HSPMdb Accession NoHSPMDB010198
PMID19200446
TargetHsp40
HSP NameTAg (Large T antigen)
OrganismVirus
Enzymatic activity Inhibition of ATPase activity (DnaJ stimulated)
Compound NameMAL3-11B
IUPAC Name6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid
SMILESCC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1
Class Pyrimidinone-peptoid hybrid
% Enzymatic Inhibition/Fold Change75% at 300 uM
IC50 (µM)100
Type of Enzymatic AssayATPase assay
DiseaseViral infection

Structure



HSPMDB010198

MAL3-11B

Physicochemical Properties