Vhf10528 details

Gene vhfRNAi AccessionVhf10528
Gene SymbolMRS2
Gene DescriptionMagnesium transporter MRS2 homolog, mitochondrial
Gene Name in PaperMRS2
GroupRestriction Factor
Ensembl Gene IDENSG00000124532 
UniProt IDQ9HD23
Entrez Gene ID57380
GOView
Host OrganismHomo sapiens
Virus Virus full nameRotavirus
Virus AbbreviationRV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*Not mentioned
Confirmed Hits Number522
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionMonkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes
Confirmatory Screen DescriptionConfirmed hits were validated using siRNA and qRT-PCR.
Primary Screen Description#An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication.
Note/CommentInhibited infection (522)
References Pubmed ID23733942
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)