Vhf10782 details

Gene vhfRNAi AccessionVhf10782
Gene SymbolGLIPR1L2
Gene DescriptionGLIPR1-like protein 2
Gene Name in PaperGLIPR1L2
GroupHost Factor
Ensembl Gene IDENST00000320460 
UniProt IDQ4G1C9
Entrez Gene ID144321
GOView
Host OrganismHomo sapiens
Virus Virus full nameSendai virus
Virus AbbreviationSeV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*581
Confirmed Hits Number59
Score73.00%
UnitTarget gene inhibition
Methods Assay Type Cell-based
BioModel DescriptionEmbryonic kidney HEK 293T cells for screening lentiviral-based short hairpin RNA (shRNA) human library of ~15,000 human genes (3 shRNAs per gene).
Confirmatory Screen DescriptionConfirmed hits were validated using independent siRNA and qRT-PCR.
Primary Screen Description#Assessing the transcriptional response at the SeV-induced interferon-b (IFNB1) promoter activity
Note/CommentIncreased infection(46)
References Pubmed ID23785285
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)