HSPMdb Accession NoHSPMDB010212
PMID22546203
TargetHsp40
HSP NameHsp70-DnaJ
OrganismBacteria
LocalizationCytosol and membrane
Enzymatic activityInhibition of chaperone activity
Compound Name4
IUPAC NameN-(cyclohexa-1,5-dien-1-yl)-4-(thiophen-2-yl)-1,3-thiazol-2-amine
SMILESC1CC=C(NC2=NC(=CS2)C2=CC=CS2)C=C1
ClassPhenoxy-N-arylacetamides
IC50 (µM)22
Site of InteractionDnaJ
Type of Enzymatic AssayRefolding assay (luciferase)

Structure



HSPMDB010212

4

Physicochemical Properties