RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10935 |
Gene Symbol | PDCL | |
Gene Description | Phosducin-like protein (PHLP) | |
Gene Name in Paper | PDCL | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000259467 | |
UniProt ID | Q13371 | |
Entrez Gene ID | 5082 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Vaccinia virus |
Virus Abbreviation | VACV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 17,320 | |
Confirmed Hits Number | 30 | |
Score | 4.19 | |
Unit | % GFP | |
Methods | Assay Type | Cell-based |
BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
Confirmatory Screen Description | Immunoprecipitation | |
Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
References | Pubmed ID | 26242627 |