NS3 Protein

NS3 is a multifunctional protein consisting of 618 amino acids, exhibiting protease, helicase, nucleoside 5′-triphosphatase (NTPase), and 5′-terminal RNA triphosphatase activities. It plays a crucial role in the processing of viral polyproteins and genome replication.The N-terminal 180 amino acids of NS3 form a serine protease domain, with NS2B acting as a membrane-anchoring cofactor essential for its proteolytic activity. The C-terminal domain of NS3 is involved in viral RNA replication. As a result, disrupting the NS3 protein proves fatal to the virus, making it a promising target for antiviral drugs.

i-DENV NS3 Predictor

This submission from allows user to submit one or more chemical compounds in SDF format. If the user is not having SDF file format and would like to convert the format, it can be done by using the conversion tool available on our website and paste it here.

User can visit the HELP page to see how to use this predictive algorithm.

Click on the example option to see how it works

Paste your structure(s) in SDF format

---

Contact Us