RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10941 |
| Gene Symbol | AURKB | |
| Gene Description | Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B) | |
| Gene Name in Paper | AURKB | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000316199 ENST00000534871 ENST00000578549 ENST00000585124 | |
| UniProt ID | Q96GD4 | |
| Entrez Gene ID | 9212 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Vaccinia virus |
| Virus Abbreviation | VACV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 17,320 | |
| Confirmed Hits Number | 30 | |
| Score | 6.93 | |
| Unit | % GFP | |
| Methods | Assay Type | Cell-based |
| BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
| Confirmatory Screen Description | Immunoprecipitation | |
| Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
| Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
| References | Pubmed ID | 26242627 |