PDB-ID 4OVZB
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Structure title | X-Ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of HCoV Papain-Like Proteases |
Source | SARS-related coronavirus |
Macromolecule name | Papain-like proteinase |
Experimental method | X-RAY DIFFRACTION |
Strucutre Molecular Weight | 72478 |
Residue Count | 632 |
Sequence | MEVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVG
GLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGP
VTDVFYKETSYTTTIK |
Chain length | 316 |
Chain Molecular Weight | 35568.3 |
Biological process | GO:0006508 |
Cellular Component | - |
Molecular Function | GO:0003968, GO:0004197, GO:0008234, GO:0008242, GO:0016740 |
Dep. Date | 1/28/2014 |
Rel. Date | 2014-04-30 201 |
Rev. Date | 2014-04-30 201 |
Expression Host | Escherichia coli |