Vhf10384 details

Gene vhfRNAi AccessionVhf10384
Gene SymbolEIF2S1
Gene DescriptionEukaryotic translation initiation factor 2 subunit 1
Gene Name in PaperEIF2S1
GroupRestriction Factor
Ensembl Gene IDENSG00000134001 
UniProt IDP05198
Entrez Gene ID1965
GOView
Host OrganismHomo sapiens
Virus Virus full nameRotavirus
Virus AbbreviationRV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*Not mentioned
Confirmed Hits Number522
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionMonkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes
Confirmatory Screen DescriptionConfirmed hits were validated using siRNA and qRT-PCR.
Primary Screen Description#An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication.
Note/CommentInhibited infection (522)
References Pubmed ID23733942
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)