RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10923 |
| Gene Symbol | MAPK14 | |
| Gene Description | Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a) | |
| Gene Name in Paper | MAPK14 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000229794 ENST00000229795 ENST00000310795 | |
| UniProt ID | Q16539 | |
| Entrez Gene ID | 1432 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Vaccinia virus |
| Virus Abbreviation | VACV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 17,320 | |
| Confirmed Hits Number | 30 | |
| Score | 3.68 | |
| Unit | % GFP | |
| Methods | Assay Type | Cell-based |
| BioModel Description | BS-C-1 (ATCC CCL-26) and HeLa (ATCC CCL-2) cells | |
| Confirmatory Screen Description | Immunoprecipitation | |
| Primary Screen Description# | GFP-positive cells > 3% for each of the pooled siRNAs | |
| Note/Comment | Identification of Restriction Factors by Human Genome-Wide RNA Interference. | |
| References | Pubmed ID | 26242627 |