HPVomics

A therapeutic and epitome resource for Human Papillomaviruses

Efficient putative HR-HPVs E7 protein epitopes (MHC-I Binders)

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S.No.	HPV type	Target region	Peptide seuences	Start	End	Length	Allele	Percentile rank	ann_ic50	smm_ic50
1	HPV16	E7	LLMGTLGIV	82	90	9	HLA-A*02:03	0.2	2.86	3.05
2	HPV16	E7	GTLGIVCPI	85	93	9	HLA-A*32:01	0.3	12.13	36.14
3	HPV16	E7	GQAEPDRAHY	43	52	10	HLA-B*15:01	0.3	18.62	2.77
4	HPV16	E7	YMLDLQPET	11	19	9	HLA-A*02:01	0.4	21.23	20.56
5	HPV16	E7	LLMGTLGIV	82	90	9	HLA-A*02:01	0.5	24.84	26.13
6	HPV16	E7	LLMGTLGIV	82	90	9	HLA-A*02:06	0.85	20.13	34.16
7	HPV18	E7	QQLFLNTLSF	87	96	10	HLA-B*15:01	0.15	11.01	0.71
8	HPV18	E7	QLFLNTLSFV	88	97	10	HLA-A*02:03	0.2	8.04	5.72
9	HPV18	E7	QLFLNTLSF	88	96	9	HLA-A*32:01	0.3	15.3	12.79
10	HPV18	E7	HTMLCMCCK	59	67	9	HLA-A*11:01	0.35	19.59	36.17
11	HPV18	E7	HTMLCMCCK	59	67	9	HLA-A*68:01	0.6	25.32	36.43
12	HPV18	E7	FQQLFLNTL	86	94	9	HLA-A*02:06	0.7	15.81	22.26
13	HPV26	E7	MLMEDVSLV	89	97	9	HLA-A*02:01	0.1	2.46	1.56
14	HPV26	E7	MLMEDVSLV	89	97	9	HLA-A*02:03	0.1	1.8	0.65
15	HPV26	E7	MLMEDVSLV	89	97	9	HLA-A*02:06	0.15	3.38	4.23
16	HPV26	E7	QMLMEDVSLV	88	97	10	HLA-A*02:01	0.3	6.53	33
17	HPV26	E7	QMLMEDVSLV	88	97	10	HLA-A*02:03	0.4	4.41	26.56
18	HPV31	E7	ETPTLQDYV	4	12	9	HLA-A*68:02	0.2	4.52	9.85
19	HPV31	E7	LLMGSFGIV	82	90	9	HLA-A*02:03	0.25	3.9	4.62
20	HPV31	E7	GQAEPDTSNY	43	52	10	HLA-B*15:01	0.3	22.02	2.51
21	HPV31	E7	ILQELLMGSF	78	87	10	HLA-B*15:01	0.35	38.57	3.34
22	HPV31	E7	LLMGSFGIV	82	90	9	HLA-A*02:06	0.5	12.47	20.68
23	HPV31	E7	YVLDLQPEA	11	19	9	HLA-A*02:06	0.6	11.63	29.35
24	HPV31	E7	LLMGSFGIV	82	90	9	HLA-A*02:01	0.6	26.88	31.41
25	HPV33	E7	YPEPTDLYCY	16	25	10	HLA-B*35:01	0.15	17.46	32.95
26	HPV33	E7	LLMGTVNIV	82	90	9	HLA-A*02:03	0.2	3.48	4.3
27	HPV33	E7	LLMGTVNIV	82	90	9	HLA-A*02:01	0.4	11.72	15.17
28	HPV33	E7	GQAQPATADY	43	52	10	HLA-B*15:01	0.4	18.83	4.52
29	HPV35	E7	LLMGTFGIV	83	91	9	HLA-A*02:03	0.25	4.48	6.05
30	HPV35	E7	EITTLQDYV	4	12	9	HLA-A*68:02	0.4	10.92	27.64
31	HPV35	E7	GQAKPDTSNY	44	53	10	HLA-B*15:01	0.45	18.71	5.04
32	HPV35	E7	LLMGTFGIV	83	91	9	HLA-A*02:01	0.6	32.23	32.74
33	HPV35	E7	LLMGTFGIV	83	91	9	HLA-A*02:06	0.65	16.16	20.68
34	HPV35	E7	YVLDLEPEA	11	19	9	HLA-A*02:06	0.65	11.62	33.54
35	HPV39	E7	QLFMDSLGFV	91	100	10	HLA-A*02:03	0.15	3.9	6.81
36	HPV39	E7	QLFMDSLGFV	91	100	10	HLA-A*02:01	0.3	22.44	26.09
37	HPV39	E7	HTIQCSCCK	62	70	9	HLA-A*68:01	0.5	26.95	26.82
38	HPV39	E7	LFMDSLGFV	92	100	9	HLA-A*02:06	0.75	37.05	21.96
39	HPV39	E7	QQLFMDSLGF	90	99	10	HLA-B*15:01	0.8	15.91	15.32
40	HPV45	E7	RETLQEIVL	5	13	9	HLA-B*40:01	0.1	14.8	11.61
41	HPV45	E7	QLFLSTLSFV	89	98	10	HLA-A*02:03	0.15	7.35	4.23
42	HPV45	E7	QQLFLSTLSF	88	97	10	HLA-B*15:01	0.15	7.12	0.72
43	HPV45	E7	STLSFVCPW	93	101	9	HLA-A*32:01	0.2	8.37	9.08
44	HPV45	E7	QLFLSTLSF	89	97	9	HLA-A*32:01	0.3	24.23	24.49
45	HPV45	E7	STLSFVCPW	93	101	9	HLA-B*58:01	0.3	9.26	20.67
46	HPV51	E7	MLMGELSLV	86	94	9	HLA-A*02:03	0.1	1.86	0.95
47	HPV51	E7	MLMGELSLV	86	94	9	HLA-A*02:06	0.15	3.65	4.77
48	HPV51	E7	MLMGELSLV	86	94	9	HLA-A*02:01	0.2	3.06	4.56
49	HPV51	E7	QMLMGELSLV	85	94	10	HLA-A*02:01	0.25	8.56	25.91
50	HPV51	E7	QMLMGELSLV	85	94	10	HLA-A*02:03	0.25	4.39	14.5
51	HPV51	E7	QQMLMGELSL	84	93	10	HLA-B*15:01	0.95	39.06	18.67
52	HPV52	E7	AEQATSNYYI	47	56	10	HLA-B*44:02	0.25	34.89	39.25
53	HPV52	E7	MLLGTLQVV	84	92	9	HLA-A*02:06	0.3	6.71	14.37
54	HPV52	E7	GQAEQATSNY	45	54	10	HLA-B*15:01	0.3	19.11	2.74
55	HPV52	E7	MLLGTLQVV	84	92	9	HLA-A*02:01	0.4	9.37	17.26
56	HPV52	E7	MLLGTLQVV	84	92	9	HLA-A*02:03	0.6	8.6	20.18
57	HPV53	E7	MLMGTVELV	89	97	9	HLA-A*02:01	0.2	4.36	4.65
58	HPV53	E7	MLMGTVELV	89	97	9	HLA-A*02:03	0.2	2.9	2.77
59	HPV53	E7	MLMGTVELV	89	97	9	HLA-A*02:06	0.25	6.18	10.04
60	HPV53	E7	QMLMGTVELV	88	97	10	HLA-A*02:01	0.4	15.19	38.86
61	HPV53	E7	ILQQMLMGTV	85	94	10	HLA-A*02:03	0.55	17.45	19.46
62	HPV53	E7	MLMGTVELV	89	97	9	HLA-A*68:02	0.6	23.78	28.22
63	HPV56	E7	KQHTCYLIHV	54	63	10	HLA-A*02:06	0.2	8.69	25.4
64	HPV56	E7	LLMGALTVT	89	97	9	HLA-A*02:03	0.8	10.77	32.36
65	HPV58	E7	LLMGTCTIV	83	91	9	HLA-A*02:03	0.25	3.67	6.18
66	HPV58	E7	GQAQPATANY	44	53	10	HLA-B*15:01	0.3	16.22	1.93
67	HPV58	E7	LLMGTCTIV	83	91	9	HLA-A*02:01	0.4	11.66	14.59
68	HPV58	E7	LLMGTCTIV	83	91	9	HLA-A*02:06	0.95	28.65	38.69
69	HPV59	E7	QQLFMDTLSF	89	98	10	HLA-B*15:01	0.1	6.47	0.49
70	HPV59	E7	QLFMDTLSFV	90	99	10	HLA-A*02:03	0.15	3.02	5.32
71	HPV59	E7	QLFMDTLSFV	90	99	10	HLA-A*02:01	0.2	10.44	12.75
72	HPV59	E7	LFMDTLSFV	91	99	9	HLA-A*02:06	0.55	22.85	13.57
73	HPV59	E7	LFMDTLSFV	91	99	9	HLA-A*02:03	0.75	26.37	24.21
74	HPV66	E7	LLMGALTVT	89	97	9	HLA-A*02:03	0.8	10.77	32.36
75	HPV68	E7	QLFMDSLNFV	92	101	10	HLA-A*02:01	0.15	8.52	15.22
76	HPV68	E7	QLFMDSLNFV	92	101	10	HLA-A*02:03	0.15	3.91	10.26
77	HPV68	E7	QQLFMDSLNF	91	100	10	HLA-B*15:01	0.3	15.81	2.9
78	HPV68	E7	LFMDSLNFV	93	101	9	HLA-A*02:06	0.5	14.39	12.43
79	HPV73	E7	IEELLMGTL	78	86	9	HLA-B*40:01	0.15	11.76	31.83
80	HPV73	E7	LLMGTLGIV	81	89	9	HLA-A*02:03	0.2	2.86	3.05
81	HPV73	E7	RQAERECYR	44	52	9	HLA-A*31:01	0.25	10.8	11.79
82	HPV73	E7	LLMGTLGIV	81	89	9	HLA-A*02:01	0.5	24.84	26.13
83	HPV73	E7	LLMGTLGIV	81	89	9	HLA-A*02:06	0.85	20.13	34.16
84	HPV82	E7	CYRIKVHCCR	54	63	10	HLA-A*33:01	0.15	30.99	8.48
85	HPV82	E7	MLLGDLSLV	85	93	9	HLA-A*02:06	0.2	3.6	6.23
86	HPV82	E7	MLLGDLSLV	85	93	9	HLA-A*02:01	0.2	4.38	6.21
87	HPV82	E7	MLLGDLSLV	85	93	9	HLA-A*02:03	0.25	3.08	5.32
88	HPV82	E7	QMLLGDLSLV	84	93	10	HLA-A*02:01	0.3	15.99	28.94
89	HPV82	E7	QMLLGDLSLV	84	93	10	HLA-A*02:03	0.55	17.52	18.8