Vhf10350 details

Gene vhfRNAi AccessionVhf10350
Gene SymbolCOX7B
Gene DescriptionCytochrome c oxidase subunit 7B, mitochondrial
Gene Name in PaperCOX7B
GroupRestriction Factor
Ensembl Gene IDENSG00000131174 
UniProt IDP24311
Entrez Gene ID1349
GOView
Host OrganismHomo sapiens
Virus Virus full nameRotavirus
Virus AbbreviationRV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*Not mentioned
Confirmed Hits Number522
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionMonkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes
Confirmatory Screen DescriptionConfirmed hits were validated using siRNA and qRT-PCR.
Primary Screen Description#An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication.
Note/CommentInhibited infection (522)
References Pubmed ID23733942
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)