RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10939 |
| Gene Symbol | PDE4B | |
| Gene Description | cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32) | |
| Gene Name in Paper | PDE4B | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000329654 ENST00000341517 ENST00000371045 ENST00000423207 ENST00000480109 | |
| UniProt ID | Q07343 | |
| Entrez Gene ID | 5142 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Vaccinia virus |
| Virus Abbreviation | VACV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 17,320 | |
| Confirmed Hits Number | 30 | |
| Score | 6.47 | |
| Unit | % GFP | |
| Methods | Assay Type | Cell-based |
| BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
| Confirmatory Screen Description | Immunoprecipitation | |
| Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
| Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
| References | Pubmed ID | 26242627 |