Vhf10089 details

Gene vhfRNAi AccessionVhf10089
Gene SymbolIN80C
Gene DescriptionINO80 complex subunit C (IES6 homolog) (hIes6)
Gene Name in PaperIN80C
GroupHost Factor
Ensembl Gene IDENST00000334598 ENST00000441607 ENST00000592173 
UniProt IDQ6PI98
Entrez Gene ID125476
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)