RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10926 |
Gene Symbol | DPAGT1 | |
Gene Description | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase) | |
Gene Name in Paper | DPAGT1 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000354202 ENST00000409993 | |
UniProt ID | Q9H3H5 | |
Entrez Gene ID | 1798 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Vaccinia virus |
Virus Abbreviation | VACV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 17,320 | |
Confirmed Hits Number | 30 | |
Score | 7.53 | |
Unit | % GFP | |
Methods | Assay Type | Cell-based |
BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
Confirmatory Screen Description | Immunoprecipitation | |
Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
References | Pubmed ID | 26242627 |