RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf10013 |
| Gene Symbol | BIN1 | |
| Gene Description | Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1) | |
| Gene Name in Paper | BIN1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000259238 ENST00000316724 ENST00000346226 ENST00000348750 ENST00000351659 ENST00000352848 ENST00000357970 ENST00000376113 ENST00000393040 ENST00000393041 ENST00000409400 | |
| UniProt ID | O00499 | |
| Entrez Gene ID | 274 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |