Vhf10757 details

Gene vhfRNAi AccessionVhf10757
Gene SymbolNTF4
Gene DescriptionNeurotrophin-4
Gene Name in PaperNTF4
GroupRestriction Factor
Ensembl Gene IDENST00000593537 
UniProt IDP34130
Entrez Gene ID4909
GOView
Host OrganismHomo sapiens
Virus Virus full nameSendai virus
Virus AbbreviationSeV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*581
Confirmed Hits Number59
Score81.00%
UnitTarget gene inhibition
Methods Assay Type Cell-based
BioModel DescriptionEmbryonic kidney HEK 293T cells for screening lentiviral-based short hairpin RNA (shRNA) human library of ~15,000 human genes (3 shRNAs per gene).
Confirmatory Screen DescriptionNot mentioned
Primary Screen Description#Assessing the transcriptional response at the SeV-induced interferon-b (IFNB1) promoter activity
Note/CommentInhibited infection(13)
References Pubmed ID23785285
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)