Vhf10153 details

Gene vhfRNAi AccessionVhf10153
Gene SymbolNET4
Gene DescriptionNetrin-4 (Beta-netrin) (Hepar-derived netrin-like protein)
Gene Name in PaperNET4
GroupHost Factor
Ensembl Gene IDENST00000343702 ENST00000344911 ENST00000538383 ENST00000553059 
UniProt IDQ9HB63
Entrez Gene ID59277
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)