HSPMDB010167 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID85281215 | 5-[dichloro(1-phenyl-1H-1,2,3,4-tetrazol-5-yl)methyl]-1-phenyl-1H-1,2,3,4-tetrazole | ClC(Cl)(C1=NN=NN1C1=CC=CC=C1)C1=NN=NN1C1=CC=CC=C1 | Bisphenol derivative | NA | NA | NA | 7.3 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010168 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID85281217 | 6-(piperidine-1-sulfonyl)-1,3-benzothiazol-2-amine | NC1=NC2=CC=C(C=C2S1)S(=O)(=O)N1CCCCC1 | Bisphenol derivative | NA | NA | NA | 14.7 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010169 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID85281218 | 2-(3-chloro-2-methylphenyl)-N-{4,6-dimethyl-3-oxo-2H,3H-[1,2]thiazolo[5,4-b]pyridin-2-yl}acetamide | CC1=CC(C)=C2C(=O)N(NC(=O)CC3=CC=CC(Cl)=C3C)SC2=N1 | Bisphenol derivative | NA | NA | NA | 26.2 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010170 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | MAL2-11B | 6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid | CC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1 | Bisphenol derivative | NA | NA | NA | 19.5 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010171 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID92277586 | 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol | CC(C)(C1=CC=C(O)C=C1)C1=CC=C(O)C=C1 | Bisphenol derivative | NA | NA | NA | 41.4 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010172 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID96022078 | 4-[2-(3-hydroxyphenyl)propan-2-yl]phenol | CC(C)(C1=CC=C(O)C=C1)C1=CC=CC(O)=C1 | Bisphenol derivative | NA | NA | NA | >100 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010173 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID99206586 | 4-(2-phenylpropan-2-yl)phenol | CC(C)(C1=CC=CC=C1)C1=CC=C(O)C=C1 | Bisphenol derivative | NA | NA | NA | >100 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010174 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID92206566 | 4-(2-(4-chlorophenyl)propan-2-yl)phenol | ClC1=CC=C(C=C1)C(C)(C)C1=CC=C(C=C1)O | Bisphenol derivative | NA | NA | NA | 100 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010175 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID93575587 | 4,4'-(propane-2,2-diyl)bis(methoxybenzene) | CC(C)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC | Bisphenol derivative | NA | NA | NA | >100 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010176 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID99206560 | 4,4'-(propane-2,2-diyl)bis(1-methoxy-2-methylbenzene) | CC(C)(C1=CC(=C(C=C1)OC)C)C1=CC(=C(C=C1)OC)C | Bisphenol derivative | NA | NA | NA | >100 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010177 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID99206561 | 1-methoxy-4-{2-[4-methoxy-3-(propan-2-yl)phenyl]propan-2-yl}-2-(propan-2-yl)benzene | COC1=CC=C(C=C1C(C)C)C(C)(C)C1=CC(C(C)C)=C(OC)C=C1 | Bisphenol derivative | NA | NA | NA | 26.7 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010178 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID96022079 | 4,4'-(cyclopropane-1,1-diyl)diphenol | C1(CC1)(C1=CC=C(C=C1)O)C1=CC=C(C=C1)O | Bisphenol derivative | NA | NA | NA | 18 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010179 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID99234230 | 4,4'-methylenediphenol | C(C1=CC=C(C=C1)O)C1=CC=C(C=C1)O | Bisphenol derivative | NA | NA | NA | 70.1 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010180 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID99234234 | 4,4'-oxydiphenol | O(C1=CC=C(C=C1)O)C1=CC=C(C=C1)O | Bisphenol derivative | NA | NA | NA | 37.7 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010181 | 21948801 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SID99234233 | 6,6'-thiobis(2,4-dichlorophenol) | NA | Bisphenol derivative | NA | NA | NA | 35.7 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010182 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | Bithionol | 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol | OC1=C(Cl)C=C(Cl)C=C1SC1=C(O)C(Cl)=CC(Cl)=C1 | MS2000 collection | 100 | NA | NA | 3.3 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010183 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | hexacholorophene | 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol | OC1=C(CC2=C(Cl)C(Cl)=CC(Cl)=C2O)C(Cl)=C(Cl)C=C1Cl | MS2000 collection | 100 | NA | NA | 1.7 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010184 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | 5,7 Dihydroxyisoflavone | 5,7-dihydroxy-3-phenyl-4H-chromen-4-one | OC1=CC(O)=C2C(OC=C(C2=O)C2=CC=CC=C2)=C1 | MS2000 collection | 20 | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010185 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | Quercetin | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | OC1=CC(O)=C2C(OC(=C(O)C2=O)C2=CC=C(O)C(O)=C2)=C1 | MS2000 collection | 40 | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010186 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | chloranil | tetrachlorocyclohexa-2,5-diene-1,4-dione | ClC1=C(Cl)C(=O)C(Cl)=C(Cl)C1=O | MS2000 collection | 80 | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010187 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | compound 7 | 2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)sulfanyl]-4-chlorophenol | OC1=C(SC2=CC(Cl)=CC(Br)=C2O)C=C(Cl)C=C1Br | Bisphenol derivative | 30% at 30 uM | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010188 | 22898086 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | compound 9 | 2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl]-4-chlorophenol | OC1=C(CC2=CC(Cl)=CC(Br)=C2O)C=C(Cl)C=C1Br | Bisphenol derivative | 50% at 30 uM | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010189 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | MAL2-11B tetrazole | 6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid | CC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 95% | NA | NA | 20-50 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010190 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | ML281-56 | benzyl 4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1-{[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl}-2,3-dihydro-1??-pyrimidine-5-carboxylate | CC1=[N](CC2=CC=C(C=C2)C2=NN=NN2)C(=O)NC(C2=CC=C(C=C2)C2=CC=CC=C2)=C1C(=O)OCC1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 99% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010191 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | ML282-61 | benzyl 4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1-[2-(1H-1,2,3,4-tetrazol-5-yl)ethyl]-2,3-dihydro-1??-pyrimidine-5-carboxylate | CC1=[N](CCC2=NN=NN2)C(=O)NC(C2=CC=C(C=C2)C2=CC=CC=C2)=C1C(=O)OCC1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 88% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010192 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | ML282-59 | methyl 4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1-[2-(1H-1,2,3,4-tetrazol-5-yl)ethyl]-2,3-dihydro-1??-pyrimidine-5-carboxylate | COC(=O)C1=C(NC(=O)[N](CCC2=NN=NN2)=C1C)C1=CC=C(C=C1)C1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 12% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010193 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | ML282-60 | methyl 4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1-{[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl}-2,3-dihydro-1??-pyrimidine-5-carboxylate | COC(=O)C1=C(NC(=O)[N](CC2=CC=C(C=C2)C2=NN=NN2)=C1C)C1=CC=C(C=C1)C1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 51% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010194 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | LR340-001 | benzyl 4-{4'-fluoro-[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1-[5-(1H-1,2,3,4-tetrazol-5-yl)pentyl]-2,3-dihydro-1??-pyrimidine-5-carboxylate | CC1=[N](CCCCCC2=NN=NN2)C(=O)NC(C2=CC=C(C=C2)C2=CC=C(F)C=C2)=C1C(=O)OCC1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 99% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010195 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | LR340-003 | benzyl 4-[4-(2H-1,3-benzodioxol-5-yl)phenyl]-6-methyl-2-oxo-1-[5-(1H-1,2,3,4-tetrazol-5-yl)pentyl]-2,3-dihydro-1??-pyrimidine-5-carboxylate | CC1=[N](CCCCCC2=NN=NN2)C(=O)NC(C2=CC=C(C=C2)C2=CC=C3OCOC3=C2)=C1C(=O)OCC1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 99% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010196 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | LR340-006 | benzyl 6-methyl-4-{2'-methyl-[1,1'-biphenyl]-4-yl}-2-oxo-1-[5-(1H-1,2,3,4-tetrazol-5-yl)pentyl]-2,3-dihydro-1??-pyrimidine-5-carboxylate | CC1=CC=CC=C1C1=CC=C(C=C1)C1=C(C(=O)OCC2=CC=CC=C2)C(C)=[N](CCCCCC2=NN=NN2)C(=O)N1 | Pyrimidinone-peptoid hybrid | 99% | NA | NA | NA | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010197 | 25440730 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity | NA | SMAL | Benzyl 1-(4-(1H-tetrazol-5-yl)benzyl)-6-methyl-4-(2'-methyl-[1,1'-biphenyl]-4-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate | N1N=NN=C1C1=CC=C(CN2C(NC(C(=C2C)C(=O)OCC2=CC=CC=C2)C2=CC=C(C=C2)C2=C(C=CC=C2)C)=O)C=C1 | Pyrimidinone-peptoid hybrid | NA | NA | NA | 5 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010198 | 19200446 | Hsp40 | TAg (Large T antigen) | Virus | NA | Inhibition of ATPase activity (DnaJ stimulated) | NA | MAL3-11B | 6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid | CC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1 | Pyrimidinone-peptoid hybrid | 75% at 300 uM | NA | NA | 100 | NA | NA | NA | NA | NA | ATPase assay | NA | NA |
HSPMDB010199 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Inhibition of ATPase activity (DnaJ stimulated) | NA | all-L-alpha-p5' | NA | NA | Peptides | 12% inhibition of DnaK ATPase | NA | NA | NA | NA | NA | NA | NA | DnaJ | ATPase assay | NA | NA |
HSPMDB010200 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Inhibition of ATPase activity (DnaJ stimulated) | NA | normal all-D alpha-p5' | NA | NA | Peptides | 44% inhibition of DnaK ATPase | NA | NA | NA | NA | NA | NA | NA | DnaJ | ATPase assay | NA | NA |
HSPMDB010201 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Inhibition of ATPase activity (DnaJ stimulated) | NA | retro all-D p5' | NA | NA | Peptides | NA | NA | NA | NA | NA | NA | NA | NA | DnaJ | ATPase assay | NA | NA |
HSPMDB010202 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Binding affinity | NA | all-L alpha-p5 | NA | NA | Peptides | NA | 37 | NA | NA | NA | NA | NA | NA | DnaJ | Fluorescence based binding assay | NA | NA |
HSPMDB010203 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Binding affinity | NA | normal all-D alpha-p5' | NA | NA | Peptides | NA | 6.8 | NA | NA | NA | NA | NA | NA | DnaJ | Fluorescence based binding assay | NA | NA |
HSPMDB010204 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Binding affinity | NA | all-L-alpha-p5' | NA | NA | Peptides | NA | 9.2 | NA | NA | NA | NA | NA | NA | DnaJ | Fluorescence based binding assay | NA | NA |
HSPMDB010205 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Binding affinity | NA | retro all-D p5'-alpha | NA | NA | Peptides | NA | 0.9 | NA | NA | NA | NA | NA | NA | DnaJ | Fluorescence based binding assay | NA | NA |
HSPMDB010206 | 9575139 | Hsp40 | DnaJ | Bacteria | Cytosol | Binding affinity | NA | retro all-D alpha-p5'' | NA | NA | Peptides | NA | 1.9 | NA | NA | NA | NA | NA | NA | DnaJ | Fluorescence based binding assay | NA | NA |
HSPMDB010207 | 12637539 | Hsp40 | DnaJ | Bacteria | Cytosol | Inhibition of chaperone activity | NA | RI1-17 | NA | NA | Peptides | NA | 1.4 | NA | NA | 2 | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010208 | 12637539 | Hsp40 | DnaJ | Bacteria | Cytosol | Inhibition of chaperone activity | NA | RI1-10 | NA | NA | Peptides | NA | 0.8 | NA | NA | 1 | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010209 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 1 | pentyl 3a,8b-dihydroxy-2-methyl-4-methylidene-1H,3aH,4H,8bH-indeno[1,2-b]pyrrole-3-carboxylate | CCCCCOC(=O)C1=C(C)NC2(O)C3=C(C=CC=C3)C(=C)C12O | Phenoxy-N-arylacetamides | NA | NA | NA | >30 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010210 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 2 | N-(4-chlorophenyl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine | ClC1=CC=C(NC2=NC(=CS2)C2=CC=CS2)C=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | >100 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010211 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 3 | 7-(2-chlorophenyl)-4-(furan-2-yl)-8-oxa-5,6-diazatricyclo[7.4.0.0²,?]trideca-1(9),4,10,12-tetraene | ClC1=C(C=CC=C1)C1OC2=C(C=CC=C2)C2CC(=NN12)C1=CC=CO1 | Phenoxy-N-arylacetamides | NA | NA | NA | >100 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010212 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 4 | N-(cyclohexa-1,5-dien-1-yl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine | C1CC=C(NC2=NC(=CS2)C2=CC=CS2)C=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | 22 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010213 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 5 | ethyl 3-[2-(2-chlorophenoxy)acetamido]benzoate | CCOC(=O)C1=CC=CC(NC(=O)COC2=CC=CC=C2Cl)=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | 0.62 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010214 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 6 | butyl 3-[2-(2,4-dichlorophenoxy)acetamido]benzoate | CCCCOC(=O)C1=CC(NC(=O)COC2=CC=C(Cl)C=C2Cl)=CC=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | 0.13 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010215 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 7 | methyl 3-[2-(2,4-dichlorophenoxy)acetamido]benzoate | COC(=O)C1=CC(NC(=O)COC2=CC=C(Cl)C=C2Cl)=CC=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | >32 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010216 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 8 | methyl 3-[2-(2,5-dichlorophenoxy)acetamido]benzoate | COC(=O)C1=CC=CC(NC(=O)COC2=C(Cl)C=CC(Cl)=C2)=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | 0.95 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010217 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 9 | propyl 3-[2-(2-chlorophenoxy)acetamido]benzoate | CCCOC(=O)C1=CC(NC(=O)COC2=CC=CC=C2Cl)=CC=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | 0.6 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |
HSPMDB010218 | 22546203 | Hsp40 | Hsp70-DnaJ | Bacteria | Cytosol and membrane | Inhibition of chaperone activity | NA | 10 | ethyl 3-[2-(4-chlorophenoxy)acetamido]benzoate | CCOC(=O)C1=CC(NC(=O)COC2=CC=C(Cl)C=C2)=CC=C1 | Phenoxy-N-arylacetamides | NA | NA | NA | >30 | NA | NA | NA | NA | DnaJ | Refolding assay (luciferase) | NA | NA |