HPVomics

Efficient putative LR-HPVs E6 protein epitopes (MHC-I Binders)

S.No.	HPV type	Target region	Peptide seuences	Start	End	Length	Allele	Percentile rank	ann_ic50	smm_ic50
1	HPV6	E6	KVKHILTKAR	116	125	10	HLA-A*31:01	0.15	9.18	20.11
2	HPV6	E6	YLCHKPLCEV	105	114	10	HLA-A*02:03	0.2	7.79	12.4
3	HPV6	E6	AYKHLKVLFR	47	56	10	HLA-A*31:01	0.2	10.94	15.08
4	HPV6	E6	TTAEIYSYA	39	47	9	HLA-A*68:02	0.2	2.21	6.32
5	HPV6	E6	TAEIYSYAY	40	48	9	HLA-B*35:01	0.2	10.01	14.68
6	HPV6	E6	YLCHKPLCEV	105	114	10	HLA-A*02:01	0.25	26.55	20.63
7	HPV6	E6	NQYRHFDYA	75	83	9	HLA-A*02:06	0.3	8.84	14.78
8	HPV6	E6	YSYAYKHLK	44	52	9	HLA-A*11:01	0.3	13.19	21.99
9	HPV6	E6	RFIKLNCTW	125	133	9	HLA-B*58:01	0.3	24.29	28.73
10	HPV6	E6	LFRGGYPYA	54	62	9	HLA-A*30:01	0.3	7.94	17.26
11	HPV6	E6	LIRCYLCHK	101	109	9	HLA-A*30:01	0.3	9.18	14.39
12	HPV6	E6	KLNCTWKGR	128	136	9	HLA-A*31:01	0.4	7.27	28.61
13	HPV6	E6	YSYAYKHLK	44	52	9	HLA-A*68:01	0.45	13.62	35.6
14	HPV6	E6	VLIRCYLCHK	100	109	10	HLA-A*03:01	0.45	31.58	38.92
15	HPV6	E6	KVLFRGGYPY	52	61	10	HLA-B*15:01	0.8	33.26	15.32
16	HPV11	E6	TTAEIYAYA	39	47	9	HLA-A*68:02	0.2	1.82	4.43
17	HPV11	E6	NQYRHFNYA	75	83	9	HLA-A*02:06	0.3	7.82	12.81
18	HPV11	E6	AYKNLKVVWR	47	56	10	HLA-A*31:01	0.3	12.46	31.8
19	HPV11	E6	TAEIYAYAY	40	48	9	HLA-B*35:01	0.3	14.35	24.41
20	HPV11	E6	LIRCYLCHK	101	109	9	HLA-A*30:01	0.3	9.18	14.39
21	HPV11	E6	KLKHILGKAR	116	125	10	HLA-A*31:01	0.35	37.14	30.93
22	HPV11	E6	KLNNQWKGR	128	136	9	HLA-A*31:01	0.35	10.41	26.7
23	HPV11	E6	YAYAYKNLK	44	52	9	HLA-A*68:01	0.4	12.46	36.02
24	HPV11	E6	VLIRCYLCHK	100	109	10	HLA-A*03:01	0.45	31.58	38.92
25	HPV11	E6	ETNEDILKV	92	100	9	HLA-A*68:02	0.6	30.17	38.87
26	HPV11	E6	KLKHILGKA	116	124	9	HLA-A*02:03	0.8	8.62	32.96
27	HPV40	E6	VEEETGLTIL	88	97	10	HLA-B*40:01	0.15	15.46	37.16
28	HPV40	E6	KVNQYRNFR	72	80	9	HLA-A*31:01	0.15	3.31	3.01
29	HPV40	E6	EEETGLTIL	89	97	9	HLA-B*40:01	0.2	17.49	35.88
30	HPV40	E6	CVFCKTVLK	30	38	9	HLA-A*03:01	0.2	37.07	31.46
31	HPV40	E6	RIRCCKCHK	100	108	9	HLA-A*30:01	0.2	3.63	4.46
32	HPV40	E6	CVFCKTVLK	30	38	9	HLA-A*11:01	0.25	19.11	16.68
33	HPV40	E6	AFRELYVVWR	46	55	10	HLA-A*31:01	0.3	16.51	31.51
34	HPV40	E6	IVKKTQFFK	119	127	9	HLA-A*30:01	0.3	7.76	13.52
35	HPV40	E6	CVFCKTVLK	30	38	9	HLA-A*68:01	0.35	14.98	24.63
36	HPV40	E6	IVKKTQFFK	119	127	9	HLA-A*11:01	0.35	29.39	35.34
37	HPV40	E6	KTAEVLAFA	38	46	9	HLA-A*02:06	0.4	6.04	21.06
38	HPV40	E6	SQARTLYEL	7	15	9	HLA-A*02:06	0.55	10.06	29.41
39	HPV40	E6	FAFRELYVV	45	53	9	HLA-A*02:06	0.55	9.26	31.66
40	HPV40	E6	VLKTAEVLAF	36	45	10	HLA-B*15:01	0.6	15.56	10.55
41	HPV42	E6	KICALRHYER	73	82	10	HLA-A*31:01	0.15	6.15	8.27
42	HPV42	E6	EFNSKICALR	69	78	10	HLA-A*33:01	0.15	8.74	29.14
43	HPV42	E6	LEFNSKICAL	68	77	10	HLA-B*40:01	0.2	27.3	35.16
44	HPV42	E6	FNSKICALR	70	78	9	HLA-A*68:01	0.2	10.57	14.64
45	HPV42	E6	SAFWYTVEK	83	91	9	HLA-A*68:01	0.2	5.79	17.56
46	HPV42	E6	SAFWYTVEK	83	91	9	HLA-A*11:01	0.2	6.92	15.29
47	HPV42	E6	RSAFWYTVEK	82	91	10	HLA-A*11:01	0.2	12.34	20.74
48	HPV42	E6	YQLCKEFGL	14	22	9	HLA-A*02:06	0.25	4.63	8.6
49	HPV42	E6	FNSKICALR	70	78	9	HLA-A*33:01	0.3	26.18	32.96
50	HPV42	E6	RSAFWYTVEK	82	91	10	HLA-A*03:01	0.3	19.61	17.47
51	HPV42	E6	ALRHYERSAF	76	85	10	HLA-B*15:01	1.2	38.94	27.88
52	HPV43	E6	LSFAFRDLK	44	52	9	HLA-A*11:01	0.2	10.14	15.64
53	HPV43	E6	TTEVLSFAFR	40	49	10	HLA-A*68:01	0.2	8.23	17.91
54	HPV43	E6	AQFFKIHSV	124	132	9	HLA-A*02:06	0.25	11.7	6.74
55	HPV43	E6	IVQKAQFFK	120	128	9	HLA-A*11:01	0.25	12.25	16.19
56	HPV43	E6	AFRDLKVVWR	47	56	10	HLA-A*31:01	0.3	20.06	21.55
57	HPV43	E6	SQYRHFDYA	75	83	9	HLA-A*02:06	0.35	6.49	15.8
58	HPV43	E6	LQFHGKISQY	68	77	10	HLA-B*15:01	0.35	11.83	4.95
59	HPV43	E6	SQYRHFDYAA	75	84	10	HLA-A*02:06	0.4	21.88	39.62
60	HPV43	E6	LSFAFRDLK	44	52	9	HLA-A*68:01	0.5	15.79	36.02
61	HPV43	E6	MTARSCSQNA	1	10	10	HLA-A*68:02	0.55	31.05	31.28
62	HPV43	E6	VWRDGYPFA	54	62	9	HLA-A*30:01	0.6	27.79	37.24
63	HPV43	E6	AQFFKIHSV	124	132	9	HLA-A*02:03	0.65	9.04	22.85
64	HPV44	E6	AYKQLYVVYR	47	56	10	HLA-A*31:01	0.2	9.04	31.07
65	HPV44	E6	VYRGNFPFA	54	62	9	HLA-A*30:01	0.2	6.67	24.66
66	HPV44	E6	YLCHKPLCHV	105	114	10	HLA-A*02:03	0.25	7.39	14.56
67	HPV44	E6	KVRHILDKAR	116	125	10	HLA-A*31:01	0.25	19.5	18.64
68	HPV44	E6	NQFRHFNYA	75	83	9	HLA-A*02:06	0.3	6.89	14.14
69	HPV44	E6	STAEVYSFA	39	47	9	HLA-A*68:02	0.3	3.49	21.51
70	HPV44	E6	RFIKLQDTW	125	133	9	HLA-B*58:01	0.3	16.74	34.78
71	HPV44	E6	TAEVYSFAY	40	48	9	HLA-B*35:01	0.3	11.01	12.35
72	HPV44	E6	LIRCYLCHK	101	109	9	HLA-A*30:01	0.3	9.18	14.39
73	HPV44	E6	YSFAYKQLYV	44	53	10	HLA-A*02:01	0.3	38.67	28.81
74	HPV44	E6	YSFAYKQLYV	44	53	10	HLA-A*68:02	0.4	36.94	21.69
75	HPV44	E6	VLIRCYLCHK	100	109	10	HLA-A*03:01	0.45	31.58	38.92
76	HPV44	E6	KVRHILDKA	116	124	9	HLA-A*30:01	0.5	14.04	25.82
77	HPV44	E6	FAYKQLYVV	46	54	9	HLA-A*02:06	0.6	9.99	32.48
78	HPV54	E6	FQYKDLFVV	77	85	9	HLA-A*02:06	0.1	2.14	0.61
79	HPV54	E6	DYNRRFHCVR	152	161	10	HLA-A*33:01	0.15	11.42	7.09
80	HPV54	E6	KQRHVDYNR	147	155	9	HLA-A*31:01	0.15	6.51	7.29
81	HPV54	E6	QYKDLFVVWR	78	87	10	HLA-A*33:01	0.2	26.91	31.22
82	HPV54	E6	KGRCLHCWK	165	173	9	HLA-A*30:01	0.2	3.17	4.91
83	HPV54	E6	FQYKDLFVV	77	85	9	HLA-A*02:01	0.3	5.32	9.55
84	HPV54	E6	IYAFQYKDLF	74	83	10	HLA-A*23:01	0.35	13.06	35.05
85	HPV54	E6	HIKAVVENSY	18	27	10	HLA-B*15:01	0.35	33.55	3.63
86	HPV54	E6	ETVEQECGK	118	126	9	HLA-A*68:01	0.45	31.16	26.64
87	HPV54	E6	FQYKDLFVV	77	85	9	HLA-A*02:03	0.55	8.18	19.23
88	HPV54	E6	ELHGQINYR	100	108	9	HLA-A*68:01	0.6	29.24	38.15
89	HPV54	E6	GQINYRRHR	103	111	9	HLA-A*31:01	0.6	18.68	36.6
90	HPV54	E6	RTLADLCKV	42	50	9	HLA-A*02:06	0.85	23.7	34.16
91	HPV61	E6	FLLCKDYEV	10	18	9	HLA-A*02:06	0.15	3.82	4.46
92	HPV61	E6	TEELLAFAL	36	44	9	HLA-B*40:01	0.15	5.13	16.25
93	HPV61	E6	FLLCKDYEV	10	18	9	HLA-A*02:01	0.2	3.12	2.51
94	HPV61	E6	LSIVWRHNW	47	55	9	HLA-B*57:01	0.2	11.86	26.9
95	HPV61	E6	IVWRHNWPF	49	57	9	HLA-A*32:01	0.2	3.57	14.96
96	HPV61	E6	LSIVWRHNW	47	55	9	HLA-B*58:01	0.2	4.51	5.81
97	HPV61	E6	RSLAELYIR	91	99	9	HLA-A*31:01	0.35	15.85	12.6
98	HPV61	E6	YIRCHACSK	97	105	9	HLA-A*30:01	0.4	10.77	21.33
99	HPV61	E6	FLLCKDYEV	10	18	9	HLA-A*02:03	0.55	8.21	18.03
100	HPV61	E6	LLAFALKEL	39	47	9	HLA-A*02:03	0.8	9.59	34.51
101	HPV70	E6	RRFHQIAGSY	125	134	10	HLA-A*30:02	0.1	27.97	28.34
102	HPV70	E6	FPNPAERPY	4	12	9	HLA-B*35:01	0.1	2.82	1.22
103	HPV70	E6	FAFSDLFIVY	47	56	10	HLA-B*35:01	0.15	13.19	35.15
104	HPV70	E6	LESITNTKL	90	98	9	HLA-B*40:01	0.15	13.71	36.22
105	HPV70	E6	VYEFAFSDLF	44	53	10	HLA-A*24:02	0.15	25.23	36.45
106	HPV70	E6	LQQTEVYEF	39	47	9	HLA-B*15:01	0.2	33.95	33.11
107	HPV70	E6	SIRCMSCLK	102	110	9	HLA-A*30:01	0.2	3.2	6.29
108	HPV70	E6	NTKRRFHQI	122	130	9	HLA-B*08:01	0.2	10.65	27.83
109	HPV70	E6	VYEFAFSDLF	44	53	10	HLA-A*23:01	0.25	11.28	16.47
110	HPV70	E6	FAFSDLFIV	47	55	9	HLA-A*02:06	0.25	3.44	8.84
111	HPV70	E6	AFSDLFIVYR	48	57	10	HLA-A*31:01	0.25	14.06	14.04
112	HPV70	E6	KFHAKVRELR	70	79	10	HLA-A*31:01	0.25	18.01	8.98
113	HPV70	E6	ITIDCVYCK	28	36	9	HLA-A*11:01	0.25	9.62	24.06
114	HPV70	E6	MARFPNPAER	1	10	10	HLA-A*68:01	0.25	9.96	23.5
115	HPV70	E6	KLRHVNTKR	117	125	9	HLA-A*31:01	0.3	7.26	22.05
116	HPV70	E6	ITIDCVYCK	28	36	9	HLA-A*68:01	0.35	16.55	22.88
117	HPV70	E6	TTLESITNTK	88	97	10	HLA-A*11:01	0.35	34.38	31.98
118	HPV70	E6	FAFSDLFIV	47	55	9	HLA-A*02:01	0.4	9.74	20.47
119	HPV70	E6	LSIRCMSCLK	101	110	10	HLA-A*11:01	0.4	37.61	37.48
120	HPV70	E6	KVRELRHYS	74	82	9	HLA-A*30:01	0.4	5.64	23.66
121	HPV70	E6	FSDLFIVYR	49	57	9	HLA-A*68:01	0.5	16.71	32.47
122	HPV70	E6	TTLESITNTK	88	97	10	HLA-A*68:01	0.6	28.48	39.72
123	HPV70	E6	FAFSDLFIVY	47	56	10	HLA-B*15:01	0.95	27.73	18.04
124	HPV72	E6	YQVQTGIHF	116	124	9	HLA-B*15:01	0.1	4.29	9.66
125	HPV72	E6	TEELLAIAI	38	46	9	HLA-B*40:01	0.15	14.38	35.47
126	HPV72	E6	IVWRDNWPF	51	59	9	HLA-A*32:01	0.3	11.33	23.01
127	HPV72	E6	MPMGLHNPT	1	9	9	HLA-B*35:01	0.3	13.28	37.2
128	HPV72	E6	WTYSGYGPTV	78	87	10	HLA-A*68:02	0.35	11.55	23.3
129	HPV72	E6	RATKVRELR	68	76	9	HLA-A*31:01	0.35	20.8	10.53
130	HPV72	E6	WLLCKEIEV	12	20	9	HLA-A*02:01	0.4	9.2	22.6
131	HPV72	E6	KSLAELYIR	93	101	9	HLA-A*31:01	0.4	21.1	17.12
132	HPV72	E6	YIRCHACCK	99	107	9	HLA-A*30:01	0.5	13.77	30.27
133	HPV72	E6	WLLCKEIEV	12	20	9	HLA-A*02:06	1	20.06	39.68
134	HPV81	E6	WQYSCFGPTV	84	93	10	HLA-A*02:06	0.1	4.05	5.91
135	HPV81	E6	KELTVGELL	40	48	9	HLA-B*40:01	0.15	8.21	32.5
136	HPV81	E6	FLLCKECEV	18	26	9	HLA-A*02:01	0.2	4.71	8.02
137	HPV81	E6	KIAGEWMGK	132	140	9	HLA-A*03:01	0.2	35.88	39.25
138	HPV81	E6	FLLCKECEV	18	26	9	HLA-A*02:06	0.25	6.53	10.68
139	HPV81	E6	LVWRKNWPF	57	65	9	HLA-A*32:01	0.3	5.91	34.35
140	HPV81	E6	YIRCHACYK	105	113	9	HLA-A*30:01	0.3	5.37	14.65
141	HPV81	E6	FAIRELNLV	50	58	9	HLA-A*02:06	0.4	7.13	20.35
142	HPV81	E6	MVSTAVMSL	1	9	9	HLA-A*68:02	0.5	8.5	36.69
143	HPV81	E6	HACYKPLTY	109	117	9	HLA-B*35:01	0.6	25.54	31.23
144	HPV81	E6	WQYSCFGPT	84	92	9	HLA-A*02:06	0.7	8.44	39.04
145	HPV81	E6	FLLCKECEV	18	26	9	HLA-A*02:03	0.75	14.42	21.57
146	HPV81	E6	YLVTGLIHF	122	130	9	HLA-A*02:06	0.85	23.82	35.2
147	HPV81	E6	WQYSCFGPTV	84	93	10	HLA-A*02:03	0.85	19.9	38.04