HSPMdb Accession NoHSPMDB010197
PMID25440730
TargetHsp40
HSP NameTAg (Large T antigen)
OrganismVirus
Enzymatic activityInhibition of ATPase activity
Compound NameSMAL
IUPAC NameBenzyl 1-(4-(1H-tetrazol-5-yl)benzyl)-6-methyl-4-(2'-methyl-[1,1'-biphenyl]-4-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
SMILESN1N=NN=C1C1=CC=C(CN2C(NC(C(=C2C)C(=O)OCC2=CC=CC=C2)C2=CC=C(C=C2)C2=C(C=CC=C2)C)=O)C=C1
Class Pyrimidinone-peptoid hybrid
IC50 (µM)5
Type of Enzymatic AssayATPase assay
DiseaseViral infection

Structure



HSPMDB010197

SMAL

Physicochemical Properties