HPV11	E2	KCIRLESVLLHKAKQ	34	48	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.88
150	HPV43	E2	HWKYIRYECALYYKA	32	46	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.88
151	HPV42	E2	AIEIHLALETLLQSS	72	86	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.93
152	HPV43	E2	LHWKYIRYECALYYK	31	45	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	1
153	HPV43	E2	KAYLAIELQMSLEAL	68	82	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	1