Vhf10750 details

Gene vhfRNAi AccessionVhf10750
Gene SymbolHS6ST1
Gene DescriptionHeparan-sulfate 6-O-sulfotransferase 1
Gene Name in PaperHS6ST1
GroupRestriction Factor
Ensembl Gene IDENSG00000136720 
UniProt IDO60243
Entrez Gene ID9394
GOView
Host OrganismHomo sapiens
Virus Virus full nameSendai virus
Virus AbbreviationSeV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*581
Confirmed Hits Number59
Score84.60%
UnitTarget gene inhibition
Methods Assay Type Cell-based
BioModel DescriptionEmbryonic kidney HEK 293T cells for screening lentiviral-based short hairpin RNA (shRNA) human library of ~15,000 human genes (3 shRNAs per gene).
Confirmatory Screen DescriptionNot mentioned
Primary Screen Description#Assessing the transcriptional response at the SeV-induced interferon-b (IFNB1) promoter activity
Note/CommentInhibited infection(13)
References Pubmed ID23785285
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)