HSPMdb Accession No | HSPMDB010189 |
PMID | 25440730 |
Target | Hsp40 |
HSP Name | TAg (Large T antigen) |
Organism | Virus |
Enzymatic activity | Inhibition of ATPase activity |
Compound Name | MAL2-11B tetrazole |
IUPAC Name | 6-{5-[(benzyloxy)carbonyl]-4-{[1,1'-biphenyl]-4-yl}-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl}hexanoic acid |
SMILES | CC1=C(C(NC(=O)N1CCCCCC(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1)C(=O)OCC1=CC=CC=C1 |
Class | Pyrimidinone-peptoid hybrid |
% Enzymatic Inhibition/Fold Change | 95% |
IC50 (µM) | 20-50 |
Type of Enzymatic Assay | ATPase assay |
Disease | Viral infection |