Vhf10020 details

Gene vhfRNAi AccessionVhf10020
Gene SymbolLCE1E
Gene DescriptionLate cornified envelope protein 1E (Late envelope protein 5)
Gene Name in PaperLCE1E
GroupHost Factor
Ensembl Gene IDENST00000368770 ENST00000368771 
UniProt IDQ5T753
Entrez Gene ID353135
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)