Vhf10255 details

Gene vhfRNAi AccessionVhf10255
Gene SymbolARPC1B
Gene DescriptionActin-related protein 2/3 complex subunit 1B
Gene Name in PaperARPC1B
GroupRestriction Factor
Ensembl Gene IDENSG00000130429 
UniProt IDO15143
Entrez Gene ID10095
GOView
Host OrganismHomo sapiens
Virus Virus full nameRotavirus
Virus AbbreviationRV
TaxonomyView
Results PhenotypeInhibited infection
Hits Number*Not mentioned
Confirmed Hits Number522
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionMonkey kidney MA104 cells (Cercopithecus aethiops epithelial kidney origin) for screening 21,181 genes
Confirmatory Screen DescriptionConfirmed hits were validated using siRNA and qRT-PCR.
Primary Screen Description#An optimized immunofluorescent detection of viral protein synthesis was used to evaluate virus replication.
Note/CommentInhibited infection (522)
References Pubmed ID23733942
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)