HSPMdb Accession NoHSPMDB010193
PMID25440730
TargetHsp40
HSP NameTAg (Large T antigen)
OrganismVirus
Enzymatic activityInhibition of ATPase activity
Compound NameML282-60
IUPAC Namemethyl 4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1-{[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl}-2,3-dihydro-1??-pyrimidine-5-carboxylate
SMILESCOC(=O)C1=C(NC(=O)[N](CC2=CC=C(C=C2)C2=NN=NN2)=C1C)C1=CC=C(C=C1)C1=CC=CC=C1
Class Pyrimidinone-peptoid hybrid
% Enzymatic Inhibition/Fold Change51%
Type of Enzymatic AssayATPase assay
DiseaseViral infection

Structure



HSPMDB010193

ML282-60

Physicochemical Properties