RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10930 |
Gene Symbol | SORCS3 | |
Gene Description | VPS10 domain-containing receptor SorCS3 | |
Gene Name in Paper | SORCS3 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000369699 ENST00000369701 | |
UniProt ID | Q9UPU3 | |
Entrez Gene ID | 22986 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Vaccinia virus |
Virus Abbreviation | VACV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 17,320 | |
Confirmed Hits Number | 30 | |
Score | 12.66 | |
Unit | % GFP | |
Methods | Assay Type | Cell-based |
BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
Confirmatory Screen Description | Immunoprecipitation | |
Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
References | Pubmed ID | 26242627 |