Vhf10586 details

Gene vhfRNAi AccessionVhf10586
Gene SymbolPPP2R5C
Gene DescriptionSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Gene Name in PaperPPP2R5C
GroupRestriction Factor
Ensembl Gene IDENSG00000078304 
UniProt IDQ13362
Entrez Gene ID5527
GOView
Host OrganismHomo sapiens
Virus Virus full nameRotavirus
Virus AbbreviationRV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*Not mentioned
Confirmed Hits Number522
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionMonkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes
Confirmatory Screen DescriptionConfirmed hits were validated using siRNA and qRT-PCR.
Primary Screen Description#An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication.
Note/CommentInhibited infection (522)
References Pubmed ID23733942
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)