DrugRepV Browse Page

DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for Arenaviridae are 171

DrugRepV_ID	Antiviral Name	Drug type	Primary Indication	Secondary Indication	Strain	Pathways	Assay	Activity	Clinical Status	References
DrugRepV_0605	Amlodipine	Cardiovascular agents	Hypertension	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (61 %)	Approved	23577127
DrugRepV_0606	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (51 %)	Approved	23577127
DrugRepV_0607	Biperiden	Nervous System	Parkinson disease	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (27 %)	Approved	23577127
DrugRepV_0608	Carprofen	Anti-inflammatory	Joint pain	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (50 %)	Approved, Withdrawn	23577127
DrugRepV_0609	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (34 %)	Approved	23577127
DrugRepV_0610	Dexbrompheniramine	Respiratory System	Allergies	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (74 %)	Approved	23577127
DrugRepV_0611	Dibucaine	Nervous System	Anesthesia	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (49 %)	Approved	23577127
DrugRepV_0612	Diphenoxylate	Alimentary Tract and Metabolism	Diarrhea	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (83 %)	Approved	23577127
DrugRepV_0613	Diphenylpyraline	Respiratory System	Allergies	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (22 %)	Approved	23577127
DrugRepV_0614	Dipivefrin	Sensory Organ	Glaucoma	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (90 %)	Approved	23577127
DrugRepV_0615	Dirithromycin	Antiinfectives For Systemic Use	Bacterial infections	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	No significant effect (0 %)	Approved	23577127
DrugRepV_0616	Erythromycin	Antiinfectives For Systemic Use	Bacterial infections	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (60 %)	Approved	23577127
DrugRepV_0617	Estradiol	Genito Urinary System and Sex Hormones	Vulvar and vaginal atrophy	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (50 %)	Approved	23577127
DrugRepV_0618	Fluoxetine	Nervous System	Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (76 %)	Approved, Vet approved	23577127
DrugRepV_0619	Ketotifen	Respiratory System	Atopic asthma | Conjunctivitis	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (33 %)	Approved	23577127
DrugRepV_0620	Levopropoxyphene	Respiratory-Tract-agents	Cough and associated respiratory tract disorders	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (79 %)	Withdrawn	23577127
DrugRepV_0621	Mycophenolate Mofetil	Immunosuppressant	Organ rejection (immunosuppressants)	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (69 %)	Approved, Investigational	23577127
DrugRepV_0622	Oxyphencyclimine	Alimentary Tract and Metabolism	Peptic ulcers	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (28 %)	Approved	23577127
DrugRepV_0623	Paroxetine	Nervous System	Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	No significant effect (6 %)	Approved, Investigational	23577127
DrugRepV_0624	Penbutolol	Cardiovascular agents	Arterial hypertension	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (67 %)	Approved, Investigational	23577127
DrugRepV_0625	Prochlorperazine	Nervous System	Nausea | Vomiting | Schizophrenia	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (70 %)	Approved	23577127
DrugRepV_0626	Protriptyline	Nervous System	Depressive disorder	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (28 %)	Approved	23577127
DrugRepV_0627	Toremifene	Antineoplastic and Immunomodulating Agents	Breast Cancer	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (76 %)	Approved, Investigational	23577127
DrugRepV_0628	Trihexyphenidyl	Nervous System	Parkinson Disease	Lassa virus	GP derived Pseudovirus	NA	Luciferase reporter assay	Decrease (52 %)	Approved	23577127
DrugRepV_0629	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0630	Biperiden	Nervous System	Parkinson disease	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0631	Carprofen	Anti-inflammatory	Joint pain	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Withdrawn	23577127
DrugRepV_0632	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0633	Diphenylpyraline	Respiratory System	Allergies	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0634	Dipivefrin	Sensory Organ	Glaucoma	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0635	Dirithromycin	Antiinfectives For Systemic Use	Bacterial infections	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0636	Erythromycin	Antiinfectives For Systemic Use	Bacterial infections	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0637	Estradiol	Genito Urinary System and Sex Hormones	Vulvar and vaginal atrophy	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0638	Fluoxetine	Nervous System	Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Vet approved	23577127
DrugRepV_0639	Ketotifen	Respiratory System	Atopic asthma | Conjunctivitis	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0640	Mycophenolate Mofetil	Immunosuppressant	Organ rejection (immunosuppressants)	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Investigational	23577127
DrugRepV_0641	Oxyphencyclimine	Alimentary Tract and Metabolism	Peptic ulcers	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0642	Paroxetine	Nervous System	Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Investigational	23577127
DrugRepV_0643	Trihexyphenidyl	Nervous System	Parkinson Disease	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_2069	Lacidipine	Cardiovascular agents	Hypertension	Lassa virus	LASVpv	NA	Luciferase reporter assay	Decrease (50 %)	Approved, Investigational	29899092
DrugRepV_2070	Phenothrin	NA	NA	Lassa virus	LASVpv	NA	Luciferase reporter assay	Decrease (50 %)	Experimental	29899092
DrugRepV_3669	2-phenyl-4-(1,1,2,2-tetrafluoroethyl)-3H-1,5-benzodiazepine	NA	NA	Lassa virus	NA	NA	Luciferase reporter assay	Decrease (40 %)	NA	21270170
DrugRepV_3677	NSC 62914	NA	NA	Lassa virus	Josiah	NA	RT-PCR	Decrease (98 %)	NA	22027648
DrugRepV_3692	BCX4430	NA	Ebola virus	Lassa virus	Josiah	NA	RT-PCR	Decrease (50 %)	Investigational	24590073
DrugRepV_3723	C795-0925	NA	NA	Lassa virus	Josiah	NA	RT-PCR	Decrease (50 %)	NA	25144302
DrugRepV_3724	D011-2120	NA	NA	Lassa virus	Josiah	NA	RT-PCR	Decrease (50 %)	NA	25144302
DrugRepV_3725	F694-1532	NA	NA	Lassa virus	Josiah	NA	RT-PCR	Decrease (50 %)	NA	25144302
DrugRepV_3726	OSU-03012	Anticancer	Brain cancer	Lassa virus	NA	NA	NA	Decrease	NA	25986249
DrugRepV_3727	AZD8055	NA	Cancer	Lassa virus	NA	NA	NA	Decrease	Investigational	25986249
DrugRepV_3728	TWS119	NA	NA	Lassa virus	NA	NA	NA	Decrease	NA	25986249
DrugRepV_3729	SU 4312	NA	NA	Lassa virus	NA	NA	NA	Decrease	NA	25986249
DrugRepV_3730	Falnidamol dihydrochloride	NA	Solid Tumor	Lassa virus	NA	NA	NA	Decrease	Investigational	25986249
DrugRepV_3731	Ki 8751	NA	NA	Lassa virus	NA	NA	NA	Decrease	NA	25986249
DrugRepV_3732	10-DEBC hydrochloride	NA	NA	Lassa virus	NA	NA	NA	Decrease	NA	25986249
DrugRepV_3733	OSU-03012	Anticancer	Brain cancer	Lassa virus	NA	NA	Immunoflourescence assay	Decrease (50 %)	NA	25986249
DrugRepV_3738	Falnidamol dihydrochloride	NA	Solid Tumor	Lassa virus	NA	NA	RT-PCR	Decrease (50 %)	Investigational	25986249
DrugRepV_3741	OSU-03012	Anticancer	Brain cancer	Lassa virus	NA	NA	RT-PCR	Decrease (50 %)	NA	25986249
DrugRepV_3742	Falnidamol	NA	Solid Tumor	Lassa virus	NA	NA	RT-PCR	Decrease (50 %)	Investigational	25986249
DrugRepV_3747	Falnidamol	NA	Solid Tumor	Lassa virus	NA	NA	Firefly luciferase assay	Decrease (50 %)	Investigational	25986249
DrugRepV_3750	Amiodarone Hydrochloride	Cardiovascular agents	Anginal and Arrhythmia	Lassa virus	NA	NA	Firefly luciferase assay	Decrease (50 %)	Approved	25986249
DrugRepV_3862	Favipiravir	Antiviral	Influenza virus	Lassa virus	Ba366	NA	NA	Decrease (50 %)	Investigational	27736754
DrugRepV_3863	Favipiravir	Antiviral	Influenza virus	Lassa virus	Josiah	NA	Immunohistochemical assay	Decrease (50 %)	Investigational	27736754
DrugRepV_3993	Genistein	Antihelmintic	Prostate cancer	Lassa virus	NA	NA	Luciferase assay	Decrease (90 %)	Investigational	21947546
DrugRepV_3996	Tyrphostin AG1478	NA	NA	Lassa virus	NA	NA	Luciferase assay	Decrease (100 %)	NA	21947546
DrugRepV_3999	Genistein-Tyrphostin AG1478	NA	NA	Lassa virus	NA	NA	Luciferase assay	Decrease (99 %)	NA	21947546
DrugRepV_5202	C795-0925	NA	NA	Lassa virus	Josiah	NA	Immunoflourescence assay	Decrease (50 %)	NA	25144302
DrugRepV_5203	D011-2120	NA	NA	Lassa virus	Josiah	NA	Immunoflourescence assay	Decrease (50 %)	NA	25144302
DrugRepV_5204	F694-1532	NA	NA	Lassa virus	Josiah	NA	Immunoflourescence assay	Decrease (50 %)	NA	25144302
DrugRepV_5205	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Lassa virus	Josiah	NA	Immunoflourescence assay	Decrease (50 %)	Approved	25144302
DrugRepV_5267	25-Hydroxycholesterol	NA	NA	Lassa virus	Josiah	NA	TCID50 assay	Decrease (>1.1 Log)	Experimental	27999160
DrugRepV_5268	25-Hydroxycholesterol	NA	NA	Lassa virus	Josiah	NA	TCID50 assay	Decrease (1.4 Log)	Experimental	27999160
DrugRepV_5269	Favipiravir	Antiviral	Influenza virus	Lassa virus	Josiah	NA	TCID50 assay	Decrease (90 %)	Investigational	26456301
DrugRepV_5270	Favipiravir	Antiviral	Influenza virus	Lassa virus	Josiah	NA	TCID50 assay	Decrease (90 %)	Investigational	26456301
DrugRepV_5271	Favipiravir	Antiviral	Influenza virus	Lassa virus	Josiah	NA	Survival assay	Increase	Investigational	26456301
DrugRepV_5272	Favipiravir	Antiviral	Influenza virus	Lassa virus	Josiah	NA	Survival assay	Increase	Investigational	26456301
DrugRepV_5273	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5274	diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5275	diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5276	1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5277	2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5278	1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5279	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5280	{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5281	4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5282	4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5283	4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5284	4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5285	4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5286	4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5287	1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5288	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5289	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5290	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5291	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5292	diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5293	diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5294	1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5295	2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5296	1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5297	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5298	{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5299	4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5300	4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5301	4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5302	4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5303	4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5304	4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5305	1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5306	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5307	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5308	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5345	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	NA	21616094
DrugRepV_5346	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	NA	21616094
DrugRepV_5347	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	NA	21616094
DrugRepV_5348	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	NA	21616094
DrugRepV_5353	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	NA	21616094
DrugRepV_5354	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	NA	21616094
DrugRepV_5355	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	NA	21616094
DrugRepV_5356	5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide	NA	NA	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	NA	21616094
DrugRepV_5361	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	Approved	21616094
DrugRepV_5362	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	Approved	21616094
DrugRepV_5363	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	Approved	21616094
DrugRepV_5364	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (50 %)	Approved	21616094
DrugRepV_5369	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	Approved	21616094
DrugRepV_5370	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	Approved	21616094
DrugRepV_5371	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	Approved	21616094
DrugRepV_5372	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Lassa virus	AV	NA	RT-PCR	Decrease (90 %)	Approved	21616094
DrugRepV_5377	2-deoxy-2-fluorocytidine	NA	NA	Lassa virus	Josiah	NA	Minigenome assays	Decrease (50 %)	NA	27771389
DrugRepV_5378	5-fluorouridine	NA	Cancer	Lassa virus	Josiah	NA	Minigenome assays	Decrease (50 %)	Experimental	27771389
DrugRepV_5379	8-Azaadenosine	NA	NA	Lassa virus	Josiah	NA	Minigenome assays	Decrease (50 %)	NA	27771389
DrugRepV_5380	8-Azidoadenosine	NA	NA	Lassa virus	Josiah	NA	Minigenome assays	Decrease (50 %)	NA	27771389
DrugRepV_5381	Toyocamycin	NA	NA	Lassa virus	Josiah	NA	Minigenome assays	Decrease (50 %)	Experimental	27771389
DrugRepV_5382	6-Azauridine	NA	Cancer	Lassa virus	Josiah	NA	Minigenome assays	Decrease (50 %)	NA	27771389
DrugRepV_5393	Zoniporide	NA	NA	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	NA	30700611
DrugRepV_5395	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Approved	30700611
DrugRepV_5397	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Approved	30700611
DrugRepV_5399	Apilimod	NA	Crohn's disease | Psoriasis | Psoriatic disorders	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Investigational	30700611
DrugRepV_5401	Arbidol	NA	Viral infection	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Investigational	30700611
DrugRepV_5403	Clomiphene	Genito Urinary System and Sex Hormones	Female infertility	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Approved	30700611
DrugRepV_5405	Sertraline	Nervous System	Depressive disorder | Post-traumatic stress disorder | Obsessive-compulsive disorder | Panic disorder | Premenstrual dysphoric disorder | Social anxiety disorder	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Approved	30700611
DrugRepV_5407	Toremifene	Antineoplastic and Immunomodulating Agents	Breast Cancer	Lassa virus	Josiah	NA	Luciferase assay	Decrease (50 %)	Approved, Investigational	30700611
DrugRepV_5420	Losmapimod	NA	Chronic Obstructive Pulmonary Disease	Lassa virus	Josiah	NA	TCID50 assay	Decrease (50 %)	Investigational	30953674
DrugRepV_5421	Losmapimod	NA	Chronic Obstructive Pulmonary Disease	Lassa virus	Josiah	NA	RT-qPCR	Decrease (50 %)	Investigational	30953674
DrugRepV_5422	Losmapimod	NA	Chronic Obstructive Pulmonary Disease	Lassa virus	LP	NA	NA	Decrease (50 %)	Investigational	30953674
DrugRepV_5423	Losmapimod	NA	Chronic Obstructive Pulmonary Disease	Lassa virus	803213	NA	NA	Decrease (50 %)	Investigational	30953674
DrugRepV_5424	Losmapimod	NA	Chronic Obstructive Pulmonary Disease	Lassa virus	GA391	NA	NA	Decrease (50 %)	Investigational	30953674
DrugRepV_5425	Losmapimod	NA	Chronic Obstructive Pulmonary Disease	Lassa virus	Josiah	NA	NA	Decrease (50 %)	Investigational	30953674
DrugRepV_5426	ST-193	NA	NA	Lassa virus	LP	NA	NA	Decrease (50 %)	NA	30953674
DrugRepV_5427	ST-193	NA	NA	Lassa virus	803213	NA	NA	Decrease (50 %)	NA	30953674
DrugRepV_5428	ST-193	NA	NA	Lassa virus	GA391	NA	NA	Decrease (50 %)	NA	30953674
DrugRepV_5429	ST-193	NA	NA	Lassa virus	Josiah	NA	NA	Decrease (50 %)	NA	30953674
DrugRepV_5508	Amuvatinib	NA	Cancer	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Investigational	31786250
DrugRepV_5509	Antimycin A	Antifungal	Fungal infections	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	NA	31786250
DrugRepV_5510	Azoxystrobin	NA	Fungal infections	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Experimental	31786250
DrugRepV_5511	Buparvaquone	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	NA	31786250
DrugRepV_5512	Dequalinium chloride hydrate	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	NA	31786250
DrugRepV_5513	Manassantin A	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	NA	31786250
DrugRepV_5514	Monensin sodium salt	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Experimental, Vet approved	31786250
DrugRepV_5515	Mubritinib	NA	Lung Neoplasm, Renal Neoplasm, Breast Neoplasm, Ovarian Neoplasm, and Pancreatic Neoplasm	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Investigational	31786250
DrugRepV_5516	Narasin	Antibacterial	Parasitic and bacterial infections	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Experimental	31786250
DrugRepV_5517	Papaverine hydrochloride	Genito Urinary System and Sex Hormones	Impotence | Vasospasms	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Approved, Investigational	31786250
DrugRepV_5518	Pimozide	Nervous System	Tourette Disorder	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Approved	31786250
DrugRepV_5519	Rotenone	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Vet approved	31786250
DrugRepV_5520	Spautin-1	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	NA	31786250
DrugRepV_5521	Valinomycin	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Experimental	31786250
DrugRepV_5522	Ziprasidone	Nervous System	Schizophrenia	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Approved	31786250
DrugRepV_5523	Tryptanthrin	NA	NA	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	NA	31786250
DrugRepV_5524	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Lassa virus	NA	NA	Gaussia luciferase (Gluc) Glow assay	Decrease (50 %)	Approved	31786250
DrugRepV_7894	Papaverine hydrochloride	Genito Urinary System and Sex Hormones	Impotence | Vasospasms	Lassa virus	NA	NA	GLuc assay	Decrease (50 %)	Approved, Investigational	31786250
DrugRepV_7895	Rotenone	NA	NA	Lassa virus	NA	NA	GLuc assay	Decrease (50 %)	Vet approved	31786250
DrugRepV_7896	Ziprasidone	Nervous System	Schizophrenia	Lassa virus	NA	NA	GLuc assay	Decrease (50 %)	Approved	31786250