DrugRepV_3623 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Rift Valley fever virus | MP12 | NA | qRT-PCR | Decrease (50 %) | Approved, Investigational | 27654301 |
DrugRepV_3624 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Severe acute respiratory syndrome coronavirus | Toronto-2 | NA | qRT-PCR | Decrease (50 %) | Approved, Investigational | 27654301 |
DrugRepV_3625 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Influenza virus | Influenza A/California/7/2009 | | qRT-PCR | Decrease (50 %) | Approved, Investigational | 27654301 |
DrugRepV_3626 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Zika virus | Zika-016 | NA | qRT-PCR | Decrease (50 %) | Approved, Investigational | 27654301 |
DrugRepV_3933 | IHVR-19029 | NA | NA | Zika virus | PRVABC-59 | NA | qRT-PCR | Decrease (50 %) | NA | 29253498 |
DrugRepV_3951 | Favipiravir | Antiviral | Influenza virus | Marburg virus | NA | NA | qRT-PCR | Decrease (50 %) | Investigational | 29369776 |
DrugRepV_3952 | Favipiravir | Antiviral | Influenza virus | Marburg virus | NA | NA | qRT-PCR | Decrease | Investigational | 29369776 |
DrugRepV_4141 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Venturini | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4142 | 5-ethyl-3-{3-[(1E)-1-{[2-(morpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Venturini | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4143 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Venturini | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4144 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Congo 95 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4145 | 5-ethyl-3-{3-[(1E)-1-{[2-(morpholin-4-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Congo 95 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4146 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | Congo 95 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4147 | 5-ethyl-3-{3-[(1E)-1-(methoxyimino)ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | St. Martin 20235 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_4148 | 5-ethyl-3-{3-[(1E)-1-{[2-(piperidin-1-yl)ethoxy]imino}ethyl]phenyl}-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one | NA | NA | Chikungunya virus | St. Martin 20235 | NA | qRT-PCR | Decrease (50 %) | NA | 28619679 |
DrugRepV_5386 | Quinacrine | NA | Malaria | Giardiasis | Cutaneous leishmaniasis | Management of malignant effusions | Ebola virus | NA | NA | qRT-PCR | Decrease | Investigational | 31307979 |
DrugRepV_5473 | Remdesivir | Antiviral | Hepatitis C | Ebola | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Experimental | 32020029 |
DrugRepV_5474 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32020029 |
DrugRepV_5475 | Penciclovir | Antiinfectives For Systemic Use | Recurrent cold sores on the lips and face from Herpesvirus invections | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32020029 |
DrugRepV_5476 | Nitazoxanide | Antiparasitic products, Insectisides and Repellents | Diarrhea | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved, Investigational, Vet approved | 32020029 |
DrugRepV_5477 | Nafamostat | NA | Blood vessel coagulation | Hemorrhagic lesions | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Investigational | 32020029 |
DrugRepV_5478 | Favipiravir | Antiviral | Influenza virus | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Investigational | 32020029 |
DrugRepV_5483 | RK-33 | NA | NA | Zika virus | Asian/Cook Islands/2014 | NA | qRT-PCR | Decrease (50 %) | NA | 31936642 |
DrugRepV_5503 | Cepharanthine | Antiinflammatory and antineoplastic | Inflammatory disorders/Cancer | SARS Coronavirus-2 | GX_P2V/pangolin/2017/Guangxi | NA | qRT-PCR | Decrease (50 %) | NA | 32149769 |
DrugRepV_5504 | Selamectin | Antiparasitic | Vet-Antihelminthic | SARS Coronavirus-2 | GX_P2V/pangolin/2017/Guangxi | NA | qRT-PCR | Decrease | Vet approved | 32149769 |
DrugRepV_5505 | Mefloquine hydrochloride | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | GX_P2V/pangolin/2017/Guangxi | NA | qRT-PCR | Decrease | Approved, Investigational | 32149769 |
DrugRepV_6063 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Dengue virus | DENV-2 New guinea C | | qRT-PCR | Decrease (90 %) | Phase I | 27654301 |
DrugRepV_6096 | Doxorubicin | Antineoplastic and Immunomodulating Agents | Cancer | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | Approved | 20837762 |
DrugRepV_6097 | SA-3 | NA | NA | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6098 | SA-11 | NA | NA | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6099 | SA-17 | NA | NA | Dengue virus | New Guinea C (NGC) | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6100 | SA-17 | NA | NA | Dengue virus | New Guinea C | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_6106 | IHVR-19029 | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 29253498 |
DrugRepV_6150 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6151 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6152 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6153 | AR-12 | NA | Solid Tumors and Lymphoma | Dengue virus | NA | | qRT-PCR | Decrease | Phase I | 28666323 |
DrugRepV_6154 | Schisandrin A | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 28338050 |
DrugRepV_6155 | Schisandrin B | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 28338050 |
DrugRepV_6156 | Schisandrin C | NA | NA | Dengue virus | NA | | qRT-PCR | Decrease (50 %) | NA | 28338050 |
DrugRepV_7170 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | West Nile virus | KERN515 WN02 | | qRT-PCR | Decrease (50 %) | Phase I | 27654301 |
DrugRepV_7171 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Japanese encephalitis virus | SA14 | | qRT-PCR | Decrease (50 %) | Phase I | 27654301 |
DrugRepV_7172 | Benzodiazepine | Nervous System | Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tract and Pancrease. | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | Phase I | 27654301 |
DrugRepV_7206 | CCG-4088 | NA | NA | Yellow fever virus | YFV 17D | | qRT-PCR | Decrease (20 Fold) | NA | 19651907 |
DrugRepV_7207 | CCG-3394 | NA | NA | Yellow fever virus | YFV 17D | | qRT-PCR | Decrease (15 Fold) | NA | 19651907 |
DrugRepV_7216 | Doxorubicin | Antineoplastic and Immunomodulating Agents | Cancer | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | Approved | 20837762 |
DrugRepV_7217 | SA-3 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7218 | SA-11 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7219 | SA-17 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7220 | SA-17 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 20837762 |
DrugRepV_7242 | IHVR-19029 | NA | NA | Yellow fever virus | 17D | | qRT-PCR | Decrease (50 %) | NA | 29253498 |
DrugRepV_7782 | Chloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | nCoV-2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32194981 |
DrugRepV_7783 | Hydroxychloroquine | Antiparasitic products, Insectisides and Repellents | Malaria | SARS Coronavirus-2 | nCoV-2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32194981 |
DrugRepV_7786 | Suramin | Antiparasitic products, Insectisides and Repellents | Sleeping sickness | Onchocerciasis | SARS Coronavirus-2 | SARS-CoV-2/Leiden-0002 | NA | qRT-PCR | Decrease (50 %) | Investigational | 32513797 |
DrugRepV_7787 | Auranofin | Musculo-Skeletal System | Rheumatoid arthritis | SARS Coronavirus-2 | USA-WA1/2020 | NA | qRT-PCR | Decrease (50 %) | Approved | 32442105 |
DrugRepV_8275 | Digoxin | Cardiovascular agents | Arrhythmia | Zika virus | NA | NA | qRT-PCR | Decrease (50 %) | Approved | 32669655 |
DrugRepV_8276 | Ouabain | Cardiovascular agents | Atrial fibrillation and flutter | Heart failure | Zika virus | NA | NA | qRT-PCR | Decrease (50 %) | Approved | 32669655 |