HPVomics

A therapeutic and epitome resource for Human Papillomaviruses

Efficient putative LR-HPVs E5 protein epitopes (MHC-I Binders)

---

S.No.	HPV type	Target region	Peptide seuences	Start	End	Length	Allele	Percentile rank	ann_ic50	smm_ic50
1	HPV6	E5-delta	HTKCKKCNK	42	50	9	HLA-A*30:01	0.2	4.56	6.62
2	HPV6	E5-delta	HYRAVQGDK	33	41	9	HLA-A*30:01	0.3	8.15	14.59
3	HPV6	E5-delta	FIVGMLGLL	22	30	9	HLA-A*02:03	0.75	9.85	30.83
4	HPV6	E5-delta	FIVGMLGLL	22	30	9	HLA-A*02:06	0.75	12.75	32.55
5	HPV6	E5-delta	LLLMHYRAV	29	37	9	HLA-A*02:03	0.8	18.74	25.76
6	HPV6	E5-gamma	FILPVIIAFV	16	25	10	HLA-A*02:06	0.15	6.33	8.22
7	HPV6	E5-gamma	FILPVIIAFV	16	25	10	HLA-A*02:01	0.15	9.49	12.09
8	HPV6	E5-gamma	LLLYLLLWLL	51	60	10	HLA-A*02:01	0.2	24.79	7.12
9	HPV6	E5-gamma	EVVPVQIAA	2	10	9	HLA-A*68:02	0.2	4.47	21.46
10	HPV6	E5-gamma	TTSTFILPV	12	20	9	HLA-A*68:02	0.2	2.96	13.57
11	HPV6	E5-gamma	FIVYTSVLV	40	48	9	HLA-A*02:06	0.25	9.98	11.03
12	HPV6	E5-gamma	IAAGTTSTF	8	16	9	HLA-B*35:01	0.3	7.67	14.88
13	HPV6	E5-gamma	VLVLTLLLYL	46	55	10	HLA-A*02:01	0.3	31.03	24.57
14	HPV6	E5-gamma	IVWISEFIVY	34	43	10	HLA-B*15:01	0.3	33.59	2.25
15	HPV6	E5-gamma	FILPVIIAFV	16	25	10	HLA-A*02:03	0.35	10.86	13.91
16	HPV6	E5-gamma	ILPVIIAFV	17	25	9	HLA-A*02:01	0.4	23.61	18.12
17	HPV6	E5-gamma	LLLYLLLWL	51	59	9	HLA-A*02:01	0.4	19.51	16.07
18	HPV6	E5-gamma	LLYLLLWLL	52	60	9	HLA-A*02:01	0.4	19.57	7.08
19	HPV6	E5-gamma	YLLLWLLLT	54	62	9	HLA-A*02:01	0.4	28.78	20.28
20	HPV6	E5-gamma	ALYIHYYIV	79	87	9	HLA-A*02:01	0.4	29.25	20.42
21	HPV6	E5-gamma	LLVCYCPALY	72	81	10	HLA-B*15:01	0.4	20.3	4.52
22	HPV6	E5-gamma	ALYIHYYIV	79	87	9	HLA-A*02:03	0.4	10.41	6.34
23	HPV6	E5-gamma	CPALYIHYY	77	85	9	HLA-B*35:01	0.4	23.83	16.97
24	HPV6	E5-gamma	FIVYTSVLV	40	48	9	HLA-A*68:02	0.4	13.24	27.45
25	HPV6	E5-gamma	ILPVIIAFV	17	25	9	HLA-A*02:03	0.45	10.27	9.1
26	HPV6	E5-gamma	LLVCYCPAL	72	80	9	HLA-A*02:01	0.5	10.65	25.42
27	HPV6	E5-gamma	IIAFVVCFV	21	29	9	HLA-A*02:03	0.55	19.07	14.09
28	HPV6	E5-gamma	LQFFLLTLL	65	73	9	HLA-A*02:06	0.55	24.1	15.37
29	HPV6	E5-gamma	FILPVIIAF	16	24	9	HLA-B*35:01	0.6	22.95	34.48
30	HPV6	E5-gamma	IIAFVVCFV	21	29	9	HLA-A*68:02	0.6	29.91	17.44
31	HPV6	E5-gamma	FILPVIIAF	16	24	9	HLA-A*02:06	0.6	29.06	18.26
32	HPV6	E5-gamma	FIVYTSVLV	40	48	9	HLA-A*02:03	0.75	21.51	22.49
33	HPV6	E5-gamma	FVVCFVSII	24	32	9	HLA-A*02:03	0.9	18.8	34.67
34	HPV6	E5-gamma	QIAAGTTSTF	7	16	10	HLA-B*15:01	1.2	20.43	28.46
35	HPV11	E5-delta	FLWLFTAFV	16	24	9	HLA-A*02:01	0.1	3.2	0.76
36	HPV11	E5-delta	FLWLFTAFVV	16	25	10	HLA-A*02:01	0.15	7.3	2.36
37	HPV11	E5-delta	MSHGDNGDY	62	70	9	HLA-A*30:02	0.15	19.01	27.38
38	HPV11	E5-delta	WLFLWLFTA	14	22	9	HLA-A*02:01	0.2	11.55	7.54
39	HPV11	E5-delta	FTAFVVAVL	20	28	9	HLA-A*68:02	0.2	4.15	8.95
40	HPV11	E5-delta	WLFTAFVVAV	18	27	10	HLA-A*02:06	0.25	20.8	22.43
41	HPV11	E5-delta	FLWLFTAFV	16	24	9	HLA-A*02:03	0.3	6.6	6.64
42	HPV11	E5-delta	WLFTAFVVAV	18	27	10	HLA-A*02:01	0.35	17.85	30.02
43	HPV11	E5-delta	FLWLFTAFV	16	24	9	HLA-A*02:06	0.35	15.1	4.75
44	HPV11	E5-delta	FVVAVLGLL	23	31	9	HLA-A*02:06	0.4	9.66	20.02
45	HPV11	E5-delta	WLFTAFVVAV	18	27	10	HLA-A*02:03	0.4	15.37	9.08
46	HPV11	E5-delta	FLWLFTAFVV	16	25	10	HLA-A*02:03	0.55	27.84	20.24
47	HPV11	E5-delta	WLFLWLFTA	14	22	9	HLA-A*02:06	0.8	32.71	26.89
48	HPV11	E5-delta	LLLLHYRAV	30	38	9	HLA-A*02:03	0.95	30.55	39.08
49	HPV11	E5-delta	WLFLWLFTAF	14	23	10	HLA-B*15:01	1.25	26.27	28.92
50	HPV11	E5-gamma	FPAFYIHIY	77	85	9	HLA-B*35:01	0.1	3.67	2.37
51	HPV11	E5-gamma	FPAFYIHIY	77	85	9	HLA-B*53:01	0.2	14.32	35.55
52	HPV11	E5-gamma	LLLYLLLWLL	51	60	10	HLA-A*02:01	0.2	24.79	7.12
53	HPV11	E5-gamma	IILISDFVVY	34	43	10	HLA-B*15:01	0.2	12.09	2.6
54	HPV11	E5-gamma	ILISDFVVY	35	43	9	HLA-B*15:01	0.2	10.28	15.07
55	HPV11	E5-gamma	EVVPVQIAA	2	10	9	HLA-A*68:02	0.2	4.47	21.46
56	HPV11	E5-gamma	FVVYTSVLV	40	48	9	HLA-A*68:02	0.2	4.67	10.46
57	HPV11	E5-gamma	FVVYTSVLV	40	48	9	HLA-A*02:06	0.25	6.75	9.03
58	HPV11	E5-gamma	TTTTLILPV	12	20	9	HLA-A*68:02	0.3	4.68	19.35
59	HPV11	E5-gamma	VLVLTLLLYL	46	55	10	HLA-A*02:01	0.3	31.03	24.57
60	HPV11	E5-gamma	LTLCVCYFPA	70	79	10	HLA-A*02:06	0.4	36.78	38.81
61	HPV11	E5-gamma	LLLYLLLWL	51	59	9	HLA-A*02:01	0.4	19.51	16.07
62	HPV11	E5-gamma	LLYLLLWLL	52	60	9	HLA-A*02:01	0.4	19.57	7.08
63	HPV11	E5-gamma	YLLLWLLLT	54	62	9	HLA-A*02:01	0.4	28.78	20.28
64	HPV11	E5-gamma	FAVCILSIV	24	32	9	HLA-A*02:06	0.45	11.63	19.7
65	HPV11	E5-gamma	FAVCILSIV	24	32	9	HLA-A*68:02	0.5	19.31	32.93
66	HPV11	E5-gamma	TLILPVVIAF	15	24	10	HLA-B*15:01	0.75	19.04	14.13
67	HPV11	E5-gamma	FAVCILSIV	24	32	9	HLA-A*02:03	0.75	18.28	25
68	HPV11	E5-gamma	ILPVVIAFA	17	25	9	HLA-A*02:03	0.95	33.36	33.11
69	HPV11	E5-gamma	LIILISDFV	33	41	9	HLA-A*02:06	0.95	38.64	37.12
70	HPV40	E5	MALWMLLAF	13	21	9	HLA-B*35:01	0.1	4.08	2.2
71	HPV40	E5	MALWMLLAF	13	21	9	HLA-B*53:01	0.2	15.28	29.3
72	HPV40	E5	MLLAFITVLL	17	26	10	HLA-A*02:01	0.2	18.88	17.24
73	HPV40	E5	TLYLYRYTK	35	43	9	HLA-A*03:01	0.2	27.46	34.98
74	HPV40	E5	WMLLAFITV	16	24	9	HLA-A*02:06	0.2	9.53	5.1
75	HPV40	E5	RTLYLYRYTK	34	43	10	HLA-A*11:01	0.25	14.79	8.49
76	HPV40	E5	MLLAFITVL	17	25	9	HLA-A*02:01	0.3	7.7	11.35
77	HPV40	E5	RTLYLYRYTK	34	43	10	HLA-A*03:01	0.3	14.6	9.62
78	HPV40	E5	WMALWMLLAF	12	21	10	HLA-B*15:01	0.35	20.38	4.04
79	HPV40	E5	TLYLYRYTK	35	43	9	HLA-A*11:01	0.35	16.46	30.22
80	HPV40	E5	ALWMLLAFI	14	22	9	HLA-A*02:01	0.4	16.2	8
81	HPV40	E5	WMLLAFITV	16	24	9	HLA-A*02:01	0.4	21.61	16.79
82	HPV40	E5	WMALWMLLA	12	20	9	HLA-A*02:03	0.75	15.12	24.32
83	HPV40	E5	LLAFITVLL	18	26	9	HLA-A*02:03	0.8	30.8	28.38
84	HPV40	E5	MLLAFITVL	17	25	9	HLA-A*02:03	1	30.73	39.44
85	HPV43	E5	WMFLWLLVTV	12	21	10	HLA-A*02:06	0.2	20.69	10.69
86	HPV43	E5	WMFLWLLVTV	12	21	10	HLA-A*02:01	0.2	16.84	9.09
87	HPV43	E5	TVITVLILV	20	28	9	HLA-A*68:02	0.2	5.51	10.51
88	HPV43	E5	VLAFHYRTLK	28	37	10	HLA-A*03:01	0.25	11.45	19.06
89	HPV43	E5	CTFEDGDTW	4	12	9	HLA-B*58:01	0.3	14.35	30.08
90	HPV43	E5	WMFLWLLVTV	12	21	10	HLA-A*02:03	0.35	13.32	3.64
91	HPV43	E5	FLWLLVTVI	14	22	9	HLA-A*02:01	0.4	20.6	7.11
92	HPV43	E5	LILVLAFHYR	25	34	10	HLA-A*31:01	0.4	36.23	37.71
93	HPV43	E5	ILVLAFHYR	26	34	9	HLA-A*31:01	0.4	18.86	19.93
94	HPV43	E5	WLLVTVITV	16	24	9	HLA-A*02:01	0.5	32.33	16.87
95	HPV43	E5	TVITVLILV	20	28	9	HLA-A*02:06	0.5	10.61	23.85
96	HPV44	E5-delta	CTFDDGDTW	4	12	9	HLA-B*58:01	0.3	22.03	32.23
97	HPV44	E5-delta	TVQCVTCSK	35	43	9	HLA-A*11:01	0.35	14.75	28.93
98	HPV44	E5-delta	KTVQCVTCSK	34	43	10	HLA-A*11:01	0.35	33.1	31.47
99	HPV44	E5-delta	LLLWLLLTL	13	21	9	HLA-A*02:01	0.4	22.23	15.35
100	HPV44	E5-delta	IIALLLMHLK	25	34	10	HLA-A*03:01	0.45	39.37	39.19
101	HPV44	E5-delta	LLLTLIVTI	17	25	9	HLA-A*02:01	0.5	18.46	29.45
102	HPV44	E5-delta	LLLMHLKTV	28	36	9	HLA-A*02:03	0.6	15.96	16.59
103	HPV44	E5-gamma	LTLCVCFFPA	70	79	10	HLA-A*02:06	0.2	11.61	10.25
104	HPV44	E5-gamma	ILVLTLLLYL	46	55	10	HLA-A*02:01	0.2	23.98	17.56
105	HPV44	E5-gamma	LLLYLLLWLL	51	60	10	HLA-A*02:01	0.2	24.79	7.12
106	HPV44	E5-gamma	FYLLTLCVCF	67	76	10	HLA-A*23:01	0.25	16.29	7.7
107	HPV44	E5-gamma	FIVYTSILV	40	48	9	HLA-A*02:06	0.3	10.57	10.53
108	HPV44	E5-gamma	IICISDFIVY	34	43	10	HLA-B*15:01	0.35	27.55	3.19
109	HPV44	E5-gamma	LLTSALQFYL	60	69	10	HLA-A*02:01	0.4	16.9	35.77
110	HPV44	E5-gamma	SLLPVVIAL	16	24	9	HLA-A*02:01	0.4	12.17	17.91
111	HPV44	E5-gamma	LLLYLLLWL	51	59	9	HLA-A*02:01	0.4	19.51	16.07
112	HPV44	E5-gamma	LLYLLLWLL	52	60	9	HLA-A*02:01	0.4	19.57	7.08
113	HPV44	E5-gamma	YLLLWLLLT	54	62	9	HLA-A*02:01	0.4	28.78	20.28
114	HPV44	E5-gamma	ALFVCFVSIV	23	32	10	HLA-A*02:03	0.4	18.53	5.89
115	HPV44	E5-gamma	LLWLLLTSA	56	64	9	HLA-A*02:01	0.5	34.3	27.17
116	HPV44	E5-gamma	FIVYTSILV	40	48	9	HLA-A*68:02	0.5	16.19	37.2
117	HPV44	E5-gamma	FIVYTSILV	40	48	9	HLA-A*02:03	0.75	25.9	23.01
118	HPV54	E5	FLVAFILLWV	29	38	10	HLA-A*02:06	0.15	19.84	6.95
119	HPV54	E5	FLVAFILLWV	29	38	10	HLA-A*02:01	0.15	9.01	3.08
120	HPV54	E5	ITTAFTFFLV	22	31	10	HLA-A*68:02	0.15	9.44	14.46
121	HPV54	E5	FLVAFILLWV	29	38	10	HLA-A*02:03	0.15	6.1	3.56
122	HPV54	E5	LLWVPALCVY	35	44	10	HLA-B*15:01	0.2	10.52	1.83
123	HPV54	E5	TTAFTFFLV	23	31	9	HLA-A*68:02	0.2	2.39	1.15
124	HPV54	E5	FTFFLVAFI	26	34	9	HLA-A*68:02	0.2	2.79	5.67
125	HPV54	E5	YTVSWLTCW	3	11	9	HLA-B*58:01	0.2	4.56	12.57
126	HPV54	E5	WQCITTAFTF	19	28	10	HLA-B*15:01	0.3	12.77	3.73
127	HPV54	E5	FFLVAFILLW	28	37	10	HLA-A*23:01	0.35	35.97	32.04
128	HPV54	E5	TTAFTFFLV	23	31	9	HLA-A*02:06	0.35	10.1	17.81
129	HPV54	E5	FILLWVPAL	33	41	9	HLA-A*02:01	0.4	7.1	16.26
130	HPV54	E5	WVPALCVYV	37	45	9	HLA-A*68:02	0.4	4.4	26.28
131	HPV54	E5	LLWQCITTA	17	25	9	HLA-A*02:01	0.5	22.48	23.13
132	HPV54	E5	ITTAFTFFL	22	30	9	HLA-A*68:02	0.5	9.83	31.81
133	HPV54	E5	WVPALCVYV	37	45	9	HLA-A*02:06	0.5	11.22	24.52
134	HPV54	E5	MLYTVSWLT	1	9	9	HLA-A*02:01	0.6	10.66	34.52
135	HPV54	E5	LVAFILLWV	30	38	9	HLA-A*68:02	0.6	24.75	32.4
136	HPV54	E5	FTFFLVAFIL	26	35	10	HLA-A*68:02	0.6	15.76	35.92
137	HPV54	E5	FILLWVPAL	33	41	9	HLA-A*02:06	0.65	15.33	23.69
138	HPV54	E5	LVAFILLWV	30	38	9	HLA-A*02:03	0.7	28.27	20.46
139	HPV54	E5	LLWQCITTAF	17	26	10	HLA-B*15:01	0.7	13.02	12.8
140	HPV61	E5	FLLLLLIAI	28	36	9	HLA-A*02:01	0.2	13.43	6.62
141	HPV61	E5	LLIAILLYRL	32	41	10	HLA-A*02:01	0.35	25.17	32.62
142	HPV61	E5	FLFLLLLLI	26	34	9	HLA-A*02:01	0.4	18.22	5.48
143	HPV61	E5	LLIAILLYR	32	40	9	HLA-A*31:01	0.5	31.83	25.97
144	HPV61	E5	FLLLLLIAI	28	36	9	HLA-A*02:06	0.55	33.04	11.03
145	HPV61	E5	QQNCGLLFL	19	27	9	HLA-A*02:06	0.75	14.35	31.01
146	HPV61	E5	QQNCGLLFLF	19	28	10	HLA-B*15:01	1	15.23	22.04
147	HPV70	E5	VYISMIALVF	4	13	10	HLA-A*23:01	0.1	5.15	0.76
148	HPV70	E5	AYMWLLLFVF	37	46	10	HLA-A*24:02	0.1	12.24	4.32
149	HPV70	E5	LQMFCIYLLF	54	63	10	HLA-B*15:01	0.15	9.11	2.07
150	HPV70	E5	VYISMIALVF	4	13	10	HLA-A*24:02	0.15	11.76	7.12
151	HPV70	E5	FILPMWFLHI	64	73	10	HLA-A*02:06	0.2	5.87	22.08
152	HPV70	E5	AYMWLLLFVF	37	46	10	HLA-A*23:01	0.2	9.32	2.73
153	HPV70	E5	YMWLLLFVFI	38	47	10	HLA-A*02:01	0.2	7.95	18.51
154	HPV70	E5	MYIVYISMI	1	9	9	HLA-A*23:01	0.2	12.64	25.14
155	HPV70	E5	MFCIYLLFF	56	64	9	HLA-A*23:01	0.2	22.86	18.81
156	HPV70	E5	SMIALVFLV	7	15	9	HLA-A*02:01	0.2	3.29	2.57
157	HPV70	E5	YLLFFILPM	60	68	9	HLA-A*02:01	0.2	7.02	8
158	HPV70	E5	LPSVHLCAY	30	38	9	HLA-B*35:01	0.2	3.53	4.77
159	HPV70	E5	TPLQMFCIY	52	60	9	HLA-B*35:01	0.2	6.46	18.47
160	HPV70	E5	MIALVFLVW	8	16	9	HLA-B*58:01	0.2	7.96	13.31
161	HPV70	E5	SMIALVFLV	7	15	9	HLA-A*02:06	0.2	6.62	7.74
162	HPV70	E5	LVFLVWFAV	11	19	9	HLA-A*02:06	0.25	10.81	6.48
163	HPV70	E5	LQMFCIYLL	54	62	9	HLA-A*02:06	0.25	9.3	8.48
164	HPV70	E5	LVFLVWFAV	11	19	9	HLA-A*68:02	0.3	18.55	19.04
165	HPV70	E5	QMFCIYLLF	55	63	9	HLA-A*32:01	0.3	25.23	23.71
166	HPV70	E5	ISMIALVFLV	6	15	10	HLA-A*02:01	0.3	10.54	26.58
167	HPV70	E5	LLPSVHLCAY	29	38	10	HLA-B*15:01	0.3	32.67	1.91
168	HPV70	E5	QMFCIYLLFF	55	64	10	HLA-A*23:01	0.35	19.73	34.18
169	HPV70	E5	ALVFLVWFAV	10	19	10	HLA-A*02:01	0.35	24.84	33.46
170	HPV70	E5	FLVWFAVCL	13	21	9	HLA-A*02:01	0.4	27.99	17.42
171	HPV70	E5	HLCAYMWLL	34	42	9	HLA-A*02:01	0.4	12.96	19.91
172	HPV70	E5	WLLLFVFIV	40	48	9	HLA-A*02:01	0.4	21.93	4.58
173	HPV70	E5	LQMFCIYLL	54	62	9	HLA-A*02:01	0.4	19.6	17.66
174	HPV70	E5	SMIALVFLV	7	15	9	HLA-A*02:03	0.45	14.8	4.81
175	HPV70	E5	ALVFLVWFA	10	18	9	HLA-A*02:01	0.5	23.66	22.7
176	HPV70	E5	FLHILSVYA	70	78	9	HLA-A*02:03	0.55	16.97	14.65
177	HPV70	E5	FIVVHTTPL	46	54	9	HLA-A*02:06	0.55	8.33	30.87
178	HPV70	E5	IVYISMIALV	3	12	10	HLA-A*02:03	0.65	20.07	24.9
179	HPV70	E5	FIVVHTTPL	46	54	9	HLA-A*02:03	0.65	6.11	30.62
180	HPV70	E5	QMFCIYLLFF	55	64	10	HLA-B*15:01	0.85	30.57	15.75
181	HPV70	E5	CSVPLLPSV	25	33	9	HLA-A*02:06	0.9	14.54	38.77
182	HPV72	E5	FLCMLIIIVV	27	36	10	HLA-A*02:01	0.2	15.93	5.51
183	HPV72	E5	FLCMLIIIV	27	35	9	HLA-A*02:01	0.2	27.85	5.92
184	HPV72	E5	IIIVVLLYR	32	40	9	HLA-A*68:01	0.35	17.88	26.7
185	HPV72	E5	LIIIVVLLYR	31	40	10	HLA-A*68:01	0.4	39.36	4.61
186	HPV72	E5	GLWFFLCML	23	31	9	HLA-A*02:01	0.5	32.77	16.83
187	HPV72	E5	IIIVVLLYR	32	40	9	HLA-A*31:01	0.55	39.64	29.96
188	HPV81	E5	FLLCIILALI	27	36	10	HLA-A*02:01	0.2	14.23	5.62
189	HPV81	E5	FLLCIILAL	27	35	9	HLA-A*02:01	0.2	4.83	3.72
190	HPV81	E5	ALILFVVYK	34	42	9	HLA-A*11:01	0.2	10.32	16.04
191	HPV81	E5	LALILFVVY	33	41	9	HLA-B*35:01	0.2	18.16	21.36
192	HPV81	E5	ILALILFVVY	32	41	10	HLA-B*15:01	0.3	32.97	1.41
193	HPV81	E5	IILALILFV	31	39	9	HLA-A*02:01	0.4	10.44	18.75
194	HPV81	E5	ILALILFVV	32	40	9	HLA-A*02:01	0.4	16.13	6.4
195	HPV81	E5	ILALILFVV	32	40	9	HLA-A*02:03	0.5	28.66	9.25
196	HPV81	E5	FLLCIILAL	27	35	9	HLA-A*02:06	0.5	21.98	8.21
197	HPV81	E5	IILALILFV	31	39	9	HLA-A*02:06	0.5	19.6	9.63
198	HPV81	E5	FLLCIILALI	27	36	10	HLA-A*02:03	0.6	36.95	15.68
199	HPV81	E5	FLLCIILAL	27	35	9	HLA-A*02:03	0.65	32.95	15.99