RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10678 |
| Gene Symbol | SLC6A4 | |
| Gene Description | Sodium-dependent serotonin transporter | |
| Gene Name in Paper | SLC6A4 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENSG00000108576 | |
| UniProt ID | P31645 | |
| Entrez Gene ID | 6532 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Rotavirus |
| Virus Abbreviation | RV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited infection |
| Hits Number* | Not mentioned | |
| Confirmed Hits Number | 522 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | Monkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes | |
| Confirmatory Screen Description | Confirmed hits were validated using siRNA and qRT-PCR. | |
| Primary Screen Description# | An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication. | |
| Note/Comment | Inhibited infection (522) | |
| References | Pubmed ID | 23733942 |