Vhf10755 details

Gene vhfRNAi AccessionVhf10755
Gene SymbolCHN1
Gene DescriptionN-chimaerin
Gene Name in PaperCHN1
GroupRestriction Factor
Ensembl Gene IDENSG00000128656 
UniProt IDP15882
Entrez Gene ID1123
GOView
Host OrganismHomo sapiens
Virus Virus full nameSendai virus
Virus AbbreviationSeV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*581
Confirmed Hits Number59
Score56.80%
UnitTarget gene inhibition
Methods Assay Type Cell-based
BioModel DescriptionEmbryonic kidney HEK 293T cells for screening lentiviral-based short hairpin RNA (shRNA) human library of ~15,000 human genes (3 shRNAs per gene).
Confirmatory Screen DescriptionNot mentioned
Primary Screen Description#Assessing the transcriptional response at the SeV-induced interferon-b (IFNB1) promoter activity
Note/CommentInhibited infection(13)
References Pubmed ID23785285
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)