Vhf10930 details

Gene vhfRNAi AccessionVhf10930
Gene SymbolSORCS3
Gene DescriptionVPS10 domain-containing receptor SorCS3
Gene Name in PaperSORCS3
GroupHost Factor
Ensembl Gene IDENST00000369699 ENST00000369701 
UniProt IDQ9UPU3
Entrez Gene ID22986
GOView
Host OrganismHomo sapiens
Virus Virus full nameVaccinia virus
Virus AbbreviationVACV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*17,320
Confirmed Hits Number30
Score12.66
Unit% GFP
Methods Assay Type Cell-based
BioModel DescriptionBS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells
Confirmatory Screen DescriptionImmunoprecipitation
Primary Screen Description#GFP-positive cells > 3% for each of the pooled siRNAs
Note/CommentIdentification of Restriction Factors by Human Genome-Wide RNA Interference.
References Pubmed ID26242627
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)