RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf10419 |
Gene Symbol | CCDC142 | |
Gene Description | Coiled-coil domain-containing protein 142 | |
Gene Name in Paper | CCDC142 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENSG00000135637 | |
UniProt ID | Q17RM4 | |
Entrez Gene ID | 84865 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Rotavirus |
Virus Abbreviation | RV | |
Taxonomy | View | |
Results | Phenotype | Inhibited infection |
Hits Number* | Not mentioned | |
Confirmed Hits Number | 522 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | Monkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes | |
Confirmatory Screen Description | Confirmed hits were validated using siRNA and qRT-PCR. | |
Primary Screen Description# | An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication. | |
Note/Comment | Inhibited infection (522) | |
References | Pubmed ID | 23733942 |