Vhf10753 details

Gene vhfRNAi AccessionVhf10753
Gene SymbolSAMD15
Gene DescriptionSterile alpha motif domain-containing protein 15
Gene Name in PaperC14orf174
GroupRestriction Factor
Ensembl Gene IDENSG00000100583 
UniProt IDQ9P1V8
Entrez Gene ID161394
GOView
Host OrganismHomo sapiens
Virus Virus full nameSendai virus
Virus AbbreviationSeV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*581
Confirmed Hits Number59
Score92.60%
UnitTarget gene inhibition
Methods Assay Type Cell-based
BioModel DescriptionEmbryonic kidney HEK 293T cells for screening lentiviral-based short hairpin RNA (shRNA) human library of ~15,000 human genes (3 shRNAs per gene).
Confirmatory Screen DescriptionNot mentioned
Primary Screen Description#Assessing the transcriptional response at the SeV-induced interferon-b (IFNB1) promoter activity
Note/CommentInhibited infection(13)
References Pubmed ID23785285
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)