RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10940 |
| Gene Symbol | AMACR | |
| Gene Description | Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase) | |
| Gene Name in Paper | AMACR | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000335606 ENST00000382072 ENST00000382085 ENST00000506639 | |
| UniProt ID | Q9UHK6 | |
| Entrez Gene ID | 23600 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Vaccinia virus |
| Virus Abbreviation | VACV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 17,320 | |
| Confirmed Hits Number | 30 | |
| Score | 3.97 | |
| Unit | % GFP | |
| Methods | Assay Type | Cell-based |
| BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
| Confirmatory Screen Description | Immunoprecipitation | |
| Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
| Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
| References | Pubmed ID | 26242627 |