RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10925 |
Gene Symbol | GNPDA2 | |
Gene Description | Glucosamine-6-phosphate isomerase 2 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 2) (GNPDA 2) (GlcN6P deaminase 2) (Glucosamine-6-phosphate isomerase SB52) | |
Gene Name in Paper | GNPDA2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000295448 ENST00000507534 ENST00000507917 ENST00000509756 | |
UniProt ID | Q8TDQ7 | |
Entrez Gene ID | 132789 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Vaccinia virus |
Virus Abbreviation | VACV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 17,320 | |
Confirmed Hits Number | 30 | |
Score | 5.68 | |
Unit | % GFP | |
Methods | Assay Type | Cell-based |
BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
Confirmatory Screen Description | Immunoprecipitation | |
Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
References | Pubmed ID | 26242627 |