Vhf10213 details

Gene vhfRNAi AccessionVhf10213
Gene SymbolOXR1
Gene DescriptionOxidation resistance protein 1
Gene Name in PaperOXR1
GroupHost Factor
Ensembl Gene IDENST00000297447 ENST00000312046 ENST00000442977 ENST00000445937 ENST00000449762 ENST00000452423 ENST00000497705 ENST00000517566 ENST00000531443 
UniProt IDQ8N573
Entrez Gene ID55074
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)