RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10762 |
Gene Symbol | WNT2B | |
Gene Description | Protein Wnt-2b | |
Gene Name in Paper | WNT2B | |
Group | Restriction Factor | |
Ensembl Gene ID | ENSG00000134245 | |
UniProt ID | Q93097 | |
Entrez Gene ID | 7482 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Sendai virus |
Virus Abbreviation | SeV | |
Taxonomy | View | |
Results | Phenotype | Inhibited infection |
Hits Number* | 581 | |
Confirmed Hits Number | 59 | |
Score | 75.80% | |
Unit | Target gene inhibition | |
Methods | Assay Type | Cell-based |
BioModel Description | Embryonic kidney HEK 293T cells for screening lentiviral-based short hairpin RNA (shRNA) human library of ~15,000 human genes (3 shRNAs per gene). | |
Confirmatory Screen Description | Not mentioned | |
Primary Screen Description# | Assessing the transcriptional response at the SeV-induced interferon-b (IFNB1) promoter activity | |
Note/Comment | Inhibited infection(13) | |
References | Pubmed ID | 23785285 |