DrugRepV Browse Page


DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for Filoviridae are 1054




DrugRepV_ID Antiviral Name
Drug type
Primary Indication
Secondary Indication
Strain
Pathways
Assay
Activity
Clinical Status
References
DrugRepV_0068Sunitinib
Antineoplastic and Immunomodulating Agents
Renal cell carcinoma | Gastrointestinal stromal tumor
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
28240606
DrugRepV_0069Erlotinib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
Approved
28240606
DrugRepV_0070Erlotinib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
Approved
28240606
DrugRepV_0073Sunitinib-Erlotinib
NA
NA
Ebola virus
rVSV-GP EBOV
NA
Flow cytometry
Decrease
NA
28240606
DrugRepV_0074Sunitinib-Erlotinib
NA
NA
Ebola virus
Mouse adapted strain
NA
NA
Increase
NA
28240606
DrugRepV_0198Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27890675
DrugRepV_0199Chloroquine
Antiparasitic products, Insectisides and Repellents
malaria
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27890675
DrugRepV_0200Maprotiline
Nervous System
Bipolar depression
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27890675
DrugRepV_0201Mefloquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27890675
DrugRepV_0202Azithromycin
Antiinfectives For Systemic Use
Microbial infections
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27890675
DrugRepV_0203Clarithromycin
Antiinfectives For Systemic Use
Microbial infections
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27890675
DrugRepV_0204Posaconazole
Antiinfectives For Systemic Use
Fungal infections (Aspergillus and Candida infections)
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational, Vet approved
27890675
DrugRepV_0205Toremifene-Clarithromycin-Posaconazole
NA
NA
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
NA
27890675
DrugRepV_0206Toremifene-Mefloquine-Posaconazole
NA
NA
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
NA
27890675
DrugRepV_0207Chloroquine-Maprotiline-Azithromycin
NA
Malaria and Depression
Ebola virus
VLP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27890675
DrugRepV_0208Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27890675
DrugRepV_0209Posaconazole
Antiinfectives For Systemic Use
Fungal infections (Aspergillus and Candida infections)
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational, Vet approved
27890675
DrugRepV_0210Mefloquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27890675
DrugRepV_0211Clarithromycin
Antiinfectives For Systemic Use
Microbial infections
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27890675
DrugRepV_0212Maprotiline
Nervous System
Bipolar depression
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27890675
DrugRepV_0213Toremifene-Clarithromycin-Posaconazole
NA
NA
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (>90 %)
NA
27890675
DrugRepV_0214Toremifene-Mefloquine-Posaconazole
NA
NA
Ebola virus
EBOLA/Mayinga-eGFP
NA
Immunoflourescence assay
Decrease (74 %)
NA
27890675
DrugRepV_0215Ouabain
Cardiovascular agents
Atrial fibrillation and flutter | Heart failure
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (3.48 ± 0.21 Ct)
Approved
27801778
DrugRepV_0216Ouabain
Cardiovascular agents
Atrial fibrillation and flutter | Heart failure
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?3.73 ± 4.88 Ct)
Approved
27801778
DrugRepV_0217Alvespimycin
NA
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (3.72 ± 0.18 Ct)
Investigational
27801778
DrugRepV_0218Alvespimycin
NA
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?0.63 ± 1.39 Ct)
Investigational
27801778
DrugRepV_0219Bemcentinib
Anticancer
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (3.05 ± 0.75 Ct)
Investigational
27801778
DrugRepV_0220Bemcentinib
Anticancer
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?1.83 ± 1.13 Ct)
Investigational
27801778
DrugRepV_0221Zidovudine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome/AIDS
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?3.12 ± 0.27 Ct)
Approved
27801778
DrugRepV_0222Zidovudine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome/AIDS
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?7.91 ± 2.67 Ct)
Approved
27801778
DrugRepV_0223Didanosine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?0.43 ± 3.87 Ct)
Approved
27801778
DrugRepV_0224Didanosine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?2.52 ± 1.27 Ct)
Approved
27801778
DrugRepV_0225Stavudine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?2.87 ± 0.22 Ct)
Approved, Investigational
27801778
DrugRepV_0226Stavudine
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?3.93 ± 0.25 Ct)
Approved, Investigational
27801778
DrugRepV_0227Abacavir Sulfate
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?1.54 ± 3.26 Ct)
Approved
27801778
DrugRepV_0228Abacavir Sulfate
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?3.95 ± 2.69 Ct)
Approved
27801778
DrugRepV_0229Entecavir
Antiinfectives For Systemic Use
Hepatitis B virus
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?3.08 ± 0.20 Ct)
Approved
27801778
DrugRepV_0230Entecavir
Antiinfectives For Systemic Use
Hepatitis B virus
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?4.44 ± 1.11 Ct)
Approved
27801778
DrugRepV_0231JB1a
NA
NA
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?4.02 ± 0.13 Ct)
NA
27801778
DrugRepV_0232JB1a
NA
NA
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?5.48 ± 0.50 Ct)
NA
27801778
DrugRepV_0233Omeprazole
Alimentary Tract and Metabolism
Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (1.35 ± 1.35 Ct)
Approved
27801778
DrugRepV_0234Omeprazole
Alimentary Tract and Metabolism
Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (2.21 ± 1.08 Ct)
Approved
27801778
DrugRepV_0235Esomeprazole Magnesium
Alimentary Tract and Metabolism
Acid-reflux disorders (GERD) and peptic ulcer disease
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (1.05 ± 0.79 Ct)
Approved
27801778
DrugRepV_0236Esomeprazole Magnesium
Alimentary Tract and Metabolism
Acid-reflux disorders (GERD) and peptic ulcer disease
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (1.62 ± 0.36 Ct)
Approved
27801778
DrugRepV_0237Gleevec
Antineoplastic and Immunomodulating Agents
Leukemia
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (3.60 ± 0.63 Ct)
Approved
27801778
DrugRepV_0238Gleevec
Antineoplastic and Immunomodulating Agents
Leukemia
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (3.49 ± 0.54 Ct)
Approved
27801778
DrugRepV_0239Aimspro
NA
Multiple sclerosis
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?2.03 ± 0.95 Ct)
Phase II
27801778
DrugRepV_0240Aimspro
NA
Multiple sclerosis
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?4.60 ± 1.15 Ct)
Phase II
27801778
DrugRepV_0241NCK-8
NA
NA
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (>10 Ct)
NA
27801778
DrugRepV_0242NCK-8
NA
NA
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (>10 Ct)
NA
27801778
DrugRepV_0243D-LANA-14
Antibacterial
Bacterial infections
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (>10 Ct)
NA
27801778
DrugRepV_0244D-LANA-14
Antibacterial
Bacterial infections
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (>10 Ct)
NA
27801778
DrugRepV_0245Tasigna
Antineoplastic and Immunomodulating Agents
Myeloid leukemia
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (3.59 ± 0.57 Ct)
Approved, Investigational
27801778
DrugRepV_0246Tasigna
Antineoplastic and Immunomodulating Agents
Myeloid leukemia
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?0.13 ± 0.33 Ct)
Approved, Investigational
27801778
DrugRepV_0247Celgosivir
Antiviral
Hepatitis C virus
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?2.52 ± 0.21 Ct)
Investigational
27801778
DrugRepV_0248Celgosivir
Antiviral
Hepatitis C virus
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?2.41 ± 0.12 Ct)
Investigational
27801778
DrugRepV_0249Castanospermine
Antiviral
Dengue and Parainfluenza
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?1.58 ± 3.23 Ct)
Experimental
27801778
DrugRepV_0250Castanospermine
Antiviral
Dengue and Parainfluenza
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Increase (?0.26 ± 4.11 Ct)
Experimental
27801778
DrugRepV_0251Ouabain
Cardiovascular agents
Atrial fibrillation and flutter | Heart failure
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (0.33 ± 0.35 Ct)
Approved
27801778
DrugRepV_0252Alvespimycin
NA
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (0.44 ± 0.06 Ct)
Investigational
27801778
DrugRepV_0253Bemcentinib
Anticancer
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (0.90 ± 0.15 Ct)
Investigational
27801778
DrugRepV_0254Omeprazole
Alimentary Tract and Metabolism
Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (0.86 ± 0.22 Ct)
Approved
27801778
DrugRepV_0255Esomeprazole
Alimentary Tract and Metabolism
Acid-reflux disorders (GERD) and peptic ulcer disease
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (0.78 ± 0.25 Ct)
Approved
27801778
DrugRepV_0256Gleevec
Antineoplastic and Immunomodulating Agents
Leukemia
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (1.55 ± 0.20 Ct)
Approved
27801778
DrugRepV_0257NCK-8
NA
NA
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (1.54 ± 0.44 Ct)
NA
27801778
DrugRepV_0258D-LANA-14
Antibacterial
Bacterial infections
Ebola virus
ME718-1976/Yambuku-Ecran
NA
Real-time PCR
Decrease (0.96 ± 0.19 Ct)
NA
27801778
DrugRepV_0259Alvespimycin
NA
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
NA
No significant effect
Investigational
27801778
DrugRepV_0260Bemcentinib
Anticancer
Cancer
Ebola virus
ME718-1976/Yambuku-Ecran
NA
NA
No significant effect
Investigational
27801778
DrugRepV_0261NCK-8
NA
NA
Ebola virus
ME718-1976/Yambuku-Ecran
NA
NA
No significant effect
NA
27801778
DrugRepV_0317Niclosamide
Antiparasitic products, Insectisides and Repellents
Tapeworm and intestinal fluke infections | Helminthiasis
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational, Vet approved
27622822
DrugRepV_0318Mebendazole
Antiparasitic products, Insectisides and Repellents
Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections)
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Vet approved
27622822
DrugRepV_0319Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0320Procainamide
Cardiovascular agents
Ventricular arrhythmias
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0321Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0322Chlortetracycline
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0323Clemastine
Respiratory System
Sneezing, rhinorrhea, pruritus and acrimation
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0324Benztropine
Nervous System
Parkinson disease
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0325Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0326Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0327Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0328Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0329Vincristine
Antineoplastic and Immunomodulating Agents
Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors)
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0330Thiothixene
Nervous System
Schizophrenia
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0331Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Vet approved
27622822
DrugRepV_0332Fluphenazine
Nervous System
Psychosis
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0333Perphenazine
Nervous System
Psychosis | Nausea and vomiting in adults
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0334Promazine
Nervous System
Psychomotor agitation
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Vet approved
27622822
DrugRepV_0335Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved, Investigational
27622822
DrugRepV_0336Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0337Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
EBOV-eGFP
NA
Immunoflourescence assay
Decrease (50 %)
Approved
27622822
DrugRepV_0338Niclosamide
Antiparasitic products, Insectisides and Repellents
Tapeworm and intestinal fluke infections | Helminthiasis
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0339Mebendazole
Antiparasitic products, Insectisides and Repellents
Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections)
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved, Vet approved
27622822
DrugRepV_0340Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0341Procainamide
Cardiovascular agents
Ventricular arrhythmias
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0342Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0343Chlortetracycline
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0344Benztropine
Nervous System
Parkinson disease
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0345Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0346Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0347Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0348Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0349Vincristine
Antineoplastic and Immunomodulating Agents
Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors)
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0350Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0351Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved, Investigational
27622822
DrugRepV_0352Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus
NA
Renilla luciferase assay
Decrease (50 %)
Approved
27622822
DrugRepV_0353Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire
NA
Survival assay
Increase
Approved
27622822
DrugRepV_0354Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0355Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire
NA
Survival assay
Increase
Approved
27622822
DrugRepV_0356Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0357Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
Ebola Zaire
NA
Survival assay
Increase
Approved
27622822
DrugRepV_0358Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0359Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0360Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0361Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0362Benztropine
Nervous System
Parkinson disease
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0363Benztropine
Nervous System
Parkinson disease
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0364Chlortetracycline
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0365Chlortetracycline
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Zaire
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0366Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Ebola Mayinga
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0367Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Ebola Mayinga
NA
Survival assay
No significant effect
Approved
27622822
DrugRepV_0368Amlodipine Besylate
Cardiovascular agents
Hypertension and chronic stable angina
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0369Azelastine
Respiratory System
Rhinitis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0370Benztropine Mesylate
Nervous System
Parkinson disease
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0371Cephapirin Sodium
Antibiotics
Bacterial infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0372Chlorhexidine Diacetate
Alimentary Tract and Metabolism
Disinfectant, oropharyngeal decontamination
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0373Ciclesonide
Respiratory System
Allergic rhinitis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0374Cilastatin Sodium
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0375Clemastine Fumarate
Respiratory System
Allergic rhinitis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0376Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0377Clomipramine Hydrochloride
Nervous System
Obsessive-compulsive disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0378Danazol
Genito Urinary System and Sex Hormones
Endometriosis and fibrocystic breast disease
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0379Deslanoside
Cardiovascular agents
Congestive cardiac insufficiency, arrhythmias and heart failure
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0380Dicyclomine Hydrochloride
Alimentary Tract and Metabolism
Bowel/irritable bowel syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0381Digitoxin
Cardiovascular agents
Cardiac insufficiency, arrhythmias and heart failure
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0382Digoxin
Cardiovascular agents
Cardiac insufficiency, arrhythmias and heart failure
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0383Doxylamine Succinate
Respiratory System
Cough, vomiting and nausea
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0384Flucytosine
Antiinfectives For Systemic Use
Fungal infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0385Fluphenazine Hydrochloride
Nervous System
Psychosis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0386Fluvastatin
Cardiovascular agents
Cardiovascular disease (Coronary heart disease (CHD))
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0387Guanethidine Monosulfate
Cardiovascular agents
Hypertension
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0388Hexachlorophene
Dermatologicals
Bacterial infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0389Hycanthone
Antischistosomal
Parasitic infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26041706
DrugRepV_0390Hydroxyprogesterone Caproate
Genito Urinary System and Sex Hormones
Spontaneous preterm births
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0391Loperamide
Alimentary Tract and Metabolism
Chronic diarrhea associated with inflammatory bowel disease or gastroenteritis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0392Maprotiline Hydrochloride
Nervous System
Bipolar depression
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0393Mebendazole
Antiparasitic products, Insectisides and Repellents
Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Vet approved
26041706
DrugRepV_0394Methdilazine Hydrochloride
Respiratory System
Hypersensitivity reactions | Skin disorders
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0395Mycophenolate Mofetil
Immunosuppressant
Organ rejection (immunosuppressants)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0396Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0397Niclosamide
Antiparasitic products, Insectisides and Repellents
Tapeworm and intestinal fluke infections | Helminthiasis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0398Nonoxynol-9
Gynaecological-agents
Contraception
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0399Paroxetine Hydrochloride Hemihydrate
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0400Pentamidine
Antiparasitic products, Insectisides and Repellents
Pneumonia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0401Perhexiline Maleate
Cardiovascular agents
Angina pectoris
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0402Perphenazine
Nervous System
Psychosis | Nausea and vomiting in adults
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0403Podofilox
Dermatologicals
External genital warts
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0404Prochlorperazine Edisylate
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Vet approved
26041706
DrugRepV_0405Pyrvinium Pamoate
Antiparasitic products, Insectisides and Repellents
Pinworm infestations
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0406Quinacrine Dihydrochloride
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Investigational
26041706
DrugRepV_0407Quinestrol
Gynaecological-agents
Hormone replacement therapy | Treating symptoms of menopause such as hot flashes | Breast cancer | Prostate cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0408Raloxifene Hydrochloride
Genito Urinary System and Sex Hormones
Osteoporosis | Corticosteroid-induced bone loss
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0409Sertraline Hydrochloride
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0410Sorafenib Tosylate
Antineoplastic and Immunomodulating Agents
Hepatocellular carcinoma | Renal cell carcinoma
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0411Sunitinib Malate
Antineoplastic and Immunomodulating Agents
Renal cell carcinoma | Gastrointestinal stromal tumor
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0412Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0413Tamoxifen Citrate
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0414Thioridazine Hydrochloride
Nervous System
Schizophrenia | Anxiety disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0415Tioconazole
Dermatologicals; Genito Urinary System and Sex Hormones
Vulvovaginal candidiasis (moniliasis)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0416Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0417Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0418Trifluoperazine Hydrochloride
Nervous System
Schizophrenia and other psychotic disorders
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0419Triflupromazine Hydrochloride
Nervous System
Psychosis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0420Vinorelbine Tartrate Hydrate
Antineoplastic and Immunomodulating Agents
Breast cancer and non-small cell lung cancer (NSCLC)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
NA
26041706
DrugRepV_0421Aripiprazole
Nervous System
Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0422Astemizole
Respiratory System
Allergies
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0423Atovaquone
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0424Azacitidine
Antineoplastic and Immunomodulating Agents
French-American-British myelodysplastic syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0425Benztropine
Nervous System
Parkinson disease
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0426Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0427Clemastine
Respiratory System
Allergic rhinitis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0428Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0429Clomipramine
Nervous System
Depression, schizophrenia, Tourette disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0430Dasatinib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0431Efavirenz
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0432Flupentixol
Nervous System
Schizophrenia | Depression
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational, Withdrawn
26041706
DrugRepV_0433Fluphenazine
Nervous System
Psychosis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0434Hycanthone
Antischistosomal
Parasitic infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26041706
DrugRepV_0435Lomerizine
Neurologic-agent
Migraine disorders
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26041706
DrugRepV_0436Maprotiline
Nervous System
Bipolar depression
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0437Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0438Pimozide
Nervous System
Tourette Disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0439Piperacetazine
Antipsychotic
Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
NA
26041706
DrugRepV_0440Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0441Quinacrine
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Investigational
26041706
DrugRepV_0442Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0443Simvastatin
Cardiovascular agents
Hypercholesterolemia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0444Strophanthin
Cardiovascular agents
Atrial fibrillation | Flutter | Heart failure
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0445Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0446Terconazole
Genito Urinary System and Sex Hormones
Candidiasis (a yeast-like fungal infection) of the vulva and vagina
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0447Thioridazine
Nervous System
Schizophrenia | Anxiety disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0448Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0449Aripiprazole
Nervous System
Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0450Astemizole
Respiratory System
Allergies
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0451Azacitidine
Antineoplastic and Immunomodulating Agents
French-American-British myelodysplastic syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0452Benztropine
Nervous System
Parkinson disease
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0453Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0454Clemastine
Respiratory System
Allergic rhinitis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0455Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0456Clomipramine
Nervous System
Depression, schizophrenia, Tourette disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0457Dasatinib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0458Efavirenz
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0459Flupentixol
Nervous System
Schizophrenia | Depression
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational, Withdrawn
26041706
DrugRepV_0460Fluphenazine
Nervous System
Psychosis
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0461Hycanthone
Antischistosomal
Parasitic infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26041706
DrugRepV_0462Lomerizine
Neurologic-agent
Migraine disorders
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26041706
DrugRepV_0463Maprotiline
Nervous System
Bipolar depression
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0464Mycophenolate Mofetil
Immunosuppressant
Organ rejection (immunosuppressants)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0465Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0466Pimozide
Nervous System
Tourette Disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0467Piperacetazine
Antipsychotic
Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
NA
26041706
DrugRepV_0468Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0469Quinacrine
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Investigational
26041706
DrugRepV_0470Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0471Strophanthin
Cardiovascular agents
Atrial fibrillation | Flutter | Heart failure
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0472Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0473Terconazole
Genito Urinary System and Sex Hormones
Candidiasis (a yeast-like fungal infection) of the vulva and vagina
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0474Thioridazine
Nervous System
Schizophrenia | Anxiety disorder
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0475Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26041706
DrugRepV_0476Vinorelbine
Antineoplastic and Immunomodulating Agents
Breast cancer and non-small cell lung cancer (NSCLC)
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0477Aripiprazole
Nervous System
Schizophrenia
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0478Astemizole
Respiratory System
Allergies
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Withdrawn
26041706
DrugRepV_0479Atovaquone
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOV-VLP
NA
Flow cytometry
No significant effect
Approved
26041706
DrugRepV_0480Azacitidine
Antineoplastic and Immunomodulating Agents
French-American-British myelodysplastic syndrome
Ebola virus
EBOV-VLP
NA
Flow cytometry
No significant effect
Approved
26041706
DrugRepV_0481Benztropine
Nervous System
Parkinson disease
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0482Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Withdrawn
26041706
DrugRepV_0483Clemastine
Respiratory System
Allergic rhinitis
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0484Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0485Clomipramine
Nervous System
Depression, schizophrenia, Tourette disorder
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0486Dasatinib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0487Efavirenz
Antiinfectives For Systemic Use
Acquired immunodeficiency syndrome
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0488Flupentixol
Nervous System
Schizophrenia | Depression
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Investigational, Withdrawn
26041706
DrugRepV_0489Fluphenazine
Nervous System
Psychosis
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0490Hycanthone
Antischistosomal
Parasitic infections
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Experimental
26041706
DrugRepV_0491Lomerizine
Neurologic-agent
Migraine disorders
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Experimental
26041706
DrugRepV_0492Maprotiline
Nervous System
Bipolar depression
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Investigational
26041706
DrugRepV_0493Mycophenolate Mofetil
Immunosuppressant
Organ rejection (immunosuppressants)
Ebola virus
EBOV-VLP
NA
Flow cytometry
No significant effect
Approved, Investigational
26041706
DrugRepV_0494Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Investigational
26041706
DrugRepV_0495Pimozide
Nervous System
Tourette Disorder
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0496Piperacetazine
Antipsychotic
Schizophrenia
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
NA
26041706
DrugRepV_0497Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0498Quinacrine
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
EBOV-VLP
NA
Flow cytometry
No significant effect
Investigational
26041706
DrugRepV_0499Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0500Simvastatin
Cardiovascular agents
Hypercholesterolemia
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0501Strophanthin
Cardiovascular agents
Atrial fibrillation | Flutter | Heart failure
Ebola virus
EBOV-VLP
NA
Flow cytometry
No significant effect
Approved
26041706
DrugRepV_0502Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0503Terconazole
Genito Urinary System and Sex Hormones
Candidiasis (a yeast-like fungal infection) of the vulva and vagina
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0504Thioridazine
Nervous System
Schizophrenia | Anxiety disorder
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Withdrawn
26041706
DrugRepV_0505Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved, Investigational
26041706
DrugRepV_0506Vinorelbine
Antineoplastic and Immunomodulating Agents
Breast cancer and non-small cell lung cancer (NSCLC)
Ebola virus
EBOV-VLP
NA
Flow cytometry
Decrease (>90 %)
Approved
26041706
DrugRepV_0507Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
ma-EBOV
NA
Survival assay
Increase
Approved, Withdrawn
26041706
DrugRepV_0508Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
ma-EBOV
NA
Survival assay
Increase
Approved
26041706
DrugRepV_0509Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
EBOV/Kik
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0510Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
SUDV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0511Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
MARV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0512Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
RAVV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Withdrawn
26041706
DrugRepV_0513Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
EBOV/Kik
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0514Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
EBOV/May
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0515Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
SUDV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0516Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
MARV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0517Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
RAVV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26041706
DrugRepV_0518Vinblastine
Antineoplastic and Immunomodulating Agents
Cancer (Hodgkin lymphoma | Non-Hodgkin's lymphoma |Testicular | Breast | Lung (Non-small cell lung cancer) | Head and neck | Bladder cancers | Melanoma | Soft tissue sarcoma |Kaposi's sarcoma | Mycosis fungoides (t-cell lymphoma) | Choriocarcinoma)
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0519Vinorelbine
Antineoplastic and Immunomodulating Agents
Breast cancer and non-small cell lung cancer (NSCLC)
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0520Vincristine
Antineoplastic and Immunomodulating Agents
Cancer (Acute leukemia |Hodgkin's and non-Hodgkin's lymphoma |Neuroblastoma |Rhabdomyosarcoma |Ewing's sarcoma |Wilms' tumor | Multiple myeloma | Chronic leukemias | Thyroid cancer | Brain tumors)
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0521Colchicine
Musculo-Skeletal System
Gout
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0522Nocodazole
Anticancer
NA
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26038505
DrugRepV_0523Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0524Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0525Digoxin
Cardiovascular agents
Cardiac insufficiency, arrhythmias and heart failure
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0526Clemastine
Respiratory System
Allergic rhinitis
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0527Raloxifene/Evista
Genito Urinary System and Sex Hormones
Osteoporosis | Corticosteroid-induced bone loss
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0528Sunitinib
Antineoplastic and Immunomodulating Agents
Renal cell carcinoma | Gastrointestinal stromal tumor
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0529Thiothixene
Nervous System
Schizophrenia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0530Dronedarone
Cardiovascular agents
Arrhythmia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0531Maprotiline
Nervous System
Bipolar depression
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0532Daunorubicin
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0533Benztropine
Nervous System
Parkinson disease
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0534Azithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0535Mebendazole
Antiparasitic products, Insectisides and Repellents
Helminthiasis (Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections)
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Vet approved
26038505
DrugRepV_0536Trifluoperazine
Nervous System
Schizophrenia and other psychotic disorders
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0537Clarithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0538Albendazole
Antiparasitic products, Insectisides and Repellents
Parasitic infections
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0539Clomipramine
Nervous System
Depressive disorder
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0540Propafenone
Cardiovascular agents
Arrhythmia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0541Carfilzomib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0542Deslanoside
Cardiovascular agents
Arrhythmia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0543Maduramicin
Antiprotozoal
Coccidiosis
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Vet approved
26038505
DrugRepV_0544Cepharanthine
Antiinflammatory and antineoplastic
Inflammatory disorders/Cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
NA
26038505
DrugRepV_0545Clomiphene
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0546Oxibendazole
Antiparasitic
Helminth intestinal infections
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Investigational, Vet approved
26038505
DrugRepV_0547Daunorubicin
Antineoplastic and Immunomodulating Agents
Microbial infections and cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0548Niclosamide
Antiparasitic products, Insectisides and Repellents
Tapeworm and intestinal fluke infections | Helminthiasis
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0549Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0550Mefloquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0551Tilorone
NA
Acquired immunodeficiency syndrome
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0552Bazedoxifene
Genito Urinary System and Sex Hormones
Postmenopausal osteoporosis
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0553Topotecan
Antineoplastic and Immunomodulating Agents
Ovarian cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0554Bosutinib
Antineoplastic and Immunomodulating Agents
Cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0555Thioproperazine
Nervous System
Psychosis | Acute and Chronic schizophrenia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0556Spiramycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0557Mibefradil
Cardiovascular agents
Angina | High blood pressure
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Investigational, Withdrawn
26038505
DrugRepV_0558Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0559Nitrovin
NA
NA
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
NA
26038505
DrugRepV_0560Bifemelane
Nervous System
Depressive disorder
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26038505
DrugRepV_0561Bitolterol
Respiratory System
Bronchodilator
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Withdrawn
26038505
DrugRepV_0562Proglumetacin
Musculo-Skeletal System
Inflammatory disorders
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Experimental
26038505
DrugRepV_0563Aprindine
Cardiovascular agents
Arrhythmia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0564Cyclomethycaine
NA
Anesthesia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Withdrawn
26038505
DrugRepV_0565Posaconazole
Antiinfectives For Systemic Use
Fungal infections (Aspergillus and Candida infections)
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational, Vet approved
26038505
DrugRepV_0566Alverine Citrate
Alimentary Tract and Metabolism
Muscle spasms
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0567Azaclorzine
NA
Anginal
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
NA
26038505
DrugRepV_0568Salmeterol
Respiratory System
Asthma | Chronic obstructive pulmonary disease
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0569Piperacetazine
Antipsychotic
Schizophrenia
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
NA
26038505
DrugRepV_0570Gefitinib
Antineoplastic and Immunomodulating Agents
Non-small cell lung cancer
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0571Imipramine
Nervous System
Depression
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0572Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved
26038505
DrugRepV_0573Nilotinib
Antineoplastic and Immunomodulating Agents
Leukemias | Chronic myeloid leukemia (CML)
Ebola virus
EBOVBlaVP40
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
26038505
DrugRepV_0581Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
23785035
DrugRepV_0582Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved
23785035
DrugRepV_0583Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0584Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
eGFP-EBOV
NA
Fluorescence-based assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0585Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
EBOV/Kik
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved
23785035
DrugRepV_0586Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
EBOV/May
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved
23785035
DrugRepV_0587Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
SUDV
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved
23785035
DrugRepV_0588Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
MARV
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved
23785035
DrugRepV_0589Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
RAVV
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved
23785035
DrugRepV_0590Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV/Kik
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0591Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV/May
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0592Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
SUDV
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0593Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
MARV
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0594Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
RAVV
NA
Enzyme-linked immunosorbent assay
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0595Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
EBOV/Kik
NA
Real-time PCR
Decrease (50 %)
Approved
23785035
DrugRepV_0596Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
SUDV
NA
Real-time PCR
Decrease (50 %)
Approved
23785035
DrugRepV_0597Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
MARV
NA
Real-time PCR
Decrease (50 %)
Approved
23785035
DrugRepV_0598Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV/Kik
NA
Real-time PCR
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0599Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
SUDV
NA
Real-time PCR
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0600Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
MARV
NA
Real-time PCR
Decrease (50 %)
Approved, Investigational
23785035
DrugRepV_0601Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
ma-EBOV
NA
NA
Increase
Approved
23785035
DrugRepV_0602Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
ma-EBOV
NA
NA
Increase
Approved, Investigational
23785035
DrugRepV_0603Clomiphene Citrate
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
VLP-GP
NA
Flow cytometry
Decrease (93 %)
Approved
23785035
DrugRepV_0604Toremifene Citrate
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
VLP-GP
NA
Flow cytometry
Decrease (95 %)
Approved, Investigational
23785035
DrugRepV_0644Amlodipine
Cardiovascular agents
Hypertension
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (93 %)
Approved
23577127
DrugRepV_0645Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (97 %)
Approved
23577127
DrugRepV_0646Biperiden
Nervous System
Parkinson disease
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (89 %)
Approved
23577127
DrugRepV_0647Carprofen
Anti-inflammatory
Joint pain
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (88 %)
Approved, Withdrawn
23577127
DrugRepV_0648Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (97 %)
Approved
23577127
DrugRepV_0649Dexbrompheniramine
Respiratory System
Allergies
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (80 %)
Approved
23577127
DrugRepV_0650Dibucaine
Nervous System
Anesthesia
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (93 %)
Approved
23577127
DrugRepV_0651Diphenoxylate
Alimentary Tract and Metabolism
Diarrhea
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (95 %)
Approved
23577127
DrugRepV_0652Diphenylpyraline
Respiratory System
Allergies
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (85 %)
Approved
23577127
DrugRepV_0653Dipivefrin
Sensory Organ
Glaucoma
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (90 %)
Approved
23577127
DrugRepV_0654Dirithromycin
Antiinfectives For Systemic Use
Bacterial infections
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (91 %)
Approved
23577127
DrugRepV_0655Erythromycin
Antiinfectives For Systemic Use
Bacterial infections
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Approved
23577127
DrugRepV_0656Estradiol
Genito Urinary System and Sex Hormones
Vulvar and vaginal atrophy
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Approved
23577127
DrugRepV_0657Fluoxetine
Nervous System
Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Approved, Vet approved
23577127
DrugRepV_0658Ketotifen
Respiratory System
Atopic asthma | Conjunctivitis
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (97 %)
Approved
23577127
DrugRepV_0659Levopropoxyphene
Respiratory-Tract-agents
Cough and associated respiratory tract disorders
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (89 %)
Withdrawn
23577127
DrugRepV_0660Mycophenolate Mofetil
Immunosuppressant
Organ rejection (immunosuppressants)
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (81 %)
Approved, Investigational
23577127
DrugRepV_0661Oxyphencyclimine
Alimentary Tract and Metabolism
Peptic ulcers
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (89 %)
Approved
23577127
DrugRepV_0662Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (89 %)
Approved, Investigational
23577127
DrugRepV_0663Penbutolol
Cardiovascular agents
Arterial hypertension
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (81 %)
Approved, Investigational
23577127
DrugRepV_0664Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (93 %)
Approved
23577127
DrugRepV_0665Protriptyline
Nervous System
Depressive disorder
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (80 %)
Approved
23577127
DrugRepV_0666Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (96 %)
Approved, Investigational
23577127
DrugRepV_0667Trihexyphenidyl
Nervous System
Parkinson Disease
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (91 %)
Approved
23577127
DrugRepV_0668Amlodipine
Cardiovascular agents
Hypertension
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (93 %)
Approved
23577127
DrugRepV_0669Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (99 %)
Approved
23577127
DrugRepV_0670Biperiden
Nervous System
Parkinson disease
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Approved
23577127
DrugRepV_0671Carprofen
Anti-inflammatory
Joint pain
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (94 %)
Approved, Withdrawn
23577127
DrugRepV_0672Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (97 %)
Approved
23577127
DrugRepV_0673Dexbrompheniramine
Respiratory System
Allergies
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (85 %)
Approved
23577127
DrugRepV_0674Dibucaine
Nervous System
Anesthesia
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (99 %)
Approved
23577127
DrugRepV_0675Diphenoxylate
Alimentary Tract and Metabolism
Diarrhea
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (96 %)
Approved
23577127
DrugRepV_0676Diphenylpyraline
Respiratory System
Allergies
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (96 %)
Approved
23577127
DrugRepV_0677Dipivefrin
Sensory Organ
Glaucoma
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (94 %)
Approved
23577127
DrugRepV_0678Dirithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (99 %)
Approved
23577127
DrugRepV_0679Erythromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (96 %)
Approved
23577127
DrugRepV_0680Estradiol
Genito Urinary System and Sex Hormones
Vulvar and vaginal atrophy
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (93 %)
Approved
23577127
DrugRepV_0681Fluoxetine
Nervous System
Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (96 %)
Approved, Vet approved
23577127
DrugRepV_0682Ketotifen
Respiratory System
Atopic asthma | Conjunctivitis
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (99 %)
Approved
23577127
DrugRepV_0683Levopropoxyphene
Respiratory-Tract-agents
Cough and associated respiratory tract disorders
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Withdrawn
23577127
DrugRepV_0684Mycophenolate Mofetil
Immunosuppressant
Organ rejection (immunosuppressants)
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (91 %)
Approved, Investigational
23577127
DrugRepV_0685Oxyphencyclimine
Alimentary Tract and Metabolism
Peptic ulcers
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (95 %)
Approved
23577127
DrugRepV_0686Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Approved, Investigational
23577127
DrugRepV_0687Penbutolol
Cardiovascular agents
Arterial hypertension
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (98 %)
Approved, Investigational
23577127
DrugRepV_0688Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (95 %)
Approved
23577127
DrugRepV_0689Protriptyline
Nervous System
Depressive disorder
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (83 %)
Approved
23577127
DrugRepV_0690Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (97 %)
Approved, Investigational
23577127
DrugRepV_0691Trihexyphenidyl
Nervous System
Parkinson Disease
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (97 %)
Approved
23577127
DrugRepV_0692Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0693Biperiden
Nervous System
Parkinson disease
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0694Carprofen
Anti-inflammatory
Joint pain
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved, Withdrawn
23577127
DrugRepV_0695Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease
Approved
23577127
DrugRepV_0696Dibucaine
Nervous System
Anesthesia
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0697Diphenoxylate
Alimentary Tract and Metabolism
Diarrhea
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease
Approved
23577127
DrugRepV_0698Diphenylpyraline
Respiratory System
Allergies
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease
Approved
23577127
DrugRepV_0699Dipivefrin
Sensory Organ
Glaucoma
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0700Dirithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0701Erythromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0702Estradiol
Genito Urinary System and Sex Hormones
Vulvar and vaginal atrophy
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0703Fluoxetine
Nervous System
Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved, Vet approved
23577127
DrugRepV_0704Ketotifen
Respiratory System
Atopic asthma | Conjunctivitis
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease
Approved
23577127
DrugRepV_0705Mycophenolate Mofetil
Immunosuppressant
Organ rejection (immunosuppressants)
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved, Investigational
23577127
DrugRepV_0706Oxyphencyclimine
Alimentary Tract and Metabolism
Peptic ulcers
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0707Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved, Investigational
23577127
DrugRepV_0708Trihexyphenidyl
Nervous System
Parkinson Disease
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
No significant effect
Approved
23577127
DrugRepV_0709Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
Approved
23577127
DrugRepV_0710Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
GP derived Pseudovirus
NA
Luciferase virus entry activity
Decrease (50 %)
Approved
23577127
DrugRepV_0711Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
Approved
23577127
DrugRepV_0712Aminoquinoline-13
NA
Malaria
Marburg virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
NA
23577127
DrugRepV_0713Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
Musoke
NA
Immunoflourescence assay
Decrease (50 %)
Approved
23577127
DrugRepV_0714Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
Musoke
NA
Immunoflourescence assay
Decrease (50 %)
Approved
23577127
DrugRepV_0715Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Marburg virus
Musoke
NA
Immunoflourescence assay
Decrease (50 %)
Approved
23577127
DrugRepV_0716Aminoquinoline-13
NA
Malaria
Marburg virus
Musoke
NA
Immunoflourescence assay
Decrease (50 %)
NA
23577127
DrugRepV_0717Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
Approved
23577127
DrugRepV_0718Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
Approved
23577127
DrugRepV_0719Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
Approved
23577127
DrugRepV_0720Aminoquinoline-13
NA
Malaria
Ebola virus
GP derived Pseudovirus
NA
Luciferase reporter assay
Decrease (50 %)
NA
23577127
DrugRepV_0721Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease (50 %)
Approved
23577127
DrugRepV_0722Hydroxychloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease (50 %)
Approved
23577127
DrugRepV_0723Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease (50 %)
Approved
23577127
DrugRepV_0724Aminoquinoline-13
NA
Malaria
Ebola virus
EBOLA-eGFP
NA
Fluorescence-based assay
Decrease (50 %)
NA
23577127
DrugRepV_0725Prochlorperazine
Nervous System
Nausea | Vomiting | Schizophrenia
Ebola virus
ma-EBOV
NA
NA
No significant effect
Approved
23577127
DrugRepV_0726Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
ma-EBOV
NA
NA
Increase
Approved
23577127
DrugRepV_0727Dirithromycin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
ma-EBOV
NA
NA
No significant effect
Approved
23577127
DrugRepV_0728Erythromycin ethylsuccinate
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
ma-EBOV
NA
NA
No significant effect
Approved
23577127
DrugRepV_0729Amlodipine
Cardiovascular agents
Hypertension
Ebola virus
ma-EBOV
NA
NA
No significant effect
Approved
23577127
DrugRepV_0730Fluoxetine
Nervous System
Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia
Ebola virus
ma-EBOV
NA
NA
No significant effect
Approved, Vet approved
23577127
DrugRepV_0731Penbutolol
Cardiovascular agents
Arterial hypertension
Ebola virus
ma-EBOV
NA
NA
No significant effect
Approved, Investigational
23577127
DrugRepV_0756Favipiravir
Antiviral
Influenza virus
Ebola virus
NA
NA
NA
Increase (7 %)
Investigational
26930627
DrugRepV_0757Favipiravir
Antiviral
Influenza virus
Ebola virus
NA
NA
Real-time PCR
No significant effect
Investigational
26930627
DrugRepV_0758Favipiravir
Antiviral
Influenza virus
Ebola virus
NA
NA
NA
Decrease (33 %)
Investigational
26930627
DrugRepV_0759Favipiravir
Antiviral
Influenza virus
Ebola virus
NA
NA
Real-time PCR
Decrease
Investigational
26930627
DrugRepV_1615Quinacrine Hydrochloride
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
Recombinant, infectious Ebola virus encoding green fluorescent protein
NA
Cell based assay
Decrease (50 %)
Investigational
26834994
DrugRepV_1616Pyronaridine tetraphosphate
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Recombinant, infectious Ebola virus encoding green fluorescent protein
NA
Cell based assay
Decrease (50 %)
Approved
26834994
DrugRepV_1617Tilorone Dihydrochloride
NA
Viral infections
Ebola virus
Recombinant, infectious Ebola virus encoding green fluorescent protein
NA
Cell based assay
Decrease (50 %)
NA
26834994
DrugRepV_1618Chloroquine Diphosphate
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Recombinant, infectious Ebola virus encoding green fluorescent protein
NA
Cell based assay
Decrease (50 %)
Approved
26834994
DrugRepV_2015Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2016Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2017Clemastine
Respiratory System
Allergic rhinitis
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2018Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved, Investigational
26585243
DrugRepV_2019Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved, Investigational
26585243
DrugRepV_2020Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved, Investigational
26585243
DrugRepV_2021Clomiphene
Genito Urinary System and Sex Hormones
Cancer
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2022Securinine
Anticancer
NA
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
NA
26585243
DrugRepV_2023Glafenine
Nervous System
Inflammatory disease
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
NA
26585243
DrugRepV_2024Oxeladin
Respiratory-Tract-agents
Cough
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Withdrawn
26585243
DrugRepV_2025Pimethixene Maleate
Respiratory System
NA
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2026Artemisinin
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Experimental
26585243
DrugRepV_2027Indoprofen
Musculo-Skeletal System
Inflammatory disease
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Withdrawn
26585243
DrugRepV_2028Iodoquinol
Genito Urinary System and Sex Hormones
Amoebiasis
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2029Levonordefrin
NA
Dental disorders
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2030Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (90 %)
Approved
26585243
DrugRepV_2031Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (50 %)
Approved
26585243
DrugRepV_2032Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (87.5 %)
Approved
26585243
DrugRepV_2033Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
Decrease (95 %)
Approved
26585243
DrugRepV_2034Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
Zaire strain-pEBOV
NA
Firefly luciferase assay
No significant effect (0 %)
Approved
26585243
DrugRepV_2071Diphenhydramine
Dermatologicals and Respiratory System
Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2072Chlorcyclizine
Respiratory System
Allergic rhinitis
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2073Diphenhydramine
Dermatologicals and Respiratory System
Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2074Chlorcyclizine
Respiratory System
Allergic rhinitis
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2075Cetirizine
Respiratory System
Allergic rhinitis
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
No significant decrease (50 %)
Approved
29981374
DrugRepV_2076Cetirizine
Respiratory System
Allergic rhinitis
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
No significant decrease (50 %)
Approved
29981374
DrugRepV_2077Fexofenadine
Respiratory System
Allergic rhinitis
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
No significant decrease (50 %)
Approved, Investigational
29981374
DrugRepV_2078Fexofenadine
Respiratory System
Allergic rhinitis
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
No significant decrease (50 %)
Approved, Investigational
29981374
DrugRepV_2079Tiotidine
NA
NA
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
No significant decrease (50 %)
NA
29981374
DrugRepV_2080Tiotidine
NA
NA
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
No significant decrease (50 %)
NA
29981374
DrugRepV_2081Impentamine
NA
NA
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
No significant decrease (50 %)
NA
29981374
DrugRepV_2082Impentamine
NA
NA
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
No significant decrease (50 %)
NA
29981374
DrugRepV_2083JNJ7777120
Anti-inflammatory
Pruritus (itching)
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
NA
29981374
DrugRepV_2084JNJ7777120
Anti-inflammatory
Pruritus (itching)
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
NA
29981374
DrugRepV_2085Nordiphenhydramine
NA
NA
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
NA
29981374
DrugRepV_2086Nordiphenhydramine
NA
NA
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
NA
29981374
DrugRepV_2087Orphenadrine
Nervous System
Parkinson's disease | Muscle spasm
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2088Orphenadrine
Nervous System
Parkinson's disease | Muscle spasm
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2089Chlorphenoxamine
Respiratory System
Parkinson's
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Withdrawn
29981374
DrugRepV_2090Chlorphenoxamine
Respiratory System
Parkinson's
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Withdrawn
29981374
DrugRepV_2091Carbinoxamine
Respiratory System
Allergic rhinitis
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2092Carbinoxamine
Respiratory System
Allergic rhinitis
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2093Doxylamine
Respiratory System
Allergies and an antitussive, antiemetic, and hypnotic
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2094Doxylamine
Respiratory System
Allergies and an antitussive, antiemetic, and hypnotic
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
No significant decrease (50 %)
Approved
29981374
DrugRepV_2095Hydroxyzine
Nervous System
Anxiety | Tension
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2096Hydroxyzine
Nervous System
Anxiety | Tension
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2097Cyclizine
Respiratory System
Nausea, vomiting, and dizziness
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2098Cyclizine
Respiratory System
Nausea, vomiting, and dizziness
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2099Buclizine
Respiratory System
Nausea, vomiting, and dizziness
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2100Buclizine
Respiratory System
Nausea, vomiting, and dizziness
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2101Meclizine
Respiratory System
Nausea | Vomiting | Motion sickness | Vertigo
Ebola virus
HIV/EBOV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2102Meclizine
Respiratory System
Nausea | Vomiting | Motion sickness | Vertigo
Marburg virus
HIV/MARV
NA
Luciferase reporter assay
Decrease (50 %)
Approved
29981374
DrugRepV_2103Diphenhydramine
Dermatologicals and Respiratory System
Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite
Ebola virus
EBOV/kikwit
NA
Immunoblot assay
Decrease (50 %)
Approved
29981374
DrugRepV_2104Chlorcyclizine
Respiratory System
Allergic rhinitis
Ebola virus
EBOV/kikwit
NA
Immunoblot assay
Decrease (50 %)
Approved
29981374
DrugRepV_2105Diphenhydramine
Dermatologicals and Respiratory System
Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite
Ebola virus
EBOV/kikwit
NA
Immunoblot assay
Decrease (50 %)
Approved
29981374
DrugRepV_2106Chlorcyclizine
Respiratory System
Allergic rhinitis
Ebola virus
EBOV/kikwit
NA
Immunoblot assay
Decrease (50 %)
Approved
29981374
DrugRepV_3566Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV/Mak
NA
Luminescence assay
Decrease (50 %)
Approved, Investigational
30016444
DrugRepV_3567Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV/Mak
NA
Luminescence assay
Decrease (50 %)
Approved, Investigational
30016444
DrugRepV_3568Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV/Mak
NA
Luminescence assay
Decrease (50 %)
Approved, Investigational
30016444
DrugRepV_3569Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV/May-GPA
NA
Luminescence assay
Decrease (50 %)
Approved, Investigational
30016444
DrugRepV_3570Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV/May-GPA
NA
Luminescence assay
Decrease (50 %)
Approved, Investigational
30016444
DrugRepV_3571Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3572Trifluoperazine
Nervous System
Schizophrenia and other psychotic disorders
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3573Clomipramine
Nervous System
Depression, schizophrenia, Tourette disorder
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3574Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Investigational
30149038
DrugRepV_3575Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Investigational
30149038
DrugRepV_3576Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Investigational
30149038
DrugRepV_3577Tamoxifen
Antineoplastic and Immunomodulating Agents
Breast cancer
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3578AY9944
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3579Paroxetine
Nervous System
Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Investigational
30149038
DrugRepV_3580Thioridazine
Nervous System
Schizophrenia | Anxiety disorder
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Withdrawn
30149038
DrugRepV_3581GBR-12783
NA
Psychosis
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3582Tabimorelin
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3583Asenapine
Nervous System
Psychosis
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3584Camylofine
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3585Bisacodyl
Alimentary Tract and Metabolism
Colon cleansing
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3586Bisacodyl
Alimentary Tract and Metabolism
Colon cleansing
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3587ML9
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3588Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3589Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved
30149038
DrugRepV_3590Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Investigational
30149038
DrugRepV_3591Bepridil
Cardiovascular agents
Hypertension and angina
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Withdrawn
30149038
DrugRepV_3592Amiodarone
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
Approved, Investigational
30149038
DrugRepV_3593Iminodyn 17
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3594Nobiletin
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3595Ferroquine
Antimalarial
Malaria
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3596N-Acetyl-L-leucyl- L- leucyl-L- methional
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3597Calpeptin
NA
NA
Ebola virus
EBOV trVLP
NA
Luciferase reporter assay
Decrease (50 %)
NA
30149038
DrugRepV_3627Cyanovirin-N
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
15073681
DrugRepV_3628Cyanovirin-N
NA
NA
Marburg virus
NA
NA
Luciferase assay
Decrease (50 %)
NA
15073681
DrugRepV_3629Cyanovirin-N
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
15073681
DrugRepV_3630N-methyl-5,7-dinitro-N-propylquinolin-8-amine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36312-[3-(4-chlorophenyl)-1-(3-methoxyphenyl)-3-oxopropyl]propanedinitrile
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_3632(19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,9,15(20)-pentaene-14,18-dione
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36332-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_3634N-(3,4-dichlorophenyl)-5-nitrofuran-2-carboxamide
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36357-[(furan-2-yl)methyl]-3-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-imine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36362-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_3637N,N-bis(4-methylphenyl)pyridin-3-amine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_3638N-methyl-5,7-dinitro-N-propylquinolin-8-amine
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36392-[3-(4-chlorophenyl)-1-(3-methoxyphenyl)-3-oxopropyl]propanedinitrile
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_3640(19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,9,15(20)-pentaene-14,18-dione
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36412-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]-3-[3-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-one
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_3642N-(3,4-dichlorophenyl)-5-nitrofuran-2-carboxamide
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36437-[(furan-2-yl)methyl]-3-[3-(1H-imidazol-1-yl)propyl]-5,6-diphenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-imine
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36442-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_3645N,N-bis(4-methylphenyl)pyridin-3-amine
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36462-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Ebola virus
Zaire
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36472-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Marburg virus
NA
NA
Luciferase assay
Decrease (50 %)
NA
21270170
DrugRepV_36522-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36532-methyl-4-phenyl-1H-naphtho[2,3-b][1,4]diazepine hydrochloride
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36542-(4-chlorophenyl)-7,8-dimethyl-4-(trifluoromethyl)-3H-1,5-benzodiazepine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36552-(1,1,2,2,2-pentafluoroethyl)-4-phenyl-3H-1,5-benzodiazepine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36567,8-dichloro-2-(1,1,2,2,2-pentafluoroethyl)-4-phenyl-3H-1,5-benzodiazepine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36572-[4-(trifluoromethyl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36582-(4-methylphenyl)-4-(trifluoromethyl)-3H-1,5-benzodiazepine
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36594-methoxy-2-[4-(trifluoromethyl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36602-[4-(thiophen-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36614-chloro-2-[4-(furan-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36624-methoxy-2-[4-(thiophen-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36632-[4-(furan-2-yl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36642-[4-(3-nitrophenyl)-3H-1,5-benzodiazepin-2-yl]phenol
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (90 %)
NA
21270170
DrugRepV_36652-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Marburg virus
Lake Victoria
NA
Luciferase reporter assay
Decrease (90 %)
NA
21270170
DrugRepV_36662-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Marburg virus
Lake Victoria
NA
Luciferase reporter assay
Decrease (50 %)
NA
21270170
DrugRepV_36672-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Marburg virus
Lake Victoria
NA
Luciferase reporter assay
Decrease (100 %)
NA
21270170
DrugRepV_36682-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine
NA
NA
Marburg virus
Lake Victoria
NA
Luciferase reporter assay
Decrease (98 %)
NA
21270170
DrugRepV_36712,6-bis[(3-tert-butyl-2-hydroxy-5-methylphenyl)methyl]-4-methylphenol
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (100 %)
NA
22027648
DrugRepV_3672NSC 62914
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease
NA
22027648
DrugRepV_3673NSC 62914
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
NA
22027648
DrugRepV_3674Trolox
NA
NA
Ebola virus
Zaire
NA
RT-PCR
Decrease (45 %)
NA
22027648
DrugRepV_3675Trolox
NA
NA
Marburg virus
NA
NA
RT-PCR
Decrease (70 %)
NA
22027648
DrugRepV_3676NSC 62914
NA
NA
Marburg virus
Ci67
NA
RT-PCR
Decrease (98 %)
NA
22027648
DrugRepV_3679NSC 62914
NA
NA
Ebola virus
NA
NA
NA
Decrease
NA
22027648
DrugRepV_3680NSC 62914
NA
NA
Marburg virus
NA
NA
NA
Decrease
NA
22027648
DrugRepV_3681N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine tetrahydrochloride
NA
NA
Ebola virus
Zaire-95
NA
NA
Decrease (50 %)
NA
23012625
DrugRepV_3682N5,N14-bis[2-(morpholin-4-yl)ethyl]-3,12-bis({[2-(morpholin-4-yl)ethyl]amino})-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-5,14-dicarboxamide; hexakis(trifluoroacet
NA
NA
Ebola virus
Zaire-95
NA
NA
Decrease (50 %)
NA
23012625
DrugRepV_3683N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine
NA
NA
Ebola virus
Zaire-95
NA
NA
Decrease (50 %)
NA
23012625
DrugRepV_3684N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine tetrahydrochloride
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
23012625
DrugRepV_3685N3,N12-bis[2-(morpholin-4-yl)ethyl]-6,15-diazatetracyclo[8.8.0.02,7.011,16]octadeca-1(10),2,4,6,8,11(16),12,14,17-nonaene-3,12-diamine
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
23012625
DrugRepV_3686BCX4430
NA
Ebola virus
Marburg virus
Musoke
NA
RT-PCR
Decrease (50 %)
Investigational
24590073
DrugRepV_3687BCX4430
NA
Ebola virus
Marburg virus
Ci67
NA
RT-PCR
Decrease (50 %)
Investigational
24590073
DrugRepV_3688BCX4430
NA
Ebola virus
Marburg virus
Angola
NA
RT-PCR
Decrease (50 %)
Investigational
24590073
DrugRepV_3689BCX4430
NA
Ebola virus
Ebola virus
Kikwit
NA
RT-PCR
Decrease (50 %)
Investigational
24590073
DrugRepV_3697Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Marburg virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
24713118
DrugRepV_36986-Azauridine
NA
Cancer
Marburg virus
NA
NA
Luciferase assay
Decrease (50 %)
NA
24713118
DrugRepV_36992-C-Methylcytidine
NA
Hepatitis C virus
Marburg virus
NA
NA
Luciferase assay
Decrease (50 %)
Experimental
24713118
DrugRepV_3700Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
24713118
DrugRepV_37016-Azauridine
NA
Cancer
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
NA
24713118
DrugRepV_37022-C-Methylcytidine
NA
Hepatitis C virus
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Experimental
24713118
DrugRepV_3703Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Marburg virus
NA
NA
NA
Decrease (83 %)
Approved
24713118
DrugRepV_37046-Azauridine
NA
Cancer
Marburg virus
NA
NA
NA
Decrease (98 %)
NA
24713118
DrugRepV_3705Chloroquine
Malaria
Malaria
Marburg virus
NA
NA
NA
Decrease (99.9 %)
Approved
24713118
DrugRepV_3706Imatinib Methanesulfonate Salt
Antineoplastic and Immunomodulating Agents
NA
Marburg virus
NA
NA
NA
Decrease (99 %)
Approved
24713118
DrugRepV_3707Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Ebola virus
NA
NA
NA
Decrease (0 %)
Approved
24713118
DrugRepV_37086-Azauridine
NA
Cancer
Ebola virus
NA
NA
NA
Decrease (99 %)
NA
24713118
DrugRepV_3709Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
NA
NA
NA
Decrease (99.9 %)
Approved
24713118
DrugRepV_3710Imatinib Methanesulfonate Salt
Antineoplastic and Immunomodulating Agents
NA
Ebola virus
NA
NA
NA
Decrease (95 %)
Approved
24713118
DrugRepV_3715C795-0925
NA
NA
Ebola virus
Zaire
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3716D011-2120
NA
NA
Ebola virus
Zaire
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3717F694-1532
NA
NA
Ebola virus
Zaire
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3718G202-0362
NA
NA
Ebola virus
Zaire
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3719C795-0925
NA
NA
Marburg virus
Ci67
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3720D011-2120
NA
NA
Marburg virus
Ci67
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3721F694-1532
NA
NA
Marburg virus
Ci67
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3722G202-0362
NA
NA
Marburg virus
Ci67
NA
RT-PCR
Decrease (50 %)
NA
25144302
DrugRepV_3735OSU-03012
Anticancer
Brain cancer
Ebola virus
NA
NA
GFP assay
Decrease (50 %)
NA
25986249
DrugRepV_3736OSU-03012
Anticancer
Brain cancer
Marburg virus
NA
NA
GFP assay
Decrease (50 %)
NA
25986249
DrugRepV_3739Falnidamol dihydrochloride
NA
Solid Tumor
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
Investigational
25986249
DrugRepV_3740Falnidamol dihydrochloride
NA
Solid Tumor
Marburg virus
NA
NA
RT-PCR
Decrease (50 %)
Investigational
25986249
DrugRepV_3743OSU-03012
Anticancer
Brain cancer
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
NA
25986249
DrugRepV_3744Falnidamol
NA
Solid Tumor
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
Investigational
25986249
DrugRepV_3745Falnidamol
NA
Solid Tumor
Ebola virus
1976
NA
Firefly luciferase assay
Decrease (50 %)
Investigational
25986249
DrugRepV_3746Falnidamol
NA
Solid Tumor
Ebola virus
2014
NA
Firefly luciferase assay
Decrease (50 %)
Investigational
25986249
DrugRepV_3748Amiodarone Hydrochloride
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
1976
NA
Firefly luciferase assay
Decrease (50 %)
Approved
25986249
DrugRepV_3749Amiodarone Hydrochloride
Cardiovascular agents
Anginal and Arrhythmia
Ebola virus
2014
NA
Firefly luciferase assay
Decrease (50 %)
Approved
25986249
DrugRepV_3751MLS000078751
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3752MLS000394177
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3753MLS000534476
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3754MLS000554255
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3755MLS000555232
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3756MLS000730532
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3757MLS000733230
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3758MLS000762907
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3759MLS001101371
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3760MLS000078751
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3761MLS000394177
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3762MLS000534476
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3763MLS000554255
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3764MLS000555232
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3765MLS000730532
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3766MLS000733230
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3767MLS000762907
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3768MLS001101371
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3769MLS001239325
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3770MLS001239325
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3771MLS001030162
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3772MLS001030162
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3773MLS000666802
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3774MLS000666802
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3775MLS000999960
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3776MLS000999960
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3777MLS001173370
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3778MLS001173370
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3779MLS001174896
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3780MLS001174896
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3781MLS001196083
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3782MLS001196083
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3783MLS001239358
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3784MLS001239358
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3785MLS001177927
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3786MLS001177927
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3787MLS001209453
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3788MLS001209453
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3789MLS000580080
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3790MLS000580080
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3791MLS000106706
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3792MLS000106706
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3793MLS001175455
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3794MLS001175455
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3795MLS000772389
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3796MLS000772389
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3797MLS000042810
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3798MLS000042810
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3799MLS001162808
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3800MLS001162808
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3801MLS000684231
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3802MLS000684231
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3803MLS000556387
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3804MLS000556387
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3805MLS001179278
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3806MLS001179278
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3807MLS000567464
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3808MLS000567464
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3809MLS000583959
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3810MLS000583959
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3811MLS001018888
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3812MLS001018888
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3813MLS001047402
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3814MLS001047402
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3815MLS001029946
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3816MLS001029946
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3817MLS000332573
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3818MLS000332573
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3819MLS000936259
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3820MLS000936259
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3821MLS000718690
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3822MLS000718690
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3823MLS000880330
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3824MLS000880330
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3825MLS001207131
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3826MLS001207131
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3827MLS000673118
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3828MLS000673118
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3829MLS000689481
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3830MLS000689481
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3831MLS001179272
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3832MLS001179272
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3833MLS002702500
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3834MLS002702500
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3835MLS001180408
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3836MLS000737975
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3837MLS001237534
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3838MLS000336293
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3839MLS000780111
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3840MLS001179997
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3841MLS000418057
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3842MLS000936795
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3843MLS000092187
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3844MLS000391391
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3845MLS000569139
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3846MLS001045935
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3847MLS001181479
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3848MLS000391984
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3849MLS000063146
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3850MLS000768081
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3851MLS000091920
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3852MLS001150589
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3853MLS000736237
NA
NA
Marburg virus
Musoke
NA
NA
Decrease (50 %)
NA
27161622
DrugRepV_3854Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
Approved
27490565
DrugRepV_3855Enclomiphene
NA
Male hypogonadism
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
Investigational
27490565
DrugRepV_3856Zuclomiphene
NA
NA
Ebola virus
Mayinga
NA
NA
Decrease (50 %)
NA
27490565
DrugRepV_3857Clomiphene
Genito Urinary System and Sex Hormones
Polycystic ovary syndrome
Ebola virus
Mayinga
NA
Renilla luciferase assay
Decrease (100 %)
Approved
27490565
DrugRepV_3858Enclomiphene
NA
Male hypogonadism
Ebola virus
Mayinga
NA
Renilla luciferase assay
Decrease (100 %)
Investigational
27490565
DrugRepV_3859Zuclomiphene
NA
NA
Ebola virus
Mayinga
NA
Renilla luciferase assay
Decrease (100 %)
NA
27490565
DrugRepV_3860Favipiravir
Antiviral
Influenza virus
Marburg virus
Leiden
NA
RT-PCR
Decrease (50 %)
Investigational
27736754
DrugRepV_3865Favipiravir
Antiviral
Influenza virus
Ebola virus
Mayinga 1976
NA
MTT assay
Decrease (50 %)
Investigational
27736754
DrugRepV_3866Favipiravir
Antiviral
Influenza virus
Ebola virus
Kikwit 1995/E718
NA
NA
Decrease (50 %)
Investigational
27736754
DrugRepV_3883UV-1
NA
NA
Ebola virus
Zaire-Kikwit
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3884UV-2
NA
NA
Ebola virus
Zaire-Kikwit
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3885UV-3
NA
NA
Ebola virus
Zaire-Kikwit
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3886UV-4
NA
NA
Ebola virus
Zaire-Kikwit
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3887UV-5
NA
NA
Ebola virus
Zaire-Kikwit
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3888UV-1
NA
NA
Marburg virus
Ci67
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3889UV-2
NA
NA
Marburg virus
Ci67
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3890UV-3
NA
NA
Marburg virus
Ci67
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3891UV-4
NA
NA
Marburg virus
Ci67
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3892UV-5
NA
NA
Marburg virus
Ci67
NA
Plaque assay
Decrease (50 %)
NA
27908828
DrugRepV_3893cp15
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3894cp15
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3895cp15
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3896cp15
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3897cp19
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3898cp19
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3899cp19
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3900cp19
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3901cp3
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3902cp5
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3903cp11
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3904cp13
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3905cp15
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3906cp16
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3907cp19
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3908cp3
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3909cp5
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3910cp11
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3911cp13
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3912cp15
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3913cp16
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3914cp19
NA
NA
Marburg virus
Ci67
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3915cp3
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3916cp5
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3917cp11
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3918cp13
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3919cp15
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3920cp16
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3921cp19
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3922CBS1129
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3923CBS1130
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3924CBS1131
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3925CBS1132
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3926CBS1133
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3927CBS1134
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3928CBS1135
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3929CBS1136
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3930CBS1137
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3931CBS1138
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3932CBS1139
NA
NA
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
NA
28645623
DrugRepV_3934IHVR-19029
NA
NA
Ebola virus
NA
NA
Immunolabeling assay
Decrease (50 %)
NA
29253498
DrugRepV_3935Favipiravir
Antiviral
Influenza virus
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
Investigational
29289664
DrugRepV_3936Favipiravir
Antiviral
Influenza virus
Ebola virus
Makona
NA
NA
Decrease (50 %)
Investigational
29289664
DrugRepV_3937Favipiravir
Antiviral
Influenza virus
Marburg virus
Ci67
NA
NA
Decrease (50 %)
Investigational
29289664
DrugRepV_3938GSK983
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3939Angelicin
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3940Benzoquinoline
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3941SW539
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3942SW320
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3943SW351
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3944SW491
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3945SW490
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3946SW388
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3947SW386
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3948SW349
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3949SW991
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3950SW456
NA
NA
Ebola virus
NA
NA
Plaque assay
Decrease (50 %)
NA
29294299
DrugRepV_3951Favipiravir
Antiviral
Influenza virus
Marburg virus
NA
NA
qRT-PCR
Decrease (50 %)
Investigational
29369776
DrugRepV_3952Favipiravir
Antiviral
Influenza virus
Marburg virus
NA
NA
qRT-PCR
Decrease
Investigational
29369776
DrugRepV_395312N-p-dichlorobenzyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_395412N-o-methylbenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_395512N-2,4-dichlorobenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_395612N-3,5 -dichlorobenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_395712N-3,4-dichlorobenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_395812N-m-methoxybenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_395912N-benzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396012N-p-trifluoromethoxylbenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396112N-p-fluorobenzyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396212N-3,5-dichlorobenzoyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396312N-p-chlorobenzoyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396412N-3,4-dichlorobenzoyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396512N-3,4-dichlorobenzenesulfonyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396612N-3,5-dichlorobenzenesulfonyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396712N-o-thiophenesulfonyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396812N-m-cyanobenzenesulfonyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_396912N-p-chlorobenzenesulfonyl aloperine
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397012N-p-chlorophenylethyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397112N-3,4-dichlorophenylethyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397212N-3,5-dichlorophenylethyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397312N-3,4-dichlorohydrocinnamyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397412N-3,5-dichlorohydrocinnamyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397512N-p-chlorohydrocinnamyl aloperine dihydrochloride
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397612N-p-dichlorobenzyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397712N-o-methylbenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397812N-2,4-dichlorobenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_397912N-3,5 -dichlorobenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398012N-3,4-dichlorobenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398112N-m-methoxybenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398212N-benzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398312N-p-trifluoromethoxylbenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398412N-p-fluorobenzyl aloperine dihydrochloride
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398512N-3,5-dichlorobenzoyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398612N-p-chlorobenzoyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398712N-3,4-dichlorobenzoyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398812N-3,4-dichlorobenzenesulfonyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_398912N-3,5-dichlorobenzenesulfonyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_399012N-o-thiophenesulfonyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_399112N-m-cyanobenzenesulfonyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_399212N-p-chlorobenzenesulfonyl aloperine
NA
NA
Marburg virus
NA
NA
NA
Decrease (50 %)
NA
29494844
DrugRepV_3994Genistein
Antihelmintic
Prostate cancer
Marburg virus
NA
NA
Luciferase assay
Decrease (75 %)
Investigational
21947546
DrugRepV_3995Genistein
Antihelmintic
Prostate cancer
Ebola virus
NA
NA
Luciferase assay
Decrease (87 %)
Investigational
21947546
DrugRepV_3997Tyrphostin AG1478
NA
NA
Marburg virus
NA
NA
Luciferase assay
Decrease (100 %)
NA
21947546
DrugRepV_3998Tyrphostin AG1478
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (100 %)
NA
21947546
DrugRepV_4000Genistein-Tyrphostin AG1478
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (99 %)
NA
21947546
DrugRepV_4001FGI-103
NA
NA
Ebola virus
Zaire
NA
Plaque assay
Decrease (50 %)
NA
20211898
DrugRepV_4002FGI-103
NA
NA
Ebola virus
Sudan
NA
Plaque assay
Decrease (50 %)
NA
20211898
DrugRepV_4003FGI-103
NA
NA
Marburg virus
Ravn
NA
Plaque assay
Decrease (50 %)
NA
20211898
DrugRepV_4004FGI-103
NA
NA
Marburg virus
Ci67
NA
Plaque assay
Decrease (95 %)
NA
20211898
DrugRepV_4005FGI-103
NA
NA
Ebola virus
Zaire
NA
NA
Decrease
NA
20211898
DrugRepV_4088Bafilomycin A1
Antibiotics
NA
Ebola virus
Mayinga
NA
Inhibition assay
Decrease (50 %)
Experimental
26069727
DrugRepV_4089Bafilomycin A1
Antibiotics
NA
Ebola virus
Bundibugyo
NA
Inhibition assay
Decrease (50 %)
Experimental
26069727
DrugRepV_4090Bafilomycin A1
Antibiotics
NA
Marburg virus
Lake Victoria isolate
NA
Inhibition assay
Decrease (50 %)
Experimental
26069727
DrugRepV_4092Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Mayinga
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4093Chloroquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Bundibugyo
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4094Chloroquine
Malaria
Malaria
Marburg virus
Lake Victoria isolate
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4096Omeprazole
Alimentary Tract and Metabolism
Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD
Ebola virus
Bundibugyo
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4097Omeprazole
Alimentary Tract and Metabolism
Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD
Marburg virus
Lake Victoria isolate
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4099Esomeprazole
Alimentary Tract and Metabolism
Acid-reflux disorders (GERD) and peptic ulcer disease
Ebola virus
Mayinga
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4100Esomeprazole
Alimentary Tract and Metabolism
Acid-reflux disorders (GERD) and peptic ulcer disease
Ebola virus
Bundibugyo
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4101Esomeprazole
Alimentary Tract and Metabolism
Acid-reflux disorders (GERD) and peptic ulcer disease
Marburg virus
Lake Victoria isolate
NA
Inhibition assay
Decrease (50 %)
Approved
26069727
DrugRepV_4302Carbocyclic adenosine
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_4303Carbocyclic 3-deazaadenosine
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_43049-[trans- 2,trans - 3 - dihydroxy - 4 - (methyl) - cyclopent - 4 - enyl] - 3 - deazaadenine
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_43059-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-adenine
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_43069-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-3-deazaadenine
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_43079-[trans-2,trans-3-dihydroxycyclopent-4-enyl]- adenine (DHCpAdo)
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_43089-[trans-2,trans-3-dihydroxycyclopent- 4-enyl]-3-deazaadenine (DHCp-c3Ado)
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_43094,5- didehydro-5-deoxy-5-fluoroadenosine (DDFA)
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_4310Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
Approved
9988190
DrugRepV_4311Guanosine Dialdehyde
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
NA
9988190
DrugRepV_4312Adenosine Dialdehyde
NA
NA
Ebola virus
Mayinga
NA
MTT assay
Decrease (50 %)
Approved, Investigational
9988190
DrugRepV_4313Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Ebola virus
Sudan (Boneface strain)
NA
Plaque reduction assay
Decrease (50 %)
Approved
9988190
DrugRepV_4314Carbocyclic 3-deazaadenosine
NA
NA
Ebola virus
Sudan (Boneface strain)
NA
Plaque reduction assay
Decrease (50 %)
NA
9988190
DrugRepV_43159-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-adenine
NA
NA
Ebola virus
Sudan (Boneface strain)
NA
Plaque reduction assay
Decrease (50 %)
NA
9988190
DrugRepV_43169-[trans-2,trans-3-dihydroxy-4-hydroxymethyl-cyclopent-4-enyl]-3-deazaadenine
NA
NA
Ebola virus
Sudan (Boneface strain)
NA
Plaque reduction assay
Decrease (50 %)
NA
9988190
DrugRepV_4317Carbocyclic 3-deazaadenosine
NA
NA
Ebola virus
EBO-Z
NA
Survival assay
Increase
NA
9988190
DrugRepV_4318FGI-106
NA
NA
Ebola virus
Zaire
NA
Plaque assay
Decrease (50 %)
NA
19523489
DrugRepV_4320FGI-106
NA
NA
Ebola virus
Zaire
NA
Survival assay
Increase
NA
19523489
DrugRepV_4321N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (44.6 %)
NA
24501399
DrugRepV_4322N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (32.6 %)
NA
24501399
DrugRepV_43239H-carbazol-3-amine
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (6.1 %)
NA
24501399
DrugRepV_43247-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-3.8 %)
NA
24501399
DrugRepV_4325N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-16 %)
NA
24501399
DrugRepV_4326tris[4-(dimethylamino)phenyl]methanol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (31.8 %)
NA
24501399
DrugRepV_43276-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (31.8 %)
NA
24501399
DrugRepV_43281-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-1.6 %)
NA
24501399
DrugRepV_43292-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-1.8 %)
NA
24501399
DrugRepV_4330N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (66.3 %)
NA
24501399
DrugRepV_43314-{[(5-methyl-2-thienyl)methyl]amino}phenol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-12.6 %)
NA
24501399
DrugRepV_4332N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-3.4 %)
NA
24501399
DrugRepV_4333N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.2 %)
NA
24501399
DrugRepV_43342-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (8.6 %)
NA
24501399
DrugRepV_4335N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (66.9 %)
NA
24501399
DrugRepV_4336N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (9.6 %)
NA
24501399
DrugRepV_43374-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (34 %)
NA
24501399
DrugRepV_4338N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (11.6 %)
NA
24501399
DrugRepV_4339N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (45.7 %)
NA
24501399
DrugRepV_4340N-(3-chlorophenyl)-N-(4-cyanophenyl)urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.1 %)
NA
24501399
DrugRepV_4341N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-3.4 %)
NA
24501399
DrugRepV_4342N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (5.7 %)
NA
24501399
DrugRepV_43434,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-24.6 %)
NA
24501399
DrugRepV_43441-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (13.1 %)
NA
24501399
DrugRepV_43452-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (6.4 %)
NA
24501399
DrugRepV_4346N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (6.2 %)
NA
24501399
DrugRepV_43472-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.7 %)
NA
24501399
DrugRepV_4348N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (2.1 %)
NA
24501399
DrugRepV_43494,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-0.6 %)
NA
24501399
DrugRepV_4350N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-2.6 %)
NA
24501399
DrugRepV_43513-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-6.1 %)
NA
24501399
DrugRepV_4352methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (82.4 %)
NA
24501399
DrugRepV_4353N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (33.4 %)
NA
24501399
DrugRepV_4354N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (25.4 %)
NA
24501399
DrugRepV_4355(1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.5 %)
NA
24501399
DrugRepV_43564-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (25.2 %)
NA
24501399
DrugRepV_4357N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (17.4 %)
NA
24501399
DrugRepV_43583-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (26.8 %)
NA
24501399
DrugRepV_43595-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-6.6 %)
NA
24501399
DrugRepV_43606-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (20.9 %)
NA
24501399
DrugRepV_43612-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-12.1 %)
NA
24501399
DrugRepV_4362N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (12.3 %)
NA
24501399
DrugRepV_43634-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (1.8 %)
NA
24501399
DrugRepV_43642-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (1.1 %)
NA
24501399
DrugRepV_43655-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-0.3 %)
NA
24501399
DrugRepV_43662-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-1.5 %)
NA
24501399
DrugRepV_43672-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-15.9 %)
NA
24501399
DrugRepV_4368N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-11.5 %)
NA
24501399
DrugRepV_43698-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-11.7 %)
NA
24501399
DrugRepV_4370N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (8.05 %)
NA
24501399
DrugRepV_4471Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-GFP
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4472Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-Gluc
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4473Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-GFP
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4474Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-GFP
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4475Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-GFP
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4476Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-GFP
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4477Brincidofovir
Antiviral
Viral infections
Ebola virus
EBOV-GFP
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4478Brincidofovir
Antiviral
Viral infections
Ebola virus
Mayinga
NA
Operetta High Content Imaging System
Decrease (50 %)
Investigational
26526586
DrugRepV_4479Brincidofovir
Antiviral
Viral infections
Ebola virus
Makona
NA
NA
Decrease (50 %)
Investigational
26526586
DrugRepV_4480Brincidofovir
Antiviral
Viral infections
Ebola virus
Ebola Zaire Kikwit
NA
Immunoflourescence assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4481Brincidofovir
Antiviral
Viral infections
Ebola virus
Ebola Zaire Kikwit
NA
Immunoflourescence assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4482Brincidofovir
Antiviral
Viral infections
Ebola virus
Ebola Zaire Kikwit
NA
Immunoflourescence assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4483Brincidofovir
Antiviral
Viral infections
Ebola virus
Ebola Zaire Makona
NA
Immunoflourescence assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4484Brincidofovir
Antiviral
Viral infections
Ebola virus
Ebola Zaire Makona
NA
Immunoflourescence assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4485Brincidofovir
Antiviral
Viral infections
Ebola virus
Ebola Zaire Makona
NA
Immunoflourescence assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4486Brincidofovir
NA
Viral infections
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
Investigational
26526586
DrugRepV_4487CMX029
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4488CMX021
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4489CMX028
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4490CMX16669
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4491CMX16663
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4492CMX167
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4493CMX157
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4494CMX101
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4495CMX004
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4496CMX16689
NA
NA
Ebola virus
EBOV-GFP
NA
Luciferase assay
Decrease (50 %)
NA
26526586
DrugRepV_4497Ranpirnase
Anticancer
Cancer
Ebola virus
Kikwit
NA
NA
Decrease (50 %)
Investigational
27350309
DrugRepV_4498Ranpirnase
Anticancer
Cancer
Ebola virus
Kikwit
NA
Fluorescence-based assay
Decrease
Investigational
27350309
DrugRepV_4499Ranpirnase
Anticancer
Cancer
Ebola virus
Kikwit
NA
NA
Increase
Investigational
27350309
DrugRepV_4500(1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
Zaire
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4501(1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
Zaire
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4502(1S,2R,5R)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
Zaire
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4503(1R,2S,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
Zaire
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4504(1R,2S,5R)-3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
Zaire
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4505(1S,2R,5S)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4506(1S,2R,5R)-5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4507(1S,2R,5R)-5-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4508(1R,2S,5R)-3-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4509(1R,2S,5R)-3-{4-amino-1H-imidazo[4,5-c]pyridin-1-yl}-5-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4510(1S,2R,5S)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-(hydroxymethyl)cyclopent-3-ene-1,2-diol
NA
NA
Ebola virus
NA
NA
NA
Decrease (50 %)
NA
30385162
DrugRepV_4512Favipiravir
Antiviral
Influenza virus
Ebola virus
NA
NA
NA
Increase
Investigational
30275474
DrugRepV_4513Remdesivir
Antiviral
Hepatitis C | Ebola
Ebola virus
NA
NA
NA
Increase
Experimental
30275474
DrugRepV_4514Favipiravir
Antiviral
Influenza virus
Ebola virus
NA
NA
NA
Increase
Investigational
29584730
DrugRepV_4822Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
26953343
DrugRepV_4823Teicoplanin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
26953343
DrugRepV_4824Dalbavancin
Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
26953343
DrugRepV_4825Oritavancin
Antiinfectives For Systemic Use
Acute bacterial skin | Skin structure infections
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
26953343
DrugRepV_4826Telavancin
Antiinfectives For Systemic Use
Skin infections (Bacterial)
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
26953343
DrugRepV_4827Vancomycin
Alimentary Tract and Metabolism; Antiinfectives For Systemic Use
Bacterial infections
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
Approved
26953343
DrugRepV_4828CTSL inhibitor
NA
NA
Ebola virus
NA
NA
Luciferase assay
Decrease (50 %)
NA
26953343
DrugRepV_5192C795-0925
NA
NA
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5193D011-2120
NA
NA
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5194F694-1532
NA
NA
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5195G202-0362
NA
NA
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5196Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Ebola virus
Zaire
NA
Immunoflourescence assay
Decrease (50 %)
Approved
25144302
DrugRepV_5197C795-0925
NA
NA
Marburg virus
Ci67
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5198D011-2120
NA
NA
Marburg virus
Ci67
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5199F694-1532
NA
NA
Marburg virus
Ci67
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5200G202-0362
NA
NA
Marburg virus
Ci67
NA
Immunoflourescence assay
Decrease (50 %)
NA
25144302
DrugRepV_5201Ribavirin
Antiinfectives For Systemic Use
Hepatitis C virus
Marburg virus
Ci67
NA
Immunoflourescence assay
Decrease (50 %)
Approved
25144302
DrugRepV_53271-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_5328diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_5329diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53301-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53312-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53321-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53331-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_5334{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53354,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53364,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53374,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53384,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53394,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53404,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53411-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53421-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53431-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53441-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide
NA
NA
Ebola virus
NA
NA
Real-time PCR
Decrease (50 %)
NA
15451189
DrugRepV_53495-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
NA
21616094
DrugRepV_53505-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
NA
21616094
DrugRepV_53515-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
NA
21616094
DrugRepV_53525-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
NA
21616094
DrugRepV_53575-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
NA
21616094
DrugRepV_53585-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
NA
21616094
DrugRepV_53595-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
NA
21616094
DrugRepV_53605-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide
NA
NA
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
NA
21616094
DrugRepV_5365Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
Approved
21616094
DrugRepV_5366Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
Approved
21616094
DrugRepV_5367Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
Approved
21616094
DrugRepV_5368Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (50 %)
Approved
21616094
DrugRepV_5373Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
Approved
21616094
DrugRepV_5374Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
Approved
21616094
DrugRepV_5375Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
Approved
21616094
DrugRepV_5376Mycophenolic Acid
Antineoplastic and Immunomodulating Agents
Organ rejection (immunosuppressants)
Ebola virus
NA
NA
RT-PCR
Decrease (90 %)
Approved
21616094
DrugRepV_53838-Azaadenosine
NA
NA
Ebola virus
Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2014
NA
Minigenome assays
Decrease (50 %)
NA
27771389
DrugRepV_5384Toyocamycin
NA
NA
Ebola virus
Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2015
NA
Minigenome assays
Decrease (50 %)
Experimental
27771389
DrugRepV_53856-Azauridine
NA
Cancer
Ebola virus
Ebola virus/H.sapiens-rec/LBR/2014/ Makona-L2016
NA
Minigenome assays
Decrease (50 %)
NA
27771389
DrugRepV_5386Quinacrine
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
NA
NA
qRT-PCR
Decrease
Investigational
31307979
DrugRepV_5388Quinacrine
NA
Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions
Ebola virus
NA
NA
NA
Decrease (50 %)
Investigational
31307979
DrugRepV_5394Zoniporide
NA
NA
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
NA
30700611
DrugRepV_5396Amodiaquine
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Approved
30700611
DrugRepV_5398Niclosamide
Antiparasitic products, Insectisides and Repellents
Tapeworm and intestinal fluke infections | Helminthiasis
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Approved
30700611
DrugRepV_5400Apilimod
NA
Crohn's disease | Psoriasis | Psoriatic disorders
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Investigational
30700611
DrugRepV_5402Arbidol
NA
Viral infection
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Investigational
30700611
DrugRepV_5404Clomiphene
Genito Urinary System and Sex Hormones
Female infertility
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Approved
30700611
DrugRepV_5406Sertraline
Nervous System
Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Approved
30700611
DrugRepV_5408Toremifene
Antineoplastic and Immunomodulating Agents
Breast Cancer
Ebola virus
Mayinga
NA
Luciferase assay
Decrease (50 %)
Approved, Investigational
30700611
DrugRepV_5491Amodiaquine Dihydrochloride Dihydrate
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
Approved, Investigational
31882748
DrugRepV_5492Amodiaquine Dihydrochloride Dihydrate
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
Approved, Investigational
31882748
DrugRepV_5493Amodiaquine Dihydrochloride Dihydrate
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
Approved, Investigational
31882748
DrugRepV_5494Artesunate
Antiparasitic products, Insectisides and Repellents
Malaria
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
Approved, Investigational
31882748
DrugRepV_5495Winthrop
NA
NA
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
NA
31882748
DrugRepV_5496Winthrop
NA
NA
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
NA
31882748
DrugRepV_5497Winthrop
NA
NA
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
NA
31882748
DrugRepV_5498N-Desethylamodiaquine hydrochloride
NA
NA
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
NA
31882748
DrugRepV_5499N-Desethylamodiaquine hydrochloride
NA
NA
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
NA
31882748
DrugRepV_5500N-Desethylamodiaquine hydrochloride
NA
NA
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
NA
31882748
DrugRepV_5501Dihydroartimesinin
NA
Malaria
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
Experimental, Investigational
31882748
DrugRepV_5502Dihydroartimesinin
NA
Malaria
Ebola virus
NA
NA
Cell based assay
Decrease (50 %)
Experimental, Investigational
31882748
DrugRepV_8294Tolcapone
Nervous System
Parkinson's Disease
Ebola virus
NA
NA
NA
Decrease (50 %)
Approved, Withdrawn
32425892
DrugRepV_8295Tolcapone
Nervous System
Parkinson's Disease
Ebola virus
NA
NA
NA
Decrease (50 %)
Approved, Withdrawn
32425892
DrugRepV_8296Tolcapone
Nervous System
Parkinson's Disease
Ebola virus
NA
NA
NA
Decrease (50 %)
Approved, Withdrawn
32425892
DrugRepV_8297Tolcapone
Nervous System
Parkinson's Disease
Ebola virus
NA
NA
NA
Decrease (50 %)
Approved, Withdrawn
32425892