RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10931 |
| Gene Symbol | PPP1R11 | |
| Gene Description | Protein phosphatase 1 regulatory subunit 11 (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase inhibitor 3) | |
| Gene Name in Paper | PPP1R11 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000376772 ENST00000383612 ENST00000431424 ENST00000431977 ENST00000436591 ENST00000437937 ENST00000448378 ENST00000452679 | |
| UniProt ID | O60927 | |
| Entrez Gene ID | 6992 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Vaccinia virus |
| Virus Abbreviation | VACV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 17,320 | |
| Confirmed Hits Number | 30 | |
| Score | 5.95 | |
| Unit | % GFP | |
| Methods | Assay Type | Cell-based |
| BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
| Confirmatory Screen Description | Immunoprecipitation | |
| Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
| Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
| References | Pubmed ID | 26242627 |