A therapeutic and epitome resource for Human Papillomaviruses
Efficient putative LR-HPVs E7 protein epitopes (MHC-I Binders)
S.No. |
HPV type |
Target region |
Peptide seuences |
Start |
End |
Length |
Allele |
Percentile rank |
ann_ic50 |
smm_ic50 |
1 |
HPV6 |
E7 |
GTLNIVCPI |
85 |
93 |
9 |
HLA-A*32:01 |
0.3 |
9.59 |
26.24 |
2 |
HPV6 |
E7 |
IVCPICAPK |
89 |
97 |
9 |
HLA-A*11:01 |
0.35 |
21.42 |
33.37 |
3 |
HPV6 |
E7 |
NIVCPICAPK |
88 |
97 |
10 |
HLA-A*68:01 |
0.4 |
30.47 |
15.38 |
4 |
HPV6 |
E7 |
LLLGTLNIV |
82 |
90 |
9 |
HLA-A*02:01 |
0.6 |
25.78 |
30.77 |
5 |
HPV6 |
E7 |
LLLGTLNIV |
82 |
90 |
9 |
HLA-A*02:03 |
0.7 |
11.96 |
24.54 |
6 |
HPV6 |
E7 |
LLLGTLNIV |
82 |
90 |
9 |
HLA-A*02:06 |
0.75 |
14.78 |
31.44 |
7 |
HPV6 |
E7 |
GLHCYEQLV |
22 |
30 |
9 |
HLA-A*02:03 |
0.85 |
24.83 |
29.71 |
8 |
HPV11 |
E7 |
GTLNIVCPI |
85 |
93 |
9 |
HLA-A*32:01 |
0.3 |
9.59 |
26.24 |
9 |
HPV11 |
E7 |
IVCPICAPK |
89 |
97 |
9 |
HLA-A*11:01 |
0.35 |
21.42 |
33.37 |
10 |
HPV11 |
E7 |
NIVCPICAPK |
88 |
97 |
10 |
HLA-A*68:01 |
0.4 |
30.47 |
15.38 |
11 |
HPV11 |
E7 |
LLLGTLNIV |
82 |
90 |
9 |
HLA-A*02:01 |
0.6 |
25.78 |
30.77 |
12 |
HPV11 |
E7 |
LLLGTLNIV |
82 |
90 |
9 |
HLA-A*02:03 |
0.7 |
11.96 |
24.54 |
13 |
HPV11 |
E7 |
LLLGTLNIV |
82 |
90 |
9 |
HLA-A*02:06 |
0.75 |
14.78 |
31.44 |
14 |
HPV40 |
E7 |
LLMGTLHIV |
95 |
103 |
9 |
HLA-A*02:01 |
0.2 |
5.5 |
6.1 |
15 |
HPV40 |
E7 |
LLMGTLHIV |
95 |
103 |
9 |
HLA-A*02:03 |
0.2 |
2.69 |
2.53 |
16 |
HPV40 |
E7 |
RPTLGDIVL |
5 |
13 |
9 |
HLA-B*07:02 |
0.2 |
21.2 |
24.6 |
17 |
HPV40 |
E7 |
LLMGTLHIV |
95 |
103 |
9 |
HLA-A*02:06 |
0.25 |
9.11 |
9.5 |
18 |
HPV40 |
E7 |
QLLMGTLHIV |
94 |
103 |
10 |
HLA-A*02:01 |
0.4 |
24.18 |
34.31 |
19 |
HPV40 |
E7 |
VLNLHPEPV |
12 |
20 |
9 |
HLA-A*02:03 |
0.4 |
7.56 |
9.86 |
20 |
HPV40 |
E7 |
CVFCQCLVR |
71 |
79 |
9 |
HLA-A*68:01 |
0.45 |
35.3 |
22.83 |
21 |
HPV40 |
E7 |
QLLMGTLHIV |
94 |
103 |
10 |
HLA-A*02:03 |
0.5 |
10.81 |
26.32 |
22 |
HPV42 |
E7 |
MLLGTLDIV |
77 |
85 |
9 |
HLA-A*02:06 |
0.4 |
6.8 |
18.77 |
23 |
HPV42 |
E7 |
MLLGTLDIV |
77 |
85 |
9 |
HLA-A*02:01 |
0.4 |
14.38 |
18.88 |
24 |
HPV42 |
E7 |
MLLGTLDIV |
77 |
85 |
9 |
HLA-A*02:03 |
0.75 |
11.6 |
25.52 |
25 |
HPV43 |
E7 |
CTSCLCVIR |
58 |
66 |
9 |
HLA-A*68:01 |
0.3 |
14.01 |
23.91 |
26 |
HPV44 |
E7 |
LQLEPPDPV |
13 |
21 |
9 |
HLA-A*02:06 |
0.25 |
6.29 |
8.62 |
27 |
HPV44 |
E7 |
GSLDILCPV |
84 |
92 |
9 |
HLA-A*02:06 |
0.35 |
4.48 |
16.16 |
28 |
HPV54 |
E7 |
NVATIEDIV |
4 |
12 |
9 |
HLA-A*68:02 |
0.4 |
14.01 |
22.37 |
29 |
HPV54 |
E7 |
LLHQDALQIV |
78 |
87 |
10 |
HLA-A*02:03 |
0.5 |
11.88 |
22.5 |
30 |
HPV54 |
E7 |
ETAVTQPDK |
36 |
44 |
9 |
HLA-A*68:01 |
0.6 |
23.16 |
32.32 |
31 |
HPV61 |
E7 |
LLLGDLSIV |
82 |
90 |
9 |
HLA-A*02:03 |
0.35 |
6.65 |
12.36 |
32 |
HPV61 |
E7 |
LLLGDLSIV |
82 |
90 |
9 |
HLA-A*02:01 |
0.5 |
15.91 |
21.93 |
33 |
HPV61 |
E7 |
TIKDIVLEER |
7 |
16 |
10 |
HLA-A*68:01 |
0.5 |
28.44 |
29.17 |
34 |
HPV61 |
E7 |
QVATIKDIV |
4 |
12 |
9 |
HLA-A*68:02 |
0.5 |
13.7 |
34.09 |
35 |
HPV61 |
E7 |
LLLGDLSIV |
82 |
90 |
9 |
HLA-A*02:06 |
0.55 |
11.13 |
28.09 |
36 |
HPV61 |
E7 |
IVLEERPEV |
11 |
19 |
9 |
HLA-A*02:06 |
0.7 |
18.69 |
22.68 |
37 |
HPV61 |
E7 |
LVEQAQQAY |
44 |
52 |
9 |
HLA-B*35:01 |
0.7 |
14.41 |
38.42 |
38 |
HPV70 |
E7 |
LQLFMETLSF |
90 |
99 |
10 |
HLA-B*15:01 |
0.1 |
3.8 |
0.22 |
39 |
HPV70 |
E7 |
METLSFVCPW |
94 |
103 |
10 |
HLA-B*44:03 |
0.15 |
14.26 |
23.39 |
40 |
HPV70 |
E7 |
QLFMETLSFV |
91 |
100 |
10 |
HLA-A*02:03 |
0.15 |
3.55 |
4.3 |
41 |
HPV70 |
E7 |
QLFMETLSFV |
91 |
100 |
10 |
HLA-A*02:01 |
0.2 |
11.1 |
8.9 |
42 |
HPV70 |
E7 |
RPTLQEIVL |
5 |
13 |
9 |
HLA-B*07:02 |
0.3 |
30.77 |
38.18 |
43 |
HPV70 |
E7 |
LFMETLSFV |
92 |
100 |
9 |
HLA-A*02:06 |
0.55 |
22.75 |
12.18 |
44 |
HPV72 |
E7 |
DNLSIVCPR |
90 |
98 |
9 |
HLA-A*33:01 |
0.25 |
19.06 |
22.7 |
45 |
HPV72 |
E7 |
LLLDNLSIV |
87 |
95 |
9 |
HLA-A*02:03 |
0.25 |
3.5 |
7.06 |
46 |
HPV72 |
E7 |
VTTCGRCYR |
60 |
68 |
9 |
HLA-A*31:01 |
0.25 |
9.8 |
18.68 |
47 |
HPV72 |
E7 |
LLLDNLSIV |
87 |
95 |
9 |
HLA-A*02:01 |
0.3 |
6.75 |
13.25 |
48 |
HPV72 |
E7 |
LLLDNLSIV |
87 |
95 |
9 |
HLA-A*02:06 |
0.35 |
7.31 |
17.97 |
49 |
HPV72 |
E7 |
VTTCGRCYR |
60 |
68 |
9 |
HLA-A*68:01 |
0.4 |
17.62 |
27.57 |
50 |
HPV72 |
E7 |
VVTTCGRCYR |
59 |
68 |
10 |
HLA-A*31:01 |
0.4 |
37.58 |
34.95 |
51 |
HPV72 |
E7 |
QVATIKDIV |
4 |
12 |
9 |
HLA-A*68:02 |
0.5 |
13.7 |
34.09 |
52 |
HPV72 |
E7 |
LVEQAQQAY |
49 |
57 |
9 |
HLA-B*35:01 |
0.7 |
14.41 |
38.42 |
53 |
HPV72 |
E7 |
QLLLDNLSIV |
86 |
95 |
10 |
HLA-A*02:03 |
0.75 |
20.58 |
32.38 |
54 |
HPV81 |
E7 |
LLTDTLSIV |
85 |
93 |
9 |
HLA-A*02:03 |
0.25 |
2.96 |
7.29 |
55 |
HPV81 |
E7 |
QLLTDTLSIV |
84 |
93 |
10 |
HLA-A*02:03 |
0.5 |
15.35 |
15.01 |
56 |
HPV81 |
E7 |
TTCGICRCLV |
59 |
68 |
10 |
HLA-A*68:02 |
0.55 |
26.99 |
31.21 |
57 |
HPV81 |
E7 |
LVEQAQQAY |
47 |
55 |
9 |
HLA-B*35:01 |
0.7 |
14.41 |
38.42 |