Vhf10140 details

Gene vhfRNAi AccessionVhf10140
Gene SymbolG6B
Gene DescriptionProtein G6b
Gene Name in PaperG6B
GroupHost Factor
Ensembl Gene IDENST00000375804 ENST00000375805 ENST00000375806 ENST00000375809 ENST00000375810 ENST00000375814 ENST00000383410 ENST00000383411 ENST00000383412 ENST00000400067 ENST00000400071 ENST00000411608 ENST00000415728 ENST00000415984 ENST00000417610 ENST00000422012 ENST00000425998 ENST00000426729 ENST00000428302 ENST00000431888 ENST00000433769 ENST00000435007 ENST00000436030 ENST00000437153 ENST00000440063 ENST00000444404 ENST00000445381 ENST00000447587 ENST00000449633 ENST00000451549 ENST00000455185 ENST00000457450 ENST00000457884 
UniProt IDO95866
Entrez Gene ID80739
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)