Vhf10944 details

Gene vhfRNAi AccessionVhf10944
Gene SymbolPOLD2
Gene DescriptionDNA polymerase delta subunit 2 (EC 2.7.7.7) (DNA polymerase delta subunit p50)
Gene Name in PaperPOLD2
GroupHost Factor
Ensembl Gene IDENST00000406581 ENST00000452185 
UniProt IDP49005
Entrez Gene ID5425
GOView
Host OrganismHomo sapiens
Virus Virus full nameVaccinia virus
Virus AbbreviationVACV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*17,320
Confirmed Hits Number30
Score3.41
Unit% GFP
Methods Assay Type Cell-based
BioModel DescriptionBS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells
Confirmatory Screen DescriptionImmunoprecipitation
Primary Screen Description#GFP-positive cells > 3% for each of the pooled siRNAs
Note/CommentIdentification of Restriction Factors by Human Genome-Wide RNA Interference.
References Pubmed ID26242627
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)