RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10924 |
| Gene Symbol | CDC37 | |
| Gene Description | Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] | |
| Gene Name in Paper | CDC37 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000222005 | |
| UniProt ID | Q16543 | |
| Entrez Gene ID | 11140 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Vaccinia virus |
| Virus Abbreviation | VACV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 17,320 | |
| Confirmed Hits Number | 30 | |
| Score | 7.87 | |
| Unit | % GFP | |
| Methods | Assay Type | Cell-based |
| BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
| Confirmatory Screen Description | Immunoprecipitation | |
| Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
| Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
| References | Pubmed ID | 26242627 |