DrugRepV_0068 | Sunitinib | Antineoplastic and Immunomodulating Agents | Renal cell carcinoma | Gastrointestinal stromal tumor | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 28240606 |
DrugRepV_0069 | Erlotinib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 28240606 |
DrugRepV_0070 | Erlotinib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 28240606 |
DrugRepV_0073 | Sunitinib-Erlotinib | NA | NA | Ebola virus | rVSV-GP EBOV | NA | Flow cytometry | Decrease | NA | 28240606 |
DrugRepV_0074 | Sunitinib-Erlotinib | NA | NA | Ebola virus | Mouse adapted strain | NA | NA | Increase | NA | 28240606 |
DrugRepV_0198 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0199 | Chloroquine | Antiparasitic products, Insectisides and Repellents | malaria | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0200 | Maprotiline | Nervous System | Bipolar depression | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0201 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0202 | Azithromycin | Antiinfectives For Systemic Use | Microbial infections | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0203 | Clarithromycin | Antiinfectives For Systemic Use | Microbial infections | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0204 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27890675 |
DrugRepV_0205 | Toremifene-Clarithromycin-Posaconazole | NA | NA | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27890675 |
DrugRepV_0206 | Toremifene-Mefloquine-Posaconazole | NA | NA | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | NA | 27890675 |
DrugRepV_0207 | Chloroquine-Maprotiline-Azithromycin | NA | Malaria and Depression | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0208 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0209 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27890675 |
DrugRepV_0210 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0211 | Clarithromycin | Antiinfectives For Systemic Use | Microbial infections | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0212 | Maprotiline | Nervous System | Bipolar depression | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27890675 |
DrugRepV_0213 | Toremifene-Clarithromycin-Posaconazole | NA | NA | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (>90 %) | NA | 27890675 |
DrugRepV_0214 | Toremifene-Mefloquine-Posaconazole | NA | NA | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (74 %) | NA | 27890675 |
DrugRepV_0215 | Ouabain | Cardiovascular agents | Atrial fibrillation and flutter | Heart failure | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.48 ± 0.21 Ct) | Approved | 27801778 |
DrugRepV_0216 | Ouabain | Cardiovascular agents | Atrial fibrillation and flutter | Heart failure | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.73 ± 4.88 Ct) | Approved | 27801778 |
DrugRepV_0217 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.72 ± 0.18 Ct) | Investigational | 27801778 |
DrugRepV_0218 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?0.63 ± 1.39 Ct) | Investigational | 27801778 |
DrugRepV_0219 | Bemcentinib | Anticancer | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.05 ± 0.75 Ct) | Investigational | 27801778 |
DrugRepV_0220 | Bemcentinib | Anticancer | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?1.83 ± 1.13 Ct) | Investigational | 27801778 |
DrugRepV_0221 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.12 ± 0.27 Ct) | Approved | 27801778 |
DrugRepV_0222 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?7.91 ± 2.67 Ct) | Approved | 27801778 |
DrugRepV_0223 | Didanosine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?0.43 ± 3.87 Ct) | Approved | 27801778 |
DrugRepV_0224 | Didanosine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.52 ± 1.27 Ct) | Approved | 27801778 |
DrugRepV_0225 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.87 ± 0.22 Ct) | Approved, Investigational | 27801778 |
DrugRepV_0226 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.93 ± 0.25 Ct) | Approved, Investigational | 27801778 |
DrugRepV_0227 | Abacavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?1.54 ± 3.26 Ct) | Approved | 27801778 |
DrugRepV_0228 | Abacavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.95 ± 2.69 Ct) | Approved | 27801778 |
DrugRepV_0229 | Entecavir | Antiinfectives For Systemic Use | Hepatitis B virus | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.08 ± 0.20 Ct) | Approved | 27801778 |
DrugRepV_0230 | Entecavir | Antiinfectives For Systemic Use | Hepatitis B virus | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?4.44 ± 1.11 Ct) | Approved | 27801778 |
DrugRepV_0231 | JB1a | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?4.02 ± 0.13 Ct) | NA | 27801778 |
DrugRepV_0232 | JB1a | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?5.48 ± 0.50 Ct) | NA | 27801778 |
DrugRepV_0233 | Omeprazole | Alimentary Tract and Metabolism | Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (1.35 ± 1.35 Ct) | Approved | 27801778 |
DrugRepV_0234 | Omeprazole | Alimentary Tract and Metabolism | Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (2.21 ± 1.08 Ct) | Approved | 27801778 |
DrugRepV_0235 | Esomeprazole Magnesium | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (1.05 ± 0.79 Ct) | Approved | 27801778 |
DrugRepV_0236 | Esomeprazole Magnesium | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (1.62 ± 0.36 Ct) | Approved | 27801778 |
DrugRepV_0237 | Gleevec | Antineoplastic and Immunomodulating Agents | Leukemia | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.60 ± 0.63 Ct) | Approved | 27801778 |
DrugRepV_0238 | Gleevec | Antineoplastic and Immunomodulating Agents | Leukemia | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.49 ± 0.54 Ct) | Approved | 27801778 |
DrugRepV_0239 | Aimspro | NA | Multiple sclerosis | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.03 ± 0.95 Ct) | Phase II | 27801778 |
DrugRepV_0240 | Aimspro | NA | Multiple sclerosis | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?4.60 ± 1.15 Ct) | Phase II | 27801778 |
DrugRepV_0241 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (>10 Ct) | NA | 27801778 |
DrugRepV_0242 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (>10 Ct) | NA | 27801778 |
DrugRepV_0243 | D-LANA-14 | Antibacterial | Bacterial infections | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (>10 Ct) | NA | 27801778 |
DrugRepV_0244 | D-LANA-14 | Antibacterial | Bacterial infections | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (>10 Ct) | NA | 27801778 |
DrugRepV_0245 | Tasigna | Antineoplastic and Immunomodulating Agents | Myeloid leukemia | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (3.59 ± 0.57 Ct) | Approved, Investigational | 27801778 |
DrugRepV_0246 | Tasigna | Antineoplastic and Immunomodulating Agents | Myeloid leukemia | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?0.13 ± 0.33 Ct) | Approved, Investigational | 27801778 |
DrugRepV_0247 | Celgosivir | Antiviral | Hepatitis C virus | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.52 ± 0.21 Ct) | Investigational | 27801778 |
DrugRepV_0248 | Celgosivir | Antiviral | Hepatitis C virus | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.41 ± 0.12 Ct) | Investigational | 27801778 |
DrugRepV_0249 | Castanospermine | Antiviral | Dengue and Parainfluenza | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?1.58 ± 3.23 Ct) | Experimental | 27801778 |
DrugRepV_0250 | Castanospermine | Antiviral | Dengue and Parainfluenza | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?0.26 ± 4.11 Ct) | Experimental | 27801778 |
DrugRepV_0251 | Ouabain | Cardiovascular agents | Atrial fibrillation and flutter | Heart failure | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.33 ± 0.35 Ct) | Approved | 27801778 |
DrugRepV_0252 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.44 ± 0.06 Ct) | Investigational | 27801778 |
DrugRepV_0253 | Bemcentinib | Anticancer | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.90 ± 0.15 Ct) | Investigational | 27801778 |
DrugRepV_0254 | Omeprazole | Alimentary Tract and Metabolism | Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.86 ± 0.22 Ct) | Approved | 27801778 |
DrugRepV_0255 | Esomeprazole | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.78 ± 0.25 Ct) | Approved | 27801778 |
DrugRepV_0256 | Gleevec | Antineoplastic and Immunomodulating Agents | Leukemia | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (1.55 ± 0.20 Ct) | Approved | 27801778 |
DrugRepV_0257 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (1.54 ± 0.44 Ct) | NA | 27801778 |
DrugRepV_0258 | D-LANA-14 | Antibacterial | Bacterial infections | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Decrease (0.96 ± 0.19 Ct) | NA | 27801778 |
DrugRepV_0259 | Alvespimycin | NA | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | NA | No significant effect | Investigational | 27801778 |
DrugRepV_0260 | Bemcentinib | Anticancer | Cancer | Ebola virus | ME718-1976/Yambuku-Ecran | NA | NA | No significant effect | Investigational | 27801778 |
DrugRepV_0261 | NCK-8 | NA | NA | Ebola virus | ME718-1976/Yambuku-Ecran | NA | NA | No significant effect | NA | 27801778 |
DrugRepV_0317 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27622822 |
DrugRepV_0318 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Vet approved | 27622822 |
DrugRepV_0319 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0320 | Procainamide | Cardiovascular agents | Ventricular arrhythmias | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0321 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0322 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0323 | Clemastine | Respiratory System | Sneezing, rhinorrhea, pruritus and acrimation | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0324 | Benztropine | Nervous System | Parkinson disease | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0325 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0326 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0327 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0328 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0329 | Vincristine | Antineoplastic and Immunomodulating Agents | Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors) | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0330 | Thiothixene | Nervous System | Schizophrenia | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0331 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Vet approved | 27622822 |
DrugRepV_0332 | Fluphenazine | Nervous System | Psychosis | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0333 | Perphenazine | Nervous System | Psychosis | Nausea and vomiting in adults | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0334 | Promazine | Nervous System | Psychomotor agitation | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Vet approved | 27622822 |
DrugRepV_0335 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational | 27622822 |
DrugRepV_0336 | Tamoxifen | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0337 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0338 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0339 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved, Vet approved | 27622822 |
DrugRepV_0340 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0341 | Procainamide | Cardiovascular agents | Ventricular arrhythmias | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0342 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0343 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0344 | Benztropine | Nervous System | Parkinson disease | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0345 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0346 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0347 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0348 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0349 | Vincristine | Antineoplastic and Immunomodulating Agents | Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors) | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0350 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0351 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved, Investigational | 27622822 |
DrugRepV_0352 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0353 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | Increase | Approved | 27622822 |
DrugRepV_0354 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0355 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire | NA | Survival assay | Increase | Approved | 27622822 |
DrugRepV_0356 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0357 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | Ebola Zaire | NA | Survival assay | Increase | Approved | 27622822 |
DrugRepV_0358 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0359 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0360 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0361 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0362 | Benztropine | Nervous System | Parkinson disease | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0363 | Benztropine | Nervous System | Parkinson disease | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0364 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0365 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0366 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Mayinga | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0367 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Ebola Mayinga | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0368 | Amlodipine Besylate | Cardiovascular agents | Hypertension and chronic stable angina | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0369 | Azelastine | Respiratory System | Rhinitis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0370 | Benztropine Mesylate | Nervous System | Parkinson disease | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0371 | Cephapirin Sodium | Antibiotics | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0372 | Chlorhexidine Diacetate | Alimentary Tract and Metabolism | Disinfectant, oropharyngeal decontamination | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0373 | Ciclesonide | Respiratory System | Allergic rhinitis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0374 | Cilastatin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0375 | Clemastine Fumarate | Respiratory System | Allergic rhinitis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0376 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0377 | Clomipramine Hydrochloride | Nervous System | Obsessive-compulsive disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0378 | Danazol | Genito Urinary System and Sex Hormones | Endometriosis and fibrocystic breast disease | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0379 | Deslanoside | Cardiovascular agents | Congestive cardiac insufficiency, arrhythmias and heart failure | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0380 | Dicyclomine Hydrochloride | Alimentary Tract and Metabolism | Bowel/irritable bowel syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0381 | Digitoxin | Cardiovascular agents | Cardiac insufficiency, arrhythmias and heart failure | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0382 | Digoxin | Cardiovascular agents | Cardiac insufficiency, arrhythmias and heart failure | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0383 | Doxylamine Succinate | Respiratory System | Cough, vomiting and nausea | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0384 | Flucytosine | Antiinfectives For Systemic Use | Fungal infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0385 | Fluphenazine Hydrochloride | Nervous System | Psychosis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0386 | Fluvastatin | Cardiovascular agents | Cardiovascular disease (Coronary heart disease (CHD)) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0387 | Guanethidine Monosulfate | Cardiovascular agents | Hypertension | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0388 | Hexachlorophene | Dermatologicals | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0389 | Hycanthone | Antischistosomal | Parasitic infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26041706 |
DrugRepV_0390 | Hydroxyprogesterone Caproate | Genito Urinary System and Sex Hormones | Spontaneous preterm births | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0391 | Loperamide | Alimentary Tract and Metabolism | Chronic diarrhea associated with inflammatory bowel disease or gastroenteritis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0392 | Maprotiline Hydrochloride | Nervous System | Bipolar depression | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0393 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Vet approved | 26041706 |
DrugRepV_0394 | Methdilazine Hydrochloride | Respiratory System | Hypersensitivity reactions | Skin disorders | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0395 | Mycophenolate Mofetil | Immunosuppressant | Organ rejection (immunosuppressants) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0396 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0397 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0398 | Nonoxynol-9 | Gynaecological-agents | Contraception | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0399 | Paroxetine Hydrochloride Hemihydrate | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0400 | Pentamidine | Antiparasitic products, Insectisides and Repellents | Pneumonia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0401 | Perhexiline Maleate | Cardiovascular agents | Angina pectoris | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0402 | Perphenazine | Nervous System | Psychosis | Nausea and vomiting in adults | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0403 | Podofilox | Dermatologicals | External genital warts | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0404 | Prochlorperazine Edisylate | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Vet approved | 26041706 |
DrugRepV_0405 | Pyrvinium Pamoate | Antiparasitic products, Insectisides and Repellents | Pinworm infestations | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0406 | Quinacrine Dihydrochloride | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Investigational | 26041706 |
DrugRepV_0407 | Quinestrol | Gynaecological-agents | Hormone replacement therapy | Treating symptoms of menopause such as hot flashes | Breast cancer | Prostate cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0408 | Raloxifene Hydrochloride | Genito Urinary System and Sex Hormones | Osteoporosis | Corticosteroid-induced bone loss | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0409 | Sertraline Hydrochloride | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0410 | Sorafenib Tosylate | Antineoplastic and Immunomodulating Agents | Hepatocellular carcinoma | Renal cell carcinoma | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0411 | Sunitinib Malate | Antineoplastic and Immunomodulating Agents | Renal cell carcinoma | Gastrointestinal stromal tumor | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0412 | Tamoxifen | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0413 | Tamoxifen Citrate | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0414 | Thioridazine Hydrochloride | Nervous System | Schizophrenia | Anxiety disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0415 | Tioconazole | Dermatologicals; Genito Urinary System and Sex Hormones | Vulvovaginal candidiasis (moniliasis) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0416 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0417 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0418 | Trifluoperazine Hydrochloride | Nervous System | Schizophrenia and other psychotic disorders | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0419 | Triflupromazine Hydrochloride | Nervous System | Psychosis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0420 | Vinorelbine Tartrate Hydrate | Antineoplastic and Immunomodulating Agents | Breast cancer and non-small cell lung cancer (NSCLC) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26041706 |
DrugRepV_0421 | Aripiprazole | Nervous System | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0422 | Astemizole | Respiratory System | Allergies | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0423 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0424 | Azacitidine | Antineoplastic and Immunomodulating Agents | French-American-British myelodysplastic syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0425 | Benztropine | Nervous System | Parkinson disease | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0426 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0427 | Clemastine | Respiratory System | Allergic rhinitis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0428 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0429 | Clomipramine | Nervous System | Depression, schizophrenia, Tourette disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0430 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0431 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0432 | Flupentixol | Nervous System | Schizophrenia | Depression | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational, Withdrawn | 26041706 |
DrugRepV_0433 | Fluphenazine | Nervous System | Psychosis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0434 | Hycanthone | Antischistosomal | Parasitic infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26041706 |
DrugRepV_0435 | Lomerizine | Neurologic-agent | Migraine disorders | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26041706 |
DrugRepV_0436 | Maprotiline | Nervous System | Bipolar depression | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0437 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0438 | Pimozide | Nervous System | Tourette Disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0439 | Piperacetazine | Antipsychotic | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26041706 |
DrugRepV_0440 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0441 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Investigational | 26041706 |
DrugRepV_0442 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0443 | Simvastatin | Cardiovascular agents | Hypercholesterolemia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0444 | Strophanthin | Cardiovascular agents | Atrial fibrillation | Flutter | Heart failure | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0445 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0446 | Terconazole | Genito Urinary System and Sex Hormones | Candidiasis (a yeast-like fungal infection) of the vulva and vagina | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0447 | Thioridazine | Nervous System | Schizophrenia | Anxiety disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0448 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0449 | Aripiprazole | Nervous System | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0450 | Astemizole | Respiratory System | Allergies | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0451 | Azacitidine | Antineoplastic and Immunomodulating Agents | French-American-British myelodysplastic syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0452 | Benztropine | Nervous System | Parkinson disease | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0453 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0454 | Clemastine | Respiratory System | Allergic rhinitis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0455 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0456 | Clomipramine | Nervous System | Depression, schizophrenia, Tourette disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0457 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0458 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0459 | Flupentixol | Nervous System | Schizophrenia | Depression | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational, Withdrawn | 26041706 |
DrugRepV_0460 | Fluphenazine | Nervous System | Psychosis | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0461 | Hycanthone | Antischistosomal | Parasitic infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26041706 |
DrugRepV_0462 | Lomerizine | Neurologic-agent | Migraine disorders | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26041706 |
DrugRepV_0463 | Maprotiline | Nervous System | Bipolar depression | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0464 | Mycophenolate Mofetil | Immunosuppressant | Organ rejection (immunosuppressants) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0465 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0466 | Pimozide | Nervous System | Tourette Disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0467 | Piperacetazine | Antipsychotic | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26041706 |
DrugRepV_0468 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0469 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Investigational | 26041706 |
DrugRepV_0470 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0471 | Strophanthin | Cardiovascular agents | Atrial fibrillation | Flutter | Heart failure | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0472 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0473 | Terconazole | Genito Urinary System and Sex Hormones | Candidiasis (a yeast-like fungal infection) of the vulva and vagina | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0474 | Thioridazine | Nervous System | Schizophrenia | Anxiety disorder | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0475 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0476 | Vinorelbine | Antineoplastic and Immunomodulating Agents | Breast cancer and non-small cell lung cancer (NSCLC) | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0477 | Aripiprazole | Nervous System | Schizophrenia | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0478 | Astemizole | Respiratory System | Allergies | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0479 | Atovaquone | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Approved | 26041706 |
DrugRepV_0480 | Azacitidine | Antineoplastic and Immunomodulating Agents | French-American-British myelodysplastic syndrome | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Approved | 26041706 |
DrugRepV_0481 | Benztropine | Nervous System | Parkinson disease | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0482 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0483 | Clemastine | Respiratory System | Allergic rhinitis | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0484 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0485 | Clomipramine | Nervous System | Depression, schizophrenia, Tourette disorder | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0486 | Dasatinib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0487 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0488 | Flupentixol | Nervous System | Schizophrenia | Depression | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Investigational, Withdrawn | 26041706 |
DrugRepV_0489 | Fluphenazine | Nervous System | Psychosis | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0490 | Hycanthone | Antischistosomal | Parasitic infections | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Experimental | 26041706 |
DrugRepV_0491 | Lomerizine | Neurologic-agent | Migraine disorders | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Experimental | 26041706 |
DrugRepV_0492 | Maprotiline | Nervous System | Bipolar depression | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Investigational | 26041706 |
DrugRepV_0493 | Mycophenolate Mofetil | Immunosuppressant | Organ rejection (immunosuppressants) | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Approved, Investigational | 26041706 |
DrugRepV_0494 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Investigational | 26041706 |
DrugRepV_0495 | Pimozide | Nervous System | Tourette Disorder | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0496 | Piperacetazine | Antipsychotic | Schizophrenia | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | NA | 26041706 |
DrugRepV_0497 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0498 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Investigational | 26041706 |
DrugRepV_0499 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0500 | Simvastatin | Cardiovascular agents | Hypercholesterolemia | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0501 | Strophanthin | Cardiovascular agents | Atrial fibrillation | Flutter | Heart failure | Ebola virus | EBOV-VLP | NA | Flow cytometry | No significant effect | Approved | 26041706 |
DrugRepV_0502 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0503 | Terconazole | Genito Urinary System and Sex Hormones | Candidiasis (a yeast-like fungal infection) of the vulva and vagina | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0504 | Thioridazine | Nervous System | Schizophrenia | Anxiety disorder | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0505 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved, Investigational | 26041706 |
DrugRepV_0506 | Vinorelbine | Antineoplastic and Immunomodulating Agents | Breast cancer and non-small cell lung cancer (NSCLC) | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0507 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | ma-EBOV | NA | Survival assay | Increase | Approved, Withdrawn | 26041706 |
DrugRepV_0508 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | ma-EBOV | NA | Survival assay | Increase | Approved | 26041706 |
DrugRepV_0509 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | EBOV/Kik | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0510 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | SUDV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0511 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | MARV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0512 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | RAVV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Withdrawn | 26041706 |
DrugRepV_0513 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | EBOV/Kik | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0514 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | EBOV/May | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0515 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | SUDV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0516 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | MARV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0517 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | RAVV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0518 | Vinblastine | Antineoplastic and Immunomodulating Agents | Cancer (Hodgkin lymphoma | Non-Hodgkin's lymphoma |Testicular | Breast | Lung (Non-small cell lung cancer) | Head and neck | Bladder cancers | Melanoma | Soft tissue sarcoma |Kaposi's sarcoma | Mycosis fungoides (t-cell lymphoma) | Choriocarcinoma) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0519 | Vinorelbine | Antineoplastic and Immunomodulating Agents | Breast cancer and non-small cell lung cancer (NSCLC) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0520 | Vincristine | Antineoplastic and Immunomodulating Agents | Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0521 | Colchicine | Musculo-Skeletal System | Gout | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0522 | Nocodazole | Anticancer | NA | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26038505 |
DrugRepV_0523 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0524 | Tamoxifen | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0525 | Digoxin | Cardiovascular agents | Cardiac insufficiency, arrhythmias and heart failure | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0526 | Clemastine | Respiratory System | Allergic rhinitis | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0527 | Raloxifene/Evista | Genito Urinary System and Sex Hormones | Osteoporosis | Corticosteroid-induced bone loss | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0528 | Sunitinib | Antineoplastic and Immunomodulating Agents | Renal cell carcinoma | Gastrointestinal stromal tumor | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0529 | Thiothixene | Nervous System | Schizophrenia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0530 | Dronedarone | Cardiovascular agents | Arrhythmia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0531 | Maprotiline | Nervous System | Bipolar depression | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0532 | Daunorubicin | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0533 | Benztropine | Nervous System | Parkinson disease | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0534 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0535 | Mebendazole | Antiparasitic products, Insectisides and Repellents | Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Vet approved | 26038505 |
DrugRepV_0536 | Trifluoperazine | Nervous System | Schizophrenia and other psychotic disorders | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0537 | Clarithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0538 | Albendazole | Antiparasitic products, Insectisides and Repellents | Parasitic infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0539 | Clomipramine | Nervous System | Depressive disorder | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0540 | Propafenone | Cardiovascular agents | Arrhythmia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0541 | Carfilzomib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0542 | Deslanoside | Cardiovascular agents | Arrhythmia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0543 | Maduramicin | Antiprotozoal | Coccidiosis | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Vet approved | 26038505 |
DrugRepV_0544 | Cepharanthine | Antiinflammatory and antineoplastic | Inflammatory disorders/Cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26038505 |
DrugRepV_0545 | Clomiphene | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0546 | Oxibendazole | Antiparasitic | Helminth intestinal infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Investigational, Vet approved | 26038505 |
DrugRepV_0547 | Daunorubicin | Antineoplastic and Immunomodulating Agents | Microbial infections and cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0548 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0549 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0550 | Mefloquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0551 | Tilorone | NA | Acquired immunodeficiency syndrome | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0552 | Bazedoxifene | Genito Urinary System and Sex Hormones | Postmenopausal osteoporosis | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0553 | Topotecan | Antineoplastic and Immunomodulating Agents | Ovarian cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0554 | Bosutinib | Antineoplastic and Immunomodulating Agents | Cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0555 | Thioproperazine | Nervous System | Psychosis | Acute and Chronic schizophrenia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0556 | Spiramycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0557 | Mibefradil | Cardiovascular agents | Angina | High blood pressure | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Investigational, Withdrawn | 26038505 |
DrugRepV_0558 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0559 | Nitrovin | NA | NA | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26038505 |
DrugRepV_0560 | Bifemelane | Nervous System | Depressive disorder | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26038505 |
DrugRepV_0561 | Bitolterol | Respiratory System | Bronchodilator | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Withdrawn | 26038505 |
DrugRepV_0562 | Proglumetacin | Musculo-Skeletal System | Inflammatory disorders | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Experimental | 26038505 |
DrugRepV_0563 | Aprindine | Cardiovascular agents | Arrhythmia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0564 | Cyclomethycaine | NA | Anesthesia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Withdrawn | 26038505 |
DrugRepV_0565 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational, Vet approved | 26038505 |
DrugRepV_0566 | Alverine Citrate | Alimentary Tract and Metabolism | Muscle spasms | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0567 | Azaclorzine | NA | Anginal | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26038505 |
DrugRepV_0568 | Salmeterol | Respiratory System | Asthma | Chronic obstructive pulmonary disease | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0569 | Piperacetazine | Antipsychotic | Schizophrenia | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | NA | 26038505 |
DrugRepV_0570 | Gefitinib | Antineoplastic and Immunomodulating Agents | Non-small cell lung cancer | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0571 | Imipramine | Nervous System | Depression | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0572 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0573 | Nilotinib | Antineoplastic and Immunomodulating Agents | Leukemias | Chronic myeloid leukemia (CML) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26038505 |
DrugRepV_0581 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0582 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0583 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0584 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0585 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | EBOV/Kik | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0586 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | EBOV/May | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0587 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | SUDV | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0588 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | MARV | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0589 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | RAVV | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0590 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV/Kik | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0591 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV/May | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0592 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | SUDV | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0593 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | MARV | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0594 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | RAVV | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0595 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | EBOV/Kik | NA | Real-time PCR | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0596 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | SUDV | NA | Real-time PCR | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0597 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | MARV | NA | Real-time PCR | Decrease (50 %) | Approved | 23785035 |
DrugRepV_0598 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV/Kik | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0599 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | SUDV | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0600 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | MARV | NA | Real-time PCR | Decrease (50 %) | Approved, Investigational | 23785035 |
DrugRepV_0601 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | ma-EBOV | NA | NA | Increase | Approved | 23785035 |
DrugRepV_0602 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | ma-EBOV | NA | NA | Increase | Approved, Investigational | 23785035 |
DrugRepV_0603 | Clomiphene Citrate | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | VLP-GP | NA | Flow cytometry | Decrease (93 %) | Approved | 23785035 |
DrugRepV_0604 | Toremifene Citrate | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | VLP-GP | NA | Flow cytometry | Decrease (95 %) | Approved, Investigational | 23785035 |
DrugRepV_0644 | Amlodipine | Cardiovascular agents | Hypertension | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (93 %) | Approved | 23577127 |
DrugRepV_0645 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0646 | Biperiden | Nervous System | Parkinson disease | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (89 %) | Approved | 23577127 |
DrugRepV_0647 | Carprofen | Anti-inflammatory | Joint pain | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (88 %) | Approved, Withdrawn | 23577127 |
DrugRepV_0648 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0649 | Dexbrompheniramine | Respiratory System | Allergies | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (80 %) | Approved | 23577127 |
DrugRepV_0650 | Dibucaine | Nervous System | Anesthesia | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (93 %) | Approved | 23577127 |
DrugRepV_0651 | Diphenoxylate | Alimentary Tract and Metabolism | Diarrhea | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (95 %) | Approved | 23577127 |
DrugRepV_0652 | Diphenylpyraline | Respiratory System | Allergies | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (85 %) | Approved | 23577127 |
DrugRepV_0653 | Dipivefrin | Sensory Organ | Glaucoma | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (90 %) | Approved | 23577127 |
DrugRepV_0654 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (91 %) | Approved | 23577127 |
DrugRepV_0655 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved | 23577127 |
DrugRepV_0656 | Estradiol | Genito Urinary System and Sex Hormones | Vulvar and vaginal atrophy | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved | 23577127 |
DrugRepV_0657 | Fluoxetine | Nervous System | Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved, Vet approved | 23577127 |
DrugRepV_0658 | Ketotifen | Respiratory System | Atopic asthma | Conjunctivitis | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0659 | Levopropoxyphene | Respiratory-Tract-agents | Cough and associated respiratory tract disorders | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (89 %) | Withdrawn | 23577127 |
DrugRepV_0660 | Mycophenolate Mofetil | Immunosuppressant | Organ rejection (immunosuppressants) | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (81 %) | Approved, Investigational | 23577127 |
DrugRepV_0661 | Oxyphencyclimine | Alimentary Tract and Metabolism | Peptic ulcers | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (89 %) | Approved | 23577127 |
DrugRepV_0662 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (89 %) | Approved, Investigational | 23577127 |
DrugRepV_0663 | Penbutolol | Cardiovascular agents | Arterial hypertension | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (81 %) | Approved, Investigational | 23577127 |
DrugRepV_0664 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (93 %) | Approved | 23577127 |
DrugRepV_0665 | Protriptyline | Nervous System | Depressive disorder | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (80 %) | Approved | 23577127 |
DrugRepV_0666 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (96 %) | Approved, Investigational | 23577127 |
DrugRepV_0667 | Trihexyphenidyl | Nervous System | Parkinson Disease | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (91 %) | Approved | 23577127 |
DrugRepV_0668 | Amlodipine | Cardiovascular agents | Hypertension | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (93 %) | Approved | 23577127 |
DrugRepV_0669 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (99 %) | Approved | 23577127 |
DrugRepV_0670 | Biperiden | Nervous System | Parkinson disease | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved | 23577127 |
DrugRepV_0671 | Carprofen | Anti-inflammatory | Joint pain | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (94 %) | Approved, Withdrawn | 23577127 |
DrugRepV_0672 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0673 | Dexbrompheniramine | Respiratory System | Allergies | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (85 %) | Approved | 23577127 |
DrugRepV_0674 | Dibucaine | Nervous System | Anesthesia | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (99 %) | Approved | 23577127 |
DrugRepV_0675 | Diphenoxylate | Alimentary Tract and Metabolism | Diarrhea | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (96 %) | Approved | 23577127 |
DrugRepV_0676 | Diphenylpyraline | Respiratory System | Allergies | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (96 %) | Approved | 23577127 |
DrugRepV_0677 | Dipivefrin | Sensory Organ | Glaucoma | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (94 %) | Approved | 23577127 |
DrugRepV_0678 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (99 %) | Approved | 23577127 |
DrugRepV_0679 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (96 %) | Approved | 23577127 |
DrugRepV_0680 | Estradiol | Genito Urinary System and Sex Hormones | Vulvar and vaginal atrophy | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (93 %) | Approved | 23577127 |
DrugRepV_0681 | Fluoxetine | Nervous System | Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (96 %) | Approved, Vet approved | 23577127 |
DrugRepV_0682 | Ketotifen | Respiratory System | Atopic asthma | Conjunctivitis | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (99 %) | Approved | 23577127 |
DrugRepV_0683 | Levopropoxyphene | Respiratory-Tract-agents | Cough and associated respiratory tract disorders | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Withdrawn | 23577127 |
DrugRepV_0684 | Mycophenolate Mofetil | Immunosuppressant | Organ rejection (immunosuppressants) | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (91 %) | Approved, Investigational | 23577127 |
DrugRepV_0685 | Oxyphencyclimine | Alimentary Tract and Metabolism | Peptic ulcers | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (95 %) | Approved | 23577127 |
DrugRepV_0686 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved, Investigational | 23577127 |
DrugRepV_0687 | Penbutolol | Cardiovascular agents | Arterial hypertension | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved, Investigational | 23577127 |
DrugRepV_0688 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (95 %) | Approved | 23577127 |
DrugRepV_0689 | Protriptyline | Nervous System | Depressive disorder | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (83 %) | Approved | 23577127 |
DrugRepV_0690 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved, Investigational | 23577127 |
DrugRepV_0691 | Trihexyphenidyl | Nervous System | Parkinson Disease | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (97 %) | Approved | 23577127 |
DrugRepV_0692 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0693 | Biperiden | Nervous System | Parkinson disease | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0694 | Carprofen | Anti-inflammatory | Joint pain | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved, Withdrawn | 23577127 |
DrugRepV_0695 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease | Approved | 23577127 |
DrugRepV_0696 | Dibucaine | Nervous System | Anesthesia | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0697 | Diphenoxylate | Alimentary Tract and Metabolism | Diarrhea | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease | Approved | 23577127 |
DrugRepV_0698 | Diphenylpyraline | Respiratory System | Allergies | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease | Approved | 23577127 |
DrugRepV_0699 | Dipivefrin | Sensory Organ | Glaucoma | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0700 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0701 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0702 | Estradiol | Genito Urinary System and Sex Hormones | Vulvar and vaginal atrophy | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0703 | Fluoxetine | Nervous System | Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved, Vet approved | 23577127 |
DrugRepV_0704 | Ketotifen | Respiratory System | Atopic asthma | Conjunctivitis | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease | Approved | 23577127 |
DrugRepV_0705 | Mycophenolate Mofetil | Immunosuppressant | Organ rejection (immunosuppressants) | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved, Investigational | 23577127 |
DrugRepV_0706 | Oxyphencyclimine | Alimentary Tract and Metabolism | Peptic ulcers | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0707 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved, Investigational | 23577127 |
DrugRepV_0708 | Trihexyphenidyl | Nervous System | Parkinson Disease | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0709 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0710 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase virus entry activity | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0711 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0712 | Aminoquinoline-13 | NA | Malaria | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0713 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0714 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0715 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0716 | Aminoquinoline-13 | NA | Malaria | Marburg virus | Musoke | NA | Immunoflourescence assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0717 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0718 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0719 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0720 | Aminoquinoline-13 | NA | Malaria | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0721 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0722 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0723 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 23577127 |
DrugRepV_0724 | Aminoquinoline-13 | NA | Malaria | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | Decrease (50 %) | NA | 23577127 |
DrugRepV_0725 | Prochlorperazine | Nervous System | Nausea | Vomiting | Schizophrenia | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved | 23577127 |
DrugRepV_0726 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | ma-EBOV | NA | NA | Increase | Approved | 23577127 |
DrugRepV_0727 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved | 23577127 |
DrugRepV_0728 | Erythromycin ethylsuccinate | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved | 23577127 |
DrugRepV_0729 | Amlodipine | Cardiovascular agents | Hypertension | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved | 23577127 |
DrugRepV_0730 | Fluoxetine | Nervous System | Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved, Vet approved | 23577127 |
DrugRepV_0731 | Penbutolol | Cardiovascular agents | Arterial hypertension | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved, Investigational | 23577127 |
DrugRepV_0756 | Favipiravir | Antiviral | Influenza virus | Ebola virus | NA | NA | NA | Increase (7 %) | Investigational | 26930627 |
DrugRepV_0757 | Favipiravir | Antiviral | Influenza virus | Ebola virus | NA | NA | Real-time PCR | No significant effect | Investigational | 26930627 |
DrugRepV_0758 | Favipiravir | Antiviral | Influenza virus | Ebola virus | NA | NA | NA | Decrease (33 %) | Investigational | 26930627 |
DrugRepV_0759 | Favipiravir | Antiviral | Influenza virus | Ebola virus | NA | NA | Real-time PCR | Decrease | Investigational | 26930627 |
DrugRepV_1615 | Quinacrine Hydrochloride | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Investigational | 26834994 |
DrugRepV_1616 | Pyronaridine tetraphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Approved | 26834994 |
DrugRepV_1617 | Tilorone Dihydrochloride | NA | Viral infections | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | NA | 26834994 |
DrugRepV_1618 | Chloroquine Diphosphate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Recombinant, infectious Ebola virus encoding green fluorescent protein | NA | Cell based assay | Decrease (50 %) | Approved | 26834994 |
DrugRepV_2015 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2016 | Tamoxifen | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2017 | Clemastine | Respiratory System | Allergic rhinitis | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2018 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved, Investigational | 26585243 |
DrugRepV_2019 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved, Investigational | 26585243 |
DrugRepV_2020 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved, Investigational | 26585243 |
DrugRepV_2021 | Clomiphene | Genito Urinary System and Sex Hormones | Cancer | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2022 | Securinine | Anticancer | NA | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | NA | 26585243 |
DrugRepV_2023 | Glafenine | Nervous System | Inflammatory disease | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | NA | 26585243 |
DrugRepV_2024 | Oxeladin | Respiratory-Tract-agents | Cough | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Withdrawn | 26585243 |
DrugRepV_2025 | Pimethixene Maleate | Respiratory System | NA | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2026 | Artemisinin | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Experimental | 26585243 |
DrugRepV_2027 | Indoprofen | Musculo-Skeletal System | Inflammatory disease | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Withdrawn | 26585243 |
DrugRepV_2028 | Iodoquinol | Genito Urinary System and Sex Hormones | Amoebiasis | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2029 | Levonordefrin | NA | Dental disorders | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2030 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (90 %) | Approved | 26585243 |
DrugRepV_2031 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2032 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (87.5 %) | Approved | 26585243 |
DrugRepV_2033 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (95 %) | Approved | 26585243 |
DrugRepV_2034 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | No significant effect (0 %) | Approved | 26585243 |
DrugRepV_2071 | Diphenhydramine | Dermatologicals and Respiratory System | Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2072 | Chlorcyclizine | Respiratory System | Allergic rhinitis | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2073 | Diphenhydramine | Dermatologicals and Respiratory System | Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2074 | Chlorcyclizine | Respiratory System | Allergic rhinitis | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2075 | Cetirizine | Respiratory System | Allergic rhinitis | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | No significant decrease (50 %) | Approved | 29981374 |
DrugRepV_2076 | Cetirizine | Respiratory System | Allergic rhinitis | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | Approved | 29981374 |
DrugRepV_2077 | Fexofenadine | Respiratory System | Allergic rhinitis | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | No significant decrease (50 %) | Approved, Investigational | 29981374 |
DrugRepV_2078 | Fexofenadine | Respiratory System | Allergic rhinitis | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | Approved, Investigational | 29981374 |
DrugRepV_2079 | Tiotidine | NA | NA | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2080 | Tiotidine | NA | NA | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2081 | Impentamine | NA | NA | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2082 | Impentamine | NA | NA | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | NA | 29981374 |
DrugRepV_2083 | JNJ7777120 | Anti-inflammatory | Pruritus (itching) | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | NA | 29981374 |
DrugRepV_2084 | JNJ7777120 | Anti-inflammatory | Pruritus (itching) | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | NA | 29981374 |
DrugRepV_2085 | Nordiphenhydramine | NA | NA | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | NA | 29981374 |
DrugRepV_2086 | Nordiphenhydramine | NA | NA | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | NA | 29981374 |
DrugRepV_2087 | Orphenadrine | Nervous System | Parkinson's disease | Muscle spasm | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2088 | Orphenadrine | Nervous System | Parkinson's disease | Muscle spasm | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2089 | Chlorphenoxamine | Respiratory System | Parkinson's | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Withdrawn | 29981374 |
DrugRepV_2090 | Chlorphenoxamine | Respiratory System | Parkinson's | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Withdrawn | 29981374 |
DrugRepV_2091 | Carbinoxamine | Respiratory System | Allergic rhinitis | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2092 | Carbinoxamine | Respiratory System | Allergic rhinitis | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2093 | Doxylamine | Respiratory System | Allergies and an antitussive, antiemetic, and hypnotic | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2094 | Doxylamine | Respiratory System | Allergies and an antitussive, antiemetic, and hypnotic | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | No significant decrease (50 %) | Approved | 29981374 |
DrugRepV_2095 | Hydroxyzine | Nervous System | Anxiety | Tension | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2096 | Hydroxyzine | Nervous System | Anxiety | Tension | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2097 | Cyclizine | Respiratory System | Nausea, vomiting, and dizziness | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2098 | Cyclizine | Respiratory System | Nausea, vomiting, and dizziness | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2099 | Buclizine | Respiratory System | Nausea, vomiting, and dizziness | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2100 | Buclizine | Respiratory System | Nausea, vomiting, and dizziness | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2101 | Meclizine | Respiratory System | Nausea | Vomiting | Motion sickness | Vertigo | Ebola virus | HIV/EBOV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2102 | Meclizine | Respiratory System | Nausea | Vomiting | Motion sickness | Vertigo | Marburg virus | HIV/MARV | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2103 | Diphenhydramine | Dermatologicals and Respiratory System | Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite | Ebola virus | EBOV/kikwit | NA | Immunoblot assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2104 | Chlorcyclizine | Respiratory System | Allergic rhinitis | Ebola virus | EBOV/kikwit | NA | Immunoblot assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2105 | Diphenhydramine | Dermatologicals and Respiratory System | Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite | Ebola virus | EBOV/kikwit | NA | Immunoblot assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_2106 | Chlorcyclizine | Respiratory System | Allergic rhinitis | Ebola virus | EBOV/kikwit | NA | Immunoblot assay | Decrease (50 %) | Approved | 29981374 |
DrugRepV_3566 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV/Mak | NA | Luminescence assay | Decrease (50 %) | Approved, Investigational | 30016444 |
DrugRepV_3567 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV/Mak | NA | Luminescence assay | Decrease (50 %) | Approved, Investigational | 30016444 |
DrugRepV_3568 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV/Mak | NA | Luminescence assay | Decrease (50 %) | Approved, Investigational | 30016444 |
DrugRepV_3569 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV/May-GPA | NA | Luminescence assay | Decrease (50 %) | Approved, Investigational | 30016444 |
DrugRepV_3570 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV/May-GPA | NA | Luminescence assay | Decrease (50 %) | Approved, Investigational | 30016444 |
DrugRepV_3571 | Tamoxifen | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3572 | Trifluoperazine | Nervous System | Schizophrenia and other psychotic disorders | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3573 | Clomipramine | Nervous System | Depression, schizophrenia, Tourette disorder | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3574 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 30149038 |
DrugRepV_3575 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 30149038 |
DrugRepV_3576 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 30149038 |
DrugRepV_3577 | Tamoxifen | Antineoplastic and Immunomodulating Agents | Breast cancer | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3578 | AY9944 | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3579 | Paroxetine | Nervous System | Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD) | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 30149038 |
DrugRepV_3580 | Thioridazine | Nervous System | Schizophrenia | Anxiety disorder | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Withdrawn | 30149038 |
DrugRepV_3581 | GBR-12783 | NA | Psychosis | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3582 | Tabimorelin | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3583 | Asenapine | Nervous System | Psychosis | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3584 | Camylofine | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3585 | Bisacodyl | Alimentary Tract and Metabolism | Colon cleansing | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3586 | Bisacodyl | Alimentary Tract and Metabolism | Colon cleansing | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3587 | ML9 | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3588 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3589 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved | 30149038 |
DrugRepV_3590 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 30149038 |
DrugRepV_3591 | Bepridil | Cardiovascular agents | Hypertension and angina | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Withdrawn | 30149038 |
DrugRepV_3592 | Amiodarone | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 30149038 |
DrugRepV_3593 | Iminodyn 17 | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3594 | Nobiletin | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3595 | Ferroquine | Antimalarial | Malaria | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3596 | N-Acetyl-L-leucyl- L- leucyl-L- methional | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3597 | Calpeptin | NA | NA | Ebola virus | EBOV trVLP | NA | Luciferase reporter assay | Decrease (50 %) | NA | 30149038 |
DrugRepV_3627 | Cyanovirin-N | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 15073681 |
DrugRepV_3628 | Cyanovirin-N | NA | NA | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 15073681 |
DrugRepV_3629 | Cyanovirin-N | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 15073681 |
DrugRepV_3630 | N-methyl-5,7-dinitro-N-propylquinolin-8-amine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3631 | 2-[3-(4-chlorophenyl)-1-(3-methoxyphenyl)-3-oxopropyl]propanedinitrile | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3632 | (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,9,15(20)-pentaene-14,18-dione | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3633 | 2-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3634 | N-(3,4-dichlorophenyl)-5-nitrofuran-2-carboxamide | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3635 | 7-[(furan-2-yl)methyl]-3-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-imine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3636 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3637 | N,N-bis(4-methylphenyl)pyridin-3-amine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3638 | N-methyl-5,7-dinitro-N-propylquinolin-8-amine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3639 | 2-[3-(4-chlorophenyl)-1-(3-methoxyphenyl)-3-oxopropyl]propanedinitrile | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3640 | (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,9,15(20)-pentaene-14,18-dione | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3641 | 2-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3642 | N-(3,4-dichlorophenyl)-5-nitrofuran-2-carboxamide | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3643 | 7-[(furan-2-yl)methyl]-3-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-imine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3644 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3645 | N,N-bis(4-methylphenyl)pyridin-3-amine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3646 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | Zaire | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3647 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3652 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3653 | 2-methyl-4-phenyl-1H-naphtho[2,3-b][1,4]diazepine hydrochloride | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3654 | 2-(4-chlorophenyl)-7,8-dimethyl-4-(trifluoromethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3655 | 2-(1,1,2,2,2-pentafluoroethyl)-4-phenyl-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3656 | 7,8-dichloro-2-(1,1,2,2,2-pentafluoroethyl)-4-phenyl-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3657 | 2-[4-(trifluoromethyl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3658 | 2-(4-methylphenyl)-4-(trifluoromethyl)-3H-1,5-benzodiazepine | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3659 | 4-methoxy-2-[4-(trifluoromethyl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3660 | 2-[4-(thiophen-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3661 | 4-chloro-2-[4-(furan-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3662 | 4-methoxy-2-[4-(thiophen-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3663 | 2-[4-(furan-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3664 | 2-[4-(3-nitrophenyl)-3H-1,5-benzodiazepin-2-yl]phenol | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3665 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (90 %) | NA | 21270170 |
DrugRepV_3666 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (50 %) | NA | 21270170 |
DrugRepV_3667 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (100 %) | NA | 21270170 |
DrugRepV_3668 | 2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine | NA | NA | Marburg virus | Lake Victoria | NA | Luciferase reporter assay | Decrease (98 %) | NA | 21270170 |
DrugRepV_3671 | 2,6-bis[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenol | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (100 %) | NA | 22027648 |
DrugRepV_3672 | NSC 62914 | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease | NA | 22027648 |
DrugRepV_3673 | NSC 62914 | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 22027648 |
DrugRepV_3674 | Trolox | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (45 %) | NA | 22027648 |
DrugRepV_3675 | Trolox | NA | NA | Marburg virus | NA | NA | RT-PCR | Decrease (70 %) | NA | 22027648 |
DrugRepV_3676 | NSC 62914 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (98 %) | NA | 22027648 |
DrugRepV_3679 | NSC 62914 | NA | NA | Ebola virus | NA | NA | NA | Decrease | NA | 22027648 |
DrugRepV_3680 | NSC 62914 | NA | NA | Marburg virus | NA | NA | NA | Decrease | NA | 22027648 |
DrugRepV_3681 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine tetrahydrochloride | NA | NA | Ebola virus | Zaire-95 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3682 | N5,N14-bis[2-(morpholin-4-yl)ethyl]-3,12-bis({[2-(morpholin-4-yl)ethyl]amino})-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-5,14-dicarboxamide; hexakis(trifluoroacet | NA | NA | Ebola virus | Zaire-95 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3683 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine | NA | NA | Ebola virus | Zaire-95 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3684 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine tetrahydrochloride | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3685 | N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 23012625 |
DrugRepV_3686 | BCX4430 | NA | Ebola virus | Marburg virus | Musoke | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3687 | BCX4430 | NA | Ebola virus | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3688 | BCX4430 | NA | Ebola virus | Marburg virus | Angola | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3689 | BCX4430 | NA | Ebola virus | Ebola virus | Kikwit | NA | RT-PCR | Decrease (50 %) | Investigational | 24590073 |
DrugRepV_3697 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 24713118 |
DrugRepV_3698 | 6-Azauridine | NA | Cancer | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 24713118 |
DrugRepV_3699 | 2-C-Methylcytidine | NA | Hepatitis C virus | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | Experimental | 24713118 |
DrugRepV_3700 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 24713118 |
DrugRepV_3701 | 6-Azauridine | NA | Cancer | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 24713118 |
DrugRepV_3702 | 2-C-Methylcytidine | NA | Hepatitis C virus | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Experimental | 24713118 |
DrugRepV_3703 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Marburg virus | NA | NA | NA | Decrease (83 %) | Approved | 24713118 |
DrugRepV_3704 | 6-Azauridine | NA | Cancer | Marburg virus | NA | NA | NA | Decrease (98 %) | NA | 24713118 |
DrugRepV_3705 | Chloroquine | Malaria | Malaria | Marburg virus | NA | NA | NA | Decrease (99.9 %) | Approved | 24713118 |
DrugRepV_3706 | Imatinib Methanesulfonate Salt | Antineoplastic and Immunomodulating Agents | NA | Marburg virus | NA | NA | NA | Decrease (99 %) | Approved | 24713118 |
DrugRepV_3707 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | NA | NA | NA | Decrease (0 %) | Approved | 24713118 |
DrugRepV_3708 | 6-Azauridine | NA | Cancer | Ebola virus | NA | NA | NA | Decrease (99 %) | NA | 24713118 |
DrugRepV_3709 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | NA | Decrease (99.9 %) | Approved | 24713118 |
DrugRepV_3710 | Imatinib Methanesulfonate Salt | Antineoplastic and Immunomodulating Agents | NA | Ebola virus | NA | NA | NA | Decrease (95 %) | Approved | 24713118 |
DrugRepV_3715 | C795-0925 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3716 | D011-2120 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3717 | F694-1532 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3718 | G202-0362 | NA | NA | Ebola virus | Zaire | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3719 | C795-0925 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3720 | D011-2120 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3721 | F694-1532 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3722 | G202-0362 | NA | NA | Marburg virus | Ci67 | NA | RT-PCR | Decrease (50 %) | NA | 25144302 |
DrugRepV_3735 | OSU-03012 | Anticancer | Brain cancer | Ebola virus | NA | NA | GFP assay | Decrease (50 %) | NA | 25986249 |
DrugRepV_3736 | OSU-03012 | Anticancer | Brain cancer | Marburg virus | NA | NA | GFP assay | Decrease (50 %) | NA | 25986249 |
DrugRepV_3739 | Falnidamol dihydrochloride | NA | Solid Tumor | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3740 | Falnidamol dihydrochloride | NA | Solid Tumor | Marburg virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3743 | OSU-03012 | Anticancer | Brain cancer | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 25986249 |
DrugRepV_3744 | Falnidamol | NA | Solid Tumor | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3745 | Falnidamol | NA | Solid Tumor | Ebola virus | 1976 | NA | Firefly luciferase assay | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3746 | Falnidamol | NA | Solid Tumor | Ebola virus | 2014 | NA | Firefly luciferase assay | Decrease (50 %) | Investigational | 25986249 |
DrugRepV_3748 | Amiodarone Hydrochloride | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | 1976 | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 25986249 |
DrugRepV_3749 | Amiodarone Hydrochloride | Cardiovascular agents | Anginal and Arrhythmia | Ebola virus | 2014 | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 25986249 |
DrugRepV_3751 | MLS000078751 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3752 | MLS000394177 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3753 | MLS000534476 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3754 | MLS000554255 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3755 | MLS000555232 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3756 | MLS000730532 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3757 | MLS000733230 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3758 | MLS000762907 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3759 | MLS001101371 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3760 | MLS000078751 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3761 | MLS000394177 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3762 | MLS000534476 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3763 | MLS000554255 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3764 | MLS000555232 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3765 | MLS000730532 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3766 | MLS000733230 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3767 | MLS000762907 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3768 | MLS001101371 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3769 | MLS001239325 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3770 | MLS001239325 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3771 | MLS001030162 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3772 | MLS001030162 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3773 | MLS000666802 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3774 | MLS000666802 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3775 | MLS000999960 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3776 | MLS000999960 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3777 | MLS001173370 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3778 | MLS001173370 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3779 | MLS001174896 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3780 | MLS001174896 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3781 | MLS001196083 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3782 | MLS001196083 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3783 | MLS001239358 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3784 | MLS001239358 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3785 | MLS001177927 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3786 | MLS001177927 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3787 | MLS001209453 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3788 | MLS001209453 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3789 | MLS000580080 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3790 | MLS000580080 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3791 | MLS000106706 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3792 | MLS000106706 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3793 | MLS001175455 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3794 | MLS001175455 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3795 | MLS000772389 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3796 | MLS000772389 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3797 | MLS000042810 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3798 | MLS000042810 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3799 | MLS001162808 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3800 | MLS001162808 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3801 | MLS000684231 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3802 | MLS000684231 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3803 | MLS000556387 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3804 | MLS000556387 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3805 | MLS001179278 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3806 | MLS001179278 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3807 | MLS000567464 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3808 | MLS000567464 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3809 | MLS000583959 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3810 | MLS000583959 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3811 | MLS001018888 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3812 | MLS001018888 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3813 | MLS001047402 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3814 | MLS001047402 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3815 | MLS001029946 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3816 | MLS001029946 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3817 | MLS000332573 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3818 | MLS000332573 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3819 | MLS000936259 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3820 | MLS000936259 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3821 | MLS000718690 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3822 | MLS000718690 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3823 | MLS000880330 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3824 | MLS000880330 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3825 | MLS001207131 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3826 | MLS001207131 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3827 | MLS000673118 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3828 | MLS000673118 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3829 | MLS000689481 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3830 | MLS000689481 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3831 | MLS001179272 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3832 | MLS001179272 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3833 | MLS002702500 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3834 | MLS002702500 | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3835 | MLS001180408 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3836 | MLS000737975 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3837 | MLS001237534 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3838 | MLS000336293 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3839 | MLS000780111 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3840 | MLS001179997 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3841 | MLS000418057 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3842 | MLS000936795 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3843 | MLS000092187 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3844 | MLS000391391 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3845 | MLS000569139 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3846 | MLS001045935 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3847 | MLS001181479 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3848 | MLS000391984 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3849 | MLS000063146 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3850 | MLS000768081 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3851 | MLS000091920 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3852 | MLS001150589 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3853 | MLS000736237 | NA | NA | Marburg virus | Musoke | NA | NA | Decrease (50 %) | NA | 27161622 |
DrugRepV_3854 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | Approved | 27490565 |
DrugRepV_3855 | Enclomiphene | NA | Male hypogonadism | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | Investigational | 27490565 |
DrugRepV_3856 | Zuclomiphene | NA | NA | Ebola virus | Mayinga | NA | NA | Decrease (50 %) | NA | 27490565 |
DrugRepV_3857 | Clomiphene | Genito Urinary System and Sex Hormones | Polycystic ovary syndrome | Ebola virus | Mayinga | NA | Renilla luciferase assay | Decrease (100 %) | Approved | 27490565 |
DrugRepV_3858 | Enclomiphene | NA | Male hypogonadism | Ebola virus | Mayinga | NA | Renilla luciferase assay | Decrease (100 %) | Investigational | 27490565 |
DrugRepV_3859 | Zuclomiphene | NA | NA | Ebola virus | Mayinga | NA | Renilla luciferase assay | Decrease (100 %) | NA | 27490565 |
DrugRepV_3860 | Favipiravir | Antiviral | Influenza virus | Marburg virus | Leiden | NA | RT-PCR | Decrease (50 %) | Investigational | 27736754 |
DrugRepV_3865 | Favipiravir | Antiviral | Influenza virus | Ebola virus | Mayinga 1976 | NA | MTT assay | Decrease (50 %) | Investigational | 27736754 |
DrugRepV_3866 | Favipiravir | Antiviral | Influenza virus | Ebola virus | Kikwit 1995/E718 | NA | NA | Decrease (50 %) | Investigational | 27736754 |
DrugRepV_3883 | UV-1 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3884 | UV-2 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3885 | UV-3 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3886 | UV-4 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3887 | UV-5 | NA | NA | Ebola virus | Zaire-Kikwit | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3888 | UV-1 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3889 | UV-2 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3890 | UV-3 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3891 | UV-4 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3892 | UV-5 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (50 %) | NA | 27908828 |
DrugRepV_3893 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3894 | cp15 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3895 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3896 | cp15 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3897 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3898 | cp19 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3899 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3900 | cp19 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3901 | cp3 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3902 | cp5 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3903 | cp11 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3904 | cp13 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3905 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3906 | cp16 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3907 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3908 | cp3 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3909 | cp5 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3910 | cp11 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3911 | cp13 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3912 | cp15 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3913 | cp16 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3914 | cp19 | NA | NA | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3915 | cp3 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3916 | cp5 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3917 | cp11 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3918 | cp13 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3919 | cp15 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3920 | cp16 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3921 | cp19 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3922 | CBS1129 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3923 | CBS1130 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3924 | CBS1131 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3925 | CBS1132 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3926 | CBS1133 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3927 | CBS1134 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3928 | CBS1135 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3929 | CBS1136 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3930 | CBS1137 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3931 | CBS1138 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3932 | CBS1139 | NA | NA | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | NA | 28645623 |
DrugRepV_3934 | IHVR-19029 | NA | NA | Ebola virus | NA | NA | Immunolabeling assay | Decrease (50 %) | NA | 29253498 |
DrugRepV_3935 | Favipiravir | Antiviral | Influenza virus | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | Investigational | 29289664 |
DrugRepV_3936 | Favipiravir | Antiviral | Influenza virus | Ebola virus | Makona | NA | NA | Decrease (50 %) | Investigational | 29289664 |
DrugRepV_3937 | Favipiravir | Antiviral | Influenza virus | Marburg virus | Ci67 | NA | NA | Decrease (50 %) | Investigational | 29289664 |
DrugRepV_3938 | GSK983 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3939 | Angelicin | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3940 | Benzoquinoline | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3941 | SW539 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3942 | SW320 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3943 | SW351 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3944 | SW491 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3945 | SW490 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3946 | SW388 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3947 | SW386 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3948 | SW349 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3949 | SW991 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3950 | SW456 | NA | NA | Ebola virus | NA | NA | Plaque assay | Decrease (50 %) | NA | 29294299 |
DrugRepV_3951 | Favipiravir | Antiviral | Influenza virus | Marburg virus | NA | NA | qRT-PCR | Decrease (50 %) | Investigational | 29369776 |
DrugRepV_3952 | Favipiravir | Antiviral | Influenza virus | Marburg virus | NA | NA | qRT-PCR | Decrease | Investigational | 29369776 |
DrugRepV_3953 | 12N-p-dichlorobenzyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3954 | 12N-o-methylbenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3955 | 12N-2,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3956 | 12N-3,5 -dichlorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3957 | 12N-3,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3958 | 12N-m-methoxybenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3959 | 12N-benzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3960 | 12N-p-trifluoromethoxylbenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3961 | 12N-p-fluorobenzyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3962 | 12N-3,5-dichlorobenzoyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3963 | 12N-p-chlorobenzoyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3964 | 12N-3,4-dichlorobenzoyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3965 | 12N-3,4-dichlorobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3966 | 12N-3,5-dichlorobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3967 | 12N-o-thiophenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3968 | 12N-m-cyanobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3969 | 12N-p-chlorobenzenesulfonyl aloperine | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3970 | 12N-p-chlorophenylethyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3971 | 12N-3,4-dichlorophenylethyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3972 | 12N-3,5-dichlorophenylethyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3973 | 12N-3,4-dichlorohydrocinnamyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3974 | 12N-3,5-dichlorohydrocinnamyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3975 | 12N-p-chlorohydrocinnamyl aloperine dihydrochloride | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3976 | 12N-p-dichlorobenzyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3977 | 12N-o-methylbenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3978 | 12N-2,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3979 | 12N-3,5 -dichlorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3980 | 12N-3,4-dichlorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3981 | 12N-m-methoxybenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3982 | 12N-benzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3983 | 12N-p-trifluoromethoxylbenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3984 | 12N-p-fluorobenzyl aloperine dihydrochloride | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3985 | 12N-3,5-dichlorobenzoyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3986 | 12N-p-chlorobenzoyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3987 | 12N-3,4-dichlorobenzoyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3988 | 12N-3,4-dichlorobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3989 | 12N-3,5-dichlorobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3990 | 12N-o-thiophenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3991 | 12N-m-cyanobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3992 | 12N-p-chlorobenzenesulfonyl aloperine | NA | NA | Marburg virus | NA | NA | NA | Decrease (50 %) | NA | 29494844 |
DrugRepV_3994 | Genistein | Antihelmintic | Prostate cancer | Marburg virus | NA | NA | Luciferase assay | Decrease (75 %) | Investigational | 21947546 |
DrugRepV_3995 | Genistein | Antihelmintic | Prostate cancer | Ebola virus | NA | NA | Luciferase assay | Decrease (87 %) | Investigational | 21947546 |
DrugRepV_3997 | Tyrphostin AG1478 | NA | NA | Marburg virus | NA | NA | Luciferase assay | Decrease (100 %) | NA | 21947546 |
DrugRepV_3998 | Tyrphostin AG1478 | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (100 %) | NA | 21947546 |
DrugRepV_4000 | Genistein-Tyrphostin AG1478 | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (99 %) | NA | 21947546 |
DrugRepV_4001 | FGI-103 | NA | NA | Ebola virus | Zaire | NA | Plaque assay | Decrease (50 %) | NA | 20211898 |
DrugRepV_4002 | FGI-103 | NA | NA | Ebola virus | Sudan | NA | Plaque assay | Decrease (50 %) | NA | 20211898 |
DrugRepV_4003 | FGI-103 | NA | NA | Marburg virus | Ravn | NA | Plaque assay | Decrease (50 %) | NA | 20211898 |
DrugRepV_4004 | FGI-103 | NA | NA | Marburg virus | Ci67 | NA | Plaque assay | Decrease (95 %) | NA | 20211898 |
DrugRepV_4005 | FGI-103 | NA | NA | Ebola virus | Zaire | NA | NA | Decrease | NA | 20211898 |
DrugRepV_4088 | Bafilomycin A1 | Antibiotics | NA | Ebola virus | Mayinga | NA | Inhibition assay | Decrease (50 %) | Experimental | 26069727 |
DrugRepV_4089 | Bafilomycin A1 | Antibiotics | NA | Ebola virus | Bundibugyo | NA | Inhibition assay | Decrease (50 %) | Experimental | 26069727 |
DrugRepV_4090 | Bafilomycin A1 | Antibiotics | NA | Marburg virus | Lake Victoria isolate | NA | Inhibition assay | Decrease (50 %) | Experimental | 26069727 |
DrugRepV_4092 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Mayinga | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4093 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Bundibugyo | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4094 | Chloroquine | Malaria | Malaria | Marburg virus | Lake Victoria isolate | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4096 | Omeprazole | Alimentary Tract and Metabolism | Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD | Ebola virus | Bundibugyo | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4097 | Omeprazole | Alimentary Tract and Metabolism | Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD | Marburg virus | Lake Victoria isolate | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4099 | Esomeprazole | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Ebola virus | Mayinga | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4100 | Esomeprazole | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Ebola virus | Bundibugyo | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4101 | Esomeprazole | Alimentary Tract and Metabolism | Acid-reflux disorders (GERD) and peptic ulcer disease | Marburg virus | Lake Victoria isolate | NA | Inhibition assay | Decrease (50 %) | Approved | 26069727 |
DrugRepV_4302 | Carbocyclic adenosine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4303 | Carbocyclic 3-deazaadenosine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4304 | 9-[trans- 2,trans - 3 - dihydroxy - 4 - (methyl) - cyclopent - 4 - enyl] - 3 - deazaadenine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4305 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-adenine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4306 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-3-deazaadenine | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4307 | 9-[trans-2,trans-3-dihydroxycyclopent-4-enyl]- adenine (DHCpAdo) | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4308 | 9-[trans-2,trans-3-dihydroxycyclopent- 4-enyl]-3-deazaadenine (DHCp-c3Ado) | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4309 | 4,5- didehydro-5-deoxy-5-fluoroadenosine (DDFA) | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4310 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | Approved | 9988190 |
DrugRepV_4311 | Guanosine Dialdehyde | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4312 | Adenosine Dialdehyde | NA | NA | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | Approved, Investigational | 9988190 |
DrugRepV_4313 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | Approved | 9988190 |
DrugRepV_4314 | Carbocyclic 3-deazaadenosine | NA | NA | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4315 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-adenine | NA | NA | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4316 | 9-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-3-deazaadenine | NA | NA | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | NA | 9988190 |
DrugRepV_4317 | Carbocyclic 3-deazaadenosine | NA | NA | Ebola virus | EBO-Z | NA | Survival assay | Increase | NA | 9988190 |
DrugRepV_4318 | FGI-106 | NA | NA | Ebola virus | Zaire | NA | Plaque assay | Decrease (50 %) | NA | 19523489 |
DrugRepV_4320 | FGI-106 | NA | NA | Ebola virus | Zaire | NA | Survival assay | Increase | NA | 19523489 |
DrugRepV_4321 | N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (44.6 %) | NA | 24501399 |
DrugRepV_4322 | N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (32.6 %) | NA | 24501399 |
DrugRepV_4323 | 9H-carbazol-3-amine | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (6.1 %) | NA | 24501399 |
DrugRepV_4324 | 7-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-3.8 %) | NA | 24501399 |
DrugRepV_4325 | N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-16 %) | NA | 24501399 |
DrugRepV_4326 | tris[4-(dimethylamino)phenyl]methanol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (31.8 %) | NA | 24501399 |
DrugRepV_4327 | 6-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (31.8 %) | NA | 24501399 |
DrugRepV_4328 | 1-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-1.6 %) | NA | 24501399 |
DrugRepV_4329 | 2-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-1.8 %) | NA | 24501399 |
DrugRepV_4330 | N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (66.3 %) | NA | 24501399 |
DrugRepV_4331 | 4-{[(5-methyl-2-thienyl)methyl]amino}phenol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-12.6 %) | NA | 24501399 |
DrugRepV_4332 | N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-3.4 %) | NA | 24501399 |
DrugRepV_4333 | N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.2 %) | NA | 24501399 |
DrugRepV_4334 | 2-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (8.6 %) | NA | 24501399 |
DrugRepV_4335 | N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (66.9 %) | NA | 24501399 |
DrugRepV_4336 | N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (9.6 %) | NA | 24501399 |
DrugRepV_4337 | 4-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (34 %) | NA | 24501399 |
DrugRepV_4338 | N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (11.6 %) | NA | 24501399 |
DrugRepV_4339 | N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (45.7 %) | NA | 24501399 |
DrugRepV_4340 | N-(3-chlorophenyl)-N-(4-cyanophenyl)urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.1 %) | NA | 24501399 |
DrugRepV_4341 | N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-3.4 %) | NA | 24501399 |
DrugRepV_4342 | N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (5.7 %) | NA | 24501399 |
DrugRepV_4343 | 4,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-24.6 %) | NA | 24501399 |
DrugRepV_4344 | 1-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (13.1 %) | NA | 24501399 |
DrugRepV_4345 | 2-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (6.4 %) | NA | 24501399 |
DrugRepV_4346 | N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (6.2 %) | NA | 24501399 |
DrugRepV_4347 | 2-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.7 %) | NA | 24501399 |
DrugRepV_4348 | N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (2.1 %) | NA | 24501399 |
DrugRepV_4349 | 4,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-0.6 %) | NA | 24501399 |
DrugRepV_4350 | N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-2.6 %) | NA | 24501399 |
DrugRepV_4351 | 3-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-6.1 %) | NA | 24501399 |
DrugRepV_4352 | methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (82.4 %) | NA | 24501399 |
DrugRepV_4353 | N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (33.4 %) | NA | 24501399 |
DrugRepV_4354 | N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (25.4 %) | NA | 24501399 |
DrugRepV_4355 | (1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (10.5 %) | NA | 24501399 |
DrugRepV_4356 | 4-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (25.2 %) | NA | 24501399 |
DrugRepV_4357 | N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (17.4 %) | NA | 24501399 |
DrugRepV_4358 | 3-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (26.8 %) | NA | 24501399 |
DrugRepV_4359 | 5-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-6.6 %) | NA | 24501399 |
DrugRepV_4360 | 6-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (20.9 %) | NA | 24501399 |
DrugRepV_4361 | 2-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-12.1 %) | NA | 24501399 |
DrugRepV_4362 | N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (12.3 %) | NA | 24501399 |
DrugRepV_4363 | 4-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (1.8 %) | NA | 24501399 |
DrugRepV_4364 | 2-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (1.1 %) | NA | 24501399 |
DrugRepV_4365 | 5-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-0.3 %) | NA | 24501399 |
DrugRepV_4366 | 2-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-1.5 %) | NA | 24501399 |
DrugRepV_4367 | 2-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-15.9 %) | NA | 24501399 |
DrugRepV_4368 | N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-11.5 %) | NA | 24501399 |
DrugRepV_4369 | 8-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (-11.7 %) | NA | 24501399 |
DrugRepV_4370 | N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide | NA | NA | Ebola virus | GP, amino acids 196 to 205 | NA | CatL-Peptide cleavage | Decrease (8.05 %) | NA | 24501399 |
DrugRepV_4471 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-GFP | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4472 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-Gluc | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4473 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-GFP | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4474 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-GFP | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4475 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-GFP | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4476 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-GFP | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4477 | Brincidofovir | Antiviral | Viral infections | Ebola virus | EBOV-GFP | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4478 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Mayinga | NA | Operetta High Content Imaging System | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4479 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Makona | NA | NA | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4480 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Ebola Zaire Kikwit | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4481 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Ebola Zaire Kikwit | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4482 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Ebola Zaire Kikwit | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4483 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Ebola Zaire Makona | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4484 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Ebola Zaire Makona | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4485 | Brincidofovir | Antiviral | Viral infections | Ebola virus | Ebola Zaire Makona | NA | Immunoflourescence assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4486 | Brincidofovir | NA | Viral infections | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | Investigational | 26526586 |
DrugRepV_4487 | CMX029 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4488 | CMX021 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4489 | CMX028 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4490 | CMX16669 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4491 | CMX16663 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4492 | CMX167 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4493 | CMX157 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4494 | CMX101 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4495 | CMX004 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4496 | CMX16689 | NA | NA | Ebola virus | EBOV-GFP | NA | Luciferase assay | Decrease (50 %) | NA | 26526586 |
DrugRepV_4497 | Ranpirnase | Anticancer | Cancer | Ebola virus | Kikwit | NA | NA | Decrease (50 %) | Investigational | 27350309 |
DrugRepV_4498 | Ranpirnase | Anticancer | Cancer | Ebola virus | Kikwit | NA | Fluorescence-based assay | Decrease | Investigational | 27350309 |
DrugRepV_4499 | Ranpirnase | Anticancer | Cancer | Ebola virus | Kikwit | NA | NA | Increase | Investigational | 27350309 |
DrugRepV_4500 | (1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4501 | (1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4502 | (1S,2R,5R)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4503 | (1R,2S,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4504 | (1R,2S,5R)-3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | Zaire | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4505 | (1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4506 | (1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4507 | (1S,2R,5R)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4508 | (1R,2S,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4509 | (1R,2S,5R)-3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4510 | (1S,2R,5S)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol | NA | NA | Ebola virus | NA | NA | NA | Decrease (50 %) | NA | 30385162 |
DrugRepV_4512 | Favipiravir | Antiviral | Influenza virus | Ebola virus | NA | NA | NA | Increase | Investigational | 30275474 |
DrugRepV_4513 | Remdesivir | Antiviral | Hepatitis C | Ebola | Ebola virus | NA | NA | NA | Increase | Experimental | 30275474 |
DrugRepV_4514 | Favipiravir | Antiviral | Influenza virus | Ebola virus | NA | NA | NA | Increase | Investigational | 29584730 |
DrugRepV_4822 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4823 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4824 | Dalbavancin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4825 | Oritavancin | Antiinfectives For Systemic Use | Acute bacterial skin | Skin structure infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4826 | Telavancin | Antiinfectives For Systemic Use | Skin infections (Bacterial) | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4827 | Vancomycin | Alimentary Tract and Metabolism; Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4828 | CTSL inhibitor | NA | NA | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | NA | 26953343 |
DrugRepV_5192 | C795-0925 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5193 | D011-2120 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5194 | F694-1532 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5195 | G202-0362 | NA | NA | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5196 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5197 | C795-0925 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5198 | D011-2120 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5199 | F694-1532 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5200 | G202-0362 | NA | NA | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | NA | 25144302 |
DrugRepV_5201 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5327 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5328 | diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5329 | diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5330 | 1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5331 | 2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5332 | 1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5333 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5334 | {2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5335 | 4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5336 | 4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5337 | 4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5338 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5339 | 4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5340 | 4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5341 | 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5342 | 1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5343 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5344 | 1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide | NA | NA | Ebola virus | NA | NA | Real-time PCR | Decrease (50 %) | NA | 15451189 |
DrugRepV_5349 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5350 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5351 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5352 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | NA | 21616094 |
DrugRepV_5357 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5358 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5359 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5360 | 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide | NA | NA | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | NA | 21616094 |
DrugRepV_5365 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Approved | 21616094 |
DrugRepV_5366 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Approved | 21616094 |
DrugRepV_5367 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Approved | 21616094 |
DrugRepV_5368 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (50 %) | Approved | 21616094 |
DrugRepV_5373 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | Approved | 21616094 |
DrugRepV_5374 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | Approved | 21616094 |
DrugRepV_5375 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | Approved | 21616094 |
DrugRepV_5376 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Ebola virus | NA | NA | RT-PCR | Decrease (90 %) | Approved | 21616094 |
DrugRepV_5383 | 8-Azaadenosine | NA | NA | Ebola virus | Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2014 | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5384 | Toyocamycin | NA | NA | Ebola virus | Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2015 | NA | Minigenome assays | Decrease (50 %) | Experimental | 27771389 |
DrugRepV_5385 | 6-Azauridine | NA | Cancer | Ebola virus | Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2016 | NA | Minigenome assays | Decrease (50 %) | NA | 27771389 |
DrugRepV_5386 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | NA | NA | qRT-PCR | Decrease | Investigational | 31307979 |
DrugRepV_5388 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | NA | NA | NA | Decrease (50 %) | Investigational | 31307979 |
DrugRepV_5394 | Zoniporide | NA | NA | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | NA | 30700611 |
DrugRepV_5396 | Amodiaquine | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5398 | Niclosamide | Antiparasitic products, Insectisides and Repellents | Tapeworm and intestinal fluke infections | Helminthiasis | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5400 | Apilimod | NA | Crohn's disease | Psoriasis | Psoriatic disorders | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Investigational | 30700611 |
DrugRepV_5402 | Arbidol | NA | Viral infection | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Investigational | 30700611 |
DrugRepV_5404 | Clomiphene | Genito Urinary System and Sex Hormones | Female infertility | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5406 | Sertraline | Nervous System | Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved | 30700611 |
DrugRepV_5408 | Toremifene | Antineoplastic and Immunomodulating Agents | Breast Cancer | Ebola virus | Mayinga | NA | Luciferase assay | Decrease (50 %) | Approved, Investigational | 30700611 |
DrugRepV_5491 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5492 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5493 | Amodiaquine Dihydrochloride Dihydrate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5494 | Artesunate | Antiparasitic products, Insectisides and Repellents | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Approved, Investigational | 31882748 |
DrugRepV_5495 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5496 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5497 | Winthrop | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5498 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5499 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5500 | N-Desethylamodiaquine hydrochloride | NA | NA | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | NA | 31882748 |
DrugRepV_5501 | Dihydroartimesinin | NA | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Experimental, Investigational | 31882748 |
DrugRepV_5502 | Dihydroartimesinin | NA | Malaria | Ebola virus | NA | NA | Cell based assay | Decrease (50 %) | Experimental, Investigational | 31882748 |
DrugRepV_8294 | Tolcapone | Nervous System | Parkinson's Disease | Ebola virus | NA | NA | NA | Decrease (50 %) | Approved, Withdrawn | 32425892 |
DrugRepV_8295 | Tolcapone | Nervous System | Parkinson's Disease | Ebola virus | NA | NA | NA | Decrease (50 %) | Approved, Withdrawn | 32425892 |
DrugRepV_8296 | Tolcapone | Nervous System | Parkinson's Disease | Ebola virus | NA | NA | NA | Decrease (50 %) | Approved, Withdrawn | 32425892 |
DrugRepV_8297 | Tolcapone | Nervous System | Parkinson's Disease | Ebola virus | NA | NA | NA | Decrease (50 %) | Approved, Withdrawn | 32425892 |