CoronaVR
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Predicted highly potential siRNAs


S.No. Target region Start position End position Sense Antisense Inhibition (%) Off-target (seed) Immunogenicity
1 E 26458 26476 gatcttctggtctaaacga tcgtttagaccagaagatc 83.90 21 Immunomodulatory
2 orf1ab 461 479 cagccctatgtgttcatca tgatgaacacatagggctg 76.12 69 Non-immunomodulatory
3 N 29111 29129 gaacaaacccaaggaaatt aatttccttgggtttgttc 69.90 214 Immunomodulatory
4 orf1ab 19066 19084 caagctgatgtagaatgga tccattctacatcagcttg 67.76 169 Non-immunomodulatory
5 orf1ab 850 868 ctaccctcttgagtgcatt aatgcactcaagagggtag 66.67 71 Non-immunomodulatory
6 orf1ab 7952 7970 cagcttatgtgtcaaccta taggttgacacataagctg 65.70 105 Non-immunomodulatory
7 orf1ab 10037 10055 acctcagctgttttgcaga tctgcaaaacagctgaggt 65.70 174 Non-immunomodulatory
8 orf1ab 16960 16978 ccacaagagcactatgtta taacatagtgctcttgtgg 65.34 65 Non-immunomodulatory
9 N 28954 28972 gaaccagcttgagagcaaa tttgctctcaagctggttc 65.17 194 Non-immunomodulatory
10 orf1ab 17388 17406 gagtgttgtcaatgccaga tctggcattgacaacactc 65.14 148 Non-immunomodulatory
11 orf1ab 12028 12046 gcagggtgctgtagacata tatgtctacagcaccctgc 65.13 67 Non-immunomodulatory
12 orf1ab 13714 13732 gattgtccagctgttgcta tagcaacagctggacaatc 65.00 153 Non-immunomodulatory
13 orf1ab 1400 1418 ggacctgagcatagtcttg caagactatgctcaggtcc 64.89 71 Non-immunomodulatory
14 orf1ab 12419 12437 gcaagagatggttgtgttc gaacacaaccatctcttgc 64.79 156 Non-immunomodulatory
15 orf1ab 12539 12557 gcatcagcattgtgggaaa tttcccacaatgctgatgc 64.77 174 Non-immunomodulatory
16 orf1ab 458 476 gaacagccctatgtgttca tgaacacatagggctgttc 64.63 148 Non-immunomodulatory
17 S 23795 23813 gattcaactgaatgcagca tgctgcattcagttgaatc 64.58 114 Non-immunomodulatory
18 S 22410 22428 gaaccattacagatgctgt acagcatctgtaatggttc 64.42 177 Non-immunomodulatory
19 S 22593 22611 ccaccagatttgcatctgt acagatgcaaatctggtgg 64.19 150 Non-immunomodulatory
20 S 24102 24120 gagacctcatttgtgcaca tgtgcacaaatgaggtctc 64.18 116 Non-immunomodulatory
21 orf1ab 18653 18671 gcacctgttgtctatgtga tcacatagacaacaggtgc 64.14 106 Non-immunomodulatory
22 orf1ab 19062 19080 acctcaagctgatgtagaa ttctacatcagcttgaggt 64.10 115 Non-immunomodulatory
23 M 26792 26810 gatgtggctcagctacttc gaagtagctgagccacatc 64.03 93 Non-immunomodulatory
24 N 28682 28700 ggagccttgaatacaccaa ttggtgtattcaaggctcc 64.03 59 Non-immunomodulatory
25 ORF8 27930 27948 gtagctgcatttcaccaag cttggtgaaatgcagctac 63.90 129 Non-immunomodulatory
26 orf1ab 11321 11339 gcatcagctgtagtgttac gtaacactacagctgatgc 63.87 122 Non-immunomodulatory
27 orf1ab 17183 17201 cactatgtgagaaggcatt aatgccttctcacatagtg 63.85 111 Non-immunomodulatory
28 orf1ab 19069 19087 gctgatgtagaatggaagt acttccattctacatcagc 63.67 186 Non-immunomodulatory
29 orf1ab 2888 2906 gtggcagatgctgtcataa ttatgacagcatctgccac 63.53 75 Non-immunomodulatory
30 orf1ab 12024 12042 ccatgcagggtgctgtaga tctacagcaccctgcatgg 63.52 121 Non-immunomodulatory
31 orf1ab 11372 11390 gatggtgctaggagagtgt acactctcctagcaccatc 63.49 146 Non-immunomodulatory
32 S 22232 22250 gaaccattggtagatttgc gcaaatctaccaatggttc 63.43 151 Non-immunomodulatory
33 ORF3a 25933 25951 gaacatgactaccagattg caatctggtagtcatgttc 63.37 125 Non-immunomodulatory
34 Non-coding 26518 26536 tagccatggcagattccaa ttggaatctgccatggcta 63.19 106 Non-immunomodulatory
35 orf1ab 17787 17805 acagaatgctgtagcctca tgaggctacagcattctgt 63.15 48 Non-immunomodulatory
36 orf1ab 13432 13450 catgcttcagtcagctgat atcagctgactgaagcatg 62.92 178 Immunomodulatory
37 orf1ab 16956 16974 agtgccacaagagcactat atagtgctcttgtggcact 62.87 72 Non-immunomodulatory
38 S 23649 23667 ctatgtcacttggtgcaga tctgcaccaagtgacatag 62.82 114 Non-immunomodulatory
39 S 24047 24065 gcagatgctggcttcatca tgatgaagccagcatctgc 62.79 108 Non-immunomodulatory
40 orf1ab 16286 16304 gtgcttgcatacgtagacc ggtctacgtatgcaagcac 62.68 0 Non-immunomodulatory
41 M 26795 26813 gtggctcagctacttcatt aatgaagtagctgagccac 62.68 114 Immunomodulatory
42 orf1ab 18184 18202 atgacctatagaagactca tgagtcttctataggtcat 62.67 92 Immunomodulatory
43 orf1ab 460 478 acagccctatgtgttcatc gatgaacacatagggctgt 62.63 144 Non-immunomodulatory
44 orf1ab 19390 19408 ccatgtgagtctcatggaa ttccatgagactcacatgg 62.58 117 Immunomodulatory
45 orf1ab 4893 4911 cattccacctagatggtga tcaccatctaggtggaatg 62.53 118 Non-immunomodulatory
46 3'UTR 29794 29812 ggaagagccctaatgtgta tacacattagggctcttcc 62.52 164 Non-immunomodulatory
47 orf1ab 12692 12710 gagcttagtcctgttgcac gtgcaacaggactaagctc 62.47 110 Non-immunomodulatory
48 S 24100 24118 tagagacctcatttgtgca tgcacaaatgaggtctcta 62.47 145 Non-immunomodulatory
49 orf1ab 17182 17200 gcactatgtgagaaggcat atgccttctcacatagtgc 62.46 158 Non-immunomodulatory
50 orf1ab 18334 18352 gaagctgttggtaccaatt aattggtaccaacagcttc 62.45 77 Immunomodulatory
51 orf1ab 411 429 gcacttgtggcttagtaga tctactaagccacaagtgc 62.43 104 Non-immunomodulatory
52 orf1ab 16959 16977 gccacaagagcactatgtt aacatagtgctcttgtggc 62.28 90 Non-immunomodulatory
53 orf1ab 14486 14504 gagagctaggtgttgtaca tgtacaacacctagctctc 62.24 49 Non-immunomodulatory
54 S 24985 25003 gcaacctgaattagactca tgagtctaattcaggttgc 62.19 59 Non-immunomodulatory
55 S 22635 22653 tcagcaactgtgttgctga tcagcaacacagttgctga 62.14 126 Non-immunomodulatory
56 orf1ab 2887 2905 tgtggcagatgctgtcata tatgacagcatctgccaca 62.09 117 Non-immunomodulatory
57 orf1ab 13720 13738 ccagctgttgctaaacatg catgtttagcaacagctgg 62.08 141 Non-immunomodulatory
58 orf1ab 9947 9965 gaagctgcttgttgtcatc gatgacaacaagcagcttc 61.99 147 Immunomodulatory
59 orf1ab 18185 18203 tgacctatagaagactcat atgagtcttctataggtca 61.99 93 Immunomodulatory
60 S 24099 24117 ctagagacctcatttgtgc gcacaaatgaggtctctag 61.98 166 Non-immunomodulatory
61 S 22413 22431 ccattacagatgctgtaga tctacagcatctgtaatgg 61.94 121 Non-immunomodulatory
62 orf1ab 10565 10583 gttcatgctggcacagact agtctgtgccagcatgaac 61.88 145 Non-immunomodulatory
63 orf1ab 849 867 gctaccctcttgagtgcat atgcactcaagagggtagc 61.85 141 Non-immunomodulatory
64 orf1ab 17923 17941 gttgctattaccagagcaa ttgctctggtaatagcaac 61.84 190 Non-immunomodulatory
65 orf1ab 16957 16975 gtgccacaagagcactatg catagtgctcttgtggcac 61.83 42 Non-immunomodulatory
66 orf1ab 18180 18198 ggacatgacctatagaaga tcttctataggtcatgtcc 61.78 98 Non-immunomodulatory
67 orf1ab 12694 12712 gcttagtcctgttgcacta tagtgcaacaggactaagc 61.76 125 Non-immunomodulatory
68 S 24724 24742 gtcagcacctcatggtgta tacaccatgaggtgctgac 61.71 110 Non-immunomodulatory
69 orf1ab 18318 18336 gtgtcatgctactagagaa ttctctagtagcatgacac 61.68 71 Non-immunomodulatory
70 orf1ab 2885 2903 gttgtggcagatgctgtca tgacagcatctgccacaac 61.60 153 Non-immunomodulatory
71 orf1ab 18317 18335 ggtgtcatgctactagaga tctctagtagcatgacacc 61.58 57 Non-immunomodulatory
72 ORF3a 26103 26121 tgatgagcctgaagaacat atgttcttcaggctcatca 61.56 179 Non-immunomodulatory
73 orf1ab 11319 11337 atgcatcagctgtagtgtt aacactacagctgatgcat 61.53 54 Non-immunomodulatory
74 orf1ab 8990 9008 gcaacatcagcttgtgttt aaacacaagctgatgttgc 61.46 156 Non-immunomodulatory
75 orf1ab 11317 11335 gtatgcatcagctgtagtg cactacagctgatgcatac 61.43 122 Non-immunomodulatory
76 N 28683 28701 gagccttgaatacaccaaa tttggtgtattcaaggctc 61.43 111 Non-immunomodulatory
77 orf1ab 18182 18200 acatgacctatagaagact agtcttctataggtcatgt 61.39 155 Non-immunomodulatory
78 orf1ab 19888 19906 agagatgctccagcacata tatgtgctggagcatctct 61.34 126 Non-immunomodulatory
79 orf1ab 8491 8509 gacatgtgcaactactaga tctagtagttgcacatgtc 61.28 36 Non-immunomodulatory
80 orf1ab 11344 11362 ccttatgacagcaagaact agttcttgctgtcataagg 61.25 99 Non-immunomodulatory
81 orf1ab 18664 18682 ctatgtgatagacgtgcca tggcacgtctatcacatag 61.23 35 Immunomodulatory
82 orf1ab 12025 12043 catgcagggtgctgtagac gtctacagcaccctgcatg 61.21 125 Non-immunomodulatory
83 orf1ab 12026 12044 atgcagggtgctgtagaca tgtctacagcaccctgcat 61.19 74 Non-immunomodulatory
84 5'UTR 261 279 gtaagatggagagccttgt acaaggctctccatcttac 61.18 155 Non-immunomodulatory
85 orf1ab 12559 12577 ccaacaggttgtagatgca tgcatctacaacctgttgg 61.15 69 Non-immunomodulatory
86 orf1ab 16178 16196 caaggtattgggaacctga tcaggttcccaataccttg 61.14 128 Non-immunomodulatory
87 orf1ab 18511 18529 ccttggaatgtagtgcgta tacgcactacattccaagg 61.11 9 Immunomodulatory
88 orf1ab 17480 17498 gcacactagaaccagaata tattctggttctagtgtgc 61.08 144 Non-immunomodulatory
89 orf1ab 13715 13733 attgtccagctgttgctaa ttagcaacagctggacaat 61.07 89 Non-immunomodulatory
90 S 23870 23888 atagctgttgaacaagaca tgtcttgttcaacagctat 61.07 73 Immunomodulatory
91 orf1ab 9225 9243 gcacttgtgaaagatcaga tctgatctttcacaagtgc 61.06 121 Non-immunomodulatory
92 N 28340 28358 tcaactggcagtaaccaga tctggttactgccagttga 61.06 73 Non-immunomodulatory
93 orf1ab 3390 3408 atgcagacattgtggaaga tcttccacaatgtctgcat 61.05 173 Non-immunomodulatory
94 orf1ab 12562 12580 acaggttgtagatgcagat atctgcatctacaacctgt 61.04 177 Non-immunomodulatory
95 orf1ab 15307 15325 gatagagccatgcctaaca tgttaggcatggctctatc 61.04 49 Non-immunomodulatory
96 orf1ab 16955 16973 tagtgccacaagagcacta tagtgctcttgtggcacta 61.01 93 Non-immunomodulatory
97 orf1ab 15862 15880 ggacctcatgaattttgct agcaaaattcatgaggtcc 60.99 163 Non-immunomodulatory
98 N 28949 28967 agattgaaccagcttgaga tctcaagctggttcaatct 60.99 91 Non-immunomodulatory
99 S 23126 23144 gcaactgtttgtggaccta taggtccacaaacagttgc 60.98 111 Immunomodulatory
100 N 28448 28466 catggcaaggaagacctta taaggtcttccttgccatg 60.95 113 Non-immunomodulatory
101 orf1ab 13403 13421 ggctgtagttgtgatcaac gttgatcacaactacagcc 60.92 92 Immunomodulatory
102 N 28347 28365 gcagtaaccagaatggaga tctccattctggttactgc 60.92 149 Non-immunomodulatory
103 orf1ab 20622 20640 agatggccatgtagaaaca tgtttctacatggccatct 60.91 71 Immunomodulatory
104 orf1ab 3303 3321 agatggaacttacaccagt actggtgtaagttccatct 60.88 117 Non-immunomodulatory
105 orf1ab 19060 19078 gtacctcaagctgatgtag ctacatcagcttgaggtac 60.88 100 Non-immunomodulatory
106 orf1ab 19061 19079 tacctcaagctgatgtaga tctacatcagcttgaggta 60.87 64 Non-immunomodulatory
107 S 24728 24746 gcacctcatggtgtagtct agactacaccatgaggtgc 60.83 70 Non-immunomodulatory
108 orf1ab 11352 11370 cagcaagaactgtgtatga tcatacacagttcttgctg 60.82 118 Non-immunomodulatory
109 orf1ab 19480 19498 ggtgctgtctgtagacatc gatgtctacagacagcacc 60.82 67 Non-immunomodulatory
110 orf1ab 2956 2974 agatgagtggagtatggct agccatactccactcatct 60.79 31 Non-immunomodulatory
111 orf1ab 15829 15847 gcaaaatgttggactgaga tctcagtccaacattttgc 60.79 153 Non-immunomodulatory
112 orf1ab 9381 9399 gtgctttggacatatcagc gctgatatgtccaaagcac 60.77 95 Immunomodulatory
113 orf1ab 12392 12410 gatgcactcaacaacatta taatgttgttgagtgcatc 60.77 120 Non-immunomodulatory
114 orf1ab 4894 4912 attccacctagatggtgaa ttcaccatctaggtggaat 60.74 156 Non-immunomodulatory
115 orf1ab 19056 19074 gtgtgtacctcaagctgat atcagcttgaggtacacac 60.72 203 Non-immunomodulatory
116 orf1ab 19068 19086 agctgatgtagaatggaag cttccattctacatcagct 60.72 240 Non-immunomodulatory
117 orf1ab 6626 6644 acccttgctactcatggtt aaccatgagtagcaagggt 60.71 101 Non-immunomodulatory
118 orf1ab 18505 18523 ggacttccttggaatgtag ctacattccaaggaagtcc 60.67 116 Non-immunomodulatory
119 S 24098 24116 gctagagacctcatttgtg cacaaatgaggtctctagc 60.63 196 Non-immunomodulatory
120 orf1ab 12161 12179 caggctgttgctaatggtg caccattagcaacagcctg 60.61 78 Non-immunomodulatory
121 orf1ab 3085 3103 gtttgagccatcaactcaa ttgagttgatggctcaaac 60.59 79 Non-immunomodulatory
122 M 26789 26807 cttgatgtggctcagctac gtagctgagccacatcaag 60.58 75 Non-immunomodulatory
123 orf1ab 4609 4627 gccacttggctatgtaaca tgttacatagccaagtggc 60.57 78 Non-immunomodulatory
124 orf1ab 16522 16540 acatgtgttggtagcgata tatcgctaccaacacatgt 60.57 5 Non-immunomodulatory
125 orf1ab 10256 10274 gtacaggctggtaatgttc gaacattaccagcctgtac 60.56 155 Non-immunomodulatory
126 orf1ab 2559 2577 cattagaacaacctactag ctagtaggttgttctaatg 60.54 48 Non-immunomodulatory
127 orf1ab 3084 3102 agtttgagccatcaactca tgagttgatggctcaaact 60.53 83 Non-immunomodulatory
128 S 23123 23141 ccagcaactgtttgtggac gtccacaaacagttgctgg 60.53 144 Immunomodulatory
129 orf1ab 19481 19499 gtgctgtctgtagacatca tgatgtctacagacagcac 60.49 79 Immunomodulatory
130 S 23865 23883 ctggaatagctgttgaaca tgttcaacagctattccag 60.48 49 Non-immunomodulatory
131 orf1ab 12691 12709 tgagcttagtcctgttgca tgcaacaggactaagctca 60.42 122 Non-immunomodulatory
132 orf1ab 5008 5026 gcaagttgtggacatgtca tgacatgtccacaacttgc 60.39 57 Immunomodulatory
133 orf1ab 12637 12655 gcctcttattgtaacagct agctgttacaataagaggc 60.38 69 Non-immunomodulatory
134 S 22594 22612 caccagatttgcatctgtt aacagatgcaaatctggtg 60.38 194 Non-immunomodulatory
135 N 28659 28677 gcatcatatgggttgcaac gttgcaacccatatgatgc 60.38 88 Non-immunomodulatory
136 orf1ab 12693 12711 agcttagtcctgttgcact agtgcaacaggactaagct 60.37 62 Non-immunomodulatory
137 orf1ab 18183 18201 catgacctatagaagactc gagtcttctataggtcatg 60.36 132 Non-immunomodulatory
138 orf1ab 21004 21022 gcaactgtacatacagcta tagctgtatgtacagttgc 60.34 81 Non-immunomodulatory
139 orf1ab 5196 5214 gtaggtacatgtcagcatt aatgctgacatgtacctac 60.32 161 Non-immunomodulatory
140 orf1ab 13404 13422 gctgtagttgtgatcaact agttgatcacaactacagc 60.32 80 Immunomodulatory
141 orf1ab 12029 12047 cagggtgctgtagacataa ttatgtctacagcaccctg 60.30 97 Non-immunomodulatory
142 orf1ab 12157 12175 tgagcaggctgttgctaat attagcaacagcctgctca 60.30 134 Non-immunomodulatory
143 S 25261 25279 gctttgctgtatgaccagt actggtcatacagcaaagc 60.29 136 Non-immunomodulatory
144 orf1ab 16988 17006 gcttatacccaacactcaa ttgagtgttgggtataagc 60.27 78 Non-immunomodulatory
145 orf1ab 851 869 taccctcttgagtgcatta taatgcactcaagagggta 60.26 78 Non-immunomodulatory
146 N 29230 29248 cattggcatggaagtcaca tgtgacttccatgccaatg 60.24 130 Non-immunomodulatory
147 orf1ab 17149 17167 gtgtatacagcttgctctc gagagcaagctgtatacac 60.22 141 Non-immunomodulatory
148 orf1ab 457 475 tgaacagccctatgtgttc gaacacatagggctgttca 60.20 133 Non-immunomodulatory
149 orf1ab 3535 3553 catagctactaatggacca tggtccattagtagctatg 60.20 93 Non-immunomodulatory
150 orf1ab 462 480 agccctatgtgttcatcaa ttgatgaacacatagggct 60.19 133 Non-immunomodulatory
151 orf1ab 459 477 aacagccctatgtgttcat atgaacacatagggctgtt 60.15 127 Non-immunomodulatory
152 orf1ab 3729 3747 gtgctgaccctatacattc gaatgtatagggtcagcac 60.14 165 Non-immunomodulatory
153 ORF3a 25930 25948 tctgaacatgactaccaga tctggtagtcatgttcaga 60.14 86 Non-immunomodulatory
154 ORF3a 26107 26125 gagcctgaagaacatgtcc ggacatgttcttcaggctc 60.12 57 Immunomodulatory
155 orf1ab 2398 2416 gcactcaaagggattgtac gtacaatccctttgagtgc 60.11 103 Non-immunomodulatory
156 orf1ab 13435 13453 gcttcagtcagctgatgca tgcatcagctgactgaagc 60.11 73 Immunomodulatory
157 orf1ab 16288 16306 gcttgcatacgtagaccat atggtctacgtatgcaagc 60.11 47 Non-immunomodulatory
158 ORF3a 25592 25610 agagatggcaactagcact agtgctagttgccatctct 60.11 55 Non-immunomodulatory
159 orf1ab 11764 11782 tagcatagatgccttcaaa tttgaaggcatctatgcta 60.09 99 Non-immunomodulatory
160 orf1ab 12022 12040 ttccatgcagggtgctgta tacagcaccctgcatggaa 60.07 146 Non-immunomodulatory
161 M 26634 26652 gcctatgccaacaggaata tattcctgttggcataggc 60.04 128 Non-immunomodulatory
162 orf1ab 17922 17940 tgttgctattaccagagca tgctctggtaatagcaaca 60.03 194 Non-immunomodulatory
163 S 24103 24121 agacctcatttgtgcacaa ttgtgcacaaatgaggtct 60.01 81 Non-immunomodulatory
164 S 25267 25285 ctgtatgaccagttgctgt acagcaactggtcatacag 60.01 126 Non-immunomodulatory
165 orf1ab 4897 4915 ccacctagatggtgaagtt aacttcaccatctaggtgg 60.00 124 Non-immunomodulatory
166 N 29526 29544 aggcctaaactcatgcaga tctgcatgagtttaggcct 60.00 113 Non-immunomodulatory