RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10486 |
Gene Symbol | KLRB1 | |
Gene Description | Killer cell lectin-like receptor subfamily B member 1 | |
Gene Name in Paper | KLRB1 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENSG00000111796 | |
UniProt ID | Q12918 | |
Entrez Gene ID | 3820 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Rotavirus |
Virus Abbreviation | RV | |
Taxonomy | View | |
Results | Phenotype | Inhibited infection |
Hits Number* | Not mentioned | |
Confirmed Hits Number | 522 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | Monkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes | |
Confirmatory Screen Description | Confirmed hits were validated using siRNA and qRT-PCR. | |
Primary Screen Description# | An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication. | |
Note/Comment | Inhibited infection (522) | |
References | Pubmed ID | 23733942 |