Vhf10925 details

Gene vhfRNAi AccessionVhf10925
Gene SymbolGNPDA2
Gene DescriptionGlucosamine-6-phosphate isomerase 2 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 2) (GNPDA 2) (GlcN6P deaminase 2) (Glucosamine-6-phosphate isomerase SB52)
Gene Name in PaperGNPDA2
GroupHost Factor
Ensembl Gene IDENST00000295448 ENST00000507534 ENST00000507917 ENST00000509756 
UniProt IDQ8TDQ7
Entrez Gene ID132789
GOView
Host OrganismHomo sapiens
Virus Virus full nameVaccinia virus
Virus AbbreviationVACV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*17,320
Confirmed Hits Number30
Score5.68
Unit% GFP
Methods Assay Type Cell-based
BioModel DescriptionBS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells
Confirmatory Screen DescriptionImmunoprecipitation
Primary Screen Description#GFP-positive cells > 3% for each of the pooled siRNAs
Note/CommentIdentification of Restriction Factors by Human Genome-Wide RNA Interference.
References Pubmed ID26242627
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)